Flooded Caves

The Flooded Caves is one of the environments in chapter 2 added in The Binding of Isaac: Afterbirth. The theme of the Flooded Caves is water; as such, most of the enemies inhabiting it are airborne, such as One Tooth and flies, and many of them shoot projectiles, while there are fewer ground-bound and contact-damage-reliant enemies. Some enemies like the Hive have a chance to be replaced with their drowned variants and rocks have a chance to be replaced with water-filled pits.

The Flooded Cave's alternate floors are the Caves and the Catacombs.

After A Secret Exit is unlocked, a boarded door similar to the one leading to a Bedroom will appear in this floor's Boss Room upon defeating the boss, leading to the Mines / Ashpit. This door, like a Bedroom, requires two bombs to be opened. Unlike Angel Rooms and Devil Rooms, this door never disappears.

Though there is some overlap with Downpour due to both featuring water flooding, Downpour's unique enemies are often ghostly and supernatural in nature as opposed to the Flooded Cave's theme of drowned or bloated enemies.

The Flooded Caves are unlocked by defeating It Lives 16 times.

Killing Dogma and The Beast also increases this tally, as does Mausoleum's version of Mom's Heart.

Monsters

Entity	ID	Description
Boil	30.0	Stationary enemy that decreases in size when hit, but regenerates to its full size until fully destroyed. Fires multiple short-ranged blood projectiles in random directions when fully swollen.
Gut	30.1	Stationary enemy that decreases in size when hit, but regenerates to its full size until fully destroyed. Fires Ipecac shots in random directions when fully swollen.
Sack	30.2	Stationary enemy that decreases in size when hit, but regenerates to its full size until fully destroyed. Occasionally spawns Spiders when fully swollen.
Bony	227.0	Wanders around the room and throws a bone at Isaac when he is in sight.
Clotty	15.0	Randomly wanders around the room, firing 4 blood shots in the cardinal directions.
Clot	15.1	Randomly wanders around the room, firing 4 tar shots in the ordinal directions.
I.Blob	15.2	Randomly wanders around the room, firing 8 shots in all directions.
Dip	217.0	Slowly dashes in random directions, dealing contact damage.
Squirt	220.0	Dashes towards Isaac and deals contact damage. Spawns 2 Dips upon death.
Embryo	77.0	Aimlessly hops around the room, dealing contact damage.
Fatty	208.0	Slowly walks towards Isaac. Occasionally farts, which pushes Isaac and adjacent enemies away.
Pale Fatty	208.1	Slowly walks towards Isaac. Occasionally farts and shoots 6 blood shots in all directions. Has a chance to turn into a Blubber upon death.
Blubber	210.0	Walks around aimlessly and randomly spews a cluster of blood shots in all directions. Has a chance to turn into a Half Sack when killed.
Half Sack	211.0	Wanders around aimlessly and leaves a trail of Red Creep.
Fly	13.0	Hovers in place. Does not deal contact damage and is harmless, but can turn into Pooters if they stay around Poop.
Attack Fly	18.0	Red fly that follows Isaac and deals contact damage.
Ring Fly	222.0	Gathers with any other Ring Flies in the room. These flies orbit around themselves while following Isaac. Deals contact damage.
Moter	80.0	Follows Isaac, similar to Attack Flies. Deals contact damage. Splits into 2 Attack Flies upon death.
Eternal Fly	96.0	Invulnerable fly that circles Corny Poop and various monsters. Deals contact damage. Turns into a vulnerable Attack Fly after the object or monster it circles is destroyed.
Level 2 Fly	214.0	Flies toward Isaac erratically, dealing contact damage.
Boom Fly	25.0	Flies across the room in straight diagonal lines, dealing contact damage. Explodes upon death.
Red Boom Fly	25.1	Flies across the room in straight diagonal lines, dealing contact damage. Creates a ring of 6 blood shots upon death.
Full Fly	249.0	Flies toward Isaac erratically, dealing contact damage. Releases 6 bullets in all directions upon death.
Pooter	14.0	Slowly drifts toward Isaac, occasionally firing a single blood shot at him. Does not deal contact damage.
Super Pooter	14.1	Slowly drifts toward Isaac, occasionally firing two blood shots in a V-formation at him. Does not deal contact damage.
Sucker	61.0	Flies slowly towards Isaac, exploding into 4 shots in the cardinal directions upon death.
Gurgle	87.0	Walks towards Isaac, dealing contact damage and periodically firing Ipecac shots at him; they are immune to this explosion, but other enemies are not. Can turn into a Splasher upon death.
Skinny	226.0	Slowly walks towards Isaac, leaving short-lasting Red Creep behind itself.
Rotty	226.1	Slowly walks towards Isaac, leaving short-lasting Red Creep behind itself. Spawns a Bony or two Attack Flies upon death.
Globin	24.0	Chases Isaac, dealing a full heart of contact damage. Upon taking enough damage, it collapses into a pile of goo, which can be killed. Will regenerate after a short period of time if not killed quickly.
Gazing Globin	24.1	Quickly chases Isaac, dealing a full heart of contact damage. Upon taking enough damage, it collapses into a pile of goo, which will slide away from Isaac and can be killed. Will regenerate after a short period of time if not killed quickly.
Grub	239.0	Erratically moves around the room like Larry Jr. and charges at Isaac when he gets within its line of sight. Spawns Maggots, Chargers, or Spitties upon death, one for each of its segments.
Gurgling	237.0	Charges towards Isaac when he lines up with them, leaving a trail of Red Creep and shooting 6 blood shots.
Hopper	29.0	Slowly hops around the room, doing contact damage. Can turn into a Flaming Hopper by jumping into Fire Places or other fires.
Flaming Hopper	54.0	Quickly hops around the room, doing contact damage. Covers a larger distance than the regular Hopper.
Leaper	34.0	Hops around the room, doing contact damage. Occasionally jumps high into the air, dropping down onto Isaac's position while firing 4 blood shots in the cardinal directions.
Psychic Horf	248.0	Stationary enemy that fires a homing shot at Isaac when he gets in range of them.
Host	27.0	Stationary enemy that is normally invulnerable. Raises its head up when Isaac gets close, revealing a fleshy stem that can be damaged. Upon raising its head, it will fire 3 blood shots in a spread and lower its head again.
Red Host	27.1	Stationary enemy that can be damaged even when its head is lowered. Fire 5 spread blood shots when it raises its head.
Mobile Host	204.0	Acts like the Host, but follows Isaac and deals contact damage.
Flesh Mobile Host	247.0	Acts like the Red Host, but follows Isaac and deals contact damage.
Knight	41.0	Moves erratically around the room and charges towards Isaac when in line of sight. Can only be damaged from behind.
Maggot	21.0	Aimlessly moves around the room, dealing contact damage.
Charger	23.0	Slowly moves around the room, charging at Isaac when he gets in its line of sight.
Spitty	31.0	Slowly moves around the room, occasionally firing a single blood shot forward.
Conjoined Spitty	243.0	Slowly moves around the room, occasionally firing a blood shot from both ends of its body.
Maw	26.0	Slowly floats towards Isaac, firing a blood shot at him when he is in their range.
Red Maw	26.1	Floats quickly towards Isaac and releases 4 blood shots in the cardinal directions upon death.
Psychic Maw	26.2	Slowly floats towards Isaac, firing homing shots at him when he is in their range. Spawns with an Eternal Fly orbiting around it.
Mr. Maw	35.0	Walks towards Isaac and attacks by launching its head towards him. Turns into a Maw or Gusher upon death depending on the killed body segment. Occasionally separates at will.
Hive	22.0	Wanders around the room, avoiding Isaac and spawning Attack Flies if he gets close. Spawns a large number of flies on death, which can be Flies, Attack Flies, and/or Pooters.
Nest	205.0	Wanders around the room, avoiding Isaac and spawning Spiders if he gets close. Spawns a Big Spider or Trite upon death.
One Tooth	234.0	Follows Isaac and periodically dashes towards him when it gets close. Deals contact damage.
Splasher	238.0	Walks aimlessly around the room, firing Ipecac shots in random directions.
Round Worm	244.0	Pops out of the ground in random locations and spits a blood shot at Isaac if he is in sight.
Night Crawler	255.0	Pops out of the ground in random locations and fires four short-range shots that spiral outwards if Isaac is in sight.
Spider	85.0	Erratically moves around the room. If Isaac gets close to it, it chases him, trying to deal contact damage.
Big Spider	94.0	Erratically moves around the room. If Isaac gets close to it, it chases him, trying to deal contact damage. Spawns two Spiders upon death.
Ticking Spider	250.0	Crawls around the room erratically, following Isaac and dealing contact damage. Can jump small distances. Explodes upon death.
Trite	29.1	Quickly leaps towards Isaac and deals contact damage.
Ragling	246.0	Quickly leaps towards Isaac and deals contact damage. Randomly shoots two purple shots that orbit around it.
Baby Long Legs	206.0	Runs away from Isaac and frequently spawns Spiders.
Small Baby Long Legs	206.1	Runs away from Isaac and occasionally spawns Sacks.
Crazy Long Legs	207.0	Chases Isaac, dealing touch damage. Occasionally stops to spit 8 blood shots in all directions.
Small Crazy Long Legs	207.1	Chases Isaac, dealing touch damage. Occasionally stops to spit 4 blood shots in the diagonal directions.
Wall Creep	240.0	Crawls along walls to try to line up with Isaac and shoots three blood shots in a line.
Blind Creep	242.0	Randomly crawls along walls and shoots three spread blood shots.
Swarmer	91.0	Slowly floats around the room, spawning several Attack Flies. Spawns Pooters upon taking damage. Spawns a Boom Fly upon death.
Tumor	229.0	Moves around the room diagonally, occasionally firing 6 blood shots in all directions. Fires more often upon getting damaged.
Stone Grimace	42.0	Stationary and invulnerable monster that occasionally fires a blood shot at Isaac. Stops firing when room is cleared.
Constant Stone Shooter	202.0	Stationary and invulnerable monster that continuously fires shots in a single direction.
Gaping Maw	235.0	Stationary and invulnerable monster that sucks Isaac towards it, along with Isaac's tears and enemy projectiles.
Slide	44.1	Quickly slides towards Isaac when he gets in its line of sight, then moves slowly back to its original position. Cannot be destroyed.
Wall Hugger	218.0	Moves around the room like Guts, damaging Isaac by contact. Cannot be destroyed.
Blue Boil	298.0	Stationary enemy that decreases in size when hit, but regenerates to its full size until fully destroyed. Fires 1-3 blood shots towards Isaac when fully swollen.
Corn	217.1	Quickly dashes in random directions, dealing contact damage.
Dank Squirt	220.1	Dashes towards Isaac and deals contact damage, creating slowing black creep. Spawns 2 Clots upon death.
Conjoined Fatty	257.0	Slowly walks towards Isaac. Occasionally pauses to fart out a line of damaging Green Creep towards Isaac. Chance to turn into a regular Fatty upon death.
Swarm	281.0	Follows Isaac in large, tightly-clustered groups and deals contact damage.
Dart Fly	256.0	Flies towards Isaac and attempts to predict his movements. Deals contact damage.
Drowned Boom Fly	25.2	Flies across the room in straight diagonal lines, dealing contact damage. Upon death, explodes and fires four blood shots in the cardinal directions. Also has a chance to spawn a Drowned Charger upon death.
Greed Gaper	299.0	Walks towards Isaac, dealing contact damage.
Blue Gaper	297.0	Walks towards Isaac, dealing contact damage.
Blue Boil	298.0	Stationary enemy that decreases in size when hit, but regenerates to its full size until fully destroyed. Fires 1-3 blood shots towards Isaac when fully swollen.
Drowned Charger	23.1	Slowly moves around the room, charging at Isaac when he gets in its line of sight. Explodes into four blood shots in the ordinal directions upon death.
Drowned Hive	22.1	Wanders around the room, avoiding Isaac and spawning Drowned Chargers if he gets close. Spawns 0-2 Drowned Chargers upon death.
Dukie	288.0	Flies around the room diagonally, occasionally spitting out 1-2 Dart Flies.
Fat Bat	258.0	Slowly flies towards Isaac. Tries to align itself diagonally to Isaac and shoots at him when in that alignment.
Roundy	276.0	Pops out of the ground in random locations, creating a small rock wave. Fires an explosive Ipecac shot at Isaac if he is in sight.
Ulcer	289.0	Pops out of the ground in random locations and spawns a Dart Fly if Isaac is in sight. Fires a blood shot after spawning 6 Dart Flies.
Corn Mine	295.0	Goes off when destroyed or after some time, then releases a cloud of poisonous gas and fires corny shots in eight directions.
Dark Ball	404.1	Floats towards Isaac, doing contact damage.
Mr. Red Maw	35.2	Walks towards Isaac and attacks by launching its head towards him. Turns into a Red Maw or Gusher upon death depending on the killed body segment. Occasionally separates at will.
Mr. Mine	311.0	Can only appear in pits. Attempts to launch itself at Isaac if he comes near. Occasionally burrows and pops up in another pit, and fires six shots in all directions upon death.
Stoney	302.0	Chases Isaac and blocks tears, but does not deal contact damage. Temporarily pauses in exhaustion after a certain amount of time. Invulnerable; dies when the room is cleared.
Ministro	305.0	Hops around randomly and hop towards Isaac when he gets close, occasionally spitting out a cluster of disorganized shots.
Mushroom	300.0	Stationary enemy that occasionally pops up and fires four shots in the cardinal or diagonal directions. Takes less damage while its head is down.
Tube Worm	244.1	Pops out of the ground in random locations and fires a long-range spray of arcing shots where Isaac will be.
Cross Stone Shooter	202.10	Stationary and invulnerable monster that continuously fires shots in four directions, alternating between cardinal and ordinal.
Portal	306.0	Spawns various enemies from the current floor until it either vanishes or is killed.
Bloaty	879.0	Lumbers around, occasionally spitting green shots and a line of damaging green creep in a random direction.
Bulb	61.5	Flies in erratic, angled movements toward Isaac if his active item has charges; on contact, they drain up to 2 charges, but never deal contact damage. If he has no active item, or no charges, they wander around the room aimlessly.
Faceless	827.0	Wanders around the room, rarely firing a radial burst of six shots. Chases Isaac and fires shots more frequently after taking damage.
Needle	881.0	Pops out of the ground and lunges towards Isaac, dealing contact damage.
Pasty	881.1	Pops out of the ground and lunges toward Isaac, dealing contact damage and firing four shots in the ordinal directions.
Prey	817.0	Wanders around the room, avoiding Isaac and spawning Small Leeches if he gets close. Spawns 3 Small Leeches upon death.
Willo	808.0	Flies in a circle around Isaac (in formation with other Willos if available), keeping an exact distance away from him. One Willo at a time will occasionally light up and fire a shot at Isaac.