Sacred Heart has the highest damage multiplier of all passive items.
The flat damage gained by Sacred Heart is not affected by its damage multiplier. However, other flat damage upgrades (such as those gained by Curved Horn or Void) will be affected normally.
Although Sacred Heart increases range, the reduction of shot speed results in a slight decrease in effective range, not accounting for homing.
Anti-Gravity: Tears will track enemies while frozen in place, once one gets close enough.
Sacred Heart: Picking up multiple copies of the item will only result in acquiring additional heart containers, while decreasing fire rate and shot speed.
The Sacred Heart (also known as the Most Sacred Heart of Jesus) is a devotion practiced in Catholicism, which represents "the heart of Jesus Christ God, pierced on the cross", and God's "boundless and passionate love for mankind".
+0.75 tear falling speed.
Bobby-Bomb).
This item belongs to the 
Seraphim set. Collecting three items from this set will transform Isaac into an angel.
Curved Horn or 
Void) will be affected normally.
Bag of Crafting with eight 
Eternal Hearts.
Anti-Gravity: Tears will track enemies while frozen in place, once one gets close enough.
Sacred Heart: Picking up multiple copies of the item will only result in acquiring additional heart containers, while decreasing fire rate and shot speed.
Tainted Bethany: On pickup, grants 12 blood charges.
