Status Effects

This article is about effects which can be inflicted on monsters. For the different kinds of effects which Isaac's primary weapon can have, see Tear Effects.

Status effects are special effects that can be inflicted on an enemy from a variety of sources, such as tears, bombs, and items. Each status effect has a color and/or symbol/effect associated with them for easy identification. These colorations are not to be confused with champions.

Effects

Effect	Appearance	Description
Burn		Afflicted enemies take 4 to 6 fire damage over time. Afflicted enemies will be tinted orange for the duration and have a fire symbol above them. Afflicted enemies will sustain double Isaac's tear damage over time. Afflicted enemies will be tinted orange for the duration and have a fire symbol above them.
Charm		Afflicted enemies will temporarily fight on Isaac's side, running toward and/or shooting at other enemies and damaging them for 25% of their maximum HP per touch, 5 damage with half-heart-dealing projectiles, and 10 with full-heart-dealing projectiles. If no other enemies are in the room, a charmed enemy will instead run towards Isaac. (Charmed enemies can still hurt Isaac.) Afflicted enemies will be tinted pink for the duration and have a heart symbol above them. Most enemies with ranged attacks will not fire them (but can damage other enemies with them if they do — see the above "monster infighting" damage description). Charmed enemies will prioritize non-charmed enemies and won't target invincible enemies. Charmed Portals will also spawn friendly enemies.
Confusion/Concussion		Afflicted enemies are slowed and walk around randomly. While confused, most non-boss enemies will be unable to attack. Bosses will have randomized movement, but will still be able to fire projectiles at Isaac. Afflicted enemies will be tinted pale gray and have stars above them.
Fear		Afflicted enemies are scared of Isaac and will run away from him. While scared, most non-boss enemies will be unable to attack or charge towards Isaac. Bosses will run away from Isaac, but will still be able to shoot projectiles at him. Afflicted enemies will be tinted purple and have a skull symbol above them.
Petrified		Afflicted enemies are stopped in place. They cannot move or attack. Afflicted enemies will be shaded brown-gray as if turned to stone (unless petrified by Midas' Touch, in which case they will be shaded gold).
Poison		Afflicted enemies sustain 4 to 6 damage over time. Afflicted enemies will be tinted green and have a bubbly effect surrounding them. Afflicted enemies will sustain double Isaac's tear damage over time. Afflicted enemies will be tinted green and have a bubbly effect surrounding them.
Slow		Afflicted enemies are slowed down to approximately 51.3% of their original speed. Any projectiles they shoot will also be slowed down to the same amount. Attacks that end when the enemy runs out of momentum, such as the charging attacks of Gurdy Jr. and Dingle, will be vastly shortened in duration. Depending on the item that triggers the slow effect, afflicted enemies will be tinted black or white with a snail icon above them. Slowed projectiles will lose momentum much more quickly, greatly reducing their total range.
Friendly		Afflicted enemies are permanently charmed and will fight on Isaac's side until they die. Most enemies under this effect will follow Isaac across rooms, like a familiar. Friendly enemies cannot hurt Isaac, but many of them will still chase and "attack" Isaac in a room with no enemies. Friendly enemies are not tinted, but have heart symbols above their head.
Shrink		Afflicted enemies are shrunken and will run away from Isaac. Isaac can walk over shrunken enemies to kill them.
Bleed		Afflicted enemies take damage equal to 10% of their maximum health every 5 seconds. Afflicted enemies take damage based on how quickly they move; the faster the enemy, the more damage they take. While moving, a bleeding enemy leaves behind red creep that can damage other enemies.
Bait		Afflicted enemies will be attacked by other enemies, functioning like a reverse charm effect. Afflicted enemies are tinted red.
Chained		Afflicted enemies are chained in place, preventing them from taking any action.
Frozen		Enemies that are killed by items that can inflict Frozen become ice statues on death that block both Isaac's tears and enemy shots. Ice statues can also be pushed by Isaac, causing them to slide, leaving damaging blue creep (which deals 22 damage per second), until they hit an obstacle or enemy, dealing 35 damage to enemies they collide with. After an ice statue blocks 10 shots or collides with something while sliding, it shatters into a ring of 10 icicles which slow and deal 8 + (floor − 1) damage to enemies they hit. Enemies that are killed by these icicles also become ice statues. Frozen enemies will not trigger any of their on-death effects, such as exploding or splitting, making this effect useful for enemies with multiple forms.

Notes

• Host-type enemies will take burn and poison damage even if their skull is down, and all status effects can be applied by tears even if their skulls are down.
  • If a Host-type enemy is petrified, they will take damage regardless of if they are vulnerable or not.
• After a boss or mini-boss has had a status effect applied on them, they will receive immunity against all status effects for 8 seconds. This means that no other status effect can be applied to that enemy during this period.
  • The slow effect is an exception to this rule.

Burn

Passive items that cause burning

Name	ID	Icon	Quote	Description	Quality
Fire Mind	5.100.257		Flaming tears	Grants flaming tears that deal burning damage over time. Tears have a chance to explode on impact with an enemy, which creates a fire at the location of the explosion.	2

Trinkets that cause burning

Name	ID	Icon	Quote	Description
A Lighter	5.350.135		Watch the world burn	Adds a chance for enemies to burn upon entering a room.

Other sources that burn enemies

• Judas' Birthright effect will inflict Burn on nearby enemies when using an active item.
• When playing as Tainted Jacob, Dark Esau inflicts Burn on enemies he passes through whilst dashing.

Charm

Activated items that cause charming

Name	ID	Icon	Quote	Description	Quality
Kidney Bean	5.100.421		Love toots!	Isaac farts, charming all nearby enemies.	1

Passive items that cause charming

Name	ID	Icon	Quote	Description	Quality
Ball of Bandages	5.100.207		Gotta lick 'em all!	Creates an orbital familiar. Collecting additional copies gives it the ability to shoot Charm tears, then chase enemies to deal contact damage, then deal even more contact damage.	2
Mom's Eyeshadow	5.100.200		Charm tears	Tears have a chance to charm enemies.	1
Farting Baby	5.100.404		He farts!	Spawns a familiar that follows Isaac and blocks enemy shots. If a shot hits Farting Baby, it has a chance to fart, which charms, poisons, or knocks back nearby enemies.	1
Glitter Bombs	5.100.432		Prize bombs!	+5 Bombs. Bombs have a chance to drop random pickups or charm enemies when they explode.	2
Bozo	5.100.513		Party time!	+0.1 flat damage, grants a Soul Heart. Enemies can randomly become briefly charmed or feared. Taking damage has a chance to spawn a Rainbow Poop.	2
Venus	5.100.591		HP up + you feel pretty	Adds one red Heart container. Heals 1 additional Red Heart. Enemies near Isaac become charmed.	2
Sissy Longlegs	5.100.280		She loves you	Spawns a familiar that wanders randomly, occasionally spawning Blue Spiders. Briefly charms enemies on contact.	1
Betrayal	5.100.391		Turn your enemy	Charms all enemies in the room when Isaac takes damage. Enemies are able to damage each other. If an enemy is damaged by another enemy, they will attack that enemy instead of Isaac.	1

Pills that cause charming

Pill	Effect
Pheromones	Charms all enemies in the room for a short period of time.

Notes

• First stage of Ball of Bandages cannot charm enemies. See Ball of Bandages for details.
• Charmed enemies will still target Isaac if they are the only enemy in the room.

Confusion

Passive items that cause confusion

Name	ID	Icon	Quote	Description	Quality
Butt Bombs	5.100.209		Toxic blast +5 bombs	+5 Bombs. Bombs now cloud up the screen, briefly damaging and confusing all enemies.	2
Iron Bar	5.100.201		DMG up + concussive tears	+0.3 damage. Adds a chance to shoot concussive tears, causing enemies to walk around randomly.	2
Camo Undies	5.100.497		Camo kid	Isaac becomes camouflaged at the beginning of each room. Until he shoots, all non-boss enemies will be confused. Isaac gains +0.5 Speed while camouflaged, and gains Tears and Damage upon breaking it.	3
Glaucoma	5.100.460		Blind tears!	Adds a chance to shoot tears that confuse enemies for an extremely long time.	1
Metal Plate	5.100.449		It itches...	Grants one Soul Heart. Enemy shots have a chance to be reflected at the shooter as confusing tears.	1
Knockout Drops	5.100.637		They pack a punch!	Adds a chance to shoot a fist tear that has extremely high knockback and confuses enemies.	3

Trinkets that cause confusion

Name	ID	Icon	Quote	Description
Faded Polaroid	5.350.69		You feel faded	Occasionally causes Isaac to blend into the ground, which briefly confuses all enemies in the room. Can be used to open the Strange Door in The Depths.

Fear

Activated items that cause fear

Name	ID	Icon	Quote	Description	Quality
Mom's Pad	5.100.41		Mass fear	Inflicts fear to all enemies in the room for 4 seconds. Spawns a blue fly.	0
The Gamekid	5.100.93		Temporary Man-Pac	Turns Isaac into a Pac-Man-like creature for 6.5 seconds, granting invulnerability, inflicting fear on all enemies, and has a chance of replenishing a Half Red Heart every time an enemy is killed.	1

Passive Items that cause fear

Name	ID	Icon	Quote	Description	Quality
Abaddon	5.100.230		Evil + DMG up + fear shot	+1.5 damage, +0.2 speed. Removes all Red Heart containers, grants six Black Hearts, and adds a chance to shoot fear tears. +1.5 damage, +0.2 speed. Grants two Black Hearts, converts all Red Heart Containers into Black Hearts, and adds a chance to shoot fear tears.	3
Dark Matter	5.100.259		DMG up + fear shot	+1 damage, adds a chance to shoot fear tears.	3
Mom's Perfume	5.100.228		Fear shot + tears up	Adds a chance to shoot fear tears. Decreases tear delay by 1. +0.5 fire rate.	2
Spear Of Destiny	5.100.400		Your destiny	In addition to tears, Isaac holds a spear in front of him which deals contact damage equal to 2× his tear damage, and occasionally inflicts fear.	2
Bozo	5.100.513		Party time!	+0.1 flat damage, grants a Soul Heart. Enemies can randomly become briefly charmed or feared. Taking damage has a chance to spawn a Rainbow Poop.	2
2Spooky	5.100.554		4me	Enemies near Isaac are afflicted with fear.	1
My Shadow	5.100.433		Me! And my shaaaadow!	Inflicts fear on all enemies in the room upon taking damage and spawns black friendly Chargers that attack enemies. Spawns a shadow familiar that closely follows behind Isaac. It spawns a black friendly Charger whenever an enemy touches it.	2

Pills that cause fear

Pill	Effect
Power Pill!	Temporarily grants invulnerability, inflicts fear on enemies in the room, and lets Isaac deal contact damage, similar to The Gamekid.

Petrification

Activated items that petrify enemies

Name	ID	Icon	Quote	Description	Quality
Mom's Bra	5.100.39		Mass paralysis	Petrifies all enemies in the current room for 4 seconds.	1
The Boomerang	5.100.338		It will never leave you	Throws a boomerang which retrieves pickups, as well as damages and petrifies enemies hit for 2 seconds.	1
Mega Bean	5.100.351		Giga fart!	Petrifies all enemies in the current room for about 1.5 seconds, poisons any enemies near Isaac, and sends a rock wave across the room in the direction Isaac is facing.	1

Passive items that petrify enemies

Name	ID	Icon	Quote	Description	Quality
Midas' Touch	5.100.202		Golden touch	Enemies that touch Isaac are temporarily petrified and turn to gold. Any enemy killed while in this state will drop Pennies.	2
Mom's Contacts	5.100.110		Freeze effect	Adds a chance to shoot petrifying tears, which stop enemies in place and prevent them from moving or attacking. +0.25 range. +1.5 range.	3
Charged Baby	5.100.372		Bbbzzzzzt!	Spawns a familiar that occasionally drops a Lil' Battery, gives an active item charge, or petrifies all enemies in the room.	3
Dad's Ring	5.100.546		Father's blessing	Creates a ring of light around Isaac that petrifies enemies in contact.	3
Eye of Greed	5.100.450		Gold tears!	Every 20 tears, Isaac loses 1 Penny and shoots an additional gold tear that petrifies enemies and turns them into gold. Any enemy killed while in this state will drop coins.	2
Freezer Baby	5.100.608		Iced iced baby	Spawns a shooting familiar that has a chance to petrify enemies, and freezes monsters upon killing them.	2
Holy Water	5.100.178		Splash!	Spawns a bottle familiar that breaks when Isaac takes damage, leaving a puddle of blue creep. A bottle familiar that flies forward when Isaac shoots. It breaks upon hitting an enemy, leaving a puddle of blue creep that petrifies enemies.	3

Trinkets that petrify enemies

Name	ID	Icon	Quote	Description
Ice Cube	5.350.188		Stay frosty	Adds a chance to petrify enemies when entering the room. Killing the petrified enemy freezes it.

Other sources that petrify enemies

• Losing a Gold Heart briefly turns all nearby enemies into gold.

Poison

Activated items that poison enemies

Name	ID	Icon	Quote	Description	Quality
Bob's Rotten Head	5.100.42		Reusable ranged bomb	Isaac holds a poison Bomb which can be thrown in the cardinal directions and explodes on impact.	1
The Bean	5.100.111		Toot on command	Isaac farts, poisoning any enemy in close range.	0
Mega Bean	5.100.351		Giga fart!	Petrifies all enemies in the current room for about 1.5 seconds, poisons any enemies near Isaac, and sends a rock wave across the room in the direction Isaac is facing.	1

Passive items that poison enemies

Name	ID	Icon	Quote	Description	Quality
Bob's Brain	5.100.273		Explosive thoughts	Spawns a familiar that charges forward when shooting tears and explodes upon contact with an enemy, damaging and poisoning them. The familiar respawns after a few seconds.	1
Bob's Curse	5.100.140		+5 poison bombs	+5 Bombs. Grants Isaac's bombs a poison effect. They also leave a lingering poison cloud, and Isaac becomes immune to poison.	1
Ipecac	5.100.149		Explosive shots	Replaces tears with explosive and poisoning projectiles fired in an arc from the mouth.	4
Scorpio	5.100.305		Poison tears	Grants poison tears, which deal damage over time when inflicted.	3
The Black Bean	5.100.180		Toot on touch	When taking damage, Isaac farts, poisoning enemies in range. When taking damage, Isaac farts five times, poisoning and knocking back nearby enemies and leaving lingering poison clouds.	0
The Common Cold	5.100.103		Poison damage	Adds a chance to shoot poison tears, dealing damage over time when inflicted.	1
The Virus	5.100.13		Poison touch + speed up	Isaac poisons enemies on contact. -0.1 speed. +0.2 speed. Poisoned enemies have a chance to drop a black heart when killed.	2
Farting Baby	5.100.404		He farts!	Spawns a familiar that follows Isaac and blocks enemy shots. If a shot hits Farting Baby, it has a chance to fart, which charms, poisons, or knocks back nearby enemies.	1
Serpent's Kiss	5.100.393		The kiss of death	Tears have a chance to apply a poison effect to enemies. Isaac poisons enemies on contact. Poisoned enemies have a chance to drop a Black Heart when killed.	2
Toxic Shock	5.100.350		Mass poison	Upon entering a room, poisons all enemies, dealing double Isaac's tear damage. Killing enemies leaves a small, short-lasting pool of green creep on the ground.	3
Acid Baby	5.100.491		Pills pills pills!	Spawns a familiar that drops a random pill every 3 rooms. Upon using a pill, all enemies in the room are poisoned.	2
Contagion	5.100.466		Outbreak!	The first enemy killed in a room releases a gas cloud that poisons nearby enemies. Affected enemies will also release gas upon death, spreading the effect.	2
Dead Tooth	5.100.446		Toxic breath	While firing, Isaac gains a green aura that poisons nearby enemies.	1
Jupiter	5.100.594		You're a gas giant!	+2 red Heart containers, -0.3 speed. Isaac builds speed while standing still, and releases poison gas clouds when he moves afterwards.	2
Mucormycosis	5.100.553		Spore shot	Gives Isaac the chance to fire spore tears that stick to enemies and blow up after a few seconds, dealing damage and poisoning nearby enemies and releasing more spores.	3

Trinkets that poison enemies

Name	ID	Icon	Quote	Description
Pinky Eye	5.350.30		Poison shots	Adds a 10% chance to shoot a poison tear, dealing damage over time when inflicted.
Black Tooth	5.350.95		It looks dead	Adds a chance to fire a black tooth that deals double damage and poisons enemies.
Locust of Pestilence	5.350.114		I bring Pestilence	Upon entering a room with enemies, spawns a Green Locust which damages and poisons enemies.
Torn Card	5.350.157		Death awaits	Every 15 shots, Isaac shoots an Ipecac + My Reflection tear.

Pills that poison enemies

Pill	Effect
Bad Gas	Isaac farts, poisoning enemies around him.

Slow

Activated items that slow enemies

Name	ID	Icon	Quote	Description	Quality
Spider Butt	5.100.171		Mass enemy slowdown + damage	Deals 10 damage to all enemies in the room and slows them for 4 seconds. Enemies killed by Spider Butt spawn Blue Spiders.	1
The Hourglass	5.100.66		Temporary enemy slowdown	All enemies in the room are slowed for 8 seconds.	1

Passive items that slow enemies

Name	ID	Icon	Quote	Description	Quality
Ball of Tar	5.100.231		Sticky feet...	Adds a chance to shoot slowing tears. Isaac leaves a trail of slowing creep behind as he moves, impeding enemies' speed.	2
Broken Watch	5.100.337		I think it's broken	Slows all enemies in every fourth newly-discovered room, with a small chance to speed them up instead.	1
Juicy Sack	5.100.266		Sticky babies	Spawns a familiar that follows Isaac and drips a trail of slow creep, spawning 1-2 Blue Spiders after each room.	2
Little Gish	5.100.99		Sticky friend	Spawns a familiar that follows Isaac around and fires slowing tears, impeding enemies' speed.	2
Spider Bite	5.100.89		Slow effect	Adds a chance to shoot slowing tears, reducing speed of enemy movement and any projectile fired by them.	2
Censer	5.100.387		Peace be with you	Spawns a familiar which creates a circular aura that slows down enemies and enemy shots inside.	3
Night Light	5.100.425		Scared of the dark?	A cone of light shines in the direction Isaac is moving that slows enemies and enemy shots.	1
Large Zit	5.100.502		Creep shots	Adds a chance to fire a creep shot that deals double damage and leaves a trail of slowing white creep.	1
Parasitoid	5.100.461		Egg tears!	Adds a chance to fire an egg sack which creates slowing creep and spawns a Blue Fly or Blue Spider upon hitting an enemy.	3
Cube Baby	5.100.652		Kick it!	Spawns an ice cube familiar that slides around when walked into. It slows and deals contact damage, freezing monsters it kills.	1
The Intruder	5.100.575		Invasive friend	A familiar burrows in Isaac's head, firing 4 slowing tears. Upon taking damage, there's a chance it will burst out of Isaac's head, spawning blue spiders and chasing enemies for the current room.	3
Uranus	5.100.596		Ice tears	Isaac shoots ice tears, which slow enemies and freeze monsters they kill. Frozen enemies slide away and explode into ice shards when touched.	3
Stop Watch	5.100.232		Let's slow this down a bit...	+0.3 speed. Automatically inflicts slow to all enemies in every room. +0.3 speed. Upon taking damage, inflicts slow to all enemies for the current room. +0.3 speed. Slows all enemies in every room to 80% speed.	4

Trinkets that slow enemies

Name	ID	Icon	Quote	Description
Locust of Famine	5.350.115		I bring Famine	Upon entering a room with enemies, spawns a Yellow Locust that damages and slows enemies.
Chewed Pen	5.350.130		It's leaking	Adds a chance to fire tears that slow enemies.

Cards that slow enemies

Name	ID	Icon	Message	Description
Era Walk	5.300.54		Savor the moment	For the current room, enemies are slowed, Isaac's speed is increased by 0.50, and his shot speed is decreased by 1.00.

Pills that slow enemies

Pill	Effect
I'm Drowsy...	Slows all enemies for the duration of the room. Slows all enemies, Isaac, and the background music for the duration of the room.

Notes

• The creep from items like Ball of Tar and Juicy Sack only slow enemies for as long as they remain in the creep.
• The Mask + Heart enemy is not affected by the slow effect.
• Stop Watch's slowdown effect is classified as a separate effect from the slow status and fully stacks with the status. See Stop Watch for more details.

Friendly

Activated items that create friendly enemies

Name	ID	Icon	Quote	Description	Quality
Friendly Ball	5.100.382		Gotta fetch 'em all!	Throwing the ball at a monster instantly kills and captures it. The captured enemy can later be released and will be friendly, fighting for Isaac and persisting between rooms.	1
Book of the Dead	5.100.545		Rise from the grave	Creates a friendly Bony, Black Bony, or an orbital bone for each enemy killed in the current room. Creates a friendly Bony, Black Bony, Bone Fly, Revenant, or an orbital bone for each enemy killed in the current room.	3
Delirious	5.100.510		Unleash the power!	Spawns Delirium as a random friendly boss that fights for Isaac.	1
Friend Finder	5.100.687		Best friends forever!	Spawns a random friendly monster that mimics Isaac's movements and attacks.	3

Passive items that create friendly enemies

Name	ID	Icon	Quote	Description	Quality
My Shadow	5.100.433		Me! And my shaaaadow!	Inflicts fear on all enemies in the room upon taking damage and spawns black friendly Chargers that attack enemies. Spawns a shadow familiar that closely follows behind Isaac. It spawns a black friendly Charger whenever an enemy touches it.	2
Mystery Egg	5.100.539		Sacrificial insemination	Spawns an egg familiar, which hatches a random friendly monster when Isaac is hurt once per room. The power of the monster improves for each consecutive room cleared without taking damage.	1
Poke Go	5.100.505		Gotta catch em...	Upon entering a room with enemies in it, has a chance to spawn a random friendly enemy that persists across rooms.	2
Shade	5.100.468		It follows	Spawns a shadow familiar that follows Isaac's movements on a 1 second delay and deals contact damage to enemies. After dealing enough damage, it is absorbed by Isaac and spawns friendly Chargers.	0

Trinkets that create friendly enemies

Name	ID	Icon	Quote	Description
Polished Bone	5.350.167		Friends from beyond	After clearing a room, adds a chance to spawn a friendly Bony.

Other sources to create friendly enemies:

• Beelzebub makes large fly enemies become friendly.

Shrink

Passive items that grant shrinking tears

Name	ID	Icon	Quote	Description	Quality
God's Flesh	5.100.398		Shrink shot!	Tears have a chance to shrink enemies, making them run away from Isaac. Shrunk enemies can be crushed and killed by walking over them.	1

Bleed

Passive items that inflict bleed

Name	ID	Icon	Quote	Description	Quality
Backstabber	5.100.506		Watch your back!	Isaac's tears deal double damage and inflict bleeding on enemies if they're facing away from Isaac.	3
Mom's Razor	5.100.508		It's sharp!	Spawns an orbiting razor that deals contact damage and inflicts bleeding on enemies, causing them to slowly take damage over time.	2

Bait

Passive items that inflict bait

Name	ID	Icon	Quote	Description	Quality
Rotten Tomato	5.100.618		Delicious!	Adds a chance to fire tears that mark enemies with the Bait status effect. Enemies marked as bait are attacked by other enemies.	2

Chained

Activated items that inflict chained

Name	ID	Icon	Quote	Description	Quality
Anima Sola	5.100.722		Repent	Chains down the nearest enemy for 5 seconds, preventing them from acting.	3

Frozen

Passive items that freeze enemies

Name	ID	Icon	Quote	Description	Quality
Cube Baby	5.100.652		Kick it!	Spawns an ice cube familiar that slides around when walked into. It slows and deals contact damage, freezing monsters it kills.	1
Freezer Baby	5.100.608		Iced iced baby	Spawns a shooting familiar that has a chance to petrify enemies, and freezes monsters upon killing them.	2
Uranus	5.100.596		Ice tears	Isaac shoots ice tears, which slow enemies and freeze monsters they kill. Frozen enemies slide away and explode into ice shards when touched.	3

Trinkets that freeze enemies

Name	ID	Icon	Quote	Description
Ice Cube	5.350.188		Stay frosty	Adds a chance to petrify enemies when entering the room. Killing the petrified enemy freezes it.

Random

These items inflict random status effects on enemies.

Passive items that inflict random effects

Name	ID	Icon	Quote	Description	Quality
3 Dollar Bill	5.100.191		Rainbow tears	Gives Isaac a random tear effect every room. Gives Isaac a random tear effect every few seconds.	2
Fruit Cake	5.100.418		Rainbow effects!	Isaac's tears gain a random effect that changes every shot.	2
Spider Mod	5.100.403		Mod buddy!	Displays Isaac's tear damage and enemy health bars. Spawns a familiar that wanders around and inflicts random status effects on enemies it touches. Can spawn a Lil' Battery/Blue spider upon clearing a room.	1
Playdough Cookie	5.100.570		Tasty rainbow	Grants multicolored tears. Each color comes with a different status or tear effect.	2
GB Bug	5.100.405		Double tap glitch	Spawns a familiar that bounces diagonally around the room, applying a random status effect to enemies it hits and has a chance to re-roll pickups it passes over. Spawns a familiar that follows Isaac. Double tapping the fire button launches it forward, causing it to reroll the first monster or pickup it hits.	1

Other sources that inflict random effects

• Spider Baby creates a spider familiar that applies random status effects to enemies that come in contact with it.

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