The Binding of Isaac: Afterbirth †

From The Binding of Isaac: Rebirth Wiki
(Redirected from Afterbirth †)
Jump to navigation Jump to search
(in Afterbirth †)

Afterbirth † is an expansion to The Binding of Isaac: Afterbirth that was released on January 3, 2017 and costs $9.99.

For a list of the pre-release blog posts, see The Binding of Isaac: Afterbirth † (Pre-Release).

Nicalis, the game's publisher, also created mod tools for easier creation of community mods with the release. They occasionally released updates to Afterbirth † that incorporated certain high-quality and popular mods. These updates are known as Booster Packs.

Features

Additions

Mechanics

HUD

Found HUD
  • Found HUD is a HUD addition that appears on the left side of the screen that gives numerical values to the player's current stats (e.g., damage, luck, speed, devil room chance). It can be enabled through the options menu.
  • It is based on the Missing HUD mod for Rebirth and Afterbirth.

Victory Lap

  • A Victory Lap allows you to start a new run with almost all of your final items after completing the Dark Room. Multiple laps can be made as long as the Dark Room is cleared each time.
    • Completion Marks and most achievements cannot be earned.
    • Isaac will take a full heart of damage on all floors after beginning a victory lap (unless he has The Wafer).
    • Some items are lost upon starting a victory lap. Items lost this way are added back into their respective item pools and can be acquired again.
    • If the initial run was on normal difficulty, all victory laps will be on hard difficulty.
    • On the third and subsequent victory laps, the character will turn into The Lost. This version of The Lost does not get a Holy Mantle or D4. However, if the run was started as The Lost (or if the Holy Mantle was found) it is possible to keep the Holy Mantle from the previous run.
    • On the third and subsequent victory laps, Shops will no longer appear.
    • On the third and subsequent victory laps, Red Chests in the Dark Room will turn into Chests and Locked Chests.
    • Killing any final boss aside from The Lamb will end the game, and the run will not be continued further.

Menus

Options

Charge bars
RERUN
  • RERUN is unlocked after completing the RERUN achievement.
  • After winning a run the Continue option in the main menu will be replaced by Rerun. Selecting it starts a new run using most of the previous won run's items. Isaac will take full heart damage on all floors.

Player

Characters

Character Character Apollyon appearance.png
Character Apollyon icon.pngApollyon
Character The Forgotten appearance.png
Character The Forgotten icon.pngThe Forgotten
The Forgotten Character The Soul (Character) icon.pngThe Soul
Health Stat Icon.png Health Full red heartFull red heart Full bone heartFull bone heart Full soul heart
Damage Stat Icon.png Damage 3.5 (*1.00) 3.50 (*1.50) 3.50 (*1.00)
Tears Stat Icon.png Tears +0 +0, x1/2 +0
Shot Speed Stat Icon.png Shot Speed 1 1 1
Range Stat Icon.png Range 23.75 23.75 23.75
Speed Stat Icon.png Speed 1.0 1.00 1.30
Luck Stat Icon.png Luck 0 0 0
Starting Item Icon.png Starting Pickups None None None
Starting Item Icon.png Starting Item(s) Collectible Void Afterbirth+ icon.pngVoid Bone Club Flight

Spectral tears

Transformations

ID Name Appearance Description
10 Bookworm Bookworm

Roughly 25% of the time, Isaac shoots an extra tear, like Collectible 20 20 icon.png20/20.

11 Adult Adult

+1 Red Heart container.

12 Spider Baby Spider Baby

Spawns a spider familiar that applies random status effects to enemies it comes in contact with.

13 Stompy Stompy

Taking damage has a chance to spawn rock waves. (in Repentance and Repentance+) Isaac can break obstacles by walking over them.

Co-op

Special Babies

These Babies have special bonuses that will aid the player in some way.

ID Appearance Name Description
55 055 baby mort.png Mort Baby Spawns a blue fly, and spawns a new blue fly whenever its blue fly is destroyed.
Mort Baby Defeat Mega Satan as Character Apollyon icon.pngApollyon to unlock it. The sprite greatly resembles Collectible Rotten Baby icon.pngRotten Baby.
56 056 baby apollyon.png Apollyon Baby Spawns with two Pretty Flies.
Apollyon Baby Earn all Hard mode Completion Marks as Character Apollyon icon.pngApollyon to unlock it.
57 057 baby boner.png Bone Baby Wields a melee bone club instead of shooting tears, similarly to The Forgotten.
Bone Baby Earn all Hard mode Completion Marks as Character The Forgotten icon.pngThe Forgotten to unlock it.
58 058 baby bound.png Bound Baby Is bound to Isaac, similarly to The Forgotten's soul. Shoots spectral tears.
Bound Baby Defeat Mega Satan as Character The Forgotten icon.pngThe Forgotten to unlock it.

Normal Babies

These Babies are purely cosmetic and do not have any special behaviors.

ID Appearance Name Description
428 428 baby magiccat.png Magiccat Baby A baby that resembles the avatar of Tikara, the artist of the Isaac Tarot deck.
429 429 baby littlehorn.png Little Horn Baby A baby that resembles Little Horn.
430 430 baby folder.png Folder Baby A baby with a folder for a head.
431 431 baby driver.png Driver Baby A baby that is driving a car.
432 432 baby dragon.png Dragon Baby A baby that resembles a dragon.
433 433 baby downwell.png Downwell Baby A baby that resembles the player character from Downwell.
434 434 baby cylinder.png Cylinder Baby A baby that is shaped like a cylinder.
435 435 baby cup.png Cup Baby A baby with a teacup for a head.
436 436 baby cave robot.png Cave Robot Baby A baby that resembles Quote from Cave Story.
437 437 baby breadmeat hoodiebread.png Breadmeat Hoodiebread Baby A toothy baby with a slice of toast for a head that resembles Breadmeat, a member of the Isaac community.
438 438 baby bigmouth.png Bigmouth Baby A baby with a large, wide-open mouth.
439 439 baby afro rainbow.png Afro Rainbow Baby A baby with a rainbow colored afro.
440 440 baby afro.png Afro Baby A baby with an afro.
441 441 baby tv.png TV Baby A baby with a television for a head.
442 442 baby tooth.png Tooth Baby A baby with a tooth for a head.
443 443 baby tired.png Tired Baby A tired-looking baby.
444 444 baby steroids.png Steroids Baby A muscular baby.
445 445 baby soap monster.png Soap Monster Baby A baby that resembles Balrog from Cave Story.
446 446 baby rojen whitefox.png Rojen Whitefox Baby A baby that resembles a white fox. (might be a reference?)
447 447 baby rocket.png Rocket Baby A baby that looks like a firework.
448 448 baby nurf.png Nurf Baby A baby that resembles D.Va from Overwatch.
449 449 baby mutated fish.png Mutated Fish Baby A baby that resembles Fish from Nuclear Throne.
450 450 baby moth.png Moth Baby A baby that resembles Moth from Creepy Castle.
451 451 baby buttface.png Buttface Baby A baby with a butt for a face.
452 452 baby flying candle.png Flying Candle Baby A baby that looks like a candle.
453 453 baby graven.png Graven Baby A baby with long hair. (might be a reference?)
454 454 baby gizzy chargeshot.png Gizzy Chargeshot Baby A baby that resembles Gizzy from ChargeShot.
455 455 baby green koopa.png Green Koopa Baby A baby that resembles a green koopa from Mario.
456 456 baby handsome mrfrog.png Handsome MrFrog Baby A baby that resembles Handsome Mr. Frog from the game of the same name.
457 457 baby pumpkin guy.png Pumpkin Guy Baby A baby with a pumpkin for a head wearing a purple rag. Possible reference to Terraria's Pumpking.
458 458 baby red koopa.png Red Koopa Baby A baby that resembles a red koopa from Mario.
459 459 baby sad bunny.png Sad Bunny Baby A baby that looks like a crying rabbit. This is a reference to the sprites creator, Mort Mort (MnrArt) and their character Sad Bunny Face.
460 460 baby saturn.png Saturn Baby A baby that resembles the main character from Sgt. Saturn.
461 461 baby toast boy.png Toast Boy Baby A baby with a slice of bread for a head. This is a reference to the sprite's creator, Mort Mort (MnrArt) and their character Toast Boy.
462 462 baby voxdog.png Voxdog Baby A baby that resembles Vox the Dog.
463 463 baby 404.png 404 Baby A baby that has the Error trinket for a head.
464 464 baby arrowhead.png Arrowhead Baby A baby with an arrow through its head.
465 465 baby beanie.png Beanie Baby A baby wearing a green beanie.
466 466 baby blindcursed.png Blindcursed Baby A baby with the Curse of the Blind's question mark for a head.
467 467 baby burning.png Burning Baby A baby that's been burnt to a crisp.
468 468 baby cursor.png Cursor Baby A baby that looks like a mouse cursor.
469 469 baby flybaby.png Flybaby A baby that looks like a fly.
470 470 baby headphone.png Headphone Baby A baby wearing headphones.
471 471 baby knife.png Knife Baby A baby with a knife for a head.
472 472 baby mufflerscarf.png Mufflerscarf Baby A baby wearing a scarf.
473 473 baby robbermask.png Robbermask Baby A baby wearing a stereotypical robber's ski mask.
474 474 baby scoreboard.png Scoreboard Baby A baby with a digital number display, like those at a sporting event or on an alarm clock, for a face.
475 475 baby somanyeyes.png So Many Eyes Baby A baby with eyes all over its body.
476 476 baby text.png Text Baby A baby made out of text characters. (ASCII art)
477 477 baby wing.png Wing Baby A baby with wings.
480 480 baby imp.png Imp Baby A baby that resembles the modded character Fiend from Devil's Harvest MOD.
481 481 baby 32bit.png 32bit Baby A baby that resembles Isaac in a 32 bit style.
482 482 baby adventure.png Adventure Baby A baby that resembles Finn the Human from Adventure Time.
483 483 baby bubbles.png Bubbles Baby A baby made entirely of tar.
484 484 baby bulb.png Bulb Baby A baby that's very bright for his age.
485 485 baby coolorange.png Cool Orange Baby A baby that resembles a very cool orange with sunglasses.
486 486 baby crazyghost.png Crazy Ghost Baby A baby that resembles Crazy Diamond from JoJo's Bizarre Adventure. (Also possibly a reference to the modded character.)
487 487 baby cursedpillow.png Cursed Pillow Baby A baby that's unfortunately pillow shaded.
488 488 baby egg.png Egg Baby A baby that resembles the modded item Greg the Egg.
489 489 baby factory.png Factory Baby A baby that resembles a strange cyborg.
490 490 baby falling.png Falling Baby A baby that resembles William Foster from Falling Down.
491 491 baby funny.png Funny Baby A baby that resembles Sans from Undertale.
492 492 baby gamer.png Gamer Baby A baby that resembles an epic gamer. Inspired by a prominent member of the Binding of Isaac community.
493 493 baby glitterypeach.png Glittery Peach Baby A baby resembling an oddly British Baby Plum.
494 494 baby pompadour.png Pompadour Baby A baby that resembles Josuke from JoJo's Bizarre Adventure. (Also possibly a reference to the modded character.)
495 495 baby headkick.png Head Kick Baby A baby that resembles the Facepunch Logo.
496 496 baby horn.png Horn Baby A baby that resembles the modded character Chronos.
497 497 baby ichor.png Ichor Baby A baby that resembles Ichor beasts from the game Heckland.
498 498 baby ill.png Ill Baby A baby that resembles the modded boss Mahalath.
499 499 baby lazy.png Lazy Baby A baby that resembles Garfield.
500 500 baby mern.png Mern Baby Mern.
501 501 baby necro.png Necro Baby A baby that resembles the Xenomorph from the Alien franchise.
502 502 baby peeping.png Peeping Baby A baby that resembles the modded boss The Peeping.
503 503 baby penance.png Penance Baby A baby that resembles the modded character Sarah from Revelations.
504 504 baby psychic.png Psychic Baby A baby that resembles the modded character Mei.
505 505 baby puppet.png Puppet Baby A baby that resembles the costume for the modded item Pinhead from Happy Items Pack.
506 506 baby reaper.png Reaper Baby A baby that resembles the modded character Samael.
507 507 baby roadkill.png Road Kill Baby A baby that got ran over.
508 508 baby sausagelover.png Sausage Lover Baby A baby that resembles _Kilburn, the lead developer for Antibirth.
509 509 baby scribble.png Scribble Baby A baby that resembles the modded character The Drawn.
510 510 baby starplant.png Star Plant Baby A baby that resembles the main character from Germination.
511 511 baby twitchy.png Twitchy Baby A baby that resembles Twitch from Heckland.
512 512 baby witch.png Witch Baby A baby that resembles the modded character Endor from Alphabirth.
513 513 baby workshop.png Workshop Baby A baby that references a common trope of workshop thumbnails when firing tears.
514 514 baby hooligan.png Hooligan Baby A baby that resembles Čeda from LeatherIceCream's "Poor 4" animations.
515 515 baby halfspider.png Half Spider Baby A baby that resembles Miroslav from LeatherIceCream's "Poor 4" animations.
516 516 baby silly.png Silly Baby A baby that resembles Djole from LeatherIceCream's "Poor 4" animations.
517 517 baby mastercook.png Master Cook Baby A baby that resembles Andre from LeatherIceCream's "Poor 4" animations.
518 518 baby greenpepper.png Green Pepper Baby A baby that resembles one of _Kilburn's characters.
519 519 baby baggycap.png Baggy Cap Baby A baby that resembles one of _Kilburn's characters.
520 520 baby stylish.png Stylish Baby A baby resembling the character Ren from the currently unreleased game Shenanigans: World of Illusions.



Items

109 new items were added in the expansion: 29 activated items and 80 passive items.

Activated Collectibles

Name ID Icon Quote Description Quality
Black Hole 5.100.512
Black Hole
4 rooms
Nothing can escape Throws a black hole on the ground which sucks in and damages enemies and destroys nearby obstacles.
1
Book of the Dead 5.100.545
Book of the Dead
6 rooms
Rise from the grave (except in Repentance and Repentance+) Creates a friendly Bony.pngBony, Black Bony.pngBlack Bony, or an orbital bone for each enemy killed in the current room.
(in Repentance and Repentance+)Creates a friendly Bony.pngBony, Black Bony.pngBlack Bony, Bone Fly.pngBone Fly, Revenant.pngRevenant, or an orbital bone for each enemy killed in the current room.
2
Broken Shovel 5.100.550
Broken Shovel
4 rooms
It feels cursed While held, causes Mom to continuously attempt to stomp on Isaac. Activating makes her stop for the current room or wave. One of two parts necessary to create Collectible Mom's Shovel icon.pngMom's Shovel.
4
Brown Nugget 5.100.504
Brown Nugget
8 seconds
Friendly fly Spawns a stationary fly turret that lasts for the current room and fires tears at nearby enemies.
0
Clicker 5.100.482
Clicker
6 rooms
Change Transforms Isaac into another random character and removes the last item collected.
0
Compost 5.100.480
Compost
2 rooms
Gain more friends! Doubles Isaac's Blue Flies and Blue Spiders, or spawns one if Isaac has none. Converts pickups in the current room into Blue Flies or Blue Spiders.
0
Coupon 5.100.521
Coupon
6 rooms
Allow 6 weeks for delivery While held, guarantees one item in every ShopShop will be on sale for half price. On use, makes a random item in the current room free.
2
Crooked Penny 5.100.485
Crooked Penny
4 rooms
50/50 Has a 50% chance to double all items, chests, and pickups in the room. If the effect fails, spawns a Penny.pngPenny and the other items and pickups disappear.
2
D infinity 5.100.489
D infinity
Variable
Reroll forever (except in Repentance and Repentance+) Has the effect of a random die item that changes each use.
(in Repentance and Repentance+) Replicates the effect of almost any die item, and can be cycled through by pressing the drop key.
4
D1 5.100.476
D1
4 rooms
What will it be? Duplicates a random pickup in the room. (in Repentance and Repentance+) The new pickup may be different than the original (i.e. a different card, etc).
2
Dataminer 5.100.481
Dataminer
4 rooms
109 Displaces enemy sprites for the current room and randomly increases one of Isaac's stats while decreasing another. (in Repentance+) Turns all items in the room into glitched items with random effects.
0
Delirious 5.100.510
Delirious
Variable
Unleash the power! Spawns Boss Delirium ingame.pngDelirium as a random friendly boss that fights for Isaac. (except in Repentance+) The boss lasts the for the current room. (in Repentance+) The boss persists between rooms. The charge time is based on the power of the boss summoned.
1
Dull Razor 5.100.486
Dull Razor
2 rooms
I feel numb... Hurts Isaac without depleting health, activating any items that trigger upon taking damage.
0
Eden's Soul 5.100.490
Eden's Soul
12 rooms
... Spawns two random items from the current room's Item Pool and then disappears. Starts with no charges.
3
Mama Mega! 5.100.483
Mama Mega!
One time use
BOOOOOOOOOM! Deals immense damage to all enemies, opens all bombable doors, and destroys all obstacles in the room. The effect occurs every time a new room is entered for the rest of the floor.
3
Metronome 5.100.488
Metronome
2 rooms
Waggles a finger Grants a random item effect for the current room.
1
Mom's Shovel 5.100.552
Mom's Shovel
4 rooms
Lost but not forgotten Creates a trapdoor that leads to the next floor. Unlocks Character The Forgotten icon.pngThe Forgotten when used on a mound of dirt that appears in Dark RoomDark Room.
4
Moving Box 5.100.523
Moving Box
4 rooms
Pack and unpack If the box is empty, picks up items and pickups in a room and stores them. If the box is not empty, places all stored items and pickups in the current room. (in Repentance and Repentance+) Can carry up to 10 items or pickups at once.
1
Mr. ME! 5.100.527
Mr. ME!
4 rooms
Caaan do! Summons a controllable ghost that can perform various tasks depending on what it targets.
3
Mystery Gift 5.100.515
Mystery Gift
One time use
Wrapped up nice for you! Spawns a random item from the current room's item pool, with a chance to spawn Collectible A Lump of Coal icon.pngA Lump of Coal or Collectible The Poop icon.pngThe Poop instead.
3
Pause 5.100.478
Pause
2 rooms
Stop! Freezes all enemies until a fire button is pressed.
Plan C 5.100.475
Plan C
One time use
My last resort Kills all enemies in the room, then kills Isaac three seconds later.
0
Potato Peeler 5.100.487
Potato Peeler
Unlimited
A pound of flesh Removes a Heart Container, increases damage and range, and grants a Collectible Cube of Meat icon.pngCube of Meat.
2
Sacrificial Altar 5.100.536
Sacrificial Altar
One time use
He demands a sacrifice Sacrifices up to two familiars and spawns an item pedestal for each familiar sacrificed. Converts all friendly spiders and flies into coins.
1
Sharp Straw 5.100.507
Sharp Straw
10 seconds
More blood! (except in Repentance and Repentance+) Damages all enemies in the room. Has a chance to drop a Half Red Heart.pngHalf Red Heart or Half Soul Heart.pngHalf Soul Heart if an enemy is hit.
(in Repentance and Repentance+) Damages all enemies in the room. Has a chance to drop a Half Red Heart.pngHalf Red Heart if an enemy is hit.
2
Smelter 5.100.479
Smelter
6 rooms
Trinket melter! Consumes Isaac's currently held trinket and applies its effects permanently.
2
Sprinkler 5.100.516
Sprinkler
4 rooms
Sprinkles. Creates a stationary sprinkler for the current room that rotates and fires tears in 8 directions. The tears copy Isaac's stats and most tear effects.
1
Telekinesis 5.100.522
Telekinesis
7 seconds
Power of the mind Any enemy shots that come near Isaac for the next three seconds are held in place then fired back.
1
Void 5.100.477
Void
4 rooms
Consume Consumes all pedestal items in the room. Activated items will have their effects added to Void, and passive items will grant random stat upgrades.
3
Wait What? 5.100.484
Wait What?
10 seconds
I can't believe it's not butter bean! Isaac farts, sending out a circular rock wave that destroys obstacles and hurts enemies.
1

Passive Collectibles

Name ID Icon Quote Description Quality
7 Seals 5.100.526 7 Seals Lil harbingers! Spawns a random Harbinger familiar that changes every 10 seconds. Harbingers have different behaviors and spawn themed Locusts.
2
Acid Baby 5.100.491 Acid Baby Pills pills pills! Spawns a familiar that drops a random pill every 3 rooms. Upon using a pill, all enemies in the room are poisoned.
2
Adrenaline 5.100.493 Adrenaline Panic = power Increases damage based on how many empty Red Heart containers Isaac has.
1
Analog Stick 5.100.465 Analog Stick 360 tears! +0.35 tears up. Allows Isaac to fire tears diagonally.
2
Angelic Prism 5.100.528 Angelic Prism Eclipsed by the moon Spawns an orbital familiar with a large orbital radius. Tears that pass through the prism split into four multi-colored tears.
3
Angry Fly 5.100.511 Angry Fly He's violent Spawns a fly familiar that orbits around a random enemy and deals 30 damage per second to enemies it comes in contact with.
1
Apple! 5.100.443 Apple! Trick or treat? +0.3 tears. Adds a chance to fire a razor blade that deals 4× Isaac's damage.
3
Backstabber 5.100.506 Backstabber Watch your back! Isaac's tears deal double damage and inflict bleeding on enemies if they're facing away from Isaac.
3
Belly Button 5.100.458 Belly Button What's in there? Drops a random trinket. Grants a second trinket slot.
2
Big Chubby 5.100.473 Big Chubby Chub chub Spawns a familiar that follows Isaac and charges across the room when Isaac fires, blocking shots and dealing 40.5 damage per second on contact.
1
Blanket 5.100.535 Blanket You feel Safe Grants one Soul Heart.pngSoul Heart. Upon entering a boss room, grants a shield that blocks one hit, then disappears.
2
Bloodshot Eye 5.100.509 Bloodshot Eye Bloody friend (except in Repentance and Repentance+) Spawns an orbital familiar that deals contact damage and fires a tear every 2 seconds.
(in Repentance and Repentance+) Spawns an orbital familiar that deals contact damage, blocks shots, and fires tears at enemies in its line of sight.
1
Bozo 5.100.513 Bozo Party time! +0.1 flat damage, grants a Soul Heart.pngSoul Heart. Enemies can randomly become briefly charmed or feared. Taking damage has a chance to spawn a Rainbow Poop.pngRainbow Poop.
2
Brittle Bones 5.100.549 Brittle Bones Everything hurts Replaces all Red Heart.pngRed Heart Containers with 6 empty Bone Heart.pngBone Hearts. (except in Repentance and Repentance+) Upon losing a Bone Heart, Isaac fires bones in 8 directions and permanently gains a tears up. (in Repentance and Repentance+) Upon losing a Bone Heart, Isaac fires bones in 8 directions and permanently gains a fire rate up.
3
Broken Modem 5.100.514 Broken Modem Lag! Enemies, enemy shots, tears, and pickups will briefly freeze in place at random intervals. The reward from clearing a room will sometimes be duplicated.
3
Broken Shovel 5.100.551 Broken Shovel It feels cursed One of two parts necessary to create Collectible Mom's Shovel icon.pngMom's Shovel. No effect if somehow obtained on its own.
4
Buddy in a Box 5.100.518 Buddy in a Box What could it be?! Spawns a familiar with a random tear effect. The familiar is randomized at the start of each floor.
2
Camo Undies 5.100.497 Camo Undies Camo kid Isaac becomes camouflaged at the beginning of each room. Until he shoots, all non-boss enemies will be confused. (in Repentance and Repentance+) Isaac gains +0.5 Speed while camouflaged, and gains Tears and Damage upon breaking it.
3
Compound Fracture 5.100.453 Compound Fracture Bone tears! Increases Range. Tears turn into bones, which shatter into 1-3 bone shards upon hitting an enemy or obstacle.
3
Cone Head 5.100.457 Cone Head Hard headed! Grants a Soul Heart.pngSoul Heart. Gives Isaac a chance to ignore any damage taken.
2
Contagion 5.100.466 Contagion Outbreak! The first enemy killed in a room releases a gas cloud that poisons nearby enemies. Affected enemies will also release gas upon death, spreading the effect.
2
Dad's Lost Coin 5.100.455 Dad's Lost Coin I remember this... (except in Repentance and Repentance+)+1.5 range, +1 tear falling speed. Drops a Lucky Penny.
(in Repentance and Repentance+)+2.5 range. Drops a Lucky Penny.
1
Dad's Ring 5.100.546 Dad's Ring Father's blessing Creates a ring of light around Isaac that petrifies enemies in contact.
2
Dark Prince's Crown 5.100.442 Dark Prince's Crown Loss is power (except in Repentance and Repentance+) When at exactly one Red Heart.pngRed Heart, +0.75 tears, +1.5 range, and +0.2 shot speed.
(in Repentance and Repentance+) When at exactly one Red Heart.pngRed Heart, +2 fire rate, +1.5 range, and +0.2 shot speed.
1
Dead Tooth 5.100.446 Dead Tooth Toxic breath While firing, Isaac gains a green aura that poisons nearby enemies.
1
Death's List 5.100.530 Death's List Just hope you're not next... Grants a pickup or stat upgrade if all enemies in a room are killed in the order they are marked.
1
Depression 5.100.469 Depression :( Spawns a familiar that leaves a trail of creep that damages enemies at 6 damage per second. Has a chance to spawn damaging beams of light onto enemies that touch the cloud.
1
Divorce Papers 5.100.547 Divorce Papers Tears up + you feel empty Grants one Bone Heart.pngBone Heart, +0.7 tears, spawns a Mysterious PaperMysterious Paper.
3
Dog Tooth 5.100.445 Dog Tooth Bark at the moon! +0.3 damage, +0.1 speed. Plays a howl or bark sound when entering a room with undiscovered Secret RoomSecret Rooms or Crawl SpaceCrawl Spaces.
2
Duality 5.100.498 Duality You feel very balanced Whenever a Devil RoomDevil Room or Angel RoomAngel Room would spawn after defeating a boss, both rooms spawn. Only one can be entered.
1
Eucharist 5.100.499 Eucharist Peace be with you An Angel RoomAngel Room will always spawn after every boss fight, excluding the first floor and floors after Chapter 4.
3
Euthanasia 5.100.496 Euthanasia Needle shot Adds a luck-based chance to fire needles that instantly kill basic enemies and deal triple damage to bosses. If a needle kills an enemy, it bursts into more tears/needles.
3
Eye of Belial 5.100.462 Eye of Belial Possessed tears! Grants piercing tears. After piercing one enemy, tears start homing and deal double damage.
3
Eye of Greed 5.100.450 Eye of Greed Gold tears! Every 20 tears, Isaac loses 1 Penny.pngPenny and shoots an additional gold tear that petrifies enemies and turns them into gold. Any enemy killed while in this state will drop coins.
2
Fast Bombs 5.100.517 Fast Bombs Rapid bomb drops +7 Bomb.pngBombs. Removes the delay between bomb placements, allowing them to be placed rapidly. (in Repentance and Repentance+) Bombs will no longer knock each other away.
1
Finger! 5.100.467 Finger! Watch where you point that! Spawns a finger familiar that faces in the same direction as Isaac, rapidly damaging enemies it points at for 10% of Isaac's damage.
1
Flat Stone 5.100.540 Flat Stone Skipping tears Tears bounce off the floor, creating splashes. Splashes deal 25% of Isaac's tear damage to all enemies in a small area.
2
Ghost Pepper 5.100.495 Ghost Pepper Flame tears (except in Repentance and Repentance+)Gives a chance to shoot fires alongside tears that block enemy shots and deal damage to enemies that touch them.
(in Repentance and Repentance+)Gives a chance to shoot blue fires alongside tears that become smaller as they travel.
3
Glaucoma 5.100.460 Glaucoma Blind tears! Adds a chance to shoot tears that confuse enemies for an extremely long time.
1
Glyph of Balance 5.100.464 Glyph of Balance A gift from above Grants 2 Soul Heart.pngSoul Hearts and modifies drops from Champion monsters based on certain conditions. (in Repentance and Repentance+) Also modifies room clear drops.
2
Greed's Gullet 5.100.501 Greed's Gullet Money = health! Grants a Red Heart container for every 25 Penny.pngCoins Isaac has.
1
Haemolacria 5.100.531 Haemolacria I'm seeing red... Turns Isaac's tears into large blood tears fired in an arc. Upon hitting the floor, an obstacle, or an enemy, they burst into many smaller tears in all directions. Increases tear delay.
4
Hallowed Ground 5.100.543 Hallowed Ground Portable sanctuary Spawns a white poop familiar, which turns into a White Poop.pngWhite Poop when Isaac is hurt. White poop has an aura that increases tear fire rate and can block enemy shots. (in Repentance and Repentance+) The aura also increases damage by 20% and gives homing.
1
Hushy 5.100.470 Hushy Lil hush! Spawns a Boss Hush ingame.pngHush familiar that bounces diagonally around the room and deals contact damage. While firing tears, it stops moving. (in Repentance+) When stationary, Hushy will periodically fire out rings of projectiles.
0
Jacob's Ladder 5.100.494 Jacob's Ladder Electric tears Tears fire sparks of electricity in random directions upon hitting an obstacle or enemy.
3
Jaw Bone 5.100.548 Jaw Bone Fetch! Spawns a familiar that flies through the room while firing, dealing a flat 7 contact damage to enemies and retrieving pickups.
1
Jumper Cables 5.100.520 Jumper Cables Bloody recharge Grants an active item charge every 15 enemies killed.
3
King Baby 5.100.472 King Baby Hail to the king baby Spawns a familiar that follows Isaac and makes other familiars follow it. While firing tears, other familiars stop moving.
1
Lachryphagy 5.100.532 Lachryphagy Feed them! Isaac's tears decelerate as they travel. Upon stopping or hitting an obstacle, they burst into 8 tears in all directions. Tears can be fired into other tears to feed them, increasing their damage.
3
Large Zit 5.100.502 Large Zit Creep shots Adds a chance to fire a creep shot that deals double damage and leaves a trail of slowing white creep.
1
Lead Pencil 5.100.444 Lead Pencil He's a bleeder! After every 15 tears fired, Isaac will fire a high-damage cluster of tears.
3
Leprosy 5.100.525 Leprosy You're tearing me apart! Taking damage grants a body part orbital that blocks shots and deals contact damage, up to a maximum of three. The body parts are destroyed after blocking enough damage.
0
Lil Delirium 5.100.519 Lil Delirium Delirious friend Grants a familiar that transforms into another random familiar every 10 seconds.
1
Lil Monstro 5.100.471 Lil Monstro Ain't he cute? Spawns a familiar that fires clusters of tears. Must be charged before shooting.
2
Lil Spewer 5.100.537 Lil Spewer Puking buddy Drops a random pill, and spawns a familiar that charges up and fires creep. Using pills changes the creep type.
1
Linger Bean 5.100.447 Linger Bean Crying makes me toot Constantly shooting causes Isaac to release gas clouds that can be pushed by his tears and damage nearby enemies. (in Repentance+) The cloud will gradually increase in size, while the damage it does gradually decreases.
0
Little Horn 5.100.503 Little Horn Big brother is watching (except in Repentance and Repentance+) Adds a chance to fire a piercing tear that instantly kills any enemy that it touches.
(in Repentance and Repentance+) Adds a chance to fire a tear that summons Big Horn's hand to crush the first enemy it hits, instantly killing monsters or greatly damaging bosses.
3
Marbles 5.100.538 Marbles Choking hazard Spawns 3 random trinkets. Taking damage has a 5% chance to swallow Isaac's currently held trinket, gaining its effect permanently.
2
Marrow 5.100.541 Marrow HP up? Grants one Bone Heart.pngBone Heart and spawns three Red Heart.pngRed Hearts.
1
Metal Plate 5.100.449 Metal Plate It itches... Grants one Soul Heart.pngSoul Heart. Enemy shots have a chance to be reflected at the shooter as confusing tears.
1
Midnight Snack 5.100.456 Midnight Snack HP up Grants one full Red Heart container. (in Repentance and Repentance+) Heals 1 additional Red Heart.pngRed Heart.
1
Mom's Razor 5.100.508 Mom's Razor It's sharp! Spawns an orbiting razor that deals contact damage and inflicts bleeding on enemies, causing them to slowly take damage over time.
1
Mystery Egg 5.100.539 Mystery Egg Sacrificial insemination Spawns an egg familiar, which hatches a random friendly monster when Isaac is hurt once per room. The power of the monster improves for each consecutive room cleared without taking damage.
0
Parasitoid 5.100.461 Parasitoid Egg tears! Adds a chance to fire an egg sack which creates slowing creep and spawns a Blue Fly or Blue Spider upon hitting an enemy.
3
Pointy Rib 5.100.544 Pointy Rib Stabbing time Spawns a bone familiar that hovers back and forth in front of Isaac, dealing damage equal to Isaac's damage.
1
Poke Go 5.100.505 Poke Go Gotta catch em... Upon entering a room with enemies in it, has a chance to spawn a random friendly enemy that persists across rooms.
2
Polydactyly 5.100.454 Polydactyly Hold me! Allows Isaac to carry two cards, pills, or any combination of both. Spawns one random card, rune, or pill.
2
Pop! 5.100.529 Pop! Eyeball tears! Replaces Isaac's tears with eyeballs that can bounce off of each other. The eyeballs are not limited by range, and will instead dissipate when they stop moving or when hitting an enemy or obstacle.
1
Sack of Sacks 5.100.500 Sack of Sacks Gives sacks Spawns a familiar that drops a Grab Bag.pngGrab Bag every few rooms cleared.
2
Schoolbag 5.100.534 Schoolbag Extra active item room Allows Isaac to hold two active items.
3
Shade 5.100.468 Shade It follows Spawns a shadow familiar that follows Isaac's movements on a 1 second delay and deals contact damage to enemies. After dealing enough damage, it is absorbed by Isaac and spawns friendly My Shadow.pngChargers.
0
Shard of Glass 5.100.448 Shard of Glass Blood and guts! (except in Repentance and Repentance+) Upon taking damage, Isaac has a chance to drop a full red heart, gain 5 range, and leave a trail of damaging red creep for the current room.
(in Repentance and Repentance+) Taking damage causes Isaac to bleed, spraying a volley of blood in the direction he fires. Bleeding will eventually damage him, but it can be stopped by picking up a Red Heart.pngRed Heart.
1
Sinus Infection 5.100.459 Sinus Infection Booger tears! Adds a chance to fire a booger that sticks to enemies and deals damage over time.
3
Slipped Rib 5.100.542 Slipped Rib Projectile shield Spawns a bone familiar that circles around Isaac and reflects enemy shots.
1
Sulfuric Acid 5.100.463 Sulfuric Acid Acid tears! +0.3 damage. Adds a chance to fire acidic tears which can destroy obstacles and open doors.
2
Tarot Cloth 5.100.451 Tarot Cloth I see the future Drops a random card or rune. (except in Repentance and Repentance+) Doubles the effects of most cards and runes. (in Repentance and Repentance+) Doubles the effects of tarot cards.
2
Technology Zero 5.100.524 Technology Zero Static tears! Connects Isaac's tears with electricity that can damage enemies.
3
Trisagion 5.100.533 Trisagion Smite thy enemy Tears are replaced with piercing white blasts of light that deal less damage but can damage the same enemy multiple times.
3
Varicose Veins 5.100.452 Varicose Veins I'm leaking... Taking damage releases a ring of 10 high damage tears.
0
YO LISTEN! 5.100.492 YO LISTEN! Yo listen! +1 luck. Spawns a fairy familiar that points out Secret RoomSecret Rooms, Crawl SpaceCrawl Space entrances, and tinted rocks.
2
Tonsil 5.100.474 Tonsil Gross... Grants a familiar that follows Isaac and blocks enemy shots.

Trinkets

38 new trinkets were added in the expansion.

Name ID Icon Quote Description
Baby-Bender 5.350.127 Baby-Bender Feed them magic! Grants Isaac's familiars homing shots.
Bag Lunch 5.350.105 Bag Lunch I wonder what it is Taking damage has a small chance to destroy the trinket and spawn Collectible Lunch icon.pngLunch.
Bat Wing 5.350.118 Bat Wing They are growing... Upon killing an enemy, has a 5% chance to grant flight for the rest of the room.
Black Tooth 5.350.95 Black Tooth It looks dead Adds a chance to fire a black tooth that deals double damage and poisons enemies.
Bloody Crown 5.350.111 Bloody Crown Drips with blood... Treasure RoomTreasure Rooms appear in Chapter 4.
Butter! 5.350.122 Butter! Can't hold it! Using an active item will drop it onto a pedestal on the ground. Taking damage may result in dropping an owned passive item.
Cracked Crown 5.350.92 Cracked Crown Stat booster (except in Repentance and Repentance+) Decreases Isaac's tear delay by 20%, and improves the effectiveness of his other stat upgrades by 33%.
(in Repentance and Repentance+) Improves the effectiveness of stat upgrades by 20%.
Crow Heart 5.350.107 Crow Heart Drain me Red Heart.pngRed Heart damage will be taken before Soul Heart.pngSoul Heart, Black Heart.pngBlack Heart, and (in Repentance and Repentance+) Rotten Heart.pngRotten Heart damage.
Dim Bulb 5.350.101 Dim Bulb I think it's broken Provides a boost to all stats when Isaac's active item is completely uncharged.
Door Stop 5.350.124 Door Stop Hold the door! The last door Isaac went through stays open, allowing him to leave the room even if enemies are in it.
Duct Tape 5.350.109 Duct Tape Stuck! Holds Isaac's familiars in place relative to his position.
Equality! 5.350.103 Equality! = Turns pickups into their doubled versions while Isaac's numbers of coins, bombs, and keys are equal.
Extension Cord 5.350.125 Extension Cord Charged friends Bolts of electricity arc between Isaac and his familiars, damaging any enemies between them.
Filigree Feather 5.350.123 Filigree Feather Angelic spoils Angels drop Angel Room items instead of key pieces when defeated.
Finger Bone 5.350.128 Finger Bone It looks brittle Grants a chance to gain a Bone Heart.pngBone Heart upon taking damage.
Fish Tail 5.350.94 Fish Tail It also stinks! Items and trinkets that generate Blue Flies or Locusts will generate twice as many.
Fragmented Card 5.350.102 Fragmented Card Double moon Makes two Secret RoomSecret Rooms spawn on each floor.
Hairpin 5.350.120 Hairpin Danger charge Fully recharges Isaac's active item upon entering a boss fight.
Locust of Conquest 5.350.117 Locust of Conquest I bring Conquest Upon entering a room with enemies, spawns 1-4 White Locusts which damage enemies.
Locust of Death 5.350.116 Locust of Death I bring Death Upon entering a room with enemies, spawns a Black Locust that does a very high amount of damage.
Locust of Famine 5.350.115 Locust of Famine I bring Famine Upon entering a room with enemies, spawns a Yellow Locust that damages and slows enemies.
Locust of Pestilence 5.350.114 Locust of Pestilence I bring Pestilence Upon entering a room with enemies, spawns a Green Locust which damages and poisons enemies.
Locust of War 5.350.113 Locust of War I bring War Upon entering a room with enemies for the first time, spawns a Red Locust which detonates upon impact with enemies.
Lost Cork 5.350.106 Lost Cork Uncorked Increases the radius of any creep produced by Isaac.
Meconium 5.350.91 Meconium Eww Black Poop.pngBlack Poops can drop Black Heart.pngBlack Hearts when destroyed. Poop.pngPoop has a chance to turn into Black Poop.pngBlack Poop.
Nose Goblin 5.350.98 Nose Goblin Seems magic... Chance to fire a homing booger that sticks to enemies and deals damage over time.
Ouroboros Worm 5.350.96 Ouroboros Worm Foop foop! Tears travel in a large spiral pattern and gain spectral, with a small chance to gain homing. (in Repentance and Repentance+) Also adds +0.4 Tears.
Pay to Win 5.350.112 Pay to Win ... Shop Restock Machine.pngShop Restock Machines always spawn in Treasure RoomTreasure Rooms.
Rotten Penny 5.350.126 Rotten Penny Wealth of flies Spawns a Blue Fly every time a coin is picked up.
Silver Dollar 5.350.110 Silver Dollar Feels lucky... ShopShops appear in Chapter 4.
Stem Cell 5.350.119 Stem Cell Regen! (except in Repentance and Repentance+) Heals Isaac for a Half Red Heart.pngHalf Red Heart upon traveling to the next floor.
(in Repentance and Repentance+) Heals 50% of Isaac's empty Red Heart.pngRed Heart containers upon traveling to the next floor.
Super Ball 5.350.99 Super Ball Boing! Makes tears have a chance to bounce off enemies and obstacles.
Tonsil 5.350.97 Tonsil Sick... When hit, there is a small chance to spawn a permanent tonsil familiar that blocks enemy shots. This can happen twice, after which the trinket is destroyed.
Used Diaper 5.350.93 Used Diaper You stink Grants the Collectible Skatole icon.pngSkatole effect in some rooms.
Vibrant Bulb 5.350.100 Vibrant Bulb It needs power Provides a boost to all stats when Isaac's active item is fully charged.
Walnut 5.350.108 Walnut That's a hard nut to crack! Being hit by explosions will eventually destroy the trinket and spawn various pickups.
Wish Bone 5.350.104 Wish Bone Make a wish Taking damage has a small chance to destroy the trinket and spawn a random item.
Wooden Cross 5.350.121 Wooden Cross My faith protects me Grants a shield that negates the first damage taken once per floor.

Pickups

Hearts

Heart ID Image Worth Additional Info Unlocked By
Scared Heart 9 Red Heart.png Full red heart Identical to the standard Red Heart, but will run away as the player moves towards it.
Heals Full red heartFull red heart with Collectible Maggy's Bow icon.pngMaggy's Bow.
Collectible Humbleing Bundle icon.pngHumbleing Bundle and Equality!Equality! will not double this.
Half Soul Heart 8 Half Soul Heart.png Half soul heart Mr. Resetter! Reset 7 times in a row

Switch PS4 Get a minus 10-win streak

Blended Heart 10 Blended Heart.png Full red heart/Full soul heart/Half red heartHalf soul heart Fills up a full red Heart Container, but will act as a Soul Heart when no Containers are free. If Isaac is only missing half a Red Heart, it will fill that half, and give him half a soul heart as well.
Collectible Dark Bum icon.pngDark Bum and Collectible The Jar icon.pngThe Jar will not collect this.
Bone Heart 11 Bone Heart.png Empty bone heart Takes three hits to deplete and can be refilled with red hearts, but disappears permanently upon depleting. Bone Heart It's complicated

Keys

Key ID Image Worth Additional Info Unlocked By
Charged Key 4 Charged Key.gif 1 Fully charges your currently held active item upon pickup.
Key Bum will pick this up, but will not give Isaac any active charge.
Charged Key Complete Pokey Mans (challenge #33)

Pills

ID Pill Effect
39 X-Lax

Creates a pool of slippery brown creep underneath Isaac.

40 Something's wrong...

Creates a pool of black creep beneath Isaac.

41 I'm Drowsy...

Upon use, slows all enemies for the duration of the room.

42 I'm Excited!!!

Upon use, increases the speed of all enemies for the duration of the room. The effect triggers again 30 seconds after use and 60 seconds after use.

43 Needs to be unlocked Gulp!

Upon use, any trinkets that the player is holding are destroyed, and their effects are permanently applied to the player.
Unlocked by acquiring the Once More With Feeling! achievement.

44 Needs to be unlocked Horf!

Upon use, Isaac shoots an explosive tear with the Collectible Ipecac icon.pngIpecac effect that always deals 200 damage.
Unlocked by acquiring the Dedication achievement.

45 Needs to be unlocked Feels like I'm walking on sunshine!

Temporarily makes Isaac invincible, similar to Collectible Unicorn Stump icon.pngUnicorn Stump.
Unlocked by acquiring the Sin Collector achievement.

46 Needs to be unlocked Vurp!

Throws up the last pill you used. Will spawn itself if no other pills were taken beforehand.
Unlocked by acquiring the U Broke It! achievement.

Cards

Name ID Icon Message Description
Ace of Clubs 5.300.27 Ace of Clubs Convert all Turns all Pickups, Chests, and (in Repentance and Repentance+) non-boss enemies in the room into random Bomb pickups, including Troll Bomb.pngTroll Bombs.
Ace of Diamonds 5.300.28 Ace of Diamonds Convert all Turns all Pickups, Chests, and (in Repentance and Repentance+) non-boss enemies in the room into random Coin pickups.
Ace of Spades 5.300.29 Ace of Spades Convert all Turns all Pickups, Chests, and (in Repentance and Repentance+) non-boss enemies in the room into random Key pickups.
Ace of Hearts 5.300.30 Ace of Hearts Convert all Turns all Pickups, Chests, and (in Repentance and Repentance+) non-boss enemies in the room into random Hearts.
Holy Card 5.300.51 Holy Card You feel protected (except in Repentance and Repentance+) Grants a shield that blocks the next hostile damage that would be taken in the current room. Has a chance to spawn another Holy Card on use.
(in Repentance and Repentance+) Grants a shield that blocks the next hostile damage that would be taken.
Huge Growth 5.300.52 Huge Growth Become immense! (except in Repentance and Repentance+) For the current room, makes Isaac larger, allows him to crush obstacles he walks on, and grants +7 flat Damage and +30 Range.
(in Repentance and Repentance+) For the current room, makes Isaac larger, allows him to crush obstacles he walks on, and grants +7 flat Damage and +3 Range.
Ancient Recall 5.300.53 Ancient Recall Draw 3 cards Spawns 3 random cards.
Era Walk 5.300.54 Era Walk Savor the moment For the current room, enemies are slowed, Isaac's speed is increased by 0.50, and his shot speed is decreased by 1.00.

Runes

Name ID Icon Message Description
Black Rune 5.300.41 Black Rune Void Deals 40 damage to all enemies in the room. Consumes all pickups in the room and turns them into Blue Flies and Spiders. Consumes all pedestal items in the room and turns them into random stat upgrades.

Chests

Mimic Chest.png Mimic Chests
  • Mimic Chests appear similar to Brown Chests until Isaac moves near, at which point they sprout spikes that damage the player as a Spike Chest would. They can be distinguished from Brown Chests by their darker, purplish-brown coloring, the grayish spot on each side of the latch where the spikes will sprout from and the bloodstain.

Entities

Monsters

Entity ID Description
Blended Heart
Blended Heart
5.10.10 {{{behavior}}}
Bone Heart
Bone Heart
5.10.11 {{{behavior}}}
Half Soul Heart
Half Soul Heart
5.10.8 {{{behavior}}}
Scared Heart
Scared Heart
5.10.9 {{{behavior}}}
Charged Key
Charged Key
5.30.4 {{{behavior}}}
Mimic Chest
Mimic Chest
5.54 {{{behavior}}}
Dank Charger
Dank Charger
23.2 Slowly moves around the room, launching itself at Isaac if he gets in its line of sight. Bounces off of walls and leaves a trail of slowing Black Creep while charging.
Mr. Red Maw
Mr. Red Maw
35.2 Walks towards Isaac and attacks by launching its head towards him. Turns into a Red Maw.pngRed Maw or Gusher upon death depending on the killed body segment. Occasionally separates at will.
Soul Sucker
Soul Sucker
61.2 Flies slowly towards Isaac. Spawns a vortex that fires four Collectible Brimstone icon.pngBrimstone beams in the cardinal directions upon death.
Cross Stone Shooter
Cross Stone Shooter
202.10 Stationary and invulnerable monster that continuously fires shots in four directions, alternating between cardinal and ordinal.
Crispy
Crispy
226.2 Slowly walks towards Isaac, but increases in speed as they take damage. Constantly passively takes damage.
Nerve Ending 2
Nerve Ending 2
231.1 Static enemy which whips at Isaac if he gets too close.
Tube Worm
Tube Worm
244.1 Pops out of the ground in random locations and fires a long-range spray of arcing shots where Isaac will be.
White Poop
White Poop
245.4 {{{behavior}}}
Mushroom
Mushroom
300.0 Stationary enemy that occasionally pops up and fires four shots in the cardinal or diagonal directions. Takes less damage while its head is down.
Poison Mind
Poison Mind
301.0 Slowly (except in Repentance and Repentance+)crawls/(in Repentance and Repentance+)floats around the room diagonally, leaving a trail of damaging green creep. (in Repentance and Repentance+) Explodes upon death.
Stoney
Stoney
302.0 Chases Isaac and blocks tears, but does not deal contact damage. Temporarily pauses in exhaustion after a certain amount of time. Invulnerable; dies when the room is cleared.
Cross Stoney
Cross Stoney
302.10 Chases Isaac and shoots 4 tears vertically and diagonally like a Cross Grimace.pngCross Stone Shooter. Dies when the room is cleared.
Only appears in Aprils Fool (challenge #32) as replacements to regular Stoneys.
Blister
Blister
303.0 Slowly hops towards Isaac, occasionally spawning a Dark Ball. Spawns a Sack.pngSack upon death.
The Thing
The Thing
304.0 Crawls along a wall and attempts to line up with Isaac, then spits a line of damaging Red Creep.
Ministro
Ministro
305.0 Hops around randomly and hop towards Isaac when he gets close, occasionally spitting out a cluster of disorganized shots.
Portal
Portal
306.0 Spawns various enemies from the current floor until it either vanishes or is killed.
Tar Boy
Tar Boy
307.0 Fires a short-ranged spray of shots that leave behind slowing Black Creep. Occasionally burrows underground and reappears under any pools of black creep in the room. If Isaac stands on the Creep, the Tar Boy can (except in Repentance and Repentance+) fire shots straight upwards out of the Creep underneath Isaac/(in Repentance and Repentance+) send out a tentacle underneath Isaac.
Fistuloid
Fistuloid
308.0 Flies towards Isaac in an erratic waving motion, periodically firing a blood shot towards Isaac that also knocks itself back. Upon death, fires a worm that flies off screen.
Gush
Gush
309.0 Stationary, harmless enemy that continually creates slowing black creep.
Leper
Leper
310.0 Alternating between walking towards and running away from Isaac. Releases a Leper Flesh each time it takes enough damage. At low health, constantly chases Isaac and leaves behind damaging red creep. Spawns a Leper Flesh and Gusher.pngGusher upon death.
Leper Flesh
Leper Flesh
310.1 Floats slowly toward Isaac and fires a predictive projectile at him upon death.
Mr. Mine
Mr. Mine
311.0 Can only appear in pits. Attempts to launch itself at Isaac if he comes near. Occasionally burrows and pops up in another pit, and fires six shots in all directions upon death.
Purple Ball
Purple Ball
409.1 Floats towards Isaac, doing contact damage.

Bosses

5 bosses were added in Afterbirth †. Additionally, Ultra Greed received a second form in Greed Mode's hard mode.

Boss Rag Mega portrait.png
Boss Big Horn portrait.png
Boss Sisters Vis portrait.png
Boss The Matriarch portrait.png
Rag Mega Big Horn Sisters Vis The Matriarch
Boss Delirium portrait.png
Boss Ultra Greedier ingame.png
Delirium Ultra Greedier

Environment

Chapters

The Void
The VoidThe Void

Obstacles

Super Special Rocks.png Super special rock
  • Super special rocks are tinted rock variants which are much harder to spot, as they have a smaller mark and are not discolored. Super special rocks takes two bombs to blow up, and drop the contents of two tinted rocks.
White Poop.png White poop
  • White poop is surrounded by an aura that halves tear delay and has a high chance to block damage like the Collectible Cone Head Afterbirth+ icon.pngCone Head item while Isaac stands within it. The aura disappears if the poop is destroyed.
Dirt Patch.pngDirt Patch Forgotten.png Dirt Patch

Machines

Mom's Dressing Table.png Mom's Dressing Table

Challenges

Name Conditions Goal Unlocked by Unlocks
31. Backasswards
Character Isaac appearance.png
Full red heartFull red heartFull red heart
Starts with:
8-10 random items
Item Pool Treasure Room.png: no
Item Pool Shop.png: yes
All chapters progress in reverse order, losing 1 item and 1 Red Heart container each floor ascended.
BasementBasement/CellarCellar/Burning BasementBurning Basement I Backasswards (except in Repentance and Repentance+) Defeat ??? or The Lamb
(in Repentance and Repentance+) Defeat Mega Satan and unlock Collectible The Negative icon.pngThe Negative
Laz Bleeds More! Laz Bleeds More!
32. Aprils Fool
Character Isaac appearance.png
Full red heartFull red heartFull red heart
Item Pool Treasure Room.png: yes
Item Pool Shop.png: yes
The minimap displays the floor's layout accurately but displays Isaac's position inaccurately. Pedestal items and pickups are not what they appear to be. Active items, pills, cards, and rune effects are randomized upon each use, making them very unreliable or deadly (for example Suicide KingSuicide King). Items with no charge time (i.e. Collectible How to Jump icon.pngHow to Jump, Collectible IV Bag icon.pngIV Bag, etc) can be used repeatedly for random effects. Stoney.pngStonies have a chance of being replaced by a Cross Stoney.pngCross Stoney. Every boss is Boss The Bloat ingame.pngThe Bloat. Isaac's health is not what it appears to be. Inventory pickups numbers are accurate.
Boss Mom's Heart portrait.png Aprils fool Defeat Mom Maggy Now Holds a Pill! Maggy Now Holds a Pill!
33. Pokey Mans
Character Isaac appearance.png
Full red heartFull red heartFull red heart
Starts with:
Collectible Friendly Ball icon.pngFriendly Ball
Collectible Mom's Eyeshadow icon.pngMom's Eyeshadow
Item Pool Treasure Room.png: no
Item Pool Shop.png: yes
Each use of Friendly Ball causes a random monster to be spawned. Friendly Ball instantly charges once the spawned monster is killed.
Boss Isaac portrait.png Pokey Mans Defeat Mom's Heart 11 times Charged Key Charged Key
34. Ultra Hard
Character Isaac appearance.png
Full red heartFull red heartFull red heart
Starts with:
Collectible Key Piece 1 icon.pngKey Piece 1
Collectible Key Piece 2 icon.pngKey Piece 2
Curse of the Labyrinth.pngCurse of the Labyrinth
Curse of the Blind.pngCurse of the Blind
Curse of the Lost.pngCurse of the Lost
Curse of the Maze.pngCurse of the Maze
Item Pool Treasure Room.png: yes
Item Pool Shop.png: yes
All enemies spawn as champions if possible. Boss fights will be double trouble if possible. No heart pickups drop.
Boss Mega Satan portrait.png Ultra Hard (except in Repentance and Repentance+) Defeat ??? or The Lamb. Possession of Collectible The Polaroid icon.pngThe Polaroid / Collectible The Negative icon.pngThe Negative is required, barring getting to Dark RoomDark Room through a Sacrifice RoomSacrifice Room.
(in Repentance and Repentance+) Defeat Mega Satan and unlock Collectible The Negative icon.pngThe Negative
Samson Feels Healthy! Samson Feels Healthy!
35. Pong
Character Isaac appearance.png
Full red heartFull red heartFull red heart
Starts with:
Collectible Cupid's Arrow icon.pngCupid's Arrow
Collectible Rubber Cement icon.pngRubber Cement
Item Pool Treasure Room.png: no
Item Pool Shop.png: yes
Damage fixed at 100, tear delay fixed at 150.
Boss ??? portrait.png PONG Defeat Isaac 5 times Greed's Gullet Greed's Gullet

Achievements

Name Image Description Unlock In Game Secret Number


1000000% 1000000% Just Stop! Collect every item in the game, unlock all secrets and endings, and complete the Bestiary 339
5 Nights at Mom's 5 Nights at Mom's Unlocked super special rocks. Get a 5-win streak, using a different character each time ((in Repentance and Repentance+) this number can be reduced to 3, see the notes section) 323
7 Seals 7 Seals Unlocked a new item. Defeat all 5 Harbingers 372
Ancient Recall Ancient Recall Unlocked a new item. Use Cards and Runes 20 times 362
Angelic Prism Angelic Prism Unlocked a new item. Defeat an Angel 10 times 373
Angry Fly Angry Fly Unlocked a new item. Become Beelzebub 352
Apollyon Apollyon Unlocked a new character. Defeat Mega Satan 340
Apollyon Baby Apollyon Baby Unlocked a new co-player baby. Earn all Hard mode Completion Marks as Character Apollyon icon.pngApollyon 319
Aprils fool Aprils fool Unlocked a new challenge. Defeat Mom 278
Baby-Bender Baby-Bender Unlocked a new item. Use I - The MagicianI - The Magician or Collectible Telepathy For Dummies icon.pngTelepathy For Dummies while already having homing tears 389
Backasswards Backasswards Unlocked a new challenge. (except in Repentance and Repentance+) Defeat ??? or The Lamb
(in Repentance and Repentance+) Defeat Mega Satan and unlock Collectible The Negative icon.pngThe Negative
277
Bat Wing Bat Wing Unlocked a new item. Defeat Ultra Greedier as Character Azazel icon.pngAzazel 304
Black Hole Black Hole Unlocked a new item. Defeat 20 Portals 349
Black Rune Black Rune Unlocked a new item. Defeat Ultra Greedier as Character Apollyon icon.pngApollyon 309
Blanket Blanket Unlocked a new item. Sleep in 10 beds 385
Bloody Crown Bloody Crown Unlocked a new item. Defeat Delirium as Character Samson icon.pngSamson 287
Bone Baby Bone Baby Unlocked a new co-player baby. Earn all Hard mode Completion Marks as Character The Forgotten icon.pngThe Forgotten 402
Bone Heart Bone Heart Unlocked a new item. It's complicated 391
Book of the Dead Book of the Dead Unlocked a new item. Defeat Delirium as Character The Forgotten icon.pngThe Forgotten 401
Bound Baby Bound Baby Unlocked a new co-player baby. Defeat Mega Satan as Character The Forgotten icon.pngThe Forgotten 403
Bozo Bozo Unlocked a new item. Destroy 5 rainbow poops 353
Brittle Bones Brittle Bones Unlocked a new item. Defeat The Lamb as Character The Forgotten icon.pngThe Forgotten 396
Broken Modem Broken Modem Unlocked a new item. Complete 7 Daily Challenges (by touching the trophy at the end) 354
Brown Nugget Brown Nugget Unlocked a new item. Defeat Ultra Greed as Character Apollyon icon.pngApollyon 316
Buddy in a Box Buddy in a Box Unlocked a new item. Pick up 5 familiars in a single run 355
Burning Basement Burning Basement Alt stage to the basement. Defeat Mom's Heart 11 times 342
Butter! Butter! Unlocked a new item. Complete 2 Victory Laps by defeating The Lamb 360
Charged Key Charged Key Unlocked a new item. Complete Pokey Mans (challenge #33) 333
Compound Fracture Compound Fracture Unlocked a new item. Defeat Delirium as Character Lazarus icon.pngLazarus 291
Coupon Coupon Unlocked a new item. Purchase anything from ShopShops, Devil RoomDevil Rooms, and/or Black MarketBlack Markets 50 times 364
Crooked Penny Crooked Penny Unlocked a new item. Defeat Delirium as Character Keeper icon.pngKeeper 294
Crow Heart Crow Heart Unlocked a new item. Defeat Ultra Greedier as Character Eve icon.pngEve 302
D infinity D infinity Unlocked a new item. Defeat Delirium as Character Isaac icon.pngIsaac 282
D1 D1 Unlocked a new item. Defeat Ultra Greedier as Character Isaac icon.pngIsaac 296
Dad's Lost Coin Dad's Lost Coin Unlocked a new item. Defeat Ultra Greedier as Character The Lost icon.pngThe Lost 307
Dad's Ring Dad's Ring Unlocked a new item. Defeat Ultra Greedier as Character The Forgotten icon.pngThe Forgotten 400
Dank Depths Dank Depths Alt stage to the depths. Defeat It Lives! 21 times 344
Dark Prince's Crown Dark Prince's Crown Unlocked a new item. Defeat Delirium as Character Azazel icon.pngAzazel 290
Death's List Death's List Unlocked a new item. Take 25 Deals with the Devil 376
Dedication Dedication Unlocked a new item. Participate in 31 Daily Challenges (they don't have to be consecutive; it will still count if Isaac dies in the first room) 325
Delirious Delirious Unlocked a new item. Defeat Delirium 338
Divorce Papers Divorce Papers Unlocked a new item. Complete the Boss RushBoss Rush as Character The Forgotten icon.pngThe Forgotten 397
Door Stop Door Stop Unlocked a new item. Blow up doors and Secret RoomSecret Room walls 50 times 375
Duality Duality Unlocked a new item. Defeat Ultra Greedier as Character Lilith icon.pngLilith 306
Dull Razor Dull Razor Unlocked a new item. Defeat Delirium as Character Eve icon.pngEve 288
Eden's Soul Eden's Soul Unlocked a new item. Defeat Delirium as Character Eden icon.pngEden 289
Era Walk Era Walk Unlocked a new item. Add both the Collectible Broken Watch icon.pngBroken Watch and the Collectible Stop Watch icon.pngStop Watch to your collection 363
Eucharist Eucharist Unlocked a new item. Defeat Delirium as Character Magdalene icon.pngMagdalene 283
Euthanasia Euthanasia Unlocked a new item. Defeat Delirium as Character Lilith icon.pngLilith 292
Extension Cord Extension Cord Unlocked a new item. Have Collectible The Battery icon.pngThe Battery, Collectible 9 Volt icon.png9 Volt, and Collectible Car Battery icon.pngCar Battery in Isaac's collection 381
Eye of Belial Eye of Belial Unlocked a new item. Defeat Ultra Greedier as Character Judas icon.pngJudas 299
Eye of Greed Eye of Greed Unlocked a new item. Defeat Ultra Greedier as Character Keeper icon.pngKeeper 308
Fast Bombs Fast Bombs Unlocked a new item. Defeat Little Horn 20 times 356
Filigree Feather Filigree Feather Unlocked a new item. Acquire both Collectible Key Piece 1 icon.pngKey Piece 1 and Collectible Key Piece 2 icon.pngKey Piece 2 370
Finger Bone Finger Bone Unlocked a new item. Defeat Ultra Greed as Character The Forgotten icon.pngThe Forgotten 399
Flat Stone Flat Stone Unlocked a new item. Acquire Collectible Rubber Cement icon.pngRubber Cement 5 times 382
Flooded Caves Flooded Caves Alt stage to the caves. Defeat It Lives! 16 times 343
Glyph of Balance Glyph of Balance Unlocked a new item. Defeat Ultra Greedier as Character Magdalene icon.pngMagdalene 297
Greed's Gullet Greed's Gullet Unlocked a new item. Complete Pong (challenge #35) 335
Greedier! Greedier! New mode unlocked! Donate 500 Coins to the Greed Donation Machine.pngGreed Donation Machine 341
Haemolacria Haemolacria Unlocked a new item. Acquire Collectible Blood Clot icon.pngBlood Clot 10 times 377
Hairpin Hairpin Unlocked a new item. Recharge using Lil' Batteries 20 times 358
Hallowed Ground Hallowed Ground Unlocked a new item. Defeat Hush as Character The Forgotten icon.pngThe Forgotten 398
Hat trick! Hat trick! Unlocked a new item. Get a 3-win streak 322
Holy Card Holy Card Unlocked a new item. Defeat Delirium as Character The Lost icon.pngThe Lost 293
Huge Growth Huge Growth Unlocked a new item. Increase in size 5 times in a single run via Collectible Magic Mushroom icon.pngMagic Mushroom, "One makes you larger" pills, XI - StrengthXI - Strength, etc. 361
Hushy Hushy Unlocked a new item. Defeat Hush as Character Apollyon icon.pngApollyon 315
It's the Key It's the Key Unlocked a new item. Defeat Boss The Lamb ingame.pngThe Lamb without taking Hearts, Coins, or Bombs through the entire run. Letting certain familiars (e.g. Collectible Bum Friend icon.pngBum Friend, Collectible Dark Bum icon.pngDark Bum, (except in Rebirth)Collectible Bumbo icon.pngBumbo or (in Repentance and Repentance+)Collectible Lil Portal icon.pngLil Portal) or bosses (e.g. (in Repentance and Repentance+) Boss Bumbino ingame.pngBumbino) pick up the consumables fails this condition as well. 327
Jaw Bone Jaw Bone Unlocked a new item. Defeat ??? as Character The Forgotten icon.pngThe Forgotten 395
Jumper Cables Jumper Cables Unlocked a new item. Pick up any 2 of the following items/trinkets in a single run: Collectible 9 Volt icon.png9 Volt, Collectible The Battery icon.pngThe Battery, Collectible Car Battery icon.pngCar Battery, AAA BatteryAAA Battery, and Watch BatteryWatch Battery ((in Repentance and Repentance+) Any 2 items that have the 'battery' item tag) 367
King Baby King Baby Unlocked a new co-player baby. Defeat Delirium as Character ??? (Character) icon.png??? 286
Lachryphagy Lachryphagy Unlocked a new item. Collect 10 "Tears Up" items or pills in one run 378
Laz Bleeds More! Laz Bleeds More! Unlocked a new starting item. Complete Backasswards (challenge #31) 331
Leprosy Leprosy Unlocked a new item. Beat Chapter 3 without taking damage 368
Lil Delirium Lil Delirium Unlocked a new item. Defeat Delirium for the 1st time 357
Lil Spewer Lil Spewer Unlocked a new item. Have Isaac die to his own explosion from Collectible Ipecac icon.pngIpecac, Collectible Bob's Rotten Head icon.pngBob's Rotten Head, or a Horf! pill 384
Living on the edge Living on the edge Unlocked a new item. Complete a Chapter (floors I and II) after BasementBasement, start-to-finish, with only half a Heart total (can use Character The Lost icon.pngThe Lost) 329
Locust of Conquest Locust of Conquest Unlocked a new item. Complete the Boss RushBoss Rush as Character Apollyon icon.pngApollyon 314
Locust of Death Locust of Death Unlocked a new item. Defeat The Lamb as Character Apollyon icon.pngApollyon 313
Locust of Famine Locust of Famine Unlocked a new item. Defeat ??? as Character Apollyon icon.pngApollyon 312
Locust of Pestilence Locust of Pestilence Unlocked a new item. Defeat Satan as Character Apollyon icon.pngApollyon 311
Locust of Wrath Locust of Wrath Unlocked a new item. Defeat Isaac as Character Apollyon icon.pngApollyon 310
Maggy Now Holds a Pill! Maggy Now Holds a Pill! Unlocked a new starting item. Complete Aprils Fool (challenge #32) 332
Marbles Marbles Unlocked a new item. Use 5 Gulp! pills in one run (Collectible Placebo icon.pngPlacebo uses count) 386
Marrow Marrow Unlocked a new item. Defeat Mom's Heart or It Lives! on Hard mode as Character The Forgotten icon.pngThe Forgotten 392
Meconium Meconium Unlocked a new item. Defeat Ultra Greedier as Character ??? (Character) icon.png??? 300
Metronome Metronome Unlocked a new item. Defeat Ultra Greedier as Character Eden icon.pngEden 303
Mort Baby Mort Baby Unlocked a new co-player baby. Defeat Mega Satan as Character Apollyon icon.pngApollyon 317
Moving Box Moving Box Unlocked a new item. Use Collectible Pandora's Box icon.pngPandora's Box in Dark RoomDark Room 366
Mr. ME! Mr. ME! Unlocked a new item. Open 20 Locked Chests 371
Mr. Resetter! Mr. Resetter! Unlocked a new item. Reset 7 times in a row

Switch PS4 Get a minus 10-win streak

328
Mystery Egg Mystery Egg Unlocked a new item. Spawn three charmed enemies in the same room 387
Mystery Gift Mystery Gift Unlocked a new item. Destroy 500 rocks 350
New Area New Area Unlocked a new area. Defeat Hush 320
Once More with Feeling! Once More with Feeling! Unlocked a new item. Complete a Victory Lap by defeating The Lamb 321
Plan C Plan C Unlocked a new item. Defeat Ultra Greedier as Character Lazarus icon.pngLazarus 305
Pointy Rib Pointy Rib Unlocked a new item. Defeat Satan as Character The Forgotten icon.pngThe Forgotten 394
Pokey Mans Pokey Mans Unlocked a new challenge. Defeat Mom's Heart 11 times 279
PONG PONG Unlocked a new challenge. Defeat Isaac 5 times 281
Pop! Pop! Unlocked a new item. Beat Chapter 4 without taking damage 374
RERUN RERUN Unlocked the power of RERUN. Complete 3 Victory Laps by defeating The Lamb 337
Rotten Penny Rotten Penny Unlocked a new item. Have 20 Blue Flies at the same time 388
Sack of Sacks Sack of Sacks Unlocked a new item. Defeat Ultra Greedier as Character Cain icon.pngCain 298
Sacrificial Altar Sacrificial Altar Unlocked a new item. Take 50 Deals with the Devil 383
Samson Feels Healthy! Samson Feels Healthy! Unlocked a new starting item. Complete Ultra Hard (challenge #34) 334
Scarred Womb Scarred Womb Alt stage to the womb. Defeat It Lives! 30 times 345
Schoolbag Schoolbag Unlocked a new item. Enter 6 ShopShops in one run 379
Shade Shade Unlocked a new item. Defeat Delirium as Character Judas icon.pngJudas 285
Silver Dollar Silver Dollar Unlocked a new item. Defeat Delirium as Character Cain icon.pngCain 284
Sin collector Sin collector Unlocked a new item. Collect every entry in the Bestiary (bugged v190 - Mobs that don't exist in the bestiary are being counted. This allows Sin Collector to be unlocked without a complete bestiary) 324
Slipped Rib Slipped Rib Unlocked a new item. Defeat Isaac as Character The Forgotten icon.pngThe Forgotten 393
Smelter Smelter Unlocked a new item. Defeat Mom's Heart or It Lives! on Hard mode as Character Apollyon icon.pngApollyon 318
Something wicked this way comes! Something wicked this way comes! Unlocked new bosses! Defeat ??? as 3 different Characters 346
Something wicked this way comes+! Something wicked this way comes+! Unlocked even more bosses! Defeat ??? as 6 different Characters 347
Sprinkler Sprinkler Unlocked a new item. Beat Chapter 1 without taking damage 351
Stem Cell Stem Cell Unlocked a new item. Defeat Ultra Greedier as Character Samson icon.pngSamson 301
Technology Zero Technology Zero Unlocked a new item. Pick up any 2 technology items in a single run ((in Repentance and Repentance+) Any 2 items that have the 'tech' item tag) 369
Telekinesis Telekinesis Unlocked a new item. Beat Chapter 2 without taking damage 365
The Forgotten The Forgotten Unlocked a new character. It's complicated 390
The gate is open! The gate is open! Unlocked new enemies! Defeat The Lamb 348
The Marathon The Marathon Unlocked a new item. Get a 5-win streak in the Daily Challenges (they don't have to be consecutive days, only the runs you play are counted) 336
Trisagion Trisagion Unlocked a new item. Take 25 Angel Rooms items 380
U Broke It! U Broke It! Unlocked a new item. Obtain 50 items in a run (duplicate passive items/familiars count towards the total, e.g., multiple Collectible Breakfast icon.pngBreakfast) 330
Ultra Hard Ultra Hard Unlocked a new challenge. (except in Repentance and Repentance+) Defeat ??? or The Lamb. Possession of Collectible The Polaroid icon.pngThe Polaroid / Collectible The Negative icon.pngThe Negative is required, barring getting to Dark RoomDark Room through a Sacrifice RoomSacrifice Room.
(in Repentance and Repentance+) Defeat Mega Satan and unlock Collectible The Negative icon.pngThe Negative
280
Void Void Unlocked a new item. Defeat Delirium as Character Apollyon icon.pngApollyon 295
Wooden Cross Wooden Cross Unlocked a new item. Sleep in a bed 359
ZIP! ZIP! Unlocked a new item. Defeat The Lamb in under 20 minutes 326

Changes

Menus

Collection page
  • The navigation is faster and loops back on itself when scrolling vertically.
Loading screen
  • Loading images are smoother.

Player

Characters

General
  • Adjusted the stats of each character in the character selection menu to better reflect their actual in-game stats.
  • Adjusted pickup animation so items no longer obstruct Isaac's face.
  • Bloodstains on costumes are now consistently the same color.
Eden
  • Holding R to reset will consume an Eden Token and start a new run.
  • Added 30 hairstyles.
  • Can be randomized if the player has Eden tokens.
Eve
  • Starts with Razor Blade only if it has been unlocked.
  • Leaves a pool of blood behind instead of pee when walking between rooms at low HP.
Lilith

Transformations

Conjoined
  • Its costume has color alts.
Seraphim
  • Its costume has color alts.
Spun
  • Its costume has color alts.
Yes Mother?
  • Its costume has color alts.

Familiars

  • Teleport to the player's new position if it was changed by a boss such as Gurdy or Mom's Heart.
  • Most sources of Blue Spiders throw those spiders out instead of spawning them on the ground.
  • Following familiars are no longer pushed back when very close to the player.

Co-op

  • Co-op babies can no longer drop out while the player is playing a pickup animation.

Items

General
  • Mushroom items play their unique pickup sound.

Activated Collectibles

General
  • Some sprites changed:
Item Old sprite New sprite
The Boomerang Collectible The Boomerang Rebirth icon.png Collectible The Boomerang icon.png
Box of Spiders Collectible Box of Spiders Rebirth icon.png Collectible Box of Spiders icon.png
D20 Collectible D20 Rebirth icon.png Collectible D20 icon.png
D7 Collectible D7 Afterbirth icon.png Collectible D7 icon.png
Glass Cannon Collectible Glass Cannon Afterbirth icon.png Collectible Glass Cannon icon.png
Isaac's Tears Collectible Isaac's Tears Rebirth icon.png Collectible Isaac's Tears icon.png
The Jar Collectible The Jar Afterbirth icon.png Collectible The Jar icon.png
Jar of Flies Collectible Jar of Flies Afterbirth icon.png Collectible Jar of Flies icon.png
Mega Blast Collectible Mega Blast Afterbirth icon.png Collectible Mega Blast icon.png
Ventricle Razor Collectible Ventricle Razor Afterbirth icon.png Collectible Ventricle Razor icon.png
We Need To Go Deeper! Collectible We Need To Go Deeper! Rebirth icon.png Collectible We Need To Go Deeper! icon.png
Collectible Breath of Life Rebirth icon.pngBreath of Life
  • Can be held down between rooms.
  • Added some visual feedback when it provides its invincibility.
Collectible Butter Bean icon.pngButter Bean
  • If Isaac swaps Butter Bean for a different active item, then picks up Butter Bean again, it has a small chance to transform into Wait What?.
Collectible D4 icon.pngD4
  • Re-rolls each of Isaac's passive items into a random item from the specific item pool where it was acquired.
Collectible Diplopia icon.pngDiplopia
  • No longer spawns extra items for empty item pedestals.
Collectible Flush! icon.pngFlush!
  • Poops spawned react to damage similarly to regular poops.
Collectible Friendly Ball icon.pngFriendly Ball
Collectible Glowing Hourglass icon.pngGlowing Hourglass
Collectible Guppy's Head icon.pngGuppy's Head
  • The number of flies is seeded.
Collectible Head of Krampus icon.pngHead of Krampus
  • Lasers no longer have a chance to rotate.
Collectible The Jar icon.pngThe Jar
  • Its sprite changes based on how many hearts it contains.
Collectible Jar of Flies icon.pngJar of Flies
  • Its sprite changes based on how many flies it contains.
Collectible Mine Crafter Afterbirth icon.pngMine Crafter
  • Spawns a TNT barrel directly at the player's position rather than on a nearby free tile.
Collectible My Little Unicorn icon.pngMy Little Unicorn
  • Its costume has color alts.
Collectible Pandora's Box icon.pngPandora's Box
Collectible Satanic Bible icon.pngSatanic Bible
  • Plays its use animation.
Collectible Shoop da Whoop! icon.pngShoop da Whoop!
  • Damage halved to compensate.
Collectible Undefined icon.pngUndefined
  • The Void is reset on exiting the I AM ERROR room and can be cleared repeatedly as long as the player is able to gather enough charges to successfully warp to it.
Collectible Ventricle Razor Afterbirth+ icon.pngVentricle Razor
  • Portals will now appear closed if they have no connected portal.
  • Portals got a few minor visual tweaks.

Passive Collectibles

General
  • Some sprites changed:
Item Old sprite New sprite
<3 Collectible Less Than Three Rebirth icon.png Collectible Less Than Three icon.png
8 Inch Nails Collectible 8 Inch Nails Afterbirth icon.png Collectible 8 Inch Nails icon.png
Abaddon Collectible Abaddon Rebirth icon.png Collectible Abaddon icon.png
Anemic Collectible Anemic Rebirth icon.png Collectible Anemic icon.png
Aquarius Collectible Aquarius Rebirth icon.png Collectible Aquarius icon.png
The Belt Collectible The Belt Rebirth icon.png Collectible The Belt icon.png
Best Bud Collectible Best Bud Rebirth icon.png Collectible Best Bud icon.png
Black Lotus Collectible Black Lotus Rebirth icon.png Collectible Black Lotus icon.png
Bob's Curse Collectible Bob's Curse Rebirth icon.png Collectible Bob's Curse icon.png
Box Collectible Box Rebirth icon.png Collectible Box icon.png
Brimstone Collectible Brimstone Rebirth icon.png Collectible Brimstone icon.png
Brother Bobby Collectible Brother Bobby Rebirth icon.png Collectible Brother Bobby icon.png
Bum Friend Collectible Bum Friend Rebirth icon.png Collectible Bum Friend icon.png
Caffeine Pill Collectible Caffeine Pill Rebirth icon.png Collectible Caffeine Pill icon.png
Cambion Conception Collectible Cambion Conception Afterbirth icon.png Collectible Cambion Conception icon.png
Cancer Collectible Cancer Rebirth icon.png Collectible Cancer icon.png
Celtic Cross Collectible Celtic Cross Rebirth icon.png Collectible Celtic Cross icon.png
The Compass Collectible The Compass Rebirth icon.png Collectible The Compass icon.png
Continuum Collectible Continuum Afterbirth icon.png Collectible Continuum icon.png
Cricket's Head Collectible Cricket's Head Rebirth icon.png Collectible Cricket's Head icon.png
Crown Of Light Collectible Crown Of Light Afterbirth icon.png Collectible Crown Of Light icon.png
Cupid's Arrow Collectible Cupid's Arrow Rebirth icon.png Collectible Cupid's Arrow icon.png
Daddy Longlegs Collectible Daddy Longlegs Rebirth icon.png Collectible Daddy Longlegs icon.png
Dark Bum Collectible Dark Bum Rebirth icon.png Collectible Dark Bum icon.png
Demon Baby Collectible Demon Baby Rebirth icon.png Collectible Demon Baby icon.png
Distant Admiration Collectible Distant Admiration Rebirth icon.png Collectible Distant Admiration icon.png
Evil Eye Collectible Evil Eye Afterbirth icon.png Collectible Evil Eye icon.png
Farting Baby Collectible Farting Baby Afterbirth icon.png Collectible Farting Baby icon.png
Forever alone Collectible Forever alone Rebirth icon.png Collectible Forever alone icon.png
Friend Zone Collectible Friend Zone Afterbirth icon.png Collectible Friend Zone icon.png
Gemini Collectible Gemini Rebirth icon.png Collectible Gemini icon.png
Ghost Baby Collectible Ghost Baby Rebirth icon.png Collectible Ghost Baby icon.png
Goat Head Collectible Goat Head Rebirth icon.png Collectible Goat Head icon.png
Guppy's Hairball Collectible Guppy's Hairball Rebirth icon.png Collectible Guppy's Hairball icon.png
Habit Collectible Habit Rebirth icon.png Collectible Habit icon.png
Harlequin Baby Collectible Harlequin Baby Rebirth icon.png Collectible Harlequin Baby icon.png
Holy Water Collectible Holy Water Rebirth icon.png Collectible Holy Water icon.png
Infestation Collectible Infestation Rebirth icon.png Collectible Infestation icon.png
Key Bum Collectible Key Bum Afterbirth icon.png Collectible Key Bum icon.png
Key Piece 2 Collectible Key Piece 2 Rebirth icon.png Collectible Key Piece 2 icon.png
Lil Brimstone Collectible Lil Brimstone Rebirth icon.png Collectible Lil Brimstone icon.png
Lil' Loki Collectible Lil Loki Afterbirth icon.png Collectible Lil Loki icon.png
Lord of the Pit Collectible Lord of the Pit Rebirth icon.png Collectible Lord of the Pit icon.png
Lost Fly Collectible Lost Fly Afterbirth icon.png Collectible Lost Fly icon.png
Lucky Foot Collectible Lucky Foot Rebirth icon.png Collectible Lucky Foot icon.png
Magic 8 Ball Collectible Magic 8 Ball Rebirth icon.png Collectible Magic 8 Ball icon.png
Magneto Collectible Magneto Rebirth icon.png Collectible Magneto icon.png
Mitre Collectible Mitre Rebirth icon.png Collectible Mitre icon.png
Mom's Contacts Collectible Mom's Contacts Rebirth icon.png Collectible Mom's Contacts icon.png
Mom's Eye Collectible Mom's Eye Rebirth icon.png Collectible Mom's Eye icon.png
Mom's Knife Collectible Mom's Knife Rebirth icon.png Collectible Mom's Knife icon.png
Money = Power Collectible Money = Power Rebirth icon.png Collectible Money = Power icon.png
The Mulligan Collectible The Mulligan Rebirth icon.png Collectible The Mulligan icon.png
Multidimensional Baby Collectible Multidimensional Baby Afterbirth icon.png Collectible Multidimensional Baby icon.png
The Peeper Collectible The Peeper Rebirth icon.png Collectible The Peeper icon.png
Pentagram Collectible Pentagram Rebirth icon.png Collectible Pentagram icon.png
Piggy Bank Collectible Piggy Bank Rebirth icon.png Collectible Piggy Bank icon.png
Polyphemus Collectible Polyphemus Rebirth icon.png Collectible Polyphemus icon.png
Proptosis Collectible Proptosis Rebirth icon.png Collectible Proptosis icon.png
Pyro Collectible Pyro Rebirth icon.png Collectible Pyro icon.png
Rainbow Baby Collectible Rainbow Baby Rebirth icon.png Collectible Rainbow Baby icon.png
Robo-Baby Collectible Robo-Baby Rebirth icon.png Collectible Robo-Baby icon.png
Robo-Baby 2.0 Collectible Robo-Baby 2.0 Rebirth icon.png Collectible Robo-Baby 2.0 icon.png
Rotten Baby Collectible Rotten Baby Rebirth icon.png Collectible Rotten Baby icon.png
Sacrificial Dagger Collectible Sacrificial Dagger Rebirth icon.png Collectible Sacrificial Dagger icon.png
Sad Bombs Collectible Sad Bombs Rebirth icon.png Collectible Sad Bombs icon.png
Sagittarius Collectible Sagittarius Rebirth icon.png Collectible Sagittarius icon.png
Sister Maggy Collectible Sister Maggy Rebirth icon.png Collectible Sister Maggy icon.png
Skeleton Key Collectible Skeleton Key Rebirth icon.png Collectible Skeleton Key icon.png
SMB Super Fan Collectible SMB Super Fan Rebirth icon.png Collectible SMB Super Fan icon.png
Spear of Destiny File:Collectible Spear of Destiny Afterbirth icon.png File:Collectible Spear of Destiny icon.png
Speed Ball Collectible Speed Ball Rebirth icon.png Collectible Speed Ball icon.png
Spirit of the Night Collectible Spirit of the Night Rebirth icon.png Collectible Spirit of the Night icon.png
Strange Attractor Collectible Strange Attractor Rebirth icon.png Collectible Strange Attractor icon.png
Taurus Collectible Taurus Rebirth icon.png Collectible Taurus icon.png
Tech.5 Collectible Tech.5 Rebirth icon.png Collectible Tech.5 icon.png
Tough Love Collectible Tough Love Rebirth icon.png Collectible Tough Love icon.png
Whore of Babylon Collectible Whore of Babylon Rebirth icon.png Collectible Whore of Babylon icon.png
Collectible Ball of Bandages icon.pngBall of Bandages
  • Decreased the damage rate of level 3 and 4 to match Cube of Meat.
Collectible The Battery icon.pngThe Battery
  • Self-recharging active items can charge the yellow meter, allowing Isaac to use them twice immediately.
Collectible Betrayal icon.pngBetrayal
  • No longer triggers if there are fewer than 2 enemies in the room.
  • Its costume has color alts.
Collectible BFFS! icon.pngBFFS!
  • Increases spawner familiar spawn rates.
Collectible Black Candle icon.pngBlack Candle
  • Makes the darkness from Curse of Darkness fade away instead of immediately lighting the room up.
Collectible The Body icon.pngThe Body
  • Its costume has color alts.
Collectible BOGO Bombs icon.pngBOGO Bombs
  • Its costume has color alts.
Collectible Bursting Sack icon.pngBursting Sack
  • Its costume has color alts.
Collectible Cancer icon.pngCancer
  • Its costume has color alts.
Collectible Dead Eye icon.pngDead Eye
  • The multiplier will no longer be lost when hitting poops or TNT barrels.
Collectible E. Coli icon.pngE. Coli
  • Poops spawned react to damage similarly to regular poops.
Collectible Eden's Blessing icon.pngEden's Blessing
  • Is now limited to a maximum of 10 to prevent potential crashes.
Collectible Epiphora icon.pngEpiphora
  • Being hit, changing rooms, and using items no longer reset the Epiphora bonus.
    • During the delay when transitioning between rooms, picking up an item, or using an active item, it's possible to change firing direction without resetting the bonus.
Collectible Fate icon.pngFate
  • Its costume has color alts.
Collectible Fruit Cake icon.pngFruit Cake
Collectible Gemini icon.pngGemini
  • Added extra familiar animations.
Collectible Hive Mind icon.pngHive Mind
  • The effect also applies to locusts.
Collectible Holy Grail icon.pngHoly Grail
  • Its costume has color alts.
Collectible Holy Mantle icon.pngHoly Mantle
  • The shield is no longer restored if the player saves and continues after losing it.
Collectible Immaculate Conception icon.pngImmaculate Conception
  • Its costume has color alts.
Collectible Key Piece 1 icon.pngKey Piece 1 / Collectible Key Piece 2 icon.pngKey Piece 2
Collectible Kidney Stone icon.pngKidney Stone
  • Causes Isaac to fire "tears" from the middle instead of from his eyes, and at a slightly lower height.
Collectible Lil Brimstone icon.pngLil Brimstone
  • Got renamed from "Lil' Brimstone" to "Lil Brimstone".
  • Can damage Fire Places and poops.
Collectible Lil Haunt icon.pngLil Haunt
  • Got renamed from "Lil' Haunt" to "Lil Haunt".
Collectible Lord of the Pit Afterbirth+ icon.pngLord of the Pit
  • Its costume has color alts.
Collectible Lost Contact Rebirth icon.pngLost Contact
  • Only affects the player and Incubus's tears.
Collectible Lusty Blood icon.pngLusty Blood
  • Its costume has color alts.
Collectible Number One icon.pngNumber One
  • Causes Isaac to fire "tears" from the middle instead of from his eyes, and at a slightly lower height.
Collectible Ouija Board icon.pngOuija Board
  • Its costume no longer overwrites the player's skin color to pink instead of white.
Collectible PHD icon.pngPHD
  • Converts:
    • ??? into Telepills
    • Addicted into Percs!
    • Paralysis into Pheromones
    • Retro Vision into I can see forever!
    • R U A Wizard? into Power Pill!
    • X-Lax into Something's wrong...
Collectible Piggy Bank icon.pngPiggy Bank
  • Its costume has color alts.
Collectible Purity icon.pngPurity
  • Better visualization of Purity's glow.
Collectible Restock icon.pngRestock
  • Purchasing an item that is on sale will replace it with another that is on sale.
Collectible Robo-Baby Afterbirth+ icon.pngRobo-Baby
Collectible Rubber Cement icon.pngRubber Cement
  • Tears bounce off bombs.
  • Spectral tears no longer bounce off rocks.
Collectible Sagittarius icon.pngSagittarius
  • Its costume has color alts.
Collectible Scatter Bombs icon.pngScatter Bombs
  • Bombs actually scatter around.
  • Small bombs leave smaller craters.
Collectible The Small Rock icon.pngThe Small Rock
  • The speed and tears changes will take effect immediately. Without Afterbirth+, they didn't immediately change until Isaac's speed or tears stats are updated the next time.
Collectible Steam Sale icon.pngSteam Sale
  • Items have a chance to be discounted further by random sales; for example, a discounted item originally costing 5 coins will then cost 2 coins instead of 3.
Collectible Sticky Bombs icon.pngSticky Bombs
  • Its costume has color alts.
Collectible Succubus icon.pngSuccubus
Collectible Synthoil icon.pngSynthoil
  • Its costume has color alts.

Trinkets

General
  • Some sprites changed:
Item Old sprite New sprite
???'s Soul Trinket Blue Baby's Soul Rebirth icon.png Trinket Blue Baby's Soul icon.png
Black Feather Trinket Black Feather Afterbirth icon.png Trinket Black Feather icon.png
Blasting Cap Trinket Blasting Cap Afterbirth icon.png Trinket Blasting Cap icon.png
Blister Trinket Blister Afterbirth icon.png Trinket Blister icon.png
Bob's Bladder Trinket Bob's Bladder Afterbirth icon.png Trinket Bob's Bladder icon.png
Broken Magnet Trinket Broken Magnet Rebirth icon.png Trinket Broken Magnet icon.png
Brown Cap Trinket Brown Cap Afterbirth icon.png Trinket Brown Cap icon.png
Cain's Eye Trinket Cain's Eye Rebirth icon.png Trinket Cain's Eye icon.png
Cracked Dice Trinket Cracked Dice Afterbirth icon.png Trinket Cracked Dice icon.png
Daemon's Tail Trinket Daemon's Tail Rebirth icon.png Trinket Daemon's Tail icon.png
Endless Nameless Trinket Endless Nameless Afterbirth icon.png Trinket Endless Nameless icon.png
Error Trinket Error Afterbirth icon.png Trinket Error icon.png
Karma Trinket Karma Afterbirth icon.png Trinket Karma icon.png
Lazy Worm Trinket Lazy Worm Afterbirth icon.png Trinket Lazy Worm icon.png
Lil Larva Trinket Lil Larva Afterbirth icon.png Trinket Lil Larva icon.png
Louse Trinket Louse Afterbirth icon.png Trinket Louse icon.png
Lucky Rock Trinket Lucky Rock Rebirth icon.png Trinket Lucky Rock icon.png
Mom's Locket Trinket Mom's Locket Afterbirth icon.png Trinket Mom's Locket icon.png
Mom's Pearl Trinket Mom's Pearl Rebirth icon.png Trinket Mom's Pearl icon.png
Mysterious Paper Trinket Mysterious Paper Rebirth icon.png Trinket Mysterious Paper icon.png
NO! Trinket NO! Afterbirth icon.png Trinket NO! icon.png
Poker Chip Trinket Poker Chip Afterbirth icon.png Trinket Poker Chip icon.png
Purple Heart Trinket Purple Heart Rebirth icon.png Trinket Purple Heart icon.png
Push Pin Trinket Push Pin Rebirth icon.png Trinket Push Pin icon.png
Rainbow Worm Trinket Rainbow Worm Afterbirth icon.png Trinket Rainbow Worm icon.png
Rib of Greed Trinket Rib of Greed Afterbirth icon.png Trinket Rib of Greed icon.png
Second Hand Trinket Second Hand Afterbirth icon.png Trinket Second Hand icon.png
Shiny Rock Trinket Shiny Rock Afterbirth icon.png Trinket Shiny Rock icon.png
Stud Finder Trinket Stud Finder Afterbirth icon.png Trinket Stud Finder icon.png
Super Magnet Trinket Super Magnet Afterbirth icon.png Trinket Super Magnet icon.png
Tape Worm Trinket Tape Worm Afterbirth icon.png Trinket Tape Worm icon.png
Umbilical Cord Trinket Umbilical Cord Rebirth icon.png Trinket Umbilical Cord icon.png
Watch Battery Trinket Watch Battery Afterbirth icon.png Trinket Watch Battery icon.png
Whip Worm Trinket Whip Worm Rebirth icon.png Trinket Whip Worm icon.png
The Left HandThe Left Hand
Safety ScissorsSafety Scissors
TickTick

Interactions

Pickups

General

Hearts

Black Heart
  • Has unique sounds.
Eternal Heart
  • Takes half a heart worth of damage from any lethal hit taken with only Soul Hearts.
Gold Heart
  • Turns nearby enemies to gold when breaking.
  • Added better visual feedback when breaking.
  • Minimap icon added.
  • Has unique sounds.
Half Red Heart
  • Minimap icon added.

Coins

Lucky Penny
  • Has a green shine.

Bombs

Golden Bomb
  • Has unique sounds.

Pills

Friends Till The End!
  • Has narration.

Cards and Runes

? Card? Card
  • Its card ID is 48 instead of 43.
A Card Against HumanityA Card Against Humanity
  • Has a unique card back.
Chaos CardChaos Card
  • Has a unique card back.
Credit CardCredit Card
  • Has a unique card back.
Get out of Jail Free CardGet out of Jail Free Card
  • Has a unique card back.

Chests

General
  • Items dropped no longer revert to their generic stone pedestal look upon leaving and reentering the room.
Locked Chest
Spiked Chest

Entities

Monsters

General
  • Champion enemies no longer deal contact damage if the non-champion version doesn't.
  • Charmed enemies prioritize non-charmed enemies unless there aren't any.
  • Permanently charmed enemies no longer try to go after Punching Bag.
  • Permanently charmed enemies can shoot projectiles through each other and familiars.
  • Monster replacements will now only occur with enemies spawned as part of the room layout.
Begotten
  • Is chained to an adjacent rock if the nearest wall is more than 1 grid cell away.
Big Spider
Blue Gaper
  • Reduced Base HP and added stage HP.
  • Has a proper appearance animation if spawned by a room rather than by a boss.
Conjoined Fatty
  • Added extra sounds and effects to creep attacks.
Death's Head
  • No longer deals contact damage during its death animation.
Greed Gaper
  • Has a proper appearance animation if spawned by a room rather than by a boss.
Homunculus
  • Is chained to an adjacent rock if the nearest wall is more than 1 grid cell away.
Lil Haunt
  • Is no longer considered a boss.
  • Has a unique death portrait.
Lump
Meatball
  • Added extra sounds and effects to creep attacks.
Mega Clotty
  • Make a sound when stomping.
Rage Creep
  • Its brimstone is no longer moved upwards and no longer causes the player to take damage along the top wall in Womb/Utero room #202.
  • Its attack animation slightly longer.
Spider
Stone Grimace and all its variants
Stone Grimace
  • Closes its eyes when the room is cleared.
  • No longer respawn when reentering the room if killed.
Super Pooter
  • Renamed from "Fat Fly" to "Super Pooter".

Mini-Bosses

Greed
  • The Greed fight before Ultra Greed triggers the victory jingle when cleared.
Stone Grimace
  • No longer plays its appear animation if encountered in an already cleared room.
Super Greed
Swinger
  • Spawns with its head retracted and extends over 2 seconds.

Bosses

Brownie
The Cage
  • Its grey creep blinks.
The Forsaken
  • Moves to a more appropriate place to perform his Brimstone attack in L-shaped rooms.
  • Multiple Forsakens in the same room can spawn their own Bony each and always spin their Brimstone attack in the same direction at the same speed.
The Haunt
  • Champion variants are transparent during their first phase.
Hush
  • Due to the way entity stacking works ??? may rarely appear instead and once defeated will skip "phase 2" entirely and will give a completion mark as if Hush was defeated.
Krampus
  • Does a short dash towards the player before doing a spinning Brimstone attack.
  • Can shoot Brimstone lasers in all 4 diagonal directions.
The Lamb
  • No longer do its rotating Brimstone attack when close to a wall.
Little Horn
  • Has new champion versions:
    • Orange: Spits out an orange Troll Bomb instead of a black ball. The bomb deals contact damage and leave a patch of fire similar to Hot Bombs.
    • Black: Does not attack with Pits or troll bombs, but fires smoke balls more frequently.
Mega Satan
  • If The Void is unlocked, there is a 50% chance that the game will not immediately end, and Mega Satan will instead drop an ending chest along with a portal. Entering the chest ends the game and plays the cutscene while entering the portal will take Isaac to The Void.
Mom
  • Familiars are teleported to the player's position when entering the boss room.
Rag Man
  • Has new champion versions:
    • Black: Spawns 2 spiders instead of a Ragling. Uses his resurrect frequently. This won't resurrect anything since the spiders don't leave corpses but still heals him. Sprays tears during his resurrection, similar to Monstro's spit.
    • Red: No longer fires tears. Can have up to 4 Raglings at one time and can revive up to 2 Raglings at once.
Triachnid
  • Has a death animation.

Creeps

Red creep

Environment

General
  • Added some backdrop tiling fixes.
  • Pit seams are fixed.

Chapters

Womb
  • Womb trapdoors have a new sprite for when they are closed.
???
  • Additionally, an exit will spawn in the corner of the room, containing a Portal leading to The Void.
Cathedral
  • Has a new floor transition animation.
  • Some rooms contain Angel Statues that can be bombed to summon the Angels and acquire key pieces.

Rooms

Treasure Room
  • There is a chance that 2-3 Greed Gapers may appear in the room.
  • Treasure rooms can rarely contain two items that can both be taken or poop, trinket, and a couple of pickups instead of an item.
  • New layouts:

Treasure Room 31.pngTreasure Room 32.pngTreasure Room 33.pngTreasure Room 34.pngTreasure Room 35.pngTreasure Room 36.pngTreasure Room 37.pngTreasure Room 38.pngTreasure Room 39.png

Shop
  • There is a 20% chance for Donation Machine to be replaced by Restock Machine.
  • There is a small chance for the shop to be replaced by one of its two rare variants:

Shop 7.pngShop 6.png (the two pennies are lucky pennies)

Curse Room
  • Can contain a Devil statue and a random item, surrounded by spikes.
  • Minimap icon changed.
Sacrifice Room
  • Minimap icon changed.
  • New layout:

Sacrifice Room 10.png

Secret Room
Devil Room
  • Can contain:
  • Urns may spawn in the Devil Room.
  • An angel statue can rarely substitute the Satan statue and can be awoken with an explosion.
    • Angels spawned in this way do not drop Key Pieces.
  • Red Chests inside a Devil Room no longer teleport the player to the Devil Room.
Angel Room
  • Can contain 5 Soul Hearts.
  • Two angel statues can appear in the same room, allowing Isaac to fight both Uriel and Gabriel. It is possible to get both Key Pieces if Isaac awakes and fights each of them one by one; however, fighting both at once will only spawn one Key Piece corresponding to the last defeated angel.
Dice Room
  • The 1 pip room re-rolls each of Isaac's passive items into a random item from the specific item pool where it was acquired.
  • The 4 pips room rerolls item pedestals located in the Shop and the Library.
  • Have a small icon in the corner of the room that denotes what the effect of the room is.
I AM ERROR
Boss Rush
  • There is a small chance that there will be 8 items to choose from.
  • Using the Black Rune will start the Boss Rush.
  • New layout:

Boss Rush 6.png

Crawl Space
  • New layouts (rares):

ItemDungeon 10.pngItemDungeon 11.png

Black Market
  • Players can no longer access the Black Market through the wall glitch. However, it is still possible to access the Black Market using the glitch via special circumstances including having Ipecac and The Inner Eye.

Obstacles

Mushrooms
Reward Plate
  • Locks the room when spawning enemies.
Pressure Plate
  • No longer grants a charge when bombing out of its room.
Movable TNT
  • Takes damage exactly like their regular counterparts.
Spikes
  • No longer stay in their raised position when clearing Pressure Plate rooms.
  • Start (and remain) in their lowered position when entering a cleared Pressure Plate room.

Machines

Donation Machine
  • Donation gradually accelerates if the player stays in contact with the donation machine.
Greed Donation Machine
  • No longer jams when the HUD displays a jamming rate of 0%.
  • Donation gradually accelerates if the player stays in contact with the greed machine.
Slot Machine
  • Items dropped no longer revert to their generic stone pedestal look upon leaving and reentering the room.

Challenges

  • Killing Delirium will count as completing challenges.
I RULE!

Achievements

General
  • Popups can be fast-forwarded by tapping Start.


New bugs/Fixed bugs

Bug Bug! If an angel statue is broken inside the devil room the door will incorrectly be shown to be open, but can't be escaped from
Bug Bug! When Scolex is slowed, some of his body parts may detach or won't even show up - they will only be visible while entering the ground (especially the tail).