Experimental Treatment

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Experimental Treatment is an unlockable passive item.

Effects

  • (in Rebirth and Afterbirth) Randomly increases at least 1 and decreases 1-3 of Isaac's stats. The same stats can be increased/decreased multiple times.
  • (except in Rebirth and Afterbirth) Randomly increases 4 and decreases 2 of Isaac's stats.
  • Each increase or decrease for a stat will change it by a fixed value:
  • If a stat that is already at an upper or lower limit is chosen, there is no visible effect.
  • (except in Rebirth) This item belongs to the SpunSpun set. Collecting three items from this set will transform Isaac into a buff berserker.

Notes

The stat changes are permanent and will not go away if the item is removed.

  • (in Repentance and Repentance+) This makes the item especially useful for (in Repentance and Repentance+) Character Tainted Isaac icon.pngTainted Isaac, since he gets to keep the stats while having the option to switch Experimental Treatment for another item and the transformation progress isn't lost in the process.

(in Repentance and Repentance+) The tears up from this item is allowed to go past the normal tear cap of 5.0. However if it decreases tears, the normal tear cap will also be decreased.

In-game Footage

Unlockable Achievements

Trivia

(except in Repentance and Repentance+) Prior to Repentance, this item's description was "All stats up... then shuffled".

  • Despite the item's old description, the item did not increase all stats or shuffle them.

Gallery