Chemical Peel
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Chemical Peel is a passive item.
Effects
- +2 flat damage to tears fired from Isaac's left eye.
Notes
- The damage bonus is unaffected by both positive and negative damage multipliers.
-
Cain has a 50% chance of firing a shot with the effects of Chemical Peel whenever he fires. 
Blood Clot applies to the same eye and the effects stack.
- Generally every interaction and synergy that applies to Chemical Peel also applies to Blood Clot. See its page for any differences to what is listed here.
Synergies
20/20/
The Inner Eye/
Mutant Spider: Every other set of tears has the Chemical Peel effect.
Brimstone: The entire laser has a high chance to have the Chemical Peel effect, with no visual difference.
Dr. Fetus: The damage bonus applies to every bomb, with no visual difference.
Epic Fetus: The missiles have a high chance to deal 40 points extra damage, with no visual difference.
Lead Pencil: All tears in the tear barrage will gain the Chemical Peel effect.
The Ludovico Technique: The tear flashes between normal and the higher-damaging Chemical Peel tear.
Mom's Knife: Each tick of the Knife's damage has a high chance to gain the bonus, with no visual difference.
Soy Milk: Chemical Peel is unaffected by Soy Milk's damage down modifier, greatly increasing DPS.
Tech.5: Chemical Peel has a chance to apply to the laser, with no visual difference.
Technology: Lasers have a high chance to gain extra damage, with no visual difference.
Technology 2: Every tear fired has Chemical Peel applied to it, but the laser is unaffected.
Interactions
Incubus: Has a 50% chance of firing a shot with the Chemical Peel effect.
Sad Bombs: The last type of tear fired is used for the burst.
Stapler: Gives a 50% chance of firing a Chemical Peel shot, similar to Cain.
Tech X: Overrides Chemical Peel.
Varicose Veins: The last type of tear fired is used for the burst.
In-game Footage
Trivia
- Isaac's face looks similar to a
Dople when this item is obtained. - Chemical Peel may be a reference to the DC Comics character Two-Face, who had the left side of his face burned by a chemical product in a way similar to the item costume effect
 The Binding of Isaac: Rebirth
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