Replaces Isaac's right eye tears with an unlimited range piercing laser which fires continuously, dealing damage 15 times per second.
x0.65 Damage multiplier.
The laser deals 20% of Isaac's damage per tick.
This compounds with the damage down for a total of 13% of Isaac's damage per tick.
Only the laser deals 13% of Isaac's damage per tick.
Tears fired per second * (2/3).
Laser is able to knock back enemies.
Notes
Tear delay is effectively doubled, as Isaac will do a bit of the animation to fire a right eye tear, but no tear will come out.
This applies to items that replace Isaac's tears, such as Mom's Knife and Brimstone.
Charged shots are not affected by the effective tear delay down, as they don't use the alternative left eye/right eye fire scheme.
As Cain can only fire tears from his right eye, Technology 2 will replace his tears altogether unless he has Technology or a charged attack.
When used by Cain, or a character that is forced to fire from one eye due to the effects of Stapler or Lead Pencil, they will fire Technology lasers out of their right eye instead of their normal tears, as long as they have no other items that replace their tears (Neptunus lets them fire tears normally). These lasers cannot be angled with momentum.
Because Lilith is blindfolded and relies on her Incubus, the only effect gained from Technology 2 is the damage down.
Incubus can fire laser and tears as normal; stat effects apply.
The blood clots spawned by Tainted Eve will all also fire their own individual lasers.
The laser can apply status effects very efficiently due to its high tick rate.
Blood Clot / Chemical Peel: Since Isaac's right eye is replaced by Technology 2, he can only fire tears from his left eye, which gives all his tears higher damage and range.
Brimstone: Laser fires continuously while Brimstone charges at normal rate.
Chocolate Milk: The laser fires while Chocolate Milk charges at normal rate.
Cricket's Body / The Parasite: The laser will rapidly split into small low damage tears upon impact with an enemy or obstacle.
Cursed Eye: The laser fires while Cursed Eye charges at normal rate, retaining the teleporting effect.
Tears are replaced with lasers, fired from the same eye of Technology 2.
Epic Fetus: The laser fires while the missiles are being aimed.
Ipecac: Laser damage increases dramatically while also gaining the poison effect.
Lachryphagy: The laser has its range shortened but rapidly creates and feeds Lachryphagy tears.
Lead Pencil: Replaces tears with lasers similar to Technology. These are shot from the eye that shoots Technology 2, doing damage alongside the Technology 2 beam.
Lost Contact: The laser destroys all hostile projectiles that come into contact with it.
The Ludovico Technique: Isaac simultaneously controls a tear and fires the laser; however, Isaac will only fire the Technology 2 laser in the direction that the tear is currently facing.
The Ludovico Technique also makes the laser spectral.
A Lump of Coal: Damage increases the further away the enemy is, on a multiplier that is roughly +20% per tile of distance.
Marked: Isaac simultaneously controls a big red target on the ground and fires the laser in the cardinal directions.
The laser now continuously fires towards the crosshair along with tears.
Mom's Knife: The laser fires while the Knife charges at normal rate.
Monstro's Lung: The laser fires while Monstro's Lung charges at normal rate. No reduction in tear burst size.
Technology: Equips two lasers that can be fired at the same time. As Technology is always fired from the right eye, it is not affected by the halved normal attack rate.
Technology is affected by the fire rate multiplier. Holding Stapler, Lead Pencil or playing as Cain will allow Isaac to angle shots with momentum again.
Tiny Planet: The laser spirals around Isaac once and then goes straight again.
The Wiz: Tears are fired diagonally while the laser is fired straight forward.
Urn of Souls: Isaac can still fire the laser as normal while using the urn.
Interactions
Azazel: The Technology 2 continuously fires its lesser damage laser as Azazel charges his Brimstone.
Brimstone: Overrides Technology 2, but retains the reduced damage.
Technology 2 prevents Lead Pencil and normal tears from firing if collected with specific items.
Bug!
While playing as The Forgotten, holding fire as either The Forgotten or The Soul then switching to the other will create another Technology 2 laser in the direction being fired that persists until the room is left.
Bug!
If Isaac is holding fire and has The Ludovico Technique while pulling out Urn of Souls, another Technology 2 laser is created in the direction being fired that persists until the urn is put away or the room is left.
Bug!
Having Technology 2, Technology and Mom's Eye makes the back laser fire extremely fast.
x0.65 Damage multiplier.
Only the laser deals 13% of Isaac's damage per tick.
Mom's Knife and 
Brimstone.
Cain can only fire tears from his right eye, Technology 2 will replace his tears altogether unless he has 
Technology or a charged attack.
Stapler or 
Lead Pencil, they will fire 
Neptunus lets them fire tears normally). These lasers cannot be angled with momentum.
Lilith is blindfolded and relies on her 
Incubus, the only effect gained from Technology 2 is the damage down.
Tainted Eve will all also fire their own individual lasers.
8 Inch Nails / 
Blister / 
Pisces: The laser will consistently push back enemies.
Blood Clot / 
Chemical Peel: Since Isaac's right eye is replaced by Technology 2, he can only fire tears from his left eye, which gives all his tears higher damage and range.
Chocolate Milk: The laser fires while Chocolate Milk charges at normal rate.
Cricket's Body / 
The Parasite: The laser will rapidly split into small low damage tears upon impact with an enemy or obstacle.
Cursed Eye: The laser fires while Cursed Eye charges at normal rate, retaining the teleporting effect.
Epic Fetus: The laser fires while the missiles are being aimed.
Euthanasia / 
Explosivo / 
Holy Light / 
Little Horn / 
Nose Goblin / 
Sinus Infection: Every damage tick from the laser can also apply these tear effects and does so rapidly.
Lil Clot / 
Sumptorium / 
Twisted Pair: The familiars fire a continuous laser. 
Ipecac: Laser damage increases dramatically while also gaining the poison effect.
Lachryphagy: The laser has its range shortened but rapidly creates and feeds Lachryphagy tears.
Lost Contact: The laser destroys all hostile projectiles that come into contact with it.
The Ludovico Technique: Isaac simultaneously controls a tear and fires the laser; however, Isaac will only fire the Technology 2 laser in the direction that the tear is currently facing.
A Lump of Coal: Damage increases the further away the enemy is, on a multiplier that is roughly +20% per tile of distance.
Marked: Isaac simultaneously controls a big red target on the ground and fires the laser in the cardinal directions.
Monstro's Lung: The laser fires while Monstro's Lung charges at normal rate. No reduction in tear burst size.
Rubber Cement: Laser bounces off of walls.
Tiny Planet: The laser spirals around Isaac once and then goes straight again.
The Wiz: Tears are fired diagonally while the laser is fired straight forward.
Urn of Souls: Isaac can still fire the laser as normal while using the urn.
Azazel: The Technology 2 continuously fires its lesser damage laser as Azazel charges his Brimstone.
Sulfuric Acid: The laser is unaffected.
Eye of Belial / 
Parasitoid: The laser is unaffected.
Eye of the Occult: Only affects the laser's color.
Fire Mind: Tears still ignite enemies, but no longer have a chance to explode.
Isaac's Tears: Fires normal tears.
Mom's Eye: Occasionally shoots a laser behind Isaac. With 15+ Luck, fires a new laser on every tick, dealing extremely high damage.
My Reflection: Laser is bent in the opposite direction as Isaac moves sideways, then gradually becomes straight as he stands still.
Pop!: The laser has drastically reduced range, and eyeball tears are rapidly created at the end of the laser.
Soy Milk: Both damage reductions are applied, along with removing one eye's worth of tears.
Sprinkler: No effect.
Technology 2: Multiple copies of the item provide no benefit.
Bug!
The Forgotten, holding fire as either 
The Soul then switching to the other will create another Technology 2 laser in the direction being fired that persists until the room is left.
The Binding of Isaac: Rebirth
