Item Tags Offensive
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When playing as Tainted Lost, only items that have this tag can appear. Note that not all items with the tag are purely offensive as per the definition of the word.
Activated Collectibles
Name | ID | Icon | Quote | Description | Quality |
---|---|---|---|---|---|
A Pony | 5.100.130 | Flight + dash attack | Passively grants flight and increases speed to 1.5. Upon use, Isaac charges in the direction the pony is facing, giving invulnerability during the charge and dealing damage to enemies hit. | 2 | |
Anarchist Cookbook | 5.100.65 | Summon bombs | Spawns six Troll Bombs around the room. | 1 | |
Best Friend | 5.100.136 | Friends 'till the end | Spawns a decoy Isaac that explodes after 5 seconds. Enemies will always target the decoy and ignore Isaac. | 1 | |
Blank Card | 5.100.286 | Card mimic | Copies the effect of the card or rune currently held by Isaac. Copies the effect of the card currently held by Isaac. The charge time is based on the power of the card. |
2 | |
Bob's Rotten Head | 5.100.42 | Reusable ranged bomb | Isaac holds a poison Bomb which can be thrown in the cardinal directions and explodes on impact. | 1 | |
Book of Secrets | 5.100.287 | Tome of knowledge | Gives the effect of Treasure Map, The Compass, or Blue Map for the duration of the current floor. If all effects are active, X-Ray Vision is provided for the floor instead. Highlights any Tinted Rocks and rocks with Crawl Space in the room. | 1 | |
Book of Shadows | 5.100.58 | Temporary invincibility | Creates a protective shield, nullifying all types of damage in the current room for 10 seconds. | 3 | |
Box of Spiders | 5.100.288 | It's a box of spiders | Spawns 1-4 Blue Spiders that deal 2.5× Isaac's damage to enemies. Spawns 4-8 Blue Spiders that deal 2× Isaac's damage to enemies. |
1 | |
Butter Bean | 5.100.294 | Reusable knock-back | Isaac farts and knocks back nearby enemies and projectiles. Enemies pushed into walls or obstacles take 12 damage. | 1 | |
Crack the Sky | 5.100.160 | Holy white death | Summons 5 beams of light in random locations on the ground, dealing large amounts of damage to any enemies that touch them. | 2 | |
Crystal Ball | 5.100.158 | I see my future | Reveals the map (except the Super Secret Room and Ultra Secret Room) and drops a Soul Heart or random card/rune. While held, increases the chance of finding a Planetarium. | 3 | |
D10 | 5.100.285 | Reroll enemies | Re-rolls all monsters in the room. Replaces all monsters in the room with weaker monsters. |
1 | |
D100 | 5.100.283 | REEROLLLLL! | Combines the effects of D4, The D6, and D20. Combines the effects of D1, D4, The D6, D7, D8, D10, D12, and D20. |
3 | |
D20 | 5.100.166 | Reroll the basics | Rerolls all pickups in the current room. | 2 | |
D4 | 5.100.284 | Reroll into something else | Rerolls all of Isaac's passive items. | 2 | |
Dad's Key | 5.100.175 | Opens all doors... | Opens all doors in the current room in almost all circumstances, including doors which require a Key to open, entrances to Secret Rooms, and the door to Mega Satan. | 2 | |
Dead Sea Scrolls | 5.100.124 | It's a mystery | Triggers the effect of a random activated item from a list of possible options (not every activated item is included). | 1 | |
Deck of Cards | 5.100.85 | Reusable card generator | Gives Isaac a random card. | 2 | |
Doctor's Remote | 5.100.47 | Reusable air strike | Creates a crosshair on the ground that can be aimed with tear controls. A missile strikes the spot after 2 seconds, creating a heavy damage explosion. | 1 | |
Flush! | 5.100.291 | ... | Turns all non-boss monsters in the room into Poop. Instantly kills poop-themed bosses. Floods the current room. | 1 | |
Forget Me Now | 5.100.127 | I don't remember... | Restarts the current floor with a new layout. Isaac loses Forget Me Now, but keeps other items and consumables picked up on the original floor. | 3 | |
Guppy's Head | 5.100.145 | Reusable fly hive | Spawns 2-4 friendly Blue Flies that damage enemies. | 2 | |
Head of Krampus | 5.100.293 | Krampus rage | Fires a powerful Brimstone beam in four cardinal directions, much like Krampus shoots.
Fires a powerful Brimstone beam in four cardinal directions, much like Krampus shoots, with a 50% chance to rotate all beams around Isaac 90 degrees. |
2 | |
Isaac's Tears | 5.100.323 | Collected tears | Fires 8 tears around Isaac, which retain the damage, range, shot speed, and special tear effects of his tears. Each tear shot by Isaac increases item charge by one. Tears from this item have a +5 flat damage bonus. | 1 | |
Lemon Mishap | 5.100.56 | Oops... | Creates a tiny pool of yellow creep, damaging enemies that cross it. | 0 | |
Magic Fingers | 5.100.295 | Pay to win | Uses 1 Penny to deal damage to all enemies in the room. | 1 | |
Mom's Bottle of Pills | 5.100.102 | Reusable pill generator | Gives Isaac a random pill. | 1 | |
Mom's Bra | 5.100.39 | Mass paralysis | Petrifies all enemies in the current room for 4 seconds. | 1 | |
Mom's Pad | 5.100.41 | Mass fear | Inflicts fear to all enemies in the room for 4 seconds. Spawns a blue fly. | 0 | |
Monster Manual | 5.100.123 | Temporary buddy generator | Spawns a familiar from a specific selection for the current room. Spawns a familiar from a specific selection for the current floor. |
1 | |
Monstro's Tooth | 5.100.86 | Summon Monstro | A friendly Monstro jumps on a random enemy, dealing 120 area damage. Targets Isaac if used in a room without enemies. | 1 | |
Mr. Boom | 5.100.37 | Reusable bomb buddy | Places a Mr. Mega Bomb that deals 110 damage. Places a Mr. Mega Bomb that deals 185 damage. |
1 | |
My Little Unicorn | 5.100.77 | Temporary badass | Gives invulnerability and +0.28 speed for six seconds, removing the ability to shoot tears and replacing it with the ability to deal contact damage to enemies. | 1 | |
Notched Axe | 5.100.147 | Rocks don't stand a chance | Isaac destroys obstacles and opens Secret Rooms by walking into them, but cannot shoot or pick up items until it's cancelled. Toggles between tears and the pickaxe, which can be swung to attack and break obstacles. Using it depletes the charge, and it can't be used until next floor once the charge runs out. |
1 | |
Pandora's Box | 5.100.297 | ? ? | Spawns specific pickups or items depending on the floor it is used on. Disappears after use. | 2 | |
Portable Slot | 5.100.177 | Gamble 24/7 | Consumes 1 Penny and has a chance to drop a random pickup, like a Slot Machine. | 0 | |
Red Candle | 5.100.289 | Flame on | Throws out a flame that damages everything in its path, diminishing in size as it hits enemies or blocks shots. | 2 | |
Remote Detonator | 5.100.137 | Remote bomb detonation | Bombs placed by Isaac only explode when Remote Detonator is used. Gives 5 bombs. | 1 | |
Scissors | 5.100.325 | Lose your head | Turns Isaac's head into a stationary familiar for the current room which fires tears automatically. Isaac's body also shoots a controllable fountain of blood shots for the room. | 1 | |
Shoop da Whoop! | 5.100.49 | BLLLARRRRGGG! | Fires a laser from Isaac's mouth that deals twice Isaac's tear damage. | 2 | |
Spider Butt | 5.100.171 | Mass enemy slowdown + damage | Deals 10 damage to all enemies in the room and slows them for 4 seconds. Enemies killed by Spider Butt spawn Blue Spiders. | 1 | |
Tammy's Head | 5.100.38 | Reusable tear burst | Shoots 10 tears in a circle around Isaac, which retain the damage, range, shot speed, and special effects (such as poison) of Isaac's tears. Tears from this item have a +25 flat damage bonus. | 2 | |
Telepathy For Dummies | 5.100.192 | Temporary psychic shot | Gives homing tears for the current room. Also gives +3 range. | 1 | |
Teleport! | 5.100.44 | Teleport! | Teleports Isaac to a random room on the current floor. | 0 | |
The Bean | 5.100.111 | Toot on command | Isaac farts, poisoning any enemy in close range. | 0 | |
The Bible | 5.100.33 | Temporary flight | Grants flight for the current room. Instantly kills Mom, Mom's Heart, and It Lives when activated, but kills Isaac when used on Satan. | 1 | |
The Book of Belial | 5.100.34 | Temporary DMG up | +2 damage for the current room. Passively guarantees a Devil Room or Angel Room will appear while held. +2 damage for the current room. Passively increases the chance of finding a Devil Room or Angel Room while held. |
2 | |
The Book of Sin | 5.100.97 | Reusable item generator | Spawns a random coin, heart, bomb, key, battery, pill or card near Isaac. | 2 | |
The Boomerang | 5.100.338 | It will never leave you | Throws a boomerang which retrieves pickups, as well as damages and petrifies enemies hit for 2 seconds. | 1 | |
The Candle | 5.100.164 | Reusable flames | Throws out a flame that damages everything in its path, diminishing in size as it travels. | 2 | |
The D6 | 5.100.105 | Reroll your destiny | Re-rolls all items in the current room into other items, depending on the current room's Item Pool. | 4 | |
The Gamekid | 5.100.93 | Temporary Man-Pac | Turns Isaac into a Pac-Man-like creature for 6.5 seconds, granting invulnerability, inflicting fear on all enemies, and has a chance of replenishing a Half Red Heart every time an enemy is killed. | 1 | |
The Hourglass | 5.100.66 | Temporary enemy slowdown | All enemies in the room are slowed for 8 seconds. | 1 | |
The Necronomicon | 5.100.35 | Mass room damage | Deals 40 damage to every enemy in the room. | 1 | |
The Pinking Shears | 5.100.107 | Cut and run | Separates Isaac's head from his body for the current room, granting flight and turning the body into a familiar that chases enemies. | 2 | |
Undefined | 5.100.324 | Undefined | Teleports Isaac to the Secret Room, Super Secret Room, Treasure Room, or I AM ERROR. | 2 | |
We Need To Go Deeper! | 5.100.84 | Reusable level skip | Creates a trapdoor to go to the next floor. Once per floor, using it on tiles with special graphics will instead create a Crawl Space. | 2 | |
White Pony | 5.100.181 | Flight + holy death | Passively grants flight and increases speed to 1.5. Upon use, Isaac charges in the direction the pony is facing, giving invulnerability during the charge while also creating damaging beams of light. | 2 | |
Box of Friends | 5.100.357 | Double your friends | Duplicates all of Isaac's familiars for the current room. If Isaac has no familiars, spawns a Demon Baby for the room instead. | 1 | |
D12 | 5.100.386 | Rerolls rocks | Re-rolls all Rocks and Metal Blocks in the current room into other random obstacles. Re-rolls most types of Obstacles in the current room into other random obstacles. |
1 | |
D7 | 5.100.437 | Roll again | Restarts the current room and brings back all enemies, allowing more rewards to be acquired by completing the room. | 1 | |
D8 | 5.100.406 | Reroll stats | Re-rolls Isaac's damage, tears, range, and speed. | 2 | |
Diplopia | 5.100.347 | Double item vision | Duplicates all pickups and item pedestals in the room. | 3 | |
Friendly Ball | 5.100.382 | Gotta fetch 'em all! | Throwing the ball at a monster instantly kills and captures it. The captured enemy can later be released and will be friendly, fighting for Isaac and persisting between rooms. | 1 | |
Glass Cannon | 5.100.352 | Be gentle... | Fires a high-damage piercing spectral tear, but lowers Isaac's health to half a heart. Fires a high-damage piercing spectral tear. If Isaac takes damage while holding this, he takes extra damage and it becomes Broken Glass Cannon. |
1 | |
Glowing Hourglass | 5.100.422 | Turn back time | Rewinds time, putting Isaac back in the previous room and undoing anything that happened in the current room. Can only be used three times per floor, after which it functions like The Hourglass until the next floor. | 3 | |
Jar of Flies | 5.100.434 | Bug catcher | Killing an enemy adds a fly to the jar, up to a maximum of 20. On use, releases Blue Flies equal to the number of flies in the jar. | 2 | |
Kidney Bean | 5.100.421 | Love toots! | Isaac farts, charming all nearby enemies. | 1 | |
Mega Bean | 5.100.351 | Giga fart! | Petrifies all enemies in the current room for about 1.5 seconds, poisons any enemies near Isaac, and sends a rock wave across the room in the direction Isaac is facing. | 1 | |
Mega Blast | 5.100.441 | Laser breath | Isaac fires a giant laser for approximately 15 seconds. This laser deals massive damage, pushes Isaac backwards, and persists between rooms and floors. | 4 | |
Mine Crafter | 5.100.427 | Booom! | Places a Movable TNT barrel that can be pushed and used to destroy rocks or damage enemies. If used again in the same room while the previous TNT barrel is still intact, remotely detonates the TNT. | 1 | |
Mom's Box | 5.100.439 | What's inside? | Increases luck by 1 and doubles the effects of trinkets while held. When used, drops a random trinket on the ground. | 2 | |
Placebo | 5.100.348 | Pill mimic | Has the same effect as the Pill currently held by Isaac. The charge time is based on the power of the pill. | 2 | |
Tear Detonator | 5.100.383 | Remote tear detonation! | Splits all of Isaac's tears that are currently in the air into 6 tears that fire in all directions, which retain their damage and shot speed. | 1 | |
Teleport 2.0 | 5.100.419 | I-Teleport! | Teleports Isaac to a room that has not been explored yet. Normal rooms are prioritized over special rooms, and common special rooms take priority over rarer ones. | 3 | |
Ventricle Razor | 5.100.396 | Short cutter | Creates up to two portals that remain even if Isaac leaves the room. Upon entering a portal, Isaac is teleported to the other portal. | 1 | |
Wooden Nickel | 5.100.349 | Flip a coin | Has a roughly 50% chance to drop a penny, nickel or dime, and a roughly 50% chance to do nothing. | 1 | |
Black Hole | 5.100.512 | Nothing can escape | Throws a black hole on the ground which sucks in and damages enemies and destroys nearby obstacles. | 1 | |
Book of the Dead | 5.100.545 | Rise from the grave | Creates a friendly Bony, Black Bony, or an orbital bone for each enemy killed in the current room. Creates a friendly Bony, Black Bony, Bone Fly, Revenant, or an orbital bone for each enemy killed in the current room. |
3 | |
Broken Shovel | 5.100.550 | It feels cursed | While held, causes Mom to continuously attempt to stomp on Isaac. Activating makes her stop for the current room or wave. One of two parts necessary to create Mom's Shovel. | 4 | |
Brown Nugget | 5.100.504 | Friendly fly | Spawns a stationary fly turret that lasts for the current room and fires tears at nearby enemies. | 0 | |
Compost | 5.100.480 | Gain more friends! | Doubles Isaac's Blue Flies and Blue Spiders, or spawns one if Isaac has none. Converts pickups in the current room into Blue Flies or Blue Spiders. | 1 | |
Coupon | 5.100.521 | Allow 6 weeks for delivery | While held, guarantees one item in every Shop will be on sale. On use, makes a random item in the current room free. | 2 | |
Crooked Penny | 5.100.485 | 50/50 | Spawns a penny and has a 50% chance to double all items and pickups in the room. If the effect fails, the items and pickups disappear. | 2 | |
D infinity | 5.100.489 | Reroll forever | Grants a random die item that changes each use. Acts as any die item, and can by cycled by pressing the drop key. |
4 | |
D1 | 5.100.476 | What will it be? | Duplicates a random pickup in the room. The new pickup may be different than the original (i.e. a different card, etc). | 2 | |
Dataminer | 5.100.481 | 109 | Displaces enemy sprites for the current room, randomly increases one stat and decreases another. | 0 | |
Delirious | 5.100.510 | Unleash the power! | Spawns Delirium as a random friendly boss that fights for Isaac. | 1 | |
Eden's Soul | 5.100.490 | ... | Spawns two item pedestals then is consumed. Begins with no charges. | 3 | |
Mama Mega! | 5.100.483 | BOOOOOOOOOM! | Damages all enemies and destroys all obstacles. The effect occurs every time a new room is entered for the rest of the floor. Opens the doors to the floor's Secret Rooms and Super Secret Rooms. | 3 | |
Metronome | 5.100.488 | Waggles a finger | Grants a random item effect for the current room. | 1 | |
Mom's Shovel | 5.100.552 | Lost but not forgotten | Creates a trapdoor that leads to the next floor. Unlocks The Forgotten when used on a mound of dirt that appears in Dark Room. | 4 | |
Moving Box | 5.100.523 | Pack and unpack | If the box is empty, picks up items and pickups in a room and stores them. If the box is not empty, places all stored items and pickups in the current room. Can carry up to 10 items or pickups at once. | 1 | |
Mr. ME! | 5.100.527 | Caaan do! | Summons a controllable ghost that can perform various tasks depending on what it targets. | 3 | |
Mystery Gift | 5.100.515 | Wrapped up nice for you! | Spawns a random item from the current room's item pool, with a chance to spawn A Lump of Coal or The Poop instead. | 3 | |
Pause | 5.100.478 | Stop! | Freezes all enemies until a fire button is pressed. | 1 | |
Plan C | 5.100.475 | My last resort | Kills all enemies in the room, then kills Isaac three seconds later. | 0 | |
Sacrificial Altar | 5.100.536 | He demands a sacrifice | Sacrifices up to 2 familiars and spawns an item for each familiar sacrificed. Converts all friendly spiders and flies into coins. | 2 | |
Sharp Straw | 5.100.507 | More blood! | Damages all enemies in the room. Has a chance to drop a Half Red Heart or Half Soul Heart if an enemy is hit. Damages all enemies in the room. Has a chance to drop a Half Red Heart if an enemy is hit. |
2 | |
Smelter | 5.100.479 | Trinket melter! | Consumes Isaac's currently held trinket and applies its effect permanently. | 2 | |
Sprinkler | 5.100.516 | Sprinkles. | Creates a stationary sprinkler for the current room that rotates and fires tears in 8 directions. The tears copy Isaac's stats and most tear effects. | 2 | |
Telekinesis | 5.100.522 | Power of the mind | Any enemy shots that come near Isaac for the next three seconds are held in place then fired back. | 1 | |
Void | 5.100.477 | Consume | Consumes all pedestal items in the room. Active items will have their effects added to Void, and passive items will grant random stat upgrades. | 4 | |
Wait What? | 5.100.484 | I can't believe it's not butter bean! | Isaac farts, sending out a circular rock wave that destroys obstacles and hurts enemies. | 1 | |
Abyss | 5.100.706 | Come forth from the depths | Destroys all items in the room and gives Isaac a unique locust familiar for each item destroyed. Some items generate locusts with special effects. | 4 | |
Alabaster Box | 5.100.585 | A sacred offering | Spawns three Soul Hearts and two Angel Room items and is consumed. Starts with no charges, and can only be charged by picking up 6 Soul Hearts. | 2 | |
Anima Sola | 5.100.722 | Repent | Chains down the nearest enemy for 5 seconds, preventing them from acting. | 3 | |
Bag of Crafting | 5.100.710 | Make your destiny | Collects and holds up to 8 pickups, which can then be used to craft an item. The power level of the item is based on the quality of pickups used. | 3 | |
Berserk! | 5.100.704 | Rip and tear | Isaac goes berserk for 5 seconds, greatly increasing his speed, tears, and damage, but restricting him to using a melee weapon instead of his tears. This item charges by dealing damage to enemies instead of clearing rooms. | 2 | |
Book of Virtues | 5.100.584 | Spiritual companionship | Spawns a destroyable orbiting wisp familiar that fires tears and deals contact damage. Also acts as a passive item that causes other active items to spawn themed wisps. | 3 | |
Clear Rune | 5.100.263 | Rune mimic | Has the same effect as the rune or soul stone currently held by Isaac. The charge time is based on the power of the rune. | 2 | |
Damocles | 5.100.577 | A king's fortune... but at what cost? | Spawns a sword above Isaac's head, which doubles all item pedestals. After Isaac takes damage, the sword can randomly fall at any point, instantly killing him. | 2 | |
Dark Arts | 5.100.705 | One with the shadows | Briefly grants +1 speed and makes Isaac invulnerable and intangible. When the effect ends, destroys all projectiles and damages all enemies Isaac ran through. | 2 | |
Death Certificate | 5.100.628 | Where am I? | Takes Isaac to an abandoned and expanded version of Home, which has one copy of every item in the game. After taking an item, Isaac returns to the room he used Death Certificate in. | 4 | |
Decap Attack | 5.100.729 | Chuck away! | Throws Isaac's head, which is still able to fire tears at the spot it lands. Reactivating the item or stepping on the head reattaches it. | 2 | |
Eraser | 5.100.638 | Erase thy enemy | Throws an eraser that instantly kills the first monster it hits, and prevents that monster from spawning for the rest of the run. Deals 15 damage to bosses, erasing that boss if fatal. Can only be used once per floor. | 2 | |
Esau Jr. | 5.100.703 | Lost brother | Swaps between the current character and Esau Jr., who has +2 flat damage and flight. Characters have independent items and health. Dying as either character ends the run. | 2 | |
Eternal D6 | 5.100.609 | ??? | Rerolls all items in the room. Each item has a 25% chance to disappear instead. | 3 | |
Everything Jar | 5.100.720 | Anything is possible | Spawns certain pickups based on how many charges it has. If fully charged, instead has one of many unique effects. | 3 | |
Flip | 5.100.711 | Twist of fate | Item pedestals have a second uninteractable "ghostly" item behind them. Activating will flip the real and ghostly items around. If playing as Tainted Lazarus, also flips between them and Dead Tainted Lazarus. | 4 | |
Fortune Cookie | 5.100.557 | Reusable fortunes | Gives Isaac a fortune, Soul Heart, Card, Rune, or trinket, similar to a Fortune Telling Machine. Fortunes are much more likely to be given than anything else. | 2 | |
Free Lemonade | 5.100.578 | Party time! | Creates a large pool of yellow creep beneath Isaac. | 1 | |
Friend Finder | 5.100.687 | Best friends forever! | Spawns a random friendly monster that mimics Isaac's movements and attacks. | 3 | |
Gello | 5.100.728 | Demonic gestation | Spawns a demon familiar for the current room that's attached to Isaac and moves and fires in the direction Isaac shoots, using Isaac's damage, tears, range, shot speed, and special tear effects. | 3 | |
Genesis | 5.100.622 | In the beginning | Removes all of Isaac's items and pickups and takes him to a unique Bedroom with some pickups and Chests and a trapdoor to the next floor. For every item Isaac lost, he gets to take an item from a set of three. | 3 | |
Golden Razor | 5.100.555 | Pain from gain | Spends five Pennies to increase Isaac's damage by 1.2 for the current room. | 1 | |
Jar of Wisps | 5.100.685 | Your faith grows | Spawns random wisps that shoot various tears, block shots, and deal contact damage. The number of wisps spawned increases every time the jar is used. | 2 | |
Keeper's Box | 5.100.719 | Portable shop | Spawns a random shop item or pickup which can be bought for its normal price. | 2 | |
Larynx | 5.100.611 | Hear my pain | Isaac shouts, damaging and pushing away nearby enemies. The shout gets stronger the more charges the item has. Larynx gains 1 charge whenever Isaac takes damage, in addition to charging normally. | 2 | |
Lemegeton | 5.100.712 | Item summoner | Spawns a wisp representing a random passive item, which orbits Isaac but can be destroyed. While the wisp is alive, Isaac gains that item's effects. Generation uses the current room's item pool 25% of the time, otherwise a random pool. | 3 | |
Magic Skin | 5.100.642 | All your desires fulfilled | Consumes one heart container or two Soul Hearts to spawn an item and give Isaac a broken heart container that can never be filled. If Magic Skin isn't being held after being used, it is very likely to replace any future items. | 2 | |
Meat Cleaver | 5.100.631 | Slice but no dice | Splits all enemies in the room into two smaller versions of themselves with much less health. | 1 | |
Mega Mush | 5.100.625 | I'm a big boy now! | Gigantifies Isaac for 30 seconds, increasing damage and range while lowering tears, granting invulnerability, and allowing Isaac to crush enemies and obstacles he walks on. The effect persists between rooms. | 4 | |
Mom's Bracelet | 5.100.604 | Mother's strength | Lets Isaac pick up and throw rocks, TNT, Poops, friendly Dips, Bombs, and other obstacles. | 1 | |
Plum Flute | 5.100.650 | Play time! | Summons the boss Baby Plum to fight for Isaac in the current room. | 1 | |
R Key | 5.100.636 | Time to start over | Brings Isaac back to the first floor of a new run, retaining all of his items. | 4 | |
Red Key | 5.100.580 | Explore the other side | Creates a Red Room adjacent to a viable wall, indicated by the outline of a door. These rooms have a 10% chance to be a special room. | 3 | |
Sharp Key | 5.100.623 | Open your enemies | Adds 5 Keys on pickup. Allows Isaac to throw his keys to deal damage to enemies, destroy obstacles, and open doors. | 1 | |
Spindown Dice | 5.100.723 | -1 | Reduces the internal ID number of all items in the room by one, turning them into the item with that number. | 4 | |
Stitches | 5.100.635 | Bait and switch | Passively spawns a familiar that moves in the direction Isaac shoots. On use, Isaac swaps places with the familiar. | 1 | |
Sulfur | 5.100.556 | Temporary demon form | Grants Brimstone for the current room. | 3 | |
Suplex! | 5.100.709 | Angel breaker | Isaac dashes forward and picks up the first enemy hit. After a moment, he slams them into the ground to deal damage and create a circular rock wave. | 2 | |
The Scooper | 5.100.605 | Plop! | Summons The Peeper for the current room, which leaves a trail of red creep. | 1 | |
Urn of Souls | 5.100.640 | Unleash their sorrow | Spews a stream of damaging flame. Gains Soul Charges each time an enemy dies, which are used to fuel the urn. | 3 | |
Vade Retro | 5.100.653 | Begone! | While held, enemies leave behind ghosts on death. Stronger enemies leave bigger ghosts. Using the item causes the ghosts to explode and damage nearby enemies, and instantly kills all ghost enemies with less than 50% HP. | 2 | |
Wavy Cap | 5.100.582 | Tears up. A mind changing experience! | Increases fire rate, decreases speed, and distorts the screen. All effects become more pronounced with repeated use, and wear off by clearing rooms. | 1 |
Passive Collectibles
Name | ID | Icon | Quote | Description | Quality |
---|---|---|---|---|---|
???'s Only Friend | 5.100.320 | Controlled friend | Spawns a controllable familiar that deals 37.5 damage per second on touch. It can be moved using the shooting directional keys | 1 | |
20/20 | 5.100.245 | Double shot | Isaac fires two tears at once, one from each eye. 0.8× damage multiplier. | 4 | |
3 Dollar Bill | 5.100.191 | Rainbow tears | Gives Isaac a random tear effect every room. Gives Isaac a random tear effect every few seconds. |
2 | |
9 Volt | 5.100.116 | Quicker charge | Reduces the charge of any activated item by 1. Any 1 charge items instead have timed recharges. | 2 | |
A Dollar | 5.100.18 | $$$ | Gives Isaac 100 Pennies. | 3 | |
A Lump of Coal | 5.100.132 | My Xmas present | The more distance tears travel, the more damage they will do. | 3 | |
A Quarter | 5.100.74 | +25 coins | Gives Isaac 25 coins. | 0 | |
Abaddon | 5.100.230 | Evil + DMG up + fear shot | +1.5 damage, +0.2 speed. Removes all Red Heart containers, grants six Black Hearts, and adds a chance to shoot fear tears. +1.5 damage, +0.2 speed. Grants two Black Hearts, converts all Red Heart Containers into Black Hearts, and adds a chance to shoot fear tears. |
3 | |
Abel | 5.100.188 | Mirrored buddy | Spawns a familiar that mirrors Isaac's movements and shoots in the opposite direction. Spawns a familiar that mirrors Isaac's movements and shoots towards him. |
0 | |
Anti-Gravity | 5.100.222 | Anti-gravity tears + tears up | Tears float in position until firing ceases, after which they will fly off in the direction they were shot in. -2 Tear Delay. +1 Fire Rate. | 2 | |
Aquarius | 5.100.308 | Trail of tears | A trail of blue creep is left behind Isaac, which damages enemies. The creep scales with damage and inherits most tear effects. | 2 | |
Aries | 5.100.300 | Ramming speed | +0.25 Speed. Running into enemies while at a high speed will deal damage. Prevents Isaac from taking contact damage while moving at high speed. | 2 | |
Ball of Tar | 5.100.231 | Sticky feet... | Adds a chance to shoot slowing tears. Isaac leaves a trail of slowing creep behind as he moves, impeding enemies' speed. | 2 | |
BBF | 5.100.272 | Big Beautiful Fly | Spawns a familiar that flies around the room in a zig-zag pattern and explodes on contact with an enemy. Respawns after ten seconds. | 1 | |
BFFS! | 5.100.247 | Your friends rule! | Increases the size and effectiveness of most familiars. | 2 | |
Black Candle | 5.100.260 | Curse immunity + evil up | Prevents curses. Grants one Black Heart. Increases the chance for a Devil Room or Angel Room to appear. | 3 | |
Blood Clot | 5.100.254 | DMG + range up | Tears fired from the left eye have +1 flat damage, +5 range, and +0.5 tear falling speed. Tears fired from the left eye have +1 flat damage and +2.75 range. |
2 | |
Blood of the Martyr | 5.100.7 | DMG up | +1 damage. Isaac shoots blood tears. | 3 | |
Blue Cap | 5.100.342 | HP + tears up + shot speed down | Gives one full Red Heart container, +0.7 tears, and -0.16 shot speed. Heals 1 additional Red Heart. | 3 | |
Blue Map | 5.100.246 | Secrets | Reveals the locations of Secret Rooms and Super Secret Rooms on the map. | 2 | |
Bob's Brain | 5.100.273 | Explosive thoughts | Spawns a familiar that charges forward when shooting tears and explodes upon contact with an enemy, damaging and poisoning them. The familiar respawns after a few seconds. | 1 | |
Bob's Curse | 5.100.140 | +5 poison bombs | +5 Bombs. Grants Isaac's bombs a poison effect. They also leave a lingering poison cloud, and Isaac becomes immune to poison. | 1 | |
Bobby-Bomb | 5.100.125 | Homing bombs! | +5 Bombs. Bombs gain a homing effect, slowly moving towards the nearest enemy. | 2 | |
BOGO Bombs | 5.100.250 | 1+1 BOOM! | All normal Bombs become Double Bombs. | 1 | |
Bomb Bag | 5.100.131 | Gives bombs | Spawns a familiar that drops a Bomb every 3 rooms. | 2 | |
Boom! | 5.100.19 | 10 bombs | Grants 10 Bombs. | 0 | |
Box | 5.100.198 | Stuff | Spawns various pickups: 1 coin, 1 Key, 1 Bomb, 1 Heart, 1 card/rune, 1 pill and 1 trinket. | 0 | |
Brimstone | 5.100.118 | Blood laser barrage | Tears are replaced with a blood laser beam that pierces through all enemies and obstacles in its path and deals high damage. Can only be fired after a short charge-up period. | 4 | |
Brother Bobby | 5.100.8 | Friends 'till the end | Spawns a familiar that follows Isaac around shooting tears that deal 3.5 damage. He shoots more frequently than most familiars. | 1 | |
Bum Friend | 5.100.144 | He's greedy | Spawns a familiar that picks up coins for himself, giving random pickups in return. Can spawn Items from the Beggar Item Pool. | 1 | |
Butt Bombs | 5.100.209 | Toxic blast +5 bombs | +5 Bombs. Bombs now cloud up the screen, briefly damaging and confusing all enemies. | 2 | |
Caffeine Pill | 5.100.340 | Speed up + size down | Grants +0.3 speed, reduces Isaac's size, and gives a random pill. | 1 | |
Cain's Other Eye | 5.100.319 | Near-sighted friend | Spawns a familiar that slowly floats around the room on a zig-zag pattern and shoots normal tears in the same direction as Isaac. Spawns a familiar that follows Isaac and fires tears in random cardinal directions that copy Isaac's tears and tear effects and scale with damage. |
2 | |
Capricorn | 5.100.307 | All stats up | Adds 1 Red Heart Container, gives +0.5 Damage, +0.1 Speed, +1.5 Range, and -1.0 Tear Delay, and gives 1 Bomb, Penny, and Key. Adds 1 Red Heart Container, gives +0.5 Damage, +0.1 Speed, +0.75 Range, and +0.5 Fire Rate, and gives 1 Bomb, Penny, and Key. |
3 | |
Cat-o-nine-tails | 5.100.165 | Shot speed + damage up | +1 damage, +0.23 shot speed. | 3 | |
Ceremonial Robes | 5.100.216 | DMG + evil up | Grants 3 Black Hearts and +1 damage. | 3 | |
Champion Belt | 5.100.208 | DMG + challenge up | +1 damage. Increases the chance of champion enemies appearing by 15%. | 3 | |
Chemical Peel | 5.100.154 | DMG up | Tears fired from the left eye have +2 flat damage. | 2 | |
Chocolate Milk | 5.100.69 | Charge shots | Grants charged tears that deal greater damage when fully charged. | 3 | |
Contract From Below | 5.100.241 | Wealth... but at what cost? | Doubles the number of most room clear awards, but reduces the overall chance of getting one by 1/3. | 3 | |
Cricket's Body | 5.100.224 | Bursting shots + tears up | When tears hit an object or deplete their range, they spawn 4 smaller tears, whose range and damage scale with Isaac's. Grants -1 tear delay and reduces range. Grants +0.5 fire rate and reduces range. | 3 | |
Cricket's Head | 5.100.4 | DMG up | Increases Damage by 0.5, and increases damage multiplier by ×1.5. | 4 | |
Cupid's Arrow | 5.100.48 | Piercing shots | Grants Isaac piercing tears that travel through enemies (but not obstacles) instead of breaking on impact with them. | 3 | |
Cursed Eye | 5.100.316 | Cursed charge shot | Grants charged tears that can be fired in a tight burst. Getting hit while charging will teleport Isaac to another room. | 0 | |
Daddy Longlegs | 5.100.170 | Daddy's love | Daddy Long Legs' shadow follows Isaac and occasionally stomps enemies for 40 damage total. | 3 | |
Dark Matter | 5.100.259 | DMG up + fear shot | +1 damage, adds a chance to shoot fear tears. | 3 | |
Dead Onion | 5.100.336 | Toxic aura tears | Grants piercing and spectral tears. Increases tear size (without increasing damage) while greatly reducing range and shot speed. | 3 | |
Death's Touch | 5.100.237 | Piercing shots + DMG up | +1.5 damage, -0.3 tears. Tears are replaced with large piercing scythes. | 3 | |
Demon Baby | 5.100.113 | Auto-turret friend | Spawns a familiar that follows Isaac and automatically fires at enemies in its reach. | 2 | |
Distant Admiration | 5.100.57 | Attack fly | Spawns an attack fly that circles further out than Halo of Flies, but closer than Forever alone, dealing 75 damage per second. | 2 | |
Dr. Fetus | 5.100.52 | ??? | Tears are replaced by Bombs that benefit from bomb-enhancing effects and slide for a fixed time after being fired. | 4 | |
Epic Fetus | 5.100.168 | On-demand air strike | Instead of tears, firing creates a crosshair which can be moved freely. A missile is dropped in the location after 1.5 seconds, exploding for high damage. | 4 | |
Eve's Mascara | 5.100.310 | DMG up, tears + shot speed down | Doubles damage, halves tears stat, and greatly reduces shot speed. Doubles damage, 0.66x tears multiplier, and greatly reduces shot speed. |
3 | |
Experimental Treatment | 5.100.240 | Some stats up, some stats down | Randomly increases and decreases some of Isaac's stats. Increases four random stats and decreases the other two. |
1 | |
Fire Mind | 5.100.257 | Flaming tears | Grants flaming tears that deal burning damage over time. Tears have a chance to explode on impact with an enemy, which creates a fire at the location of the explosion. | 2 | |
Forever alone | 5.100.128 | Attack fly | Spawns an attack fly that orbits a long distance from Isaac, dealing 30 damage per second. | 1 | |
Gemini | 5.100.318 | Conjoined friend | Spawns a conjoined familiar which chases enemies close to Isaac, dealing ~6.43 damage per second. | 1 | |
Ghost Baby | 5.100.163 | Spectral buddy | Spawns a familiar that follows Isaac around and fires spectral tears. | 1 | |
Goat Head | 5.100.215 | He accepts your offering | A Devil Room / Angel Room will always spawn after every boss fight, excluding the first floor and floors after Chapter 4. | 3 | |
Godhead | 5.100.331 | God tears | Grants homing tears with a damaging halo. +0.5 Damage, -0.3 Tears -0.3 Shot Speed, +0.8 Tear Falling Speed, and +1.2 Range. Grants homing tears with a damaging halo. +0.5 Damage, -0.3 Tears, and -0.3 Shot Speed. |
4 | |
Growth Hormones | 5.100.70 | Speed + DMG up | +1 damage, +0.4 speed. +1 damage, +0.2 speed. |
3 | |
Guillotine | 5.100.206 | DMG + tears up. An out-of-body experience! | Isaac's head is removed from his body and floats around him as an orbital. Gives +1 damage and grants -1 tear delay. Gives +1 damage and grants +0.5 fire rate. | 2 | |
Guppy's Hairball | 5.100.187 | Swing it | Spawns a familiar that loosely follows behind Isaac, which blocks shots can be swung like a flail to damage enemies. Grows bigger by killing enemies. | 1 | |
Guppy's Tail | 5.100.134 | Cursed? | Room Clear Awards have a 1/3 chance of being replaced with a Chest and a 2/9 chance being replaced with nothing. | 2 | |
Harlequin Baby | 5.100.167 | Double shot buddy | Spawns a familiar that follows Isaac around and fires two tears at once in a V-pattern. | 1 | |
Headless Baby | 5.100.269 | Bloody friend | Spawns a familiar that follows Isaac, leaving blood creep on the ground. | 1 | |
Hive Mind | 5.100.248 | Giant spiders and flies | Increases the size of Blue Spiders and Blue Flies and doubles the amount of damage they deal. Also increases the effectiveness of fly and spider familiars. | 2 | |
Holy Water | 5.100.178 | Splash! | Spawns a bottle familiar that breaks when Isaac takes damage, leaving a puddle of blue creep. A bottle familiar that flies forward when Isaac shoots. It breaks upon hitting an enemy, leaving a puddle of blue creep that petrifies enemies. |
3 | |
Hot Bombs | 5.100.256 | Burning blast +5 bombs | +5 Bombs. Isaac's bombs leave behind fire that damages enemies upon contact. | 1 | |
Humbleing Bundle | 5.100.203 | 1+1 free 4Evar | Transforms Bombs, Keys, Pennies, and Red Hearts into their respective Double versions. This will occur 50% of the time. | 3 | |
Infestation 2 | 5.100.234 | Infestation shot | Spawns allied Blue Spiders from killed enemies. | 3 | |
Ipecac | 5.100.149 | Explosive shots | Replaces tears with explosive and poisoning projectiles fired in an arc from the mouth. | 4 | |
Iron Bar | 5.100.201 | DMG up + concussive tears | +0.3 damage. Adds a chance to shoot concussive tears, causing enemies to walk around randomly. | 2 | |
Jesus Juice | 5.100.197 | Damage + range up | +0.5 damage, +0.25 range, +0.5 tear falling speed. +0.5 damage, +1.5 range. |
2 | |
Juicy Sack | 5.100.266 | Sticky babies | Spawns a familiar that follows Isaac and drips a trail of slow creep, spawning 1-2 Blue Spiders after each room. | 2 | |
Key Piece 1 | 5.100.238 | ??? | Combined with Key Piece 2, unlocks the golden gate in the starting room of Chest and Dark Room to fight Mega Satan. | 0 | |
Key Piece 2 | 5.100.239 | ??? | Combined with Key Piece 1, unlocks the golden gate in the starting room of Chest and Dark Room to fight Mega Satan. | 0 | |
Latch Key | 5.100.343 | Luck up | Grants 1 Soul Heart and +1 luck. Spawns 2 Keys. | 1 | |
Leech | 5.100.270 | Blood sucker | Spawns a leech familiar that chases enemies, dealing ~3 damage per second. Heals a Half Red Heart whenever Leech kills an enemy. | 2 | |
Libra | 5.100.304 | You feel balanced | Gives 6 Coins, 6 Bombs, and 6 Keys and balances out all attributes. | 1 | |
Lil Brimstone | 5.100.275 | Evil friend | Grants a familiar that charges a thin Brimstone laser while Isaac is shooting. | 2 | |
Lil Haunt | 5.100.277 | Fear him | Spawns a familiar that chases down enemies, dealing 4 damage per second and inflicting fear. | 1 | |
Little Baggy | 5.100.252 | Extra pill room | Isaac can hold 2 pills at once and all cards and runes are replaced by pills. | 0 | |
Little Chubby | 5.100.88 | Attack buddy | Spawns a Charger familiar that charges forward and deals contact damage to any enemies in its path. | 2 | |
Little Gish | 5.100.99 | Sticky friend | Spawns a familiar that follows Isaac around and fires slowing tears, impeding enemies' speed. | 2 | |
Little Steven | 5.100.100 | Psychic friend | Spawns a familiar who follows Isaac around and fires homing tears. | 2 | |
Loki's Horns | 5.100.87 | Cross tears | Gives a random chance for projectiles to fire in all 4 cardinal directions. | 1 | |
Lost Contact | 5.100.213 | Shielded tears | Isaac's tears can hit and destroy enemy projectiles. -0.15 shot speed. | 2 | |
Lucky Foot | 5.100.46 | Luck up | +1 luck. Improves Isaac's chances at various random events (independent from the luck stat). Converts all bad pills into good pills, without identifying them. | 2 | |
Magic 8 Ball | 5.100.194 | Shot speed up | +0.16 shot speed, spawns a random tarot card. Increases the chance of finding a Planetarium. | 1 | |
Magic Mushroom | 5.100.12 | All stats up! | Makes Isaac bigger. Adds one Red Heart Container, +0.3 Damage, x1.5 damage multiplier, +5.25 Range, +0.3 Speed, and restores all Health. Makes Isaac bigger. Adds one Red Heart Container, +0.3 Damage, x1.5 damage multiplier, +2.5 Range, +0.3 Speed, and restores all Health. |
4 | |
Match Book | 5.100.344 | Evil up | Grants Isaac one Black Heart, spawns two or three Bombs. Also spawns Match Stick if it hasn't been encountered yet. | 1 | |
Mini Mush | 5.100.71 | Speed + range up | Decreases Isaac's size, making him less likely to be hit. +0.3 speed, +1.5 tear falling speed, -4.25 range (effective range is increased). +0.3 speed, +2.5 range. | 2 | |
Missing No. | 5.100.258 | Syntax error | Randomizes all passive items and stats upon pickup and at the start of each succeeding floor. | 0 | |
Mom's Coin Purse | 5.100.195 | What's all this...? | Spawns 4 random pills near Isaac. | 1 | |
Mom's Contacts | 5.100.110 | Freeze effect | Adds a chance to shoot petrifying tears, which stop enemies in place and prevent them from moving or attacking. +0.25 range. +1.5 range. | 3 | |
Mom's Eye | 5.100.55 | Eye in the back of your head | Gives Isaac a chance to fire tears from the back of his head. | 1 | |
Mom's Eyeshadow | 5.100.200 | Charm tears | Tears have a chance to charm enemies. | 1 | |
Mom's Heels | 5.100.30 | Range up | +5.25 range, +0.5 tear falling speed. +2.5 range, enemies that touch Isaac take 12 damage. |
1 | |
Mom's Key | 5.100.199 | Better chest loot +2 keys | Adds 2 keys. Chests will drop additional pickups. | 3 | |
Mom's Knife | 5.100.114 | Stab stab stab | Isaac's tears are replaced by a knife that pierces enemies, can travel through obstacles, and can hurt enemies while Isaac is holding it. Holding down the fire button before firing increases its range and power. | 4 | |
Mom's Lipstick | 5.100.31 | Range up | +5.25 range, +0.5 tear falling speed. +3.75 range. Spawns a Heart on pickup. |
1 | |
Mom's Perfume | 5.100.228 | Fear shot + tears up | Adds a chance to shoot fear tears. Decreases tear delay by 1. +0.5 fire rate. | 2 | |
Mom's Purse | 5.100.139 | More trinket room | Allows Isaac to hold one additional trinket. Drops a random trinket. | 2 | |
Mom's Underwear | 5.100.29 | Range up | +5.25 range, +0.5 tear falling speed. +2.5 range. Spawns 3-6 Blue Flies on pickup. |
1 | |
Mom's Wig | 5.100.217 | You feel itchy... | Adds a chance to spawn Blue Spiders when firing tears. Restores 1 Red Heart. | 2 | |
Money = Power | 5.100.109 | $$$ = DMG | Increases damage by 0.04 for every coin Isaac has, up to +3.96 damage at 99 coins. | 3 | |
Mongo Baby | 5.100.322 | Mongo friend | Spawns a familiar that copies the tears of Isaac's other familiars. | 2 | |
Monstro's Lung | 5.100.229 | Charged burst attack | Replaces normal tears with a charged shot that fires 14 tears in the same fashion as Monstro. | 2 | |
Mr. Mega | 5.100.106 | Bigger boom | +5 Bombs. Increases the size, blast radius, and damage of Isaac's bombs. | 2 | |
Mutant Spider | 5.100.153 | Quad shot | Isaac shoots four tears at once with lower fire rate. | 3 | |
My Reflection | 5.100.5 | Boomerang tears + DMG up + luck down | Gives Isaac's tears a boomerang effect. +1.5 range, +1 tear falling speed, x1.6 shot speed multiplier. 2x + 1.5 range, +1.5 damage, -1 luck, 1.6x shot speed multiplier. | 2 | |
Mysterious Liquid | 5.100.317 | Toxic splash damage | Tears leave a small, short lasting pool of creep on impact or when their range is depleted. | 3 | |
Mystery Sack | 5.100.271 | ? | Spawns a familiar that drops a Heart, coin, Bomb, or Key every 5-6 rooms. | 2 | |
Number One | 5.100.6 | Tears up + range down | Grants +1.5 tears, but severely reduces range. | 2 | |
Odd Mushroom | 5.100.121 | HP + DMG up, speed down | Grants one empty Heart container, +0.3 damage, +0.25 range, +0.5 tear falling speed, and -0.1 speed. Grants one full Heart container, +1 damage, +1.5 range, and -0.2 speed |
2 | |
Odd Mushroom | 5.100.120 | Tears + speed up, DMG down | +1.7 tears, +0.3 speed, slightly reduces damage. | 2 | |
Pageant Boy | 5.100.141 | Ultimate grand supreme | Spawns seven random coins around Isaac. | 0 | |
Pentagram | 5.100.51 | DMG up | +1 damage, increases Devil Room / Angel Room chance by 10%. | 3 | |
PHD | 5.100.75 | Better pills | Converts all bad pills into good pills, spawns one pill pickup, and identifies all pills. Restores two Red Hearts and increases the payout of Blood Donation Machines. | 2 | |
Pisces | 5.100.309 | Tears up + knock-back shots | -1 Tear Delay, adds knock-back shots and increases tear size. +0.5 Fire Rate, adds knock-back shots and increases tear size. |
2 | |
Polyphemus | 5.100.169 | Mega tears | Isaac fires huge tears that deal massive damage, but fire rate is greatly decreased. If a tear kills an enemy, it travels on with any leftover damage. | 4 | |
Proptosis | 5.100.261 | Short range mega tears | Tears start out massive with high damage, and then shrink down and become weaker over a short range. | 3 | |
Pyro | 5.100.190 | 99 bombs | Grants 99 Bombs. | 3 | |
Rainbow Baby | 5.100.174 | Random buddy | Spawns a familiar that follows Isaac around and fires tears with random effects. | 1 | |
Robo-Baby | 5.100.95 | Friends 'till the bbbbzzzt | Spawns a familiar that shoots Technology lasers. | 1 | |
Robo-Baby 2.0 | 5.100.267 | We worked out all the kinks | Spawns a familiar that fires lasers at any enemy in its line of sight and moves based on the direction Isaac is firing tears. | 1 | |
Roid Rage | 5.100.14 | Speed and range up | +0.6 speed, +5.25 range, +0.5 tear falling speed. +0.3 speed, +2.5 range |
2 | |
Rotten Baby | 5.100.268 | Infested friend | Spawns a familiar that spawns a Blue Fly when Isaac shoots. It can only have one Fly at a time. | 3 | |
Rubber Cement | 5.100.221 | Bouncing tears | Tears bounce off walls, enemies, and environmental objects. | 3 | |
Sack of Pennies | 5.100.94 | Gives money | Spawns a familiar that drops a coin every 2 rooms. | 1 | |
Sacred Heart | 5.100.182 | Homing shots + DMG up | Adds a Red Heart Container. Grants homing tears, a x2.3 Damage multiplier, +1 flat Damage, -0.4 Tears, -0.25 Shot Speed, and +4.125 Range. Adds a Red Heart Container. Grants homing tears, a x2.3 Damage multiplier, +1 flat Damage, -0.4 Tears, and -0.25 Shot Speed. |
4 | |
Sad Bombs | 5.100.220 | Tear blasts +5 bombs | +5 Bombs. Upon exploding, bombs shoot 10 tears around them, affected by tear modifiers. | 2 | |
Safety Pin | 5.100.339 | Evil + range + shot speed up | Grants one Black Heart, +5.25 range, +0.5 tear falling speed, +0.16 shot speed. Grants one Black Heart, +2.5 range, +0.16 shot speed. |
1 | |
Sagittarius | 5.100.306 | Piercing shots + speed up | Increases speed by +0.2 and grants piercing tears. | 3 | |
Scorpio | 5.100.305 | Poison tears | Grants poison tears, which deal damage over time when inflicted. | 3 | |
Screw | 5.100.255 | Tears + shot speed up | +0.5 tears, +0.2 shot speed. | 3 | |
Sissy Longlegs | 5.100.280 | She loves you | Spawns a familiar that wanders randomly, occasionally spawning Blue Spiders. Briefly charms enemies on contact. | 1 | |
Sister Maggy | 5.100.67 | Friends 'till the end | Spawns a familiar that follows Isaac around shooting tears that deal 3.5 damage. Spawns a familiar that follows Isaac around shooting tears that deal 6 damage. |
1 | |
Skeleton Key | 5.100.17 | 99 keys | Gives Isaac 99 Keys. | 3 | |
SMB Super Fan | 5.100.189 | All stats up | +1 Red Heart container, +0.3 damage, +0.2 tears, +0.2 speed, +0.5 range, +1 tear falling speed. Fully restores all red hearts. +1 Red Heart container, +0.3 damage, +0.2 tears, +0.2 speed, +2.5 range. Fully restores all red hearts. |
3 | |
Soy Milk | 5.100.330 | DMG down + tears way up | Tears are smaller and do much less damage, but fire in very rapid succession. | 2 | |
Speed Ball | 5.100.143 | Speed + shot speed up | +0.3 speed, +0.2 shot speed. | 2 | |
Spelunker Hat | 5.100.91 | See-through doors | Reveals type of adjacent rooms, including location for Secret Rooms and Super Secret Rooms. Reveals rooms up to 2 rooms away and blocks projectiles falling from above. | 2 | |
Spider Bite | 5.100.89 | Slow effect | Adds a chance to shoot slowing tears, reducing speed of enemy movement and any projectile fired by them. | 2 | |
Spoon Bender | 5.100.3 | Homing shots | Grants Isaac homing tears. | 3 | |
Squeezy | 5.100.196 | Tears up | +0.4 tears, spawns 2 Soul Hearts. | 3 | |
Starter Deck | 5.100.251 | Extra card room | Isaac can hold 2 cards at once and all pills are replaced by cards. | 2 | |
Steam Sale | 5.100.64 | 50% off | Reduces all Shop prices by 50%, rounded down to 7 coins for an item, rounded up to 2-3 coins for a pickup. | 2 | |
Steven | 5.100.50 | DMG up | +1 damage. | 3 | |
Strange Attractor | 5.100.315 | Magnetic tears | Pickups, trinkets, and monsters are magnetically attracted to Isaac's tears. | 0 | |
Synthoil | 5.100.345 | DMG + range up | +1 damage, +5.25 range, +0.5 tear falling speed. +1 damage, +2.5 range. |
3 | |
Tech.5 | 5.100.244 | It's still being tested... | Isaac occasionally fires an unlimited range piercing laser alongside his normal tears. The laser can glitch, mimicking the effects of certain items and trinkets. | 3 | |
Technology | 5.100.68 | Laser tears | Replaces tears with a piercing laser with unlimited range. | 3 | |
Technology 2 | 5.100.152 | Extra laser | Replaces the tears fired from Isaac's right eye with a rapid-firing low damage piercing laser. Damage down. | 2 | |
The Battery | 5.100.63 | Stores energy | Activated items can be overcharged, allowing them to store up to one extra use. | 2 | |
The Belt | 5.100.28 | Speed up | +0.3 speed. | 1 | |
The Common Cold | 5.100.103 | Poison damage | Adds a chance to shoot poison tears, dealing damage over time when inflicted. | 1 | |
The Compass | 5.100.21 | The end is near | Reveals the locations and types of all special rooms on the map, except Secret Rooms and Super Secret Rooms. | 2 | |
The Halo | 5.100.101 | All stats up | Grants one full Red Heart container, +0.3 damage, +0.2 tears, +0.25 range, +0.3 speed, and +0.5 tear falling speed. Grants one full Red Heart container, +0.3 damage, +0.2 tears, +1.5 range, and +0.3 speed. Heals 1 additional Red Heart. |
2 | |
The Inner Eye | 5.100.2 | Triple shot | Isaac shoots three tears at once with lower fire rate. | 2 | |
The Ludovico Technique | 5.100.329 | Controlled tears | Instead of firing tears, Isaac controls one floating tear that hover over obstacles. This tear deals constant damage when held in place over an enemy. | 2 | |
The Mark | 5.100.79 | DMG + speed up | Grants one Soul Heart, +1 damage, and +0.2 speed. Grants one Black Heart, +1 damage, and +0.2 speed. |
3 | |
The Mind | 5.100.333 | I know all | Reveals the entire map, including all special rooms and Secret Rooms. | 3 | |
The Mulligan | 5.100.151 | They grow inside | Tears have a 1/6 chance of spawning allied Blue Flies when they hit an enemy. | 3 | |
The Negative | 5.100.328 | Fate chosen | If Isaac has half a red heart or no red hearts after taking damage, all enemies in the room take significant damage. Allows entrance into the Dark Room. +1 Damage and also allows access to Home. | 2 | |
The Pact | 5.100.80 | DMG + tears up | Grants two Soul Hearts, +0.5 damage, and +0.7 tears. Grants two Black Hearts, +0.5 damage, and +0.7 tears. |
3 | |
The Parasite | 5.100.104 | Split shot | Isaac's tears split in two when they hit something. | 3 | |
The Peeper | 5.100.155 | Plop! | Spawns a familiar that slowly floats around the room in a zig-zag pattern, damaging enemies it passes through. Increases the damage of tears from Isaac's left eye by 35%. | 2 | |
The Polaroid | 5.100.327 | Fate chosen | If Isaac has half a red heart or no red hearts after taking damage, he gains a shield that nullifies all types of damage for 5 seconds. Allows entrance into Chest. Also allows access to Home. | 2 | |
The Sad Onion | 5.100.1 | Tears up | +0.7 tears. | 3 | |
The Small Rock | 5.100.90 | DMG up + speed down | +1 damage, +0.2 tears, -0.2 speed. | 3 | |
There's Options | 5.100.249 | More options | Two items appear after defeating a Boss. Only one can be taken; the other will disappear. | 3 | |
Tiny Planet | 5.100.233 | Orbiting tears + range up | Massively increases Range and grants spectral tears. Tears orbit around Isaac at a fixed distance until they hit the ground. | 0 | |
Tooth Picks | 5.100.183 | Tears + shot speed up | +0.7 tears, +0.16 shot speed. | 3 | |
Torn Photo | 5.100.341 | Tears + shot speed up | +0.7 tears, +0.16 shot speed. | 3 | |
Tough Love | 5.100.150 | Tooth shot | Adds a chance to shoot a tooth instead of a tear, which deals x3.2 Isaac's damage. | 3 | |
Treasure Map | 5.100.54 | Full visible map | Reveals the map of each floor. It does not identify special rooms and does not reveal the locations of Secret Rooms / Super Secret Rooms. | 2 | |
Whore of Babylon | 5.100.122 | Curse up | Grants +1.5 Damage and +0.3 Speed whenever Isaac has a Half Red Heart or less. | 2 | |
Wire Coat Hanger | 5.100.32 | Tears up | +0.7 tears. | 3 | |
Wooden Spoon | 5.100.27 | Speed up | +0.3 speed. | 1 | |
X-Ray Vision | 5.100.76 | I've seen everything | Reveals and opens all Secret Room and Super Secret Room entrances. | 2 | |
8 Inch Nails | 5.100.359 | Stick it to 'em! | +1.5 damage. Replaces Isaac's tears with nails, which have increased knockback. | 3 | |
Athame | 5.100.408 | Call to the void | When Isaac takes damage, a damaging black ring briefly appears around him. This ring can cause enemies to drop Black Hearts. After Isaac kills an enemy, adds a luck-based chance to spawn a damaging black ring around them. |
3 | |
Betrayal | 5.100.391 | Turn your enemy | Charms all enemies in the room when Isaac takes damage. Enemies are able to damage each other. If an enemy is damaged by another enemy, they will attack that enemy instead of Isaac. |
1 | |
Binky | 5.100.438 | Tears up | Grants one Soul Heart, +0.75 tears and decreases Isaac's size. | 3 | |
Black Powder | 5.100.420 | Spin the black circle! | Isaac leaves a trail of black powder on the floor. Walking in a circle will spawn a pentagram symbol on the floor, which deals 10 damage per tick to any enemies inside it. | 1 | |
Bomber Boy | 5.100.353 | Cross blast + 5 bombs | +5 Bombs. Isaac's bombs will now explode in a large cross-shaped pattern (roughly 5 bombs explosions wide). This also affects player-spawned Troll Bombs. | 2 | |
Bumbo | 5.100.385 | Bumbo want coin! | Spawns a beggar familiar which picks up any nearby coins, leveling up after collecting several coins. At level 2, Bumbo gains a body. At level 3, it begins to fire tears. At level 4, Bumbo follows enemies and gains contact damage. | 1 | |
Bursting Sack | 5.100.377 | Spider love | Spider enemies no longer target or deal contact damage to Isaac. | 1 | |
Car Battery | 5.100.356 | Active power up | Causes Isaac's activated item to activate twice on each use. | 3 | |
Chaos | 5.100.402 | !!! | Drops 1-6 random pickups on the floor. Causes items to be chosen from random item pools. | 3 | |
Charged Baby | 5.100.372 | Bbbzzzzzt! | Spawns a familiar that occasionally drops a Lil' Battery, gives an active item charge, or petrifies all enemies in the room. | 3 | |
Continuum | 5.100.369 | Transcendent tears | Grants spectral tears and increases range. Tears travel through walls and appear at the opposite side of the room. | 2 | |
Crown Of Light | 5.100.415 | The untainted gain power | +2 Soul Hearts. While Isaac has no empty red hearts, grants 2x damage, -0.3 shot speed, and increased range. Regardless of health, the crown deactivates for the current room when Isaac takes damage. | 4 | |
Dead Eye | 5.100.373 | Accuracy brings power! | Isaac's damage increases each time an enemy is hit. Damage is reset upon missing a shot. | 3 | |
Deep Pockets | 5.100.416 | More money! | Allows Isaac to carry two cards or pills (or a combination of both) at the same time. Increases the coin cap to 999. If a room would otherwise yield no reward, 1-3 coins will spawn. |
2 | |
Eden's Blessing | 5.100.381 | Tears up + your future shines brighter | +0.7 tears up. Grants a random item at the start of the next run. | 3 | |
Epiphora | 5.100.368 | Intensifying tears | Shooting in one direction increases Isaac's rate of fire until the cap is reached. As soon as Isaac changes direction or stops shooting, rate of fire is reset to its normal amount. | 2 | |
Evil Eye | 5.100.410 | Eye shot! | Adds a chance to fire a slow-moving eye that fires tears in the same direction as Isaac. The eye is destroyed when it hits an enemy or obstacle. | 2 | |
Explosivo | 5.100.401 | Sticky bomb shot! | Isaac's tears have a chance to stick to enemies and explode. | 3 | |
Fate's Reward | 5.100.361 | Your fate beside you | A blue head familiar that will follow Isaac and fire tears copying his tear effects and damage. | 2 | |
Friend Zone | 5.100.364 | Friendly fly | Spawns a white attack fly that orbits somewhere between Distant Admiration and Forever alone, dealing 45 damage per second. | 1 | |
Fruit Cake | 5.100.418 | Rainbow effects! | Isaac's tears gain a random effect that changes every shot. | 2 | |
GB Bug | 5.100.405 | Double tap glitch | Spawns a familiar that bounces diagonally around the room, applying a random status effect to enemies it hits and has a chance to re-roll pickups it passes over. Spawns a familiar that follows Isaac. Double tapping the fire button launches it forward, causing it to reroll the first monster or pickup it hits. |
1 | |
Glitter Bombs | 5.100.432 | Prize bombs! | +5 Bombs. Bombs have a chance to drop random pickups or charm enemies when they explode. | 2 | |
God's Flesh | 5.100.398 | Shrink shot! | Tears have a chance to shrink enemies, making them run away from Isaac. Shrunk enemies can be crushed and killed by walking over them. | 1 | |
Head of the Keeper | 5.100.429 | Penny tears! | Isaac's tears become coins and now have a chance to drop Pennies on the floor upon successfully hitting an enemy. | 2 | |
Holy Light | 5.100.374 | Holy death shot | Adds a chance to fire holy tears, which will create a damaging light beam in the area if they hit an enemy. | 3 | |
Incubus | 5.100.360 | Dark friend | Spawns a demonic familiar that shoots tears identical to Isaac's in terms of damage, tears, and tear effects. | 4 | |
Key Bum | 5.100.388 | He wants your keys! | Spawns a familiar that follows Isaac and collects Keys for himself, giving random Chests in return. | 0 | |
Kidney Stone | 5.100.440 | Matt's kidney stone | Isaac is occasionally forced to stop firing and charge an attack that launches a massive piercing, spectral kidney stone and a barrage of tears. -0.2 speed, decreases range. | 2 | |
Lil Chest | 5.100.362 | What's in the box? | Spawns a chest familiar that spawns a random pickup (25% chance) or trinket (10% chance) upon clearing a room. | 2 | |
Lil Gurdy | 5.100.384 | A gurd of your own! | A Gurdy Jr. familiar that charges up while Isaac is firing, bouncing around the room when released and dealing contact damage based on its speed. | 2 | |
Lil Loki | 5.100.435 | 4-way buddy! | Spawns a Loki familiar that follows Isaac and fires 4 tears in a cross pattern. | 1 | |
Lost Fly | 5.100.365 | Lost protector | Spawns a fly familiar that moves in a straight line and circles around the first wall or obstacle it hits. It deals 105 damage per second on contact. It deals 56 damage per second and forces nearby enemies to attack it. | 2 | |
Lusty Blood | 5.100.411 | Their blood brings rage! | Isaac's damage increases for the current room each time he kills an enemy. | 3 | |
Marked | 5.100.394 | Directed tears | Isaac will automatically fire tears directed at a red target on the ground. The target can be moved with tear controls. +0.7 tears, increases range. | 1 | |
Maw Of The Void | 5.100.399 | Consume thy enemy! | Charged by firing for 2.5 seconds and when released, creates a black ring around Isaac that rapidly deals damage. +1 damage, the ring can cause enemies to drop Black Hearts. | 3 | |
Mom's Pearls | 5.100.355 | Range + luck up | +1.25 range, +0.5 tear falling speed, +1 luck. +2.5 range, +1 luck. Grants one Soul Heart. |
2 | |
More Options | 5.100.414 | There's options | Two item pedestals are presented in every Treasure Room. Only one can be taken; the other will disappear. | 3 | |
Mr. Dolly | 5.100.370 | Range + tears up | +0.7 tears, +5.25 range, +0.5 tear falling speed, Spawns a combination of 3 Red Hearts, Soul Hearts or Black Hearts on the floor when picked up. +0.7 tears, +2.5 range, spawns 3 random types of Hearts on the floor when picked up. |
3 | |
Multidimensional Baby | 5.100.431 | ydduB Buddy | Spawns a familiar that will follow Isaac's movements on a 2.5-second delay. Tears that pass through the baby will be doubled and increase in speed. | 2 | |
My Shadow | 5.100.433 | Me! And my shaaaadow! | Inflicts fear on all enemies in the room upon taking damage and spawns black friendly Chargers that attack enemies. Spawns a shadow familiar that closely follows behind Isaac. It spawns a black friendly Charger whenever an enemy touches it. |
2 | |
Number Two | 5.100.378 | Uh oh... | Continuously firing tears for three seconds causes Isaac to drop a Butt Bomb, which damages and confuses all enemies in the room when it explodes. | 2 | |
Obsessed Fan | 5.100.426 | Follows my every move... | Spawns a familiar that follows Isaac's movements on a delay and deals 30 contact damage per second to enemies. | 0 | |
Papa Fly | 5.100.430 | Turret follower | Spawns a familiar that follows Isaac's movements on a 3 second delay, firing tears at nearby enemies. | 1 | |
Pay To Play | 5.100.380 | Money talks | +5 Coins. Most doors require one Penny to open instead of a Key. +5 Coins. All locked doors, Locked Chests, and Key Blocks must be opened with one Penny instead of Keys. |
2 | |
Pupula Duplex | 5.100.379 | Wide shot | Gives Isaac spectral tears and gives his tears a wide arc shape, increasing their size. | 2 | |
Purity | 5.100.407 | Aura stat boost | Boosts one of Isaac's stats depending on the color of the aura around him. The aura disappears upon taking damage and reappears with a random color upon entering a new room. Red boosts damage, blue boosts tears, yellow boosts speed, and orange boosts range. | 3 | |
Restock | 5.100.376 | Never ending stores! | Causes Shops to instantly restock their items when they are bought. Outside of Greed Mode, the restocked item's cost is increased after each purchase. | 2 | |
Rune Bag | 5.100.389 | Rune generator | Spawns a familiar that drops a random rune after clearing enough rooms. | 3 | |
Sack Head | 5.100.424 | More sacks! | Spawns a Grab Bag on pickup. Coins, Bombs, Keys, cards, runes and batteries have a chance to become Grab Bags. | 3 | |
Scatter Bombs | 5.100.366 | We put bombs in your bombs! | +5 Bombs. Isaac's bombs explode into 2-4 tiny bombs. | 1 | |
Seraphim | 5.100.390 | Sworn friend | Spawns an angel familiar who follows Isaac and fires homing tears which deal 10 damage and have 75% shot speed. | 3 | |
Serpent's Kiss | 5.100.393 | The kiss of death | Tears have a chance to apply a poison effect to enemies. Isaac poisons enemies on contact. Poisoned enemies have a chance to drop a Black Heart when killed. | 2 | |
Spear Of Destiny | 5.100.400 | Your destiny | In addition to tears, Isaac holds a spear in front of him which deals contact damage equal to 2× his tear damage, and occasionally inflicts fear. | 2 | |
Spider Mod | 5.100.403 | Mod buddy! | Displays Isaac's tear damage and enemy health bars. Spawns a familiar that wanders around and inflicts random status effects on enemies it touches. Can spawn a Lil' Battery/Blue spider upon clearing a room. | 1 | |
Sticky Bombs | 5.100.367 | Egg sack bombs! | +5 Bombs. Bombs stick to enemies and spawn 2-4 Blue Spiders if they kill an enemy. They also leave a long-lasting puddle of slowing white creep. | 2 | |
Succubus | 5.100.417 | Damage booster | Spawns a flying familiar that bounces around the room with a black aura, dealing rapid damage to any enemies inside it. While standing in the aura, Isaac gains a 1.5× tear damage multiplier. | 3 | |
Tech X | 5.100.395 | Laser ring tears | Tears are replaced with laser rings that pierce through enemies and deal damage to enemies within them. Can be charged to increase the effectiveness of the ring. | 4 | |
The Wiz | 5.100.358 | Double wiz shot! | Grants spectral tears. Tears simultaneously fire out of both eyes diagonally, similar to the effect of the R U a Wizard? pill. | 0 | |
Toxic Shock | 5.100.350 | Mass poison | Upon entering a room, poisons all enemies, dealing double Isaac's tear damage. Killing enemies leaves a small, short-lasting pool of green creep on the ground. | 3 | |
Tractor Beam | 5.100.397 | Controlled tears | Isaac's tears are bound to a beam emitting in the direction he's firing. +0.5 Tears, +5.25 Range, +0.16 Shot Speed. +1 Fire Rate, +2.5 Range, +0.16 Shot Speed. | 3 | |
Zodiac | 5.100.392 | The heavens will change you | Gives Isaac a random zodiac item effect that changes every floor. | 1 | |
7 Seals | 5.100.526 | Lil harbingers! | Spawns a random Harbinger familiar that changes every 10 seconds. Harbingers have different behaviors and spawn themed Locusts. | 2 | |
Acid Baby | 5.100.491 | Pills pills pills! | Spawns a familiar that drops a random pill every 3 rooms. Upon using a pill, all enemies in the room are poisoned. | 2 | |
Analog Stick | 5.100.465 | 360 tears! | +0.35 tears up. Allows Isaac to fire tears diagonally. | 2 | |
Angelic Prism | 5.100.528 | Eclipsed by the moon | Spawns an orbital familiar with a large orbital radius. Tears that pass through the prism split into four multi-colored tears. | 3 | |
Angry Fly | 5.100.511 | He's violent | Spawns a fly familiar that orbits around a random enemy and deals 30 damage per second to enemies it comes in contact with. | 1 | |
Apple! | 5.100.443 | Trick or treat? | +0.3 tears. Adds a chance to fire a razor blade that deals 4× Isaac's damage. | 3 | |
Backstabber | 5.100.506 | Watch your back! | Isaac's tears deal double damage and inflict bleeding on enemies if they're facing away from Isaac. | 3 | |
Belly Button | 5.100.458 | What's in there? | Drops a random trinket. Grants a second trinket slot. | 2 | |
Big Chubby | 5.100.473 | Chub chub | Spawns a familiar that follows Isaac and charges across the room when Isaac fires, blocking shots and dealing 40.5 damage per second on contact. | 1 | |
Broken Shovel | 5.100.551 | It feels cursed | One of two parts necessary to create Mom's Shovel. No effect if somehow obtained on its own. | 4 | |
Buddy in a Box | 5.100.518 | What could it be?! | Spawns a familiar with a random tear effect. The familiar is randomized at the start of each floor. | 2 | |
Camo Undies | 5.100.497 | Camo kid | Isaac becomes camouflaged at the beginning of each room. Until he shoots, all non-boss enemies will be confused. Isaac gains +0.5 Speed while camouflaged, and gains Tears and Damage upon breaking it. | 3 | |
Compound Fracture | 5.100.453 | Bone tears! | Increases Range. Tears turn into bones, which shatter into 1-3 bone shards upon hitting an enemy or obstacle. | 3 | |
Contagion | 5.100.466 | Outbreak! | The first enemy killed in a room releases a gas cloud that poisons nearby enemies. Affected enemies will also release gas upon death, spreading the effect. | 2 | |
Dad's Lost Coin | 5.100.455 | I remember this... | +1.5 range, +1 tear falling speed. Drops a Lucky Penny. +2.5 range. Drops a Lucky Penny. |
1 | |
Dead Tooth | 5.100.446 | Toxic breath | While firing, Isaac gains a green aura that poisons nearby enemies. | 1 | |
Death's List | 5.100.530 | Just hope you're not next... | Grants a pickup or stat upgrade if all enemies in a room are killed in the order they are marked. | 2 | |
Depression | 5.100.469 | :( | Spawns a familiar that leaves a trail of creep that damages enemies at 6 damage per second. Has a chance to spawn damaging beams of light onto enemies that touch the cloud. | 1 | |
Divorce Papers | 5.100.547 | Tears up + you feel empty | Grants one Bone Heart, +0.7 tears, spawns a Mysterious Paper. | 3 | |
Dog Tooth | 5.100.445 | Bark at the moon! | +0.3 damage, +0.1 speed. Plays a howl or bark sound when entering a room with undiscovered Secret Rooms or Crawl Spaces. | 2 | |
Duality | 5.100.498 | You feel very balanced | Whenever a Devil Room or Angel Room would spawn after defeating a boss, both rooms spawn. Only one can be entered. | 1 | |
Eucharist | 5.100.499 | Peace be with you | An Angel Room will always spawn after every boss fight, excluding the first floor and floors after Chapter 4. | 3 | |
Euthanasia | 5.100.496 | Needle shot | Adds a luck-based chance to fire needles that instantly kill basic enemies and deal triple damage to bosses. If a needle kills an enemy, it bursts into more tears/needles. | 3 | |
Eye of Belial | 5.100.462 | Possessed tears! | Grants piercing tears. After piercing one enemy, tears start homing and deal double damage. | 3 | |
Eye of Greed | 5.100.450 | Gold tears! | Every 20 tears, Isaac loses 1 Penny and shoots an additional gold tear that petrifies enemies and turns them into gold. Any enemy killed while in this state will drop coins. | 2 | |
Fast Bombs | 5.100.517 | Rapid bomb drops | +7 Bombs. Removes the delay between bomb placements, allowing them to be placed rapidly. Bombs will no longer knock each other away. | 1 | |
Finger! | 5.100.467 | Watch where you point that! | Spawns a finger familiar that faces in the same direction as Isaac, rapidly damaging enemies it points at for 10% of Isaac's damage. | 1 | |
Flat Stone | 5.100.540 | Skipping tears | Tears bounce off the floor, creating splashes. Splashes deal 25% of Isaac's tear damage to all enemies in a small area. | 2 | |
Ghost Pepper | 5.100.495 | Flame tears | Gives a chance to shoot fires alongside tears that block enemy shots and deal damage to enemies that touch them. Gives a chance to shoot blue fires alongside tears that become smaller as they travel. |
3 | |
Glaucoma | 5.100.460 | Blind tears! | Adds a chance to shoot tears that confuse enemies for an extremely long time. | 1 | |
Glyph of Balance | 5.100.464 | A gift from above | Grants 2 Soul Hearts and modifies drops from Champion monsters based on certain conditions. Also modifies room clear drops. | 2 | |
Haemolacria | 5.100.531 | I'm seeing red... | Tears are now fired in an arc. Upon hitting the floor, an obstacle, or an enemy, they burst into many smaller tears in all directions. Increases tear delay. | 4 | |
Hushy | 5.100.470 | Lil hush! | Spawns a Hush familiar that bounces diagonally around the room and deals contact damage. While firing tears, it stops moving. | 0 | |
Jacob's Ladder | 5.100.494 | Electric tears | Tears fire sparks of electricity in random directions upon hitting an obstacle or enemy. | 3 | |
Jaw Bone | 5.100.548 | Fetch! | Spawns a familiar that flies through the room while firing, dealing a flat 7 contact damage to enemies and retrieving pickups. | 1 | |
Jumper Cables | 5.100.520 | Bloody recharge | Grants an active item charge every 15 enemies killed. | 3 | |
King Baby | 5.100.472 | Hail to the king baby | Spawns a familiar that follows Isaac and makes other familiars follow it. While firing tears, other familiars stop moving. | 1 | |
Lachryphagy | 5.100.532 | Feed them! | Isaac's tears decelerate as they travel. Upon stopping or hitting an obstacle, they burst into 8 tears in all directions. Tears can be fired into other tears to feed them, increasing their damage. | 2 | |
Large Zit | 5.100.502 | Creep shots | Adds a chance to fire a creep shot that deals double damage and leaves a trail of slowing white creep. | 1 | |
Lead Pencil | 5.100.444 | He's a bleeder! | After every 15 tears fired, Isaac will fire a high-damage cluster of tears. | 3 | |
Lil Delirium | 5.100.519 | Delirious friend | Grants a familiar that transforms into another random familiar every 10 seconds. | 2 | |
Lil Monstro | 5.100.471 | Ain't he cute? | Spawns a familiar that fires clusters of tears. Must be charged before shooting. | 2 | |
Lil Spewer | 5.100.537 | Puking buddy | Drops a random pill, and spawns a familiar that charges up and fires creep. Using pills changes the creep type. | 1 | |
Linger Bean | 5.100.447 | Crying makes me toot | Constantly shooting causes Isaac to release gas clouds that can be pushed by his tears and damage nearby enemies. | 0 | |
Little Horn | 5.100.503 | Big brother is watching | Adds a chance to fire a piercing tear that instantly kills any enemy that it touches. Adds a chance to fire a tear that summons Big Horn's hand to crush the first enemy it hits, instantly killing monsters or greatly damaging bosses. |
3 | |
Parasitoid | 5.100.461 | Egg tears! | Adds a chance to fire an egg sack which creates slowing creep and spawns a Blue Fly or Blue Spider upon hitting an enemy. | 3 | |
Pointy Rib | 5.100.544 | Stabbing time | Spawns a bone familiar that hovers back and forth in front of Isaac, dealing damage equal to Isaac's damage. | 2 | |
Poke Go | 5.100.505 | Gotta catch em... | Upon entering a room with enemies in it, has a chance to spawn a random friendly enemy that persists across rooms. | 2 | |
Polydactyly | 5.100.454 | Hold me! | Allows Isaac to carry two cards, pills, or any combination of both. Spawns one random card, rune, or pill. | 2 | |
Pop! | 5.100.529 | Eyeball tears! | Replaces Isaac's tears with eyeballs that can bounce off of each other. The eyeballs are not limited by range, and will instead dissipate when they stop moving or when hitting an enemy or obstacle. | 1 | |
Sack of Sacks | 5.100.500 | Gives sacks | Spawns a familiar that drops a Grab Bag every 5-6 rooms cleared. | 3 | |
Schoolbag | 5.100.534 | Extra active item room | Allows Isaac to hold two active items. | 3 | |
Shade | 5.100.468 | It follows | Spawns a shadow familiar that follows Isaac's movements on a 1 second delay and deals contact damage to enemies. After dealing enough damage, it is absorbed by Isaac and spawns friendly Chargers. | 0 | |
Sinus Infection | 5.100.459 | Booger tears! | Adds a chance to fire a booger that sticks to enemies and deals damage over time. | 3 | |
Sulfuric Acid | 5.100.463 | Acid tears! | +0.3 damage. Adds a chance to fire acidic tears which can destroy obstacles and open doors. | 2 | |
Tarot Cloth | 5.100.451 | I see the future | Drops a random card or rune. Doubles the effects of most cards and runes. Doubles the effects of tarot cards. | 2 | |
Technology Zero | 5.100.524 | Static tears! | Connects Isaac's tears with electricity that can damage enemies. | 3 | |
Trisagion | 5.100.533 | Smite thy enemy | Tears are replaced with piercing white blasts of light that deal less damage but can damage the same enemy multiple times. | 3 | |
YO LISTEN! | 5.100.492 | Yo listen! | +1 luck. Spawns a fairy familiar that points out Secret Rooms, Crawl Space entrances, and tinted rocks. | 2 | |
120 Volt | 5.100.559 | Zap! | Repeatedly zaps enemies that are close to Isaac. | 2 | |
4.5 Volt | 5.100.647 | Beat the juice out of them! | Active items don't charge when clearing rooms. Instead, they're charged by dealing damage to enemies. | 2 | |
A Bar of Soap | 5.100.564 | Tears + shot speed up | +0.5 Tears, +0.2 Shot Speed. | 3 | |
Act of Contrition | 5.100.601 | Tears up, you feel forgiven | +0.7 tears, grants an Eternal Heart. Allows Angel Rooms to appear even if a Devil Deal has been taken before. Reduces the Devil/Angel room chance penalty for taking Red heart damage. | 3 | |
Akeldama | 5.100.641 | Spill your guts | While in an uncleared room, Isaac forms a trail of bloody tears that drags behind him, bursting and dealing damage upon contact with enemies. | 2 | |
Almond Milk | 5.100.561 | DMG down + tears up + you feel nutty | Quadruples fire rate, with ×0.3 damage multiplier. Each tear is a given random effect that alters its movement. | 1 | |
Azazel's Rage | 5.100.699 | Ancient power | Isaac builds rage every time a room is cleared. After four rooms, fires a large Brimstone laser when entering the next room. | 2 | |
Battery Pack | 5.100.603 | Instant energy! | Recharges Isaac's currently held active item and drops 2-4 batteries. | 0 | |
Bird's Eye | 5.100.616 | It burns | Gives a chance to shoot fires alongside tears that block enemy shots and deal damage to enemies that touch them. | 3 | |
Birthright | 5.100.619 | ??? | Grants a character-specific effect that enhances their special abilities. | 3 | |
Blood Puppy | 5.100.565 | What a cute little thing! | Spawns a familiar that chases enemies. After killing enough enemies, it becomes more powerful but will also try to hurt Isaac. Dealing enough damage to it returns it to normal. | 1 | |
Boiled Baby | 5.100.607 | Messy friend | Gives Isaac a familiar that fires chaotic bursts of tears in all directions. | 1 | |
Bone Spurs | 5.100.683 | Break your enemies | Enemies spawn floating bones on death, which block shots and damage/repel enemies that touch them. | 2 | |
Booster Pack | 5.100.624 | Collect them all! | Drops 5 random cards. | 1 | |
Brimstone Bombs | 5.100.646 | Demon blast +5 bombs | +5 Bombs. Bombs fire four Brimstone lasers in the cardinal directions upon exploding. | 2 | |
C Section | 5.100.678 | Fetus shots | Replaces tears with fetuses that chase down enemies and deal contact damage. Each shot requires a brief charge up. | 4 | |
Card Reading | 5.100.660 | A link to your future | Spawns two portals at the beginning of each floor that each lead to either the Boss Room, Treasure Room, or Secret Room. | 3 | |
Consolation Prize | 5.100.644 | +1 to lowest stat | Increases Isaac's lowest stat and drops either 3 Coins, 1 Bomb, or 1 Key depending on what Isaac has the least of. | 1 | |
Dirty Mind | 5.100.576 | Filthy friends | Destroying poop spawns Dip Familiars that follow Isaac and damage enemies. Destroying different types of poop spawns different Dips with special effects. | 1 | |
Dream Catcher | 5.100.566 | Sweet dreams | During the transition between floors, Isaac's nightmare shows the contents of the upcoming floor's Treasure Room, as well as the floor's boss. Grants a Half Soul Heart when entering a new floor. | 2 | |
Echo Chamber | 5.100.700 | I can see see the future future future | When Isaac uses a Card, Pill, or Rune, he also uses a copy of the previous three Cards/Pills/Runes he used after picking up Echo Chamber. | 3 | |
Evil Charm | 5.100.632 | Luck up + you feel protected | +2 luck. Provides immunity to burn, confusion, fear, and poison. | 2 | |
Eye Drops | 5.100.600 | Tears up | Increases the fire rate in Isaac's left eye, causing his eyes to fire at different rates. | 3 | |
Eye of the Occult | 5.100.572 | DMG up + range up + controlled tears | +1 damage, +2 range, -0.16 shot speed. Isaac's tears can be controlled mid-flight with tear controls. | 3 | |
Eye Sore | 5.100.558 | More eyes | Causes Isaac to occasionally fire extra tears in random directions while shooting. | 1 | |
False PHD | 5.100.654 | Worse pills + evil up | Converts good pills into bad pills and identifies all pills. Bad pills now have secondary positive effects. Grants one Black Heart. | 2 | |
Freezer Baby | 5.100.608 | Iced iced baby | Spawns a shooting familiar that has a chance to petrify enemies, and freezes monsters upon killing them. | 2 | |
Fruity Plum | 5.100.649 | Bouncy friend | Gives Isaac a miniature Baby Plum familiar that propels itself diagonally around the room, firing tears behind itself as it travels. | 1 | |
Ghost Bombs | 5.100.727 | Spooky blast +5 bombs | +5 Bombs. Bombs become spectral and spawn ghosts that deal contact damage to enemies and explode after 10 seconds. | 2 | |
Glass Eye | 5.100.730 | DMG + luck up | +0.75 damage, +1 luck. | 3 | |
Glitched Crown | 5.100.689 | ????? | Item pedestals cycle between 5 random items before being picked up. | 4 | |
Guppy's Eye | 5.100.665 | An eye for secrets | Shows the contents of Chests, Fire Places, Grab Bags, and Shopkeepers before they're opened/destroyed. | 2 | |
Hemoptysis | 5.100.726 | Double tap sneeze | Double-tapping a fire button causes Isaac to sneeze blood, dealing damage to enemies in front of him. Affected enemies are cursed and take more damage from Brimstone-like attacks. | 1 | |
Hungry Soul | 5.100.684 | Out for blood | Enemies have a chance to spawn ghosts on death, which chase and deal contact damage to enemies and explode after a short time. | 2 | |
IBS | 5.100.725 | Your stomach rumbles | Causes Isaac to throw poop, create buffing creep, or drop bombs while fighting enemies. | 0 | |
Immaculate Heart | 5.100.573 | Halo of tears | Adds one Red Heart Container and fully restores health. x1.2 damage multiplier. Isaac will occasionally fire extra tears that orbit around him. | 3 | |
Isaac's Tomb | 5.100.701 | Buried memories | Spawns an Old Chest at the start of each floor. | 3 | |
Jupiter | 5.100.594 | You're a gas giant! | +2 red Heart containers, -0.3 speed. Isaac builds speed while standing still, and releases poison gas clouds when he moves afterwards. | 2 | |
Keeper's Kin | 5.100.717 | Under a rock | Rocks and other Obstacles spawn blue spiders over time while in a room with enemies, and spawn two blue spiders when destroyed. | 2 | |
Keeper's Sack | 5.100.716 | Spending power | Gives range, speed, or damage when buying things from a shop. Spawns three coins and a Key on pickup. | 3 | |
Knockout Drops | 5.100.637 | They pack a punch! | Adds a chance to shoot a fist tear that has extremely high knockback and confuses enemies. | 3 | |
Lil Abaddon | 5.100.679 | Abyssal friend | Spawns a familiar that charges a miniature Maw Of The Void attack while Isaac shoots. | 2 | |
Lil Portal | 5.100.681 | It hungers | A familiar that flies forward, consuming pickups in its path. Each one will increase its size and damage and spawn a Blue Fly. Every four pickups, it opens a portal that leads to an unexplored room. | 1 | |
Lodestone | 5.100.617 | Magnetizing tears | Gives Isaac the chance to fire tears that magnetize enemies they hit, causing them to attract nearby pickups and enemies, as well as tears/shots from all sources. | 3 | |
Luna | 5.100.589 | The moon's blessing shines upon you | Adds an extra Secret Room and Super Secret Room to each floor. Secret Rooms contain a beam of light that increases Fire Rate for the current floor and gives a Half Soul Heart. | 2 | |
Mars | 5.100.593 | Double tap dash | Dash by double-tapping the movement key, becoming invulnerable and damaging enemies. There's a short cooldown before Isaac can dash again. | 2 | |
Member Card | 5.100.602 | Exclusive access! | Adds a trapdoor to every Shop that leads to a second shop with a unique stock and marked-up prices. | 2 | |
Mercurius | 5.100.590 | Speed up + you feel elusive | +0.4 speed. Doors stay open after entering a room, even in rooms with enemies. | 3 | |
Mom's Ring | 5.100.732 | DMG up | +1 Damage. Drops a random Rune or Soul Stone upon pickup. | 3 | |
Monstrance | 5.100.574 | Purifying light | Isaac gains an aura that deals damage to enemies inside it. | 2 | |
Montezuma's Revenge | 5.100.680 | Oh no... | While firing, Isaac charges up a short-ranged Brimstone-like diarrhea beam that shoots behind him. | 2 | |
Mucormycosis | 5.100.553 | Spore shot | Gives Isaac the chance to fire spore tears that stick to enemies and blow up after a few seconds, dealing damage and poisoning nearby enemies and releasing more spores. | 3 | |
Nancy Bombs | 5.100.563 | Random blast +5 bombs | +5 Bombs. Each bomb gains 1-4 random bomb synergies. | 2 | |
Neptunus | 5.100.597 | Open the floodgates | Isaac's mouth fills with tears over time while not firing, up to a cap. Holding the fire button will release all stored tears in rapid succession. | 3 | |
Ocular Rift | 5.100.606 | Stare into the abyss | Adds a chance to fire tears that create rifts where they land, which suck enemies, pickups, and shots towards them and damage enemies in the area. | 3 | |
Options? | 5.100.670 | There might be options | If a room gives a reward when cleared, there will be two different rewards to chose from. Taking one causes the other to disappear. | 2 | |
Paschal Candle | 5.100.567 | Keep the flame burning | Gives Isaac a familiar that grants +0.4 Fire Rate for each consecutive room he's cleared without taking damage. The bonus stacks up to five times. | 3 | |
Playdough Cookie | 5.100.570 | Tasty rainbow | Grants multicolored tears. Each color comes with a different status or tear effect. | 2 | |
Pluto | 5.100.598 | Size down | +0.7 tears. Significantly shrinks Isaac, allowing him to squeeze between objects and makes some enemy shots pass over him. | 3 | |
Purgatory | 5.100.634 | Help from beyond | While in a room with enemies, spawns red cracks in the ground. Walking over these cracks summons ghosts that launch themselves at enemies and explode. | 2 | |
Quints | 5.100.661 | They lurk inside | The first five enemies killed in a room will spawn stationary shooting familiars where they died. | 2 | |
Red Stew | 5.100.621 | Full HP + temporary DMG up | Refills all heart containers. Grants an enormous damage boost that wears off over time. | 2 | |
Redemption | 5.100.673 | Deliver me from evil | If Isaac enters a Devil Room but leaves without taking/opening anything in it, he gets +1 Damage and a Soul Heart at the start of the next floor. | 2 | |
Revelation | 5.100.643 | Awaken your faith | Grants flight and two Soul Hearts. In addition to tears, Isaac can charge up and fire a powerful holy laser. | 4 | |
Rock Bottom | 5.100.562 | It's only up from there | Locks Isaac's attributes to their highest values reached. | 3 | |
Rocket in a Jar | 5.100.583 | Rocket propulsion +5 bombs | +5 Bombs. If Isaac is currently firing, placing a bomb will instead shoot a fast-moving, explosive rocket in the direction he's facing. | 2 | |
Rotten Tomato | 5.100.618 | Delicious! | Adds a chance to fire tears that mark enemies with the Bait status effect. Enemies marked as bait are attacked by other enemies. | 2 | |
Sacred Orb | 5.100.691 | Destined for greatness | Prevents items of quality 0-1 from appearing, and items of quality 2 from appearing 33% of the time. Quest items are unaffected. | 4 | |
Salvation | 5.100.696 | Divine protection | Gives Isaac a halo that summons beams of light on enemies inside it. The halo grows larger the more times Isaac has taken damage this floor. | 3 | |
Saturnus | 5.100.595 | Ring of tears | Upon entering a room, a circle of tears orbits Isaac. Enemy tears have a chance to be caught in orbit, turning them friendly. | 2 | |
Sausage | 5.100.669 | All stats up | Adds a Red Heart Container, fully heals Isaac, and gives +0.2 Speed, +0.5 Damage, +0.5 Tears, +2.5 Range, +0.2 Shot Speed, and +1.0 Luck. Increases the chance of encountering a Devil Room, Angel Room, and/or Planetarium each by 6.9%. | 3 | |
Sol | 5.100.588 | Radiant victory | Reveals the location of the Boss Room. Upon defeating a boss, activates XIX - The Sun, fully recharges Isaac's active item, grants bonus damage and luck for the rest of the floor, and removes curses. | 2 | |
Soul Locket | 5.100.686 | Power of faith | Gives Isaac a permanent stat boost whenever he picks up a Soul Heart. | 1 | |
Spirit Sword | 5.100.579 | Divine blade | Instead of tears, Isaac swings a sword. Charging does a spin attack and fires a projectile, and a projectile is sometimes fired with normal swings if Isaac has no empty Red Heart Containers. | 3 | |
Stapler | 5.100.708 | DMG up | +1 Damage. Prevents Isaac from firing tears from his left eye, like Cain. | 3 | |
Star of Bethlehem | 5.100.651 | Follow the light | Spawns a star familiar that slowly travels towards the Boss Room, giving an aura that increases damage and tears and grants homing tears. | 3 | |
Strawman | 5.100.667 | A helping hand | Spawns a controllable Keeper to fight enemies alongside Isaac, functioning similarly to Jacob and Esau. If Keeper dies, he spawns 5 blue spiders and Strawman is removed from Isaac's inventory. | 2 | |
Stye | 5.100.731 | DMG + range up | Tears fired from Isaac's right eye have +28% Damage, +6.5 Range, and -0.3 Shot Speed. | 2 | |
Terra | 5.100.592 | Born to rock | +1 Damage. Replaces tears with rocks that deal variable damage, have increased knockback, and can destroy obstacles. | 3 | |
The Intruder | 5.100.575 | Invasive friend | A familiar burrows in Isaac's head, firing 4 slowing tears. Upon taking damage, there's a chance it will burst out of Isaac's head, spawning blue spiders and chasing enemies for the current room. | 3 | |
The Stairway | 5.100.586 | May you get what you came for | Generates a ladder at the start of every floor that leads to a unique Angel Room shop. | 3 | |
TMTRAINER | 5.100.721 | ZZaZZ ZZdZZiZZmZZhZZ ZZvZZ ZZoZZ ZZ ZZsZZlZZhZZsZZoZZaZZiZZ | Causes all future items to be "glitched", granting them completely random effects. | 0 | |
Tooth and Nail | 5.100.663 | You feel prickly | Isaac periodically turns into a spiked statue, briefly becoming invulnerable and dealing contact damage. | 2 | |
Tropicamide | 5.100.659 | Tear size + range up | +2.5 Range, Increases tear size. | 1 | |
Twisted Pair | 5.100.698 | Double trouble! | Spawns two familiars that float on either side of Isaac and fire tears that use his tears, range, shot speed, and tear effects, and scale with damage. | 4 | |
Uranus | 5.100.596 | Ice tears | Isaac shoots ice tears, which slow enemies and freeze monsters they kill. Frozen enemies slide away and explode into ice shards when touched. | 3 | |
Vanishing Twin | 5.100.697 | He wants revenge | Spawns a familiar that becomes a weaker clone of the floor's boss when entering the Boss Room. Defeating it drops an extra item. | 2 | |
Vasculitis | 5.100.657 | Clogged enemies | Enemies explode into tears upon death, which inherit the effects of Isaac's tears. | 1 | |
Venus | 5.100.591 | HP up + you feel pretty | Adds one red Heart container. Heals 1 additional Red Heart. Enemies near Isaac become charmed. | 2 | |
Voodoo Head | 5.100.599 | Extra curse rooms | Spawns an additional Curse Room on each floor. Curse Rooms have improved layouts. | 2 | |
Worm Friend | 5.100.682 | Clingy buddy | Gives Isaac a Nerve Ending familiar that burrows out of the ground to grab and deal damage to enemies over time. | 3 |
The Binding of Isaac: Rebirth |
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