Achievements

For tips and strategies on completing achievements, see achievement tips.

Achievements are unlocked after completing Challenges, reaching certain milestones, achieving hidden goals, or unlocking certain items. In the PC version, every Steam achievement exactly corresponds to one secret in-game, whereas only a handful of secrets are represented by PSN trophies in the PlayStation version of the game.

If Isaac is unable to unlock achievements, a small icon of a crossed-out trophy will be displayed below the Key's counter. Conditions which can disable the ability to unlock achievements include:

• Using a pre-determined seed. Certain cosmetic and difficulty-increasing special seeds will still allow unlocks.
• During a Challenge, although the achievement for completing the challenge is unaffected.
• During a Daily Challenge, although the achievements associated with this game mode are unaffected.
• Playing with any enabled mod (unless Mom has been beaten).
• During Victory Laps.
• If the Debug Console is enabled (unless Mom has been beaten).

Rebirth has a total of 178 unlockable secrets. Afterbirth added 98 new secrets, for a total of 276. Afterbirth † added 63 new secrets, for a total of 339. Booster Pack #5 added 64 new secrets, for a total of 403. Repentance added 234 new secrets, for a total of 637. Repentance+ added 3 new secrets, for a total of 640.

Inside the stats menu, while having the "secrets" menu open, pressing Alt + F2 will sync unlocks with Steam achievements. If you have Steam achievements for secrets that haven't been unlocked in-game, they will be unlocked by doing this. NOTE: using this on a second file will take your first file and copy it (because Steam achievements don't consider the file you have unlocked it in).

All Achievements

Name	ID	Icon	Description	Unlock
Magdalene	1		Unlocked a new character.	Have 7 or more Red Heart Containers at one time
Cain	2		Unlocked a new character.	Hold 55 Coins at one time
Judas	3		Unlocked a new character.	Defeat Satan
The Womb	4		Chapter 4 - The Womb unlocked.	Defeat Mom
The Harbingers	5		The horsemen are loose.	Defeat Mom
A Cube of Meat	6		Unlocked a new item. (Also unlocks the Ball of Bandages)	Defeat Mom
The Book of Revelations	7		Unlocked a new item.	Defeat a Harbinger
A Noose	8		Unlocked a new item.	Defeat Mom's Heart 3 times
The Nail	9		Unlocked a new item.	Complete the Boss Rush as Azazel
A Quarter	10		Unlocked a new item.	Defeat Mom's Heart 8 times
A Fetus in a Jar	11		Unlocked a new item.	Defeat Mom's Heart 9 times
A Small Rock	12		Unlocked a new item.	Destroy 100 Tinted Rocks
Monstro's Tooth	13		Unlocked a new item.	Beat Chapter 1
Lil' Chubby	14		Unlocked a new item.	Beat Chapter 2
Loki's Horns	15		Unlocked a new item.	Defeat Lokii
Something From The Future	16		New boss in the basement!	Beat Basement 40 times
Something Cute	17		New boss in the caves!	Beat Chapter 2 30 times
Something Sticky	18		New boss in the depths!	Beat Chapter 3 20 times
A Bandage	19		Unlocked a new item.	Make a Super Bandage Girl by picking up 4 copies of Ball of Bandages in one run; see Unlocking Super Meat Boy & Super Bandage Girl
A Cross	20		Unlocked a new item.	Defeat Isaac as Magdalene
A Bag of Pennies	21		Unlocked a new item.	Defeat Isaac as Cain
The Book of Sin	22		Unlocked a new item.	Defeat all 7 Deadly Sins
Little Gish	23		Unlocked a new item.	Defeat Gish
Little Steven	24		Unlocked a new item.	Defeat Steven
Little C.H.A.D.	25		Unlocked a new item.	Defeat C.H.A.D.
A Gamekid	26		Unlocked a new item.	Visit 10 Arcades
A Halo	27		Unlocked a new item.	Defeat Mom, Mom's Heart, or It Lives! using The Bible or XV - The Devil?
Mr. Mega	28		Unlocked a new item.	Destroy 10 Tinted Rocks
The D6	29		Isaac now holds the D6!	Defeat Isaac as ???
The Scissors	30		Unlocked a new item.	Die 100 times
The Parasite	31		Unlocked a new item.	Pick up any 2 of the following items in a single run: Bob's Rotten Head, Dead Cat, Cricket's Head, and Tammy's Head ( Any 2 items that have the 'dead' item tag)
???	32		Unlocked a new character.	Defeat Mom's Heart 10 times
Everything Is Terrible!!!	33		The game just got harder!	Defeat Mom's Heart 5 times
It Lives!	34		Your future's past waits.	Defeat Mom's Heart 11 times
Mom's Contact	35		Unlocked a new item.	Obtain three Yes Mother? items in one run
The Necronomicon	36		Unlocked a new item.	Use XIII - Death 4 times
Basement Boy	37		Beat basement without taking damage.	Beat Chapter 1 without taking damage
Spelunker Boy	38		Beat caves without taking damage.	Beat Chapter 2 without taking damage
Dark Boy	39		Beat depths without taking damage.	Beat Chapter 3 without taking damage
Mama's Boy	40		Beat womb without taking damage.	Beat Chapter 4 without taking damage
Golden God!	41		You are the best!!	Defeat ??? and The Lamb
Eve	42		Unlocked a new character.	Don't pick up any hearts for 2 floors in a row
Mom's Knife	43		Unlocked a new item.	Defeat Satan as Isaac
The Razor	44		Unlocked a new item.	Defeat Satan as Eve
Guardian Angel	45		Unlocked a new item.	Defeat Satan as Magdalene
A Bag of Bombs	46		Unlocked a new item.	Defeat Satan as Cain
Demon Baby	47		Unlocked a new item.	Defeat The Lamb as Azazel
Forget Me Now	48		Unlocked a new item.	Defeat Satan as ???
The D20	49		Unlocked a new item.	Defeat ??? as Isaac
Celtic Cross	50		Unlocked a new item.	Defeat ??? as Magdalene
Abel	51		Unlocked a new item.	Defeat The Lamb as Cain
Curved Horn	52		Unlocked a new item.	Defeat The Lamb as Judas
Sacrificial Dagger	53		Unlocked a new item.	Defeat ??? as Eve
Bloody Lust	54		Unlocked a new item.	Defeat Isaac as Samson
Blood Penny	55		Unlocked a new item.	Defeat ??? as Samson
Blood Rights	56		Unlocked a new item.	Defeat Satan as Samson
The Polaroid	57		Unlocked a new item.	Defeat Isaac 5 times
Dad's Key	58		Unlocked a new item.	Pick up both Key Pieces from the Angels in one run
Blue Candle	59		Unlocked a new item.	Donate 900 coins to the Donation Machine
Burnt Penny	60		Unlocked a new item.	Complete Beans! (challenge #13)
Lucky Toe	61		Unlocked a new item.	Blow up 20 Shopkeepers
Epic Fetus	62		Unlocked a new item.	Complete The Family Man (challenge #19)
SMB Super Fan	63		Unlocked a new item.	Complete It's in the Cards (challenge #14)
Counterfeit Coin	64		Unlocked a new item.	Play either Shell Game or Hell Game 100 times
Guppy's Hairball	65		Unlocked a new item.	Become Guppy
A Forgotten Horseman	66		Unlocked a new boss!	Take 10 Angel Room items
Samson	67		Unlocked a new character.	Complete 2 floors in a row without taking damage
Something Icky	68		New boss in the womb!	Defeat Isaac 10 times
!Platinum God!	69		OMG!	Collect all non-DLC items in the game, and unlock all of the secrets and endings (minus The Lost and his 6 unlockable items)
Isaac's Head	70		Unlocked a new item.	Complete the Boss Rush as Isaac
Maggy's Faith	71		Unlocked a new item.	Defeat The Lamb as Magdalene
Judas' Tongue	72		Unlocked a new item.	Defeat Satan as Judas
???'s Soul	73		Unlocked a new item.	Defeat The Lamb as ???
Samson's Lock	74		Unlocked a new item.	Defeat The Lamb as Samson
Cain's Eye	75		Unlocked a new item.	Defeat ??? as Cain
Eve's Bird Foot	76		Unlocked a new item.	Defeat Isaac as Eve
The Left Hand	77		Unlocked a new item.	Defeat Ultra Pride as any character, or ??? as Judas
The Negative	78		Unlocked a new item.	Defeat Satan 5 times
Azazel	79		Unlocked a new character.	Make 3 Deals with the Devil in one run
Lazarus	80		Unlocked a new character.	Have 4 or more Soul Hearts at one time
Eden	81		Unlocked a new character.	Complete Chapter 4
The Lost	82		Unlocked a new character.	It's complicated Die in a Sacrifice Room while holding Missing Poster
Dead Boy	83		Beat Chest or Dark Room without taking damage.	Complete Chapter 6 without taking damage
The Real Platinum God	84		111% now stop playing!	Collect every non-DLC item, and unlock every secret and ending.
Lucky Rock	85		Destroy 100 rocks.	Destroy 100 rocks
The Cellar	86		Alt stage to the basement.	Beat all Basement bosses ( except Baby Plum) (not restricted to beating bosses in The Basement)
The Catacombs	87		Alt stage to the caves.	Beat all Caves bosses ( except Bumbino) (not restricted to beating bosses in The Caves)
The Necropolis	88		Alt stage to the depths.	Beat all Depths bosses ( except Reap Creep) (not restricted to beating bosses in The Depths)
Rune of Hagalaz	89		Unlocked a new item.	Complete Pitch Black (challenge #1)
Rune of Jera	90		Unlocked a new item.	Complete High Brow (challenge #2)
Rune of Ehwaz	91		Unlocked a new item.	Complete Head Trauma (challenge #3)
Rune of Dagaz	92		Unlocked a new item.	Complete Darkness Falls (challenge #4)
Rune of Ansuz	93		Unlocked a new item.	Complete The Tank (challenge #5)
Rune of Perthro	94		Unlocked a new item.	Complete Solar System (challenge #6)
Rune of Berkano	95		Unlocked a new item.	Complete Purist (challenge #20)
Rune of Algiz	96		Unlocked a new item.	Complete Cat Got Your Tongue (challenge #8)
Chaos Card	97		Unlocked a new item.	Complete Demo Man (challenge #9)
Credit Card	98		Unlocked a new item.	Complete Cursed! (challenge #10)
Rules Card	99		Unlocked a new item.	Complete Glass Cannon (challenge #11)
Card Against Humanity	100		Unlocked a new item.	Complete When Life Gives You Lemons (challenge #12)
Swallowed Penny	101		Unlocked a new item.	Complete Slow Roll (challenge #15)
Robo-Baby 2.0	102		Unlocked a new item.	Complete Computer Savvy (challenge #16)
Death's Touch	103		Unlocked a new item.	Complete Waka Waka (challenge #17)
Technology .5	104		Unlocked a new item.	Complete The Host (challenge #18)
Missing No.	105		Unlocked a new item.	Complete the Boss Rush as Lazarus
Isaac's Tears	106		Unlocked a new item.	Defeat Isaac as Isaac
Guillotine	107		Unlocked a new item.	Defeat Isaac as Judas
Judas' Shadow	108		Unlocked a new item.	Complete the Boss Rush as Judas
Maggy's Bow	109		Unlocked a new item.	Complete the Boss Rush as Magdalene
Cain's Other Eye	110		Unlocked a new item.	Complete the Boss Rush as Cain
Black Lipstick	111		Unlocked a new item.	Defeat The Lamb as Eve
Eve's Mascara	112		Unlocked a new item.	Complete the Boss Rush as Eve
Fate	113		Unlocked a new item.	Defeat ??? as ???
???'s Only Friend	114		Unlocked a new item.	Complete the Boss Rush as ???
Samson's Chains	115		Unlocked a new item.	Complete the Boss Rush as Samson
Lazarus' Rags	116		Unlocked a new item.	Defeat Isaac as Lazarus
Broken Ankh	117		Unlocked a new item.	Defeat Satan as Lazarus
Store Credit	118		Unlocked a new item.	Defeat ??? as Lazarus
Pandora's Box	119		Unlocked a new item.	Defeat The Lamb as Lazarus
Suicide King	120		Unlocked a new item.	Complete Suicide King (challenge #7)
Blank Card	121		Unlocked a new item.	Defeat Isaac as Eden
Book of Secrets	122		Unlocked a new item.	Defeat Satan as Eden
Mysterious Paper	123		Unlocked a new item.	Defeat ??? as Eden
Mystery Sack	124		Unlocked a new item.	Defeat The Lamb as Eden
Undefined	125		Unlocked a new item.	Complete the Boss Rush as Eden
Satanic Bible	126		Unlocked a new item.	Defeat Isaac as Azazel
Daemon's Tail	127		Unlocked a new item.	Defeat Satan as Azazel
Abaddon	128		Unlocked a new item.	Defeat ??? as Azazel
Isaac's Heart	129		Unlocked a new item.	Defeat Isaac as The Lost
The Mind	130		Unlocked a new item.	Defeat Satan as The Lost
The Body	131		Unlocked a new item.	Defeat ??? as The Lost
The Soul	132		Unlocked a new item.	Defeat The Lamb as The Lost
The D100	133		Unlocked a new item.	Complete the Boss Rush as The Lost
Blue Map	134		Unlocked a new item.	Donate 10 Coins to the Donation Machine
There's Options	135		Unlocked a new item.	Donate 50 Coins to the Donation Machine
Black Candle	136		Unlocked a new item	Donate 150 Coins to the Donation Machine
Red Candle	137		Unlocked a new item.	Donate 400 Coins to the Donation Machine
Stop Watch	138		Unlocked a new item	Donate 999 Coins to the Donation Machine
Wire Coat Hanger	139		Unlocked a new item.	Defeat Mom's Heart 4 times
Ipecac	140		Unlocked a new item.	Defeat Mom's Heart 6 times
Experimental Treatment	141		Unlocked a new item.	Defeat Mom's Heart 7 times
Krampus	142		Unlocked another miniboss!	Take 20 items from Devil Rooms
Head of Krampus	143		Unlocked a new item.	Defeat Krampus
Super Meat Boy	144		Built him out of meat cubes.	Make a Super Meat Boy by picking up 4 copies of Cube of Meat in one run; see Unlocking Super Meat Boy & Super Bandage Girl
Butter Bean	145		Unlocked a new item.	Destroy 100 Poops
Little Baggy	146		Unlocked a new item.	Pick up any 2 of the following items in a single run: Roid Rage, The Virus, Growth Hormones, Experimental Treatment, and Speed Ball ( Any 2 items that have the 'syringe' item tag)
Blood Bag	147		Unlocked a new item.	Use the Blood Donation Machine 30 times
The D4	148		Unlocked a new item.	Blow up 30 Slot Machine
Missing Poster	149		Unlocked a new item.	Defeat The Lamb as Isaac
Rubber Cement	150		Unlocked a new item.	Defeat Mom's Heart 2 times
Store Upgrade lv.1	151		Donated 20 pennies to the shop.	Donate 20 Coins to the Donation Machine
Store Upgrade lv.2	152		Donated 100 pennies to the shop.	Donate 100 Coins to the Donation Machine
Store Upgrade lv.3	153		Donated 200 pennies to the shop.	Donate 200 Coins to the Donation Machine
Store Upgrade lv.4	154		Donated 600 pennies to the shop.	Donate 600 Coins to the Donation Machine
Angels	155		They are waiting.	Complete Chapter 6
Godhead	156		Unlocked a new item.	Earn all 6 / 9 / 10 / 12 Completion Marks on Hard mode as The Lost
Darkness Falls	157		Unlocked Challenge #4.	Defeat Mom's Heart 11 times and unlock Eve Defeat Mom's Heart 11 times and defeat ??? as Eve
The Tank	158		Unlocked Challenge #5.	Have 7 or more Red Heart Containers at one time
Solar System	159		Unlocked Challenge #6.	Defeat Mom's Heart 3 times
Suicide King 2	160		Unlocked Challenge #7.	Defeat Mom's Heart 11 times and unlock Lazarus
Cat Got Your Tongue	161		Unlocked Challenge #8.	Become Guppy
Demo Man	162		Unlocked Challenge #9.	Defeat Mom's Heart 9 times
Cursed!	163		Unlocked Challenge #10.	Have 7 or more Red Heart Containers at one time
Glass Cannon	164		Unlocked Challenge #11.	Beat The Family Man (challenge #19), defeat Lokii, and unlock Judas
The Family Man	165		Unlocked Challenge #19.	Pick up both Key Pieces from the Angels in one run
Purist	166		Unlocked Challenge #20.	Defeat Mom
Lost Baby	167		Unlocked a new co-player baby.	Defeat Mom's Heart on Hard mode as Isaac
Cute Baby	168		Unlocked a new co-player baby.	Defeat Mom's Heart on Hard mode as Magdalene
Crow Baby	169		Unlocked a new co-player baby.	Defeat Mom's Heart on Hard mode as Eve
Shadow Baby	170		Unlocked a new co-player baby.	Defeat Mom's Heart on Hard mode as Judas
Glass Baby	171		Unlocked a new co-player baby.	Defeat Mom's Heart on Hard mode as Cain
Wrapped Baby	172		Unlocked a new co-player baby.	Defeat Mom's Heart on Hard mode as Azazel Defeat Mom's Heart on Hard mode as Lazarus
Begotten Baby	173		Unlocked a new co-player baby.	Defeat Mom's Heart on Hard mode as Lazarus Defeat Mom's Heart on Hard mode as Azazel
Dead Baby	174		Unlocked a new co-player baby.	Defeat Mom's Heart on Hard mode as ???
-0- Baby	175		Unlocked a new co-player baby.	Defeat Mom's Heart on Hard mode as The Lost
Glitch Baby	176		Unlocked a new co-player baby.	Defeat Mom's Heart on Hard mode as Eden
Fighting Baby	177		Unlocked a new co-player baby.	Defeat Mom's Heart on Hard mode as Samson
Lord of the Flies	178		You became Lord of the Flies.	Become Beelzebub
Fart Baby	179		Unlocked a new item.	Defeat Hush as Isaac
Purity	180		Unlocked a new item.	Defeat Hush as Magdalene
D12	181		Unlocked a new item.	Defeat Hush as Cain
Betrayal	182		Unlocked a new item.	Defeat Hush as Judas
Fate's Reward	183		Unlocked a new item.	Defeat Hush as ???
Athame	184		Unlocked a new item.	Defeat Hush as Eve
Blind Rage	185		Unlocked a new item.	Defeat Hush as Samson
Maw of the Void	186		Unlocked a new item.	Defeat Hush as Azazel
Empty Vessel	187		Unlocked a new item.	Defeat Hush as Lazarus
Eden's Blessing	188		Unlocked a new item.	Defeat Hush as Eden
Sworn Protector	189		Unlocked a new item.	Defeat Hush as The Lost
Incubus	190		Unlocked a new item.	Defeat Hush as Lilith
Keeper now holds... A Penny!	191		Unlocked a new item.	Defeat Hush as Keeper
Lil' Chest	192		Unlocked a new item.	Defeat Ultra Greed as Isaac
Censer	193		Unlocked a new item.	Defeat Ultra Greed as Magdalene
Evil Eye	194		Unlocked a new item.	Defeat Ultra Greed as Cain
My Shadow	195		Unlocked a new item.	Defeat Ultra Greed as Judas
Cracked Dice	196		Unlocked a new item.	Defeat Ultra Greed as ???
Black Feather	197		Unlocked a new item.	Defeat Ultra Greed as Eve
Lusty Blood	198		Unlocked a new item.	Defeat Ultra Greed as Samson
Lilith	199		Unlocked a new character.	Defeat Ultra Greed as Azazel
Key Bum	200		Unlocked a new item.	Defeat Ultra Greed as Lazarus
GB Bug	201		Unlocked a new item.	Defeat Ultra Greed as Eden
Zodiac	202		Unlocked a new item.	Defeat Ultra Greed as The Lost
Box of Friends	203		Unlocked a new item.	Defeat Ultra Greed as Lilith
Rib of Greed	204		Unlocked a new item.	Defeat Ultra Greed as Keeper
Cry Baby	205		Unlocked a new co-player baby.	Defeat Mega Satan as Isaac
Red Baby	206		Unlocked a new co-player baby.	Defeat Mega Satan as Magdalene
Green Baby	207		Unlocked a new co-player baby.	Defeat Mega Satan as Cain
Brown Baby	208		Unlocked a new co-player baby.	Defeat Mega Satan as Judas
Blue Baby	209		Unlocked a new co-player baby.	Defeat Mega Satan as ???
Lil' Baby	210		Unlocked a new co-player baby.	Defeat Mega Satan as Eve
Rage Baby	211		Unlocked a new co-player baby.	Defeat Mega Satan as Samson
Black Baby	212		Unlocked a new co-player baby.	Defeat Mega Satan as Azazel
Long Baby	213		Unlocked a new co-player baby.	Defeat Mega Satan as Lazarus
Yellow Baby	214		Unlocked a new co-player baby.	Defeat Mega Satan as Eden
White Baby	215		Unlocked a new co-player baby.	Defeat Mega Satan as The Lost
Big Baby	216		Unlocked a new co-player baby.	Defeat Mega Satan as Lilith
Noose Baby	217		Unlocked a new co-player baby.	Defeat Mega Satan as Keeper
Rune Bag	218		Unlocked a new item.	Defeat Isaac as Lilith
Cambion Conception	219		Unlocked a new item.	Defeat ??? as Lilith
Serpent's Kiss	220		Unlocked a new item.	Defeat Satan as Lilith
Succubus	221		Unlocked a new item.	Defeat The Lamb as Lilith
Immaculate Conception	222		Unlocked a new item.	Complete the Boss Rush as Lilith
Goat Head Baby	223		Unlocked a new co-player baby.	Defeat Mom's Heart on Hard mode as Lilith
Gold Heart	224		Unlocked a new item.	Complete XXXXXXXXL (challenge #21)
Get out of Jail Free Card	225		Unlocked a new item.	Complete SPEED! (challenge #22)
Gold Bomb	226		Unlocked a new item.	Complete Blue Bomber (challenge #23)
2 new pills	227		Unlocked a new item.	Complete PAY TO PLAY (challenge #24)
2 new pills 2	228		Unlocked a new item.	Complete Have a Heart (challenge #25)
Poker Chip	229		Unlocked a new item.	Complete I RULE! (challenge #26)
Stud Finder	230		Unlocked a new item.	Complete BRAINS! (challenge #27)
D8	231		Unlocked a new item.	Complete PRIDE DAY! (challenge #28)
Kidney Stone	232		Unlocked a new item.	Complete The Guardian (challenge #30) Complete Onan's Streak (challenge #29)
Blank Rune	233		Unlocked a new item.	Complete Onan's Streak (challenge #29) Complete The Guardian (challenge #30)
Blue Womb	234		Unlocked a hidden chapter.	Defeat Mom's Heart 10 times
1001%	235		Nerd x 1000000	Unlock all Afterbirth secrets and endings, and collect every Afterbirth item / Unlock 275 random achievements and have at least 510 items in the collection page
Keeper holds Wooden Nickel	236		Unlocked a new starting item.	Defeat Isaac as Keeper
Keeper holds Store Key	237		Unlocked a new starting item.	Defeat Satan as Keeper
Deep Pockets	238		Unlocked a new item.	Defeat ??? as Keeper
Karma	239		Unlocked a new item.	Defeat The Lamb as Keeper
Sticky Nickels	240		Unlocked a new item.	Complete the Boss Rush as Keeper
Super Greed Baby	241		Unlocked a new co-player baby.	Defeat Mom's Heart on Hard mode as Keeper
Lucky Pennies	242		Unlocked a new item.	Donate 2 Coins to the Greed Donation Machine
Special Hanging Shopkeepers	243		Unlocked a secret.	Donate 14 Coins to the Greed Donation Machine
Wooden Nickel	244		Unlocked a new item.	Donate 33 Coins to the Greed Donation Machine
Cain holds Paperclip	245		Unlocked a new starting item.	Donate 68 Coins to the Greed Donation Machine
Everything is Terrible 2!!!	246		Greed just got harder!	Donate 111 Coins to the Greed Donation Machine
Special Shopkeepers	247		Unlocked a secret.	Donate 234 Coins to the Greed Donation Machine
Eve now holds Razor Blade	248		Unlocked a new starting item.	Donate 439 Coins to the Greed Donation Machine
Store Key	249		Unlocked a new item.	Donate 666 Coins to the Greed Donation Machine
Lost holds Holy Mantle	250		Unlocked a new starting item.	Donate 879 Coins to the Greed Donation Machine
Keeper	251		Unlocked a new character.	Donate 1000 Coins to the Greed Donation Machine
Hive Baby	252		Unlocked a new co-player baby.	Earn all Hard mode Completion Marks as ???
Buddy Baby	253		Unlocked a new co-player baby.	Earn all Hard mode Completion Marks as Isaac
Colorful Baby	254		Unlocked a new co-player baby.	Earn all Hard mode Completion Marks as Magdalene
Whore Baby	255		Unlocked a new co-player baby.	Earn all Hard mode Completion Marks as Eve
Cracked Baby	256		Unlocked a new co-player baby.	Earn all Hard mode Completion Marks as Eden
Dripping Baby	257		Unlocked a new co-player baby.	Earn all Hard mode Completion Marks as Lazarus
Blinding Baby	258		Unlocked a new co-player baby.	Use Blank Card while holding XIX - The Sun
Sucky Baby	259		Unlocked a new co-player baby.	Earn all Hard mode Completion Marks as Azazel
Dark Baby	260		Unlocked a new co-player baby.	Earn all Hard mode Completion Marks as Lilith
Picky Baby	261		Unlocked a new co-player baby.	Earn all Hard mode Completion Marks as Cain
Revenge Baby	262		Unlocked a new co-player baby.	Earn all Hard mode Completion Marks as Samson
Belial Baby	263		Unlocked a new co-player baby.	Earn all Hard mode Completion Marks as Judas
Sale Baby	264		Unlocked a new co-player baby.	Earn all Hard mode Completion Marks as Keeper
XXXXXXXXL	265		Unlocked Challenge #21.	Defeat Mom
SPEED!	266		Unlocked Challenge #22.	Defeat Mom
Blue Bomber	267		Unlocked Challenge #23.	Destroy 10 Tinted Rocks and defeat Mom's Heart 11 times
PAY TO PLAY	268		Unlocked Challenge #24.	Defeat Isaac as Cain and destroy 10 Tinted Rocks
Have a Heart	269		Unlocked Challenge #25.	Defeat Mom
I RULE!	270		Unlocked Challenge #26.	Defeat ??? or The Lamb, defeat Satan as Isaac, and unlock The Negative Defeat ??? or The Lamb, and defeat Satan as Isaac Defeat Mega Satan and unlock The Negative
BRAINS!	271		Unlocked Challenge #27.	Defeat Isaac 5 times
PRIDE DAY!	272		Unlocked Challenge #28.	Defeat Mom
Onan's Streak	273		Unlocked Challenge #29.	Defeat Mom Unlock Judas and It Lives!
The Guardian	274		Unlocked Challenge #30.	Defeat Mom
Generosity	275		If only everyone was as generous as you are...	Donate 999 Coins to the Greed Donation Machine
Mega	276		Unlocked...	Defeat Mega Satan as every character ( except tainted characters)
Backasswards	277		Unlocked a new challenge.	Defeat ??? or The Lamb Defeat Mega Satan and unlock The Negative
Aprils fool	278		Unlocked a new challenge.	Defeat Mom
Pokey Mans	279		Unlocked a new challenge.	Defeat Mom's Heart 11 times
Ultra Hard	280		Unlocked a new challenge.	Defeat ??? or The Lamb. Possession of The Polaroid / The Negative is required, barring getting to Dark Room through a Sacrifice Room. Defeat Mega Satan and unlock The Negative
PONG	281		Unlocked a new challenge.	Defeat Isaac 5 times
D infinity	282		Unlocked a new item.	Defeat Delirium as Isaac
Eucharist	283		Unlocked a new item.	Defeat Delirium as Magdalene
Silver Dollar	284		Unlocked a new item.	Defeat Delirium as Cain
Shade	285		Unlocked a new item.	Defeat Delirium as Judas
King Baby	286		Unlocked a new co-player baby.	Defeat Delirium as ???
Bloody Crown	287		Unlocked a new item.	Defeat Delirium as Samson
Dull Razor	288		Unlocked a new item.	Defeat Delirium as Eve
Eden's Soul	289		Unlocked a new item.	Defeat Delirium as Eden
Dark Prince's Crown	290		Unlocked a new item.	Defeat Delirium as Azazel
Compound Fracture	291		Unlocked a new item.	Defeat Delirium as Lazarus
Euthanasia	292		Unlocked a new item.	Defeat Delirium as Lilith
Holy Card	293		Unlocked a new item.	Defeat Delirium as The Lost
Crooked Penny	294		Unlocked a new item.	Defeat Delirium as Keeper
Void	295		Unlocked a new item.	Defeat Delirium as Apollyon
D1	296		Unlocked a new item.	Defeat Ultra Greedier as Isaac
Glyph of Balance	297		Unlocked a new item.	Defeat Ultra Greedier as Magdalene
Sack of Sacks	298		Unlocked a new item.	Defeat Ultra Greedier as Cain
Eye of Belial	299		Unlocked a new item.	Defeat Ultra Greedier as Judas
Meconium	300		Unlocked a new item.	Defeat Ultra Greedier as ???
Stem Cell	301		Unlocked a new item.	Defeat Ultra Greedier as Samson
Crow Heart	302		Unlocked a new item.	Defeat Ultra Greedier as Eve
Metronome	303		Unlocked a new item.	Defeat Ultra Greedier as Eden
Bat Wing	304		Unlocked a new item.	Defeat Ultra Greedier as Azazel
Plan C	305		Unlocked a new item.	Defeat Ultra Greedier as Lazarus
Duality	306		Unlocked a new item.	Defeat Ultra Greedier as Lilith
Dad's Lost Coin	307		Unlocked a new item.	Defeat Ultra Greedier as The Lost
Eye of Greed	308		Unlocked a new item.	Defeat Ultra Greedier as Keeper
Black Rune	309		Unlocked a new item.	Defeat Ultra Greedier as Apollyon
Locust of Wrath	310		Unlocked a new item.	Defeat Isaac as Apollyon
Locust of Pestilence	311		Unlocked a new item.	Defeat Satan as Apollyon
Locust of Famine	312		Unlocked a new item.	Defeat ??? as Apollyon
Locust of Death	313		Unlocked a new item.	Defeat The Lamb as Apollyon
Locust of Conquest	314		Unlocked a new item.	Complete the Boss Rush as Apollyon
Hushy	315		Unlocked a new item.	Defeat Hush as Apollyon
Brown Nugget	316		Unlocked a new item.	Defeat Ultra Greed as Apollyon
Mort Baby	317		Unlocked a new co-player baby.	Defeat Mega Satan as Apollyon
Smelter	318		Unlocked a new item.	Defeat Mom's Heart or It Lives! on Hard mode as Apollyon
Apollyon Baby	319		Unlocked a new co-player baby.	Earn all Hard mode Completion Marks as Apollyon
New Area	320		Unlocked a new area.	Defeat Hush
Once More with Feeling!	321		Unlocked a new item.	Complete a Victory Lap by defeating The Lamb
Hat trick!	322		Unlocked a new item.	Get a 3-win streak
5 Nights at Mom's	323		Unlocked super special rocks.	Get a 5-win streak, using a different character each time ( this number can be reduced to 3, see the notes section)
Sin collector	324		Unlocked a new item.	Collect every entry in the Bestiary (bugged v190 - Mobs that don't exist in the bestiary are being counted. This allows Sin Collector to be unlocked without a complete bestiary)
Dedication	325		Unlocked a new item.	Participate in 31 Daily Challenges (they don't have to be consecutive; it will still count if Isaac dies in the first room)
ZIP!	326		Unlocked a new item.	Defeat The Lamb in under 20 minutes
It's the Key	327		Unlocked a new item.	Defeat The Lamb without taking Hearts, Coins, or Bombs through the entire run. Letting certain familiars (e.g. Bum Friend, Dark Bum, Bumbo or Lil Portal) or bosses (e.g. Bumbino) pick up the consumables fails this condition as well.
Mr. Resetter!	328		Unlocked a new item.	Reset 7 times in a row Switch PS4 Get a minus 10-win streak
Living on the edge	329		Unlocked a new item.	Complete a Chapter (floors I and II) after Basement, start-to-finish, with only half a Heart total (can use The Lost)
U Broke It!	330		Unlocked a new item.	Obtain 50 items in a run (duplicate passive items/familiars count towards the total, e.g., multiple Breakfast)
Laz Bleeds More!	331		Unlocked a new starting item.	Complete Backasswards (challenge #31)
Maggy Now Holds a Pill!	332		Unlocked a new starting item.	Complete Aprils Fool (challenge #32)
Charged Key	333		Unlocked a new item.	Complete Pokey Mans (challenge #33)
Samson Feels Healthy!	334		Unlocked a new starting item.	Complete Ultra Hard (challenge #34)
Greed's Gullet	335		Unlocked a new item.	Complete Pong (challenge #35)
The Marathon	336		Unlocked a new item.	Get a 5-win streak in the Daily Challenges (they don't have to be consecutive days, only the runs you play are counted)
RERUN	337		Unlocked the power of RERUN.	Complete 3 Victory Laps by defeating The Lamb
Delirious	338		Unlocked a new item.	Defeat Delirium
1000000%	339		Just Stop!	Collect every item in the game, unlock all secrets and endings, and complete the Bestiary / Unlock 402 random achievements and have at least 510 items in the collection page
Apollyon	340		Unlocked a new character.	Defeat Mega Satan
Greedier!	341		New mode unlocked!	Donate 500 Coins to the Greed Donation Machine
Burning Basement	342		Alt stage to the basement.	Defeat Mom's Heart 11 times
Flooded Caves	343		Alt stage to the caves.	Defeat It Lives! 16 times
Dank Depths	344		Alt stage to the depths.	Defeat It Lives! 21 times
Scarred Womb	345		Alt stage to the womb.	Defeat It Lives! 30 times
Something wicked this way comes!	346		Unlocked new bosses!	Defeat ??? as 3 different Characters
Something wicked this way comes+!	347		Unlocked even more bosses!	Defeat ??? as 6 different Characters
The gate is open!	348		Unlocked new enemies!	Defeat The Lamb
Black Hole	349		Unlocked a new item.	Defeat 20 Portals
Mystery Gift	350		Unlocked a new item.	Destroy 500 rocks
Sprinkler	351		Unlocked a new item.	Beat Chapter 1 without taking damage
Angry Fly	352		Unlocked a new item.	Become Beelzebub
Bozo	353		Unlocked a new item.	Destroy 5 rainbow poops
Broken Modem	354		Unlocked a new item.	Complete 7 Daily Challenges (by touching the trophy at the end)
Buddy in a Box	355		Unlocked a new item.	Pick up 5 familiars in a single run
Fast Bombs	356		Unlocked a new item.	Defeat Little Horn 20 times
Lil Delirium	357		Unlocked a new item.	Defeat Delirium for the 1st time
Hairpin	358		Unlocked a new item.	Recharge using Lil' Batteries 20 times
Wooden Cross	359		Unlocked a new item.	Sleep in a bed
Butter!	360		Unlocked a new item.	Complete 2 Victory Laps by defeating The Lamb
Huge Growth	361		Unlocked a new item.	Be 3 times larger than the starting size. Depending on the item/card/pill size's multiplier, 5 to 7 size increases will be required.
Ancient Recall	362		Unlocked a new item.	Use Cards and Runes 20 times
Era Walk	363		Unlocked a new item.	Add both the Broken Watch and the Stop Watch to your collection
Coupon	364		Unlocked a new item.	Purchase anything from Shops, Devil Rooms, and/or Black Markets 50 times
Telekinesis	365		Unlocked a new item.	Beat Chapter 2 without taking damage
Moving Box	366		Unlocked a new item.	Use Pandora's Box in Dark Room
Jumper Cables	367		Unlocked a new item.	Pick up any 2 of the following items/trinkets in a single run: 9 Volt, The Battery, Car Battery, AAA Battery, and Watch Battery ( Any 2 items that have the 'battery' item tag)
Leprosy	368		Unlocked a new item.	Beat Chapter 3 without taking damage
Technology Zero	369		Unlocked a new item.	Pick up any 2 technology items in a single run ( Any 2 items that have the 'tech' item tag)
Filigree Feather	370		Unlocked a new item.	Acquire both Key Piece 1 and Key Piece 2
Mr. ME!	371		Unlocked a new item.	Open 20 Locked Chests
7 Seals	372		Unlocked a new item.	Defeat all 5 Harbingers
Angelic Prism	373		Unlocked a new item.	Defeat an Angel 10 times
Pop!	374		Unlocked a new item.	Beat Chapter 4 without taking damage
Door Stop	375		Unlocked a new item.	Blow up doors and Secret Room walls 50 times
Death's List	376		Unlocked a new item.	Take 25 Deals with the Devil
Haemolacria	377		Unlocked a new item.	Acquire Blood Clot 10 times
Lachryphagy	378		Unlocked a new item.	Collect 10 "Tears Up" items or pills in one run
Schoolbag	379		Unlocked a new item.	Enter 6 Shops in one run
Trisagion	380		Unlocked a new item.	Take 25 Angel Rooms items
Extension Cord	381		Unlocked a new item.	Have The Battery, 9 Volt, and Car Battery in Isaac's collection
Flat Stone	382		Unlocked a new item.	Acquire Rubber Cement 5 times
Sacrificial Altar	383		Unlocked a new item.	Take 50 Deals with the Devil
Lil Spewer	384		Unlocked a new item.	Have Isaac die to his own explosion from Ipecac, Bob's Rotten Head, or a Horf! pill
Blanket	385		Unlocked a new item.	Sleep in 10 beds
Marbles	386		Unlocked a new item.	Use 5 Gulp! pills in one run (Placebo uses count)
Mystery Egg	387		Unlocked a new item.	Spawn three charmed enemies in the same room
Rotten Penny	388		Unlocked a new item.	Have 20 Blue Flies at the same time
Baby-Bender	389		Unlocked a new item.	Use I - The Magician or Telepathy For Dummies while already having homing tears
The Forgotten	390		Unlocked a new character.	It's complicated
Bone Heart	391		Unlocked a new item.	It's complicated
Marrow	392		Unlocked a new item.	Defeat Mom's Heart or It Lives! on Hard mode as The Forgotten
Slipped Rib	393		Unlocked a new item.	Defeat Isaac as The Forgotten
Pointy Rib	394		Unlocked a new item.	Defeat Satan as The Forgotten
Jaw Bone	395		Unlocked a new item.	Defeat ??? as The Forgotten
Brittle Bones	396		Unlocked a new item.	Defeat The Lamb as The Forgotten
Divorce Papers	397		Unlocked a new item.	Complete the Boss Rush as The Forgotten
Hallowed Ground	398		Unlocked a new item.	Defeat Hush as The Forgotten
Finger Bone	399		Unlocked a new item.	Defeat Ultra Greed as The Forgotten
Dad's Ring	400		Unlocked a new item.	Defeat Ultra Greedier as The Forgotten
Book of the Dead	401		Unlocked a new item.	Defeat Delirium as The Forgotten
Bone Baby	402		Unlocked a new co-player baby.	Earn all Hard mode Completion Marks as The Forgotten
Bound Baby	403		Unlocked a new co-player baby.	Defeat Mega Satan as The Forgotten
Bethany	404		Beat Hard mode as Lazarus without losing a life	Defeat Mom's Heart/ It Lives! on hard mode as Lazarus, without dying at all
Jacob and Esau	405		You are just like your father...	Defeat Mother
The Planetarium	406		Kids shouldn't believe in fortunes...	Collect any 3 items with the 'stars' item tag in a single run
A Secret Exit	407		Complete ??? 3 times.	Defeat Hush 3 times
Forgotten Lullaby	408		Get that song out of her head.	Blow up The Siren's skull after defeating her
Fruity Plum	409		Defeat Baby Plum 10 times.	Defeat Baby Plum 10 times
Plum Flute	410		Make a new friend!	Allow Baby Plum to escape instead of defeating her
Rotten Heart	411		Enter the Corpse...	Enter Corpse for the first time
Dross	412		Defeat all bosses in Downpour.	Defeat all bosses in Downpour
Ashpit	413		Defeat all bosses in the Mines.	Defeat all bosses in Mines
Gehenna	414		Defeat all bosses in the Mausoleum.	Defeat all bosses in Mausoleum
Red Key	415		The other side is calling...	Open Mom's Chest in Home
Wisp Baby	416		Beat the game in Hard mode with Bethany.	Defeat Mom's Heart or It Lives! on Hard mode as Bethany
Book of Virtues	417		Complete the Cathedral with Bethany.	Defeat Isaac as Bethany
Urn of Souls	418		Complete Sheol with Bethany.	Defeat Satan as Bethany
Blessed Penny	419		Complete the Chest with Bethany.	Defeat ??? as Bethany
Alabaster Box	420		Complete the Dark Room with Bethany.	Defeat The Lamb as Bethany
Beth's Faith	421		Complete Boss Rush with Bethany.	Complete the Boss Rush as Bethany
Soul Locket	422		Beat Greed mode with Bethany.	Defeat Ultra Greed as Bethany
Divine Intervention	423		Complete ??? with Bethany.	Defeat Hush as Bethany
Vade Retro	424		Beat Greedier mode with Bethany.	Defeat Ultra Greedier as Bethany
Star of Bethlehem	425		Beat the Void with Bethany.	Defeat Delirium as Bethany
Hope Baby	426		Beat everything in Hard mode with Bethany.	Earn all Hard mode Completion Marks as Bethany
Glowing Baby	427		Defeat Mega Satan with Bethany.	Defeat Mega Satan as Bethany
Double Baby	428		Beat the game in Hard mode with Jacob and Esau.	Defeat Mom's Heart or It Lives! on Hard mode as Jacob and Esau
The Stairway	429		Complete the Cathedral with Jacob and Esau.	Defeat Isaac as Jacob and Esau
Red Stew	430		Complete Sheol with Jacob and Esau.	Defeat Satan as Jacob and Esau
Birthright	431		Complete the Chest with Jacob and Esau.	Defeat ??? as Jacob and Esau
Damocles	432		Complete the Dark Room with Jacob and Esau.	Defeat The Lamb as Jacob and Esau
Rock Bottom	433		Complete Boss Rush with Jacob and Esau.	Complete Boss Rush as Jacob and Esau
Inner Child	434		Beat Greed mode with Jacob and Esau.	Defeat Ultra Greed as Jacob and Esau
Vanishing Twin	435		Complete ??? with Jacob and Esau.	Defeat Hush as Jacob and Esau
Genesis	436		Beat Greedier mode with Jacob and Esau.	Defeat Ultra Greedier as Jacob and Esau
Suplex!	437		Complete the Void with Jacob and Esau.	Defeat Delirium as Jacob and Esau
Solomon's Baby	438		Beat everything in Hard mode with Jacob and Esau.	Earn all Hard mode Completion Marks as Jacob and Esau
Illusion Baby	439		Defeat Mega Satan with Jacob and Esau.	Defeat Mega Satan as Jacob and Esau
Meat Cleaver	440		Complete the Corpse with Isaac.	Defeat Mother as Isaac
Options?	441		Complete the final chapter with Isaac.	Defeat The Beast as Isaac
Yuck Heart	442		Complete the Corpse with Magdalene.	Defeat Mother as Magdalene
Candy Heart	443		Complete the final chapter with Magdalene.	Defeat The Beast as Magdalene
Guppy's Eye	444		Complete the Corpse with Cain.	Defeat Mother as Cain
A Pound of Flesh	445		Complete the final chapter with Cain.	Defeat The Beast as Cain
Akeldama	446		Complete the Corpse with Judas.	Defeat Mother as Judas
Redemption	447		Complete the final chapter with Judas.	Defeat The Beast as Judas
Eternal D6	448		Complete the Corpse with ???.	Defeat Mother as ???
Montezuma's Revenge	449		Complete the final chapter with ???.	Defeat The Beast as ???
Bird Cage	450		Complete the Corpse with Eve.	Defeat Mother as Eve
Cracked Orb	451		Complete the final chapter with Eve.	Defeat The Beast as Eve
Bloody Gust	452		Complete the Corpse with Samson.	Defeat Mother as Samson
Empty Heart	453		Complete the final chapter with Samson.	Defeat The Beast as Samson
Devil's Crown	454		Complete the Corpse with Azazel.	Defeat Mother as Azazel
Lil Abaddon	455		Complete the final chapter with Azazel.	Defeat The Beast as Azazel
Tinytoma	456		Complete the Corpse with Lazarus.	Defeat Mother as Lazarus
Astral Projection	457		Complete the final chapter with Lazarus.	Defeat The Beast as Lazarus
'M	458		Complete the Corpse with Eden.	Defeat Mother as Eden
Everything Jar	459		Complete the final chapter with Eden.	Defeat The Beast as Eden
Lost Soul	460		Complete the Corpse with the Lost.	Defeat Mother as The Lost
Hungry Soul	461		Complete the final chapter with the Lost.	Defeat The Beast as The Lost
Blood Puppy	462		Complete the Corpse with Lilith.	Defeat Mother as Lilith
C Section	463		Complete the final chapter with Lilith.	Defeat The Beast as Lilith
Keeper's Sack	464		Complete the Corpse with Keeper.	Defeat Mother as Keeper
Keeper's Box	465		Complete the final chapter with Keeper.	Defeat The Beast as Keeper
Lil Portal	466		Complete the Corpse with Apollyon.	Defeat Mother as Apollyon
Worm Friend	467		Complete the final chapter with Apollyon.	Defeat The Beast as Apollyon
Bone Spurs	468		Complete the Corpse with the Forgotten.	Defeat Mother as The Forgotten
Spirit Shackles	469		Complete the final chapter with the Forgotten.	Defeat The Beast as The Forgotten
Revelation	470		Complete the Corpse with Bethany.	Defeat Mother as Bethany
Jar of Wisps	471		Complete the final chapter with Bethany.	Defeat The Beast as Bethany
Magic Skin	472		Complete the Corpse with Jacob and Esau.	Defeat Mother as Jacob and Esau
Friend Finder	473		Complete the final chapter with Jacob and Esau.	Defeat The Beast as Jacob and Esau
The Broken	474		???	Use Red Key (etc.) to open the hidden closet in Home as Isaac
The Dauntless	475		???	Use Red Key (etc.) to open the hidden closet in Home as Magdalene
The Hoarder	476		???	Use Red Key (etc.) to open the hidden closet in Home as Cain
The Deceiver	477		???	Use Red Key (etc.) to open the hidden closet in Home as Judas
The Soiled	478		???	Use Red Key (etc.) to open the hidden closet in Home as ???
The Curdled	479		???	Use Red Key (etc.) to open the hidden closet in Home as Eve
The Savage	480		???	Use Red Key (etc.) to open the hidden closet in Home as Samson
The Benighted	481		???	Use Red Key (etc.) to open the hidden closet in Home as Azazel
The Enigma	482		???	Use Red Key (etc.) to open the hidden closet in Home as Lazarus
The Capricious	483		???	Use Red Key (etc.) to open the hidden closet in Home as Eden
The Baleful	484		???	Use Red Key (etc.) to open the hidden closet in Home as The Lost
The Harlot	485		???	Use Red Key (etc.) to open the hidden closet in Home as Lilith
The Miser	486		???	Use Red Key (etc.) to open the hidden closet in Home as Keeper
The Empty	487		???	Use Red Key (etc.) to open the hidden closet in Home as Apollyon
The Fettered	488		???	Use Red Key (etc.) to open the hidden closet in Home as The Forgotten
The Zealot	489		???	Use Red Key (etc.) to open the hidden closet in Home as Bethany
The Deserter	490		???	Use Red Key (etc.) to open the hidden closet in Home as Jacob and Esau
Glitched Crown	491		???	Defeat The Beast as Tainted Isaac
Belly Jelly	492		???	Defeat The Beast as Tainted Magdalene
Blue Key	493		???	Defeat The Beast as Tainted Cain
Sanguine Bond	494		???	Defeat The Beast as Tainted Judas
The Swarm	495		???	Defeat The Beast as Tainted ???
Heartbreak	496		???	Defeat The Beast as Tainted Eve
Larynx	497		???	Defeat The Beast as Tainted Samson
Azazel's Rage	498		???	Defeat The Beast as Tainted Azazel
Salvation	499		???	Defeat The Beast as Tainted Lazarus
TMTRAINER	500		???	Defeat The Beast as Tainted Eden
Sacred Orb	501		???	Defeat The Beast as Tainted Lost
Twisted Pair	502		???	Defeat The Beast as Tainted Lilith
Strawman	503		???	Defeat The Beast as Tainted Keeper
Echo Chamber	504		???	Defeat The Beast as Tainted Apollyon
Isaac's Tomb	505		???	Defeat The Beast as Tainted Forgotten
Vengeful Spirit	506		???	Defeat The Beast as Tainted Bethany
Esau Jr.	507		???	Defeat The Beast as Tainted Jacob
Bloody Mary	508		Unlocked a new challenge.	Unlock Bethany, Blood Bag, and It Lives!
Baptism by Fire	509		Unlocked a new challenge.	Defeat Satan as Bethany, defeat Mom's Heart 11 times, and unlock Maggy's Faith
Isaac's Awakening	510		Unlocked a new challenge.	Defeat Mother
Seeing Double	511		Unlocked a new challenge.	Defeat Mother
Pica Run	512		Unlocked a new challenge.	Defeat Mom's Heart 11 times and unlock Marbles
Hot Potato	513		Unlocked a new challenge.	Unlock Tainted Forgotten
Cantripped!	514		Unlocked a new challenge.	Unlock Tainted Cain
Red Redemption	515		Unlocked a new challenge.	Unlock Tainted Jacob
DELETE THIS	516		TODO: remove this achievement	Unlock Tainted Eden
Dirty Mind	517		Complete Challenge 36.	Complete Scat Man (challenge #36)
Sigil of Baphomet	518		Complete Challenge 37.	Complete Bloody Mary (challenge #37)
Purgatory	519		Complete Challenge 38.	Complete Baptism by Fire (challenge #38)
Spirit Sword	520		Complete Challenge 39.	Complete Isaac's Awakening (challenge #39)
Broken Glasses	521		Complete Challenge 40.	Complete Seeing Double (challenge #40)
Ice Cube	522		Complete Challenge 41.	Complete Pica Run (challenge #41)
Charged Penny	523		They will charge you up... for a small fee.	Donate to Battery Bums until they pay out with an item 5 times
The Fool	524		???	Defeat Ultra Greedier as Tainted Lost
The Magician	525		???	Defeat Ultra Greedier as Tainted Judas
The High Priestess	526		???	Defeat Ultra Greedier as Tainted Lilith
The Empress	527		???	Defeat Ultra Greedier as Tainted Eve
The Emperor	528		???	Defeat Ultra Greedier as Tainted ???
The Hierophant	529		???	Defeat Ultra Greedier as Tainted Bethany
The Lovers	530		???	Defeat Ultra Greedier as Tainted Magdalene
The Chariot	531		Complete Challenge 42.	Complete Hot Potato (challenge #42)
Justice	532		Complete Challenge 43.	Complete Cantripped (challenge #43)
The Hermit	533		Complete Challenge 44.	Complete Red Redemption (challenge #44)
Wheel of Fortune	534		???	Defeat Ultra Greedier as Tainted Cain
Strength	535		???	Defeat Ultra Greedier as Tainted Samson
The Hanged Man	536		???	Defeat Ultra Greedier as Tainted Keeper
Death	537		???	Defeat Ultra Greedier as Tainted Forgotten
Temperance	538		INVALID_DESCRIPTION	Complete DELETE THIS (challenge #45)
The Devil	539		???	Defeat Ultra Greedier as Tainted Azazel
The Tower	540		???	Defeat Ultra Greedier as Tainted Apollyon
The Stars	541		???	Defeat Ultra Greedier as Tainted Isaac
The Sun and the Moon	542		???	Defeat Ultra Greedier as Tainted Jacob
Judgement	543		???	Defeat Ultra Greedier as Tainted Lazarus
The World	544		???	Defeat Ultra Greedier as Tainted Eden
Old Capacitor	545		Kill 10 Battery Bums.	Kill 10 Battery Bums
Brimstone Bombs	546		Kill Hornfel before he escapes!	After breaking Hornfel's minecart, kill him before he can escape
Mega Mush	547		Beat everything in Hard Mode as every character.	Earn all Hard mode Completion Marks for all non-Tainted characters
Mom's Lock	548		???	Defeat Isaac, ???, Satan, and The Lamb as Tainted Isaac
Dice Bag	549		???	Defeat Mother as Tainted Isaac
Holy Crown	550		???	Defeat Isaac, ???, Satan, and The Lamb as Tainted Magdalene
Mother's Kiss	551		???	Defeat Mother as Tainted Magdalene
Gilded Key	552		???	Defeat Isaac, ???, Satan, and The Lamb as Tainted Cain
Lucky Sack	553		???	Defeat Mother as Tainted Cain
Your Soul	554		???	Defeat Isaac, ???, Satan, and The Lamb as Tainted Judas
Number Magnet	555		???	Defeat Mother as Tainted Judas
Dingle Berry	556		???	Defeat Isaac, ???, Satan, and The Lamb as Tainted ???
Ring Cap	557		???	Defeat Mother as Tainted ???
Strange Key	558		???	Defeat Isaac, ???, Satan, and The Lamb as Tainted Eve
Lil Clot	559		???	Defeat Mother as Tainted Eve
Temporary Tattoo	560		???	Defeat Isaac, ???, Satan, and The Lamb as Tainted Samson
Swallowed M80	561		???	Defeat Mother as Tainted Samson
Wicked Crown	562		???	Defeat Isaac, ???, Satan, and The Lamb as Tainted Azazel
Azazel's Stump	563		???	Defeat Mother as Tainted Azazel
Torn Pocket	564		???	Defeat Isaac, ???, Satan, and The Lamb as Tainted Lazarus
Torn Card	565		???	Defeat Mother as Tainted Lazarus
Nuh Uh!	566		???	Defeat Isaac, ???, Satan, and The Lamb as Tainted Eden
Modeling Clay	567		???	Defeat Mother as Tainted Eden
Kid's Drawing	568		???	Defeat Isaac, ???, Satan, and The Lamb as Tainted Lost
Crystal Key	569		???	Defeat Mother as Tainted Lost
The Twins	570		???	Defeat Isaac, ???, Satan, and The Lamb as Tainted Lilith
Adoption Papers	571		???	Defeat Mother as Tainted Lilith
Keeper's Bargain	572		???	Defeat Isaac, ???, Satan, and The Lamb as Tainted Keeper
Cursed Penny	573		???	Defeat Mother as Tainted Keeper
Cricket Leg	574		???	Defeat Isaac, ???, Satan, and The Lamb as Tainted Apollyon
Apollyon's Best Friend	575		???	Defeat Mother as Tainted Apollyon
Polished Bone	576		???	Defeat Isaac, ???, Satan, and The Lamb as Tainted Forgotten
Hollow Heart	577		???	Defeat Mother as Tainted Forgotten
Expansion Pack	578		???	Defeat Isaac, ???, Satan, and The Lamb as Tainted Bethany
Beth's Essence	579		???	Defeat Mother as Tainted Bethany
RC Remote	580		???	Defeat Isaac, ???, Satan, and The Lamb as Tainted Jacob
Found Soul	581		???	Defeat Mother as Tainted Jacob
Member Card	582		Spend 40+ pennies in a single shop.	Spend 40+ coins in a single Shop
Golden Razor	583		Obtain 99 pennies. Then spend every single one of them.	In a single run, obtain 99 Coins, then spend all of them
Spindown Dice	584		???	Defeat Delirium as Tainted Isaac
Hypercoagulation	585		???	Defeat Delirium as Tainted Magdalene
Bag of Crafting	586		???	Defeat Delirium as Tainted Cain
Dark Arts	587		???	Defeat Delirium as Tainted Judas
IBS	588		???	Defeat Delirium as Tainted ???
Sumptorium	589		???	Defeat Delirium as Tainted Eve
Berserk!	590		???	Defeat Delirium as Tainted Samson
Hemoptysis	591		???	Defeat Delirium as Tainted Azazel
Flip	592		???	Defeat Delirium as Tainted Lazarus
Corrupted Data	593		???	Defeat Delirium as Tainted Eden
Ghost Bombs	594		???	Defeat Delirium as Tainted Lost
Gello	595		???	Defeat Delirium as Tainted Lilith
Keeper's Kin	596		???	Defeat Delirium as Tainted Keeper
Abyss	597		???	Defeat Delirium as Tainted Apollyon
Decap Attack	598		???	Defeat Delirium as Tainted Forgotten
Lemegeton	599		???	Defeat Delirium as Tainted Bethany
Anima Sola	600		???	Defeat Delirium as Tainted Jacob
Mega Chest	601		???	Defeat Mega Satan as Tainted Isaac
Queen of Hearts	602		???	Defeat Mega Satan as Tainted Magdalene
Gold Pill	603		???	Defeat Mega Satan as Tainted Cain
Black Sack	604		???	Defeat Mega Satan as Tainted Judas
Charming Poop	605		???	Defeat Mega Satan as Tainted ???
Horse Pill	606		???	Defeat Mega Satan as Tainted Eve
Crane Game	607		???	Defeat Mega Satan as Tainted Samson
Hell Game	608		???	Defeat Mega Satan as Tainted Azazel
Wooden Chest	609		???	Defeat Mega Satan as Tainted Lazarus
Wild Card	610		???	Defeat Mega Satan as Tainted Eden
Haunted Chest	611		???	Defeat Mega Satan as Tainted Lost
Fool's Gold	612		???	Defeat Mega Satan as Tainted Lilith
Golden Penny	613		???	Defeat Mega Satan as Tainted Keeper
Rotten Beggar	614		???	Defeat Mega Satan as Tainted Apollyon
Golden Battery	615		???	Defeat Mega Satan as Tainted Forgotten
Confessional	616		???	Defeat Mega Satan as Tainted Bethany
Golden Trinket	617		???	Defeat Mega Satan as Tainted Jacob
Soul of Isaac	618		???	Defeat Hush and Boss Rush as Tainted Isaac
Soul of Magdalene	619		???	Defeat Hush and Boss Rush as Tainted Magdalene
Soul of Cain	620		???	Defeat Hush and Boss Rush as Tainted Cain
Soul of Judas	621		???	Defeat Hush and Boss Rush as Tainted Judas
Soul of ???	622		???	Defeat Hush and Boss Rush as Tainted ???
Soul of Eve	623		???	Defeat Hush and Boss Rush as Tainted Eve
Soul of Samson	624		???	Defeat Hush and Boss Rush as Tainted Samson
Soul of Azazel	625		???	Defeat Hush and Boss Rush as Tainted Azazel
Soul of Lazarus	626		???	Defeat Hush and Boss Rush as Tainted Lazarus
Soul of Eden	627		???	Defeat Hush and Boss Rush as Tainted Eden
Soul of the Lost	628		???	Defeat Hush and Boss Rush as Tainted Lost
Soul of Lilith	629		???	Defeat Hush and Boss Rush as Tainted Lilith
Soul of the Keeper	630		???	Defeat Hush and Boss Rush as Tainted Keeper
Soul of Apollyon	631		???	Defeat Hush and Boss Rush as Tainted Apollyon
Soul of the Forgotten	632		???	Defeat Hush and Boss Rush as Tainted Forgotten
Soul of Bethany	633		???	Defeat Hush and Boss Rush as Tainted Bethany
Soul of Jacob and Esau	634		???	Defeat Hush and Boss Rush as Tainted Jacob
A Strange Door	635		Where could it lead to?	Defeat Mother
Death Certificate	636		...	Earn all Hard mode Completion Marks for all characters, including tainted ones
Dead God	637		{{{description}}}	Unlock all the other achievements ( including the 3 Repentance+ achievements) and collect every item in the game
Play Online	638		Played Online	Play an Online game
Win Online	639		Won Online	Win an Online run
Win Online Daily	640		Won Online Daily	Win an Online Daily run

PlayStation Trophies

Name	Image	Unlock
Platinum		Obtain all trophies
Isaac's Tears		Kill Isaac with Isaac
Mom's Knife		Kill Satan with Isaac
Isaac's Heart		Kill Isaac with The Lost
The Mind		Kill Satan with The Lost
Magdalene		Have 7 or more heart containers at one time
The Relic		Kill Isaac with Maggy
Guardian Angel		Kill Satan with Maggy
Cain		Hold 55 coins at one time
The Coin Bag		Kill Isaac with Cain
The Bomb Bag		Kill Satan with Cain
Judas		Kill Satan for the 1st time
The Guillotine		Kill Isaac with Judas
Judas' Tongue		Kill Satan with Judas
Eve		Don't pick up any hearts for 2 floors in a row
Eve's Bird Foot		Kill Isaac with Eve
The Razor		Kill Satan with Eve
Samson		Beat 2 floors in a row without taking damage
Bloody Lust		Kill Isaac with Samson
Blood Rights		Kill Satan with Samson
Azazel		Make 3 deals with the devil in one run
Satanic Bible		Kill Isaac with Azazel
Daemon's Tail		Kill Satan with Azazel
Lazarus		Have 4 or more soul hearts at one time
Lazarus' Rags		Kill Isaac with Lazarus
Broken Ankh		Kill Satan with Lazarus
Eden		Beat Chapter 4 for the 1st time
Blank Card		Kill Isaac with Eden
The Book of Secrets		Kill Satan with Eden
Something From The Future		Beat The Basement 40 times.
Something Cute		Beat Chapter 2 30 times
Something Sticky		Beat Chapter 3 20 times
Basement Boy		Beat Chapter 1 without taking damage
Spelunker Boy		Beat Chapter 2 without taking damage
Dark Boy		Beat Chapter 3 without taking damage
Mama's Boy		Beat Chapter 4 without taking damage
Dead Boy		Beat The Chest or Dark Room without taking damage
Challenges		Beat all 20 Challenges
Boss Rush		Beat the Boss Rush
Dark Room		Beat the Dark Room
The Chest		Beat The Chest
Lost Poster		Beat Dark Room with Isaac
Little Baggy		Collect 2 of either roid rage, the virus, growth hormones, experimental treatment or speed ball
The Womb		Kill Mom for the 1st time
The Halo		Kill Mom using The Bible
Transcendence		Kill Mom's Heart 3 times
Everything is Terrible		Kill Mom's Heart 5 times
A Quarter		Kill Mom's Heart 8 times
A Fetus in a Jar		Kill Mom's Heart 9 times
Blue Baby		Kill Mom's Heart 10 times
It Lives!		Kill Mom's Heart 11 times
Forget Me Now		Kill Satan with ???
The Book of Sin		Kill all 7 Sins
The Polaroid		Kill Isaac 5 times
The Negative		Kill Satan 5 times
Golden God		Kill ??? and The Lamb
Platinum God		Collect all items in the game, unlock all of the secrets and Endings minus The Lost and his 7 unlockable items
The Lost		Unlock The Lost
Real Platinum God		Collect every Item and unlock every ending.

Notes

• The 5 Nights at Mom's achievement is bugged in various ways:
  • Because the game uses 32-bit architecture and has 41 characters, the game counts wins twice for the first 9 characters. That means if in your streak you play once with a character from Isaac to Lazarus, you will get the achievement with 4 wins. If you play with two characters from Isaac to Lazarus, you will get the achievement with 3 wins. Since the game uses 64-bit architecture on consoles, this bug is PC-only.
  • Using normal Characters to get a win and then using its tainted counterpart won't work, only one of them will work for obtaining the achievement.
    • Additionally, due to integer overflow, some tainted characters share the same bitmask with some normal characters. The game resets the achievement streak counter if two runs are done with characters with the same bitmask. Tainted Lilith has the same bitmask as Isaac. Here are the pairs of characters that have the same bitmask : Tainted Keeper and Magdalene, Tainted Apollyon and Cain, Tainted Forgotten and Lazarus, Tainted Bethany and ???, Tainted Jacob and Eve, Tainted Dead Lazarus and Samson, Tainted Jacob in Lost form and Azazel. If you did a run with Isaac or Lilith, do not finish a run with Tainted Lilith or the counter will reset. Not confirmed yet but by the same logic as the bug above, this one is likely PC-only too.
  • The achievement does not unlock in Co-op Repentance, even if the five wins were done with different characters for each player.
  • Modded characters do not interfere with the streaks, and do not reset nor increment the counter.

Trivia

• Each achievement is color-coded based on the requirements for unlocking their respective secrets:
  • Tan: Miscellaneous unlocks
  • Tan with blood stain: Mom's Heart / It Lives! Hard Mode unlocks
  • Olive-Green: Character unlocks
  • Dark Red: Mom's Heart / Womb ending unlocks
  • Grey: Isaac unlocks
  • Black: Satan unlocks
  • Dark Blue: ??? unlocks
  • Purple: The Lamb unlocks
  • Pale Green: Boss Rush unlocks
  • Pale Blue: Hush unlocks
  • Orange Yellow: Greed Mode unlocks
  • Orange Yellow with blood stain: Greedier mode unlocks
  • White: Delirium unlocks
  • Red: Mega Satan unlocks
  • Bright Yellow: All Hard Mode marks (most are tan)/Damageless floor/100% unlocks
  • Brighter Yellow: Greed Donation Machine unlocks
  • Bluish Purple: Challenge unlocks
  • Dark Green with bloodstain: Mother unlocks
  • Orange: The Beast unlocks
  • Bright Purple: Tainted Character unlocks
• Despite being a Boss Rush unlock for Lazarus, Missing No.'s achievement color is bluish purple, a color normally used for challenge-related unlocks.
• Achievements 37-41 and 83 have a typo on their pop-ups, and read "achieveved".
• Despite unlocking Locust of War, achievement 310 is named "Locust of Wrath".
• Although not technically an achievement, getting 1000000% on all 3 save files will result in a special 3,000,000%!!! graphic on the save file selection screen.
  • In Repentance, something similar happens when achieving Dead God on all 3 save files.
• The 5 Nights at Mom's achievement is a reference to Five Nights at Freddy's.
• The Mr. Resetter achievement may be a reference to Mr. Resetti from the Animal Crossing series.
• The Something Wicked This Way Comes quote is most likely a reference to the same quote from one of the witches from Shakespeare's play "Macbeth." It may also be a reference to the Ray Bradbury novel of the same name, which in turn, is also a reference to Macbeth.
• Booster Pack #5 added 64 secrets. Interestingly, this is a single secret more than Afterbirth+'s original count of 63 secrets. Thus, this update more than doubled the amount of secrets added to the game.

PS4 Achievements 340-348 don't exist in the PS4 version, resulting in the content already being "unlocked" even on new save files.

• Achievements 638 to 640 are currently part of the Online Co-op beta and are not available in the base game and are not yet added to Steam. Achievement 640 is not even implemented and not obtainable in the beta.

• Despite having no achievement description normally, if the player attempts to showcase the Dead God achievement on their Steam Profile using the Achievement Showcase element, a small description will pop up that reads "NEW_ACHIEVEMENT_22_16_DESC".
• Like Monster Manual, the achievement Dead God is a reference to the Dead Gods adventure module for the second edition of wikipedia:Advanced Dungeons & Dragons.

Bugs

Bug!	Clear Rune must be unlocked and collected to attain !Platinum God! and The Real Platinum God despite being a Repentance item. This is due to its ID being unused in Rebirth, thus being in the ID range of Rebirth items.

Bug!	PS4 If installed, before unlocking it, the 'Challenges' trophy will require completing all the challenges available on the current DLC played instead of the original 20 Challenges.

Bug!	Buddy in a Box also counts collectible effects towards its progress. Getting hit 5 times in a room with one Best Bud or getting Paschal Candle to level 4 count as having 5 familiars.

References

The Binding of Isaac: Rebirth
Achievements Challenges Completion Marks Items Trinkets Characters Chapters Rooms Transformations Attributes Bosses Monsters Pickups Modes Curses Objects Seeds Effects Endings
Collection Item Pools Version History Modding Music