Placed bombs deal damage to enemies on contact and will leave behind a fire that damages enemies on contact upon exploding for 10 seconds.
The fire does 22 damage per tick (66 damage per second).
The fire can block four shots and/or deal four ticks of contact damage before expiring. It deals 23 damage at full durability, 17.25 damage after taking one hit, and 11.5 damage otherwise for a maximum damage of 63.25 damage.
Fire from a Hot Bomb doesn't damage Isaac.
Bombs deal 1 point of contact damage to enemies.
Bombs deal 16 contact damage to enemies.
Isaac can no longer take contact damage from static fires such as Fire Places or enemy fires. Fire projectiles still damage Isaac.
The contact damage does not scale with Isaac's damage and is completely removed if Isaac acquires another bomb item that overrides the flaming bomb graphic such as Mr. Mega or Glitter Bombs.
Big Horn will throw Hot Bombs at Isaac that deal contact damage.
If eaten by a boss such as Chub, a Hot Bomb will continously deal damage to the boss until it explodes.
Negates the damage from the floor of lava in The Beast's chamber, but not from its fire inhalation attack.
Bombs on pickup.
The fire does 22 damage per tick (66 damage per second).
The fire can block four shots and/or deal four ticks of contact damage before expiring. It deals 23 damage at full durability, 17.25 damage after taking one hit, and 11.5 damage otherwise for a maximum damage of 63.25 damage.
Hopper touches a Hot Bomb, it will become a 
Flaming Hopper.
Mr. Mega or 
Glitter Bombs.
Big Horn will throw Hot Bombs at Isaac that deal contact damage.
Chub, a Hot Bomb will continously deal damage to the boss until it explodes.
The Beast's chamber, but not from its fire inhalation attack.
BBF / 
Best Friend / 
Bob's Brain / 
Bob's Rotten Head / 
Mr. Boom: These explosions are affected by Hot Bombs.
Bomber Boy: Bombs leave behind nine fires in a cross shaped pattern.
Doctor's Remote / 
Dr. Fetus / 
Epic Fetus: Bombs/missiles are affected by Hot Bombs.
Remote Detonator: Allows for maximization of contact damage, especially if an enemy gets stuck on a bomb.
Scatter Bombs: Each additional explosion creates a fire.
Ipecac: Ipecac shots are unaffected.
Little Horn summons bombs that are identical in function, but given the 
Troll Bomb sprite and colored orange.
Bombs 
The Binding of Isaac: Rebirth
