Mom's Key
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Mom's Key is a passive item.
Effects
- Gives Isaac two
Keys. - If a non-
Red Chest spawns hearts, coins, 
Bombs and/or Keys, causes the chest to spawn a second group of said pickups, effectively doubling the average pickup yield. 
This item belongs to the 
Yes Mother? set. Collecting three items from this set will transform Isaac into his mother.
Notes
- Mom's Key cannot change the contents of a chest; it will only cause it to spawn extra pickups.
- All other chest rewards (such as pills, cards, items, etc.) will not cause the chest to spawn additional pickups.
Does not affect 
Old Chests.
Synergies
Sharp Key: Doubles the amount of pickups dropped by enemies.
Interactions
Mom's Key: Does not further increase the amount of pickups spawned when multiple copies of the item are acquired.
In-game Footage
Trivia
- Mom's Key is the first item, by ID number, that was not carried over from Wrath of the Lamb.
- The appearance of Mom's Key is a reference to Bowser's boss key in Super Mario 64 as well as the Boss Key in various Legend of Zelda games.
Prior to Repentance, this item's description was "Less is now more +2 keys".
 Keys
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| Items |
| Trinkets |
| Cards and Runes |
 The Binding of Isaac: Rebirth
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