Soul of Bethany

Soul Stones

• Soul of Isaac
• Soul of Magdalene
• Soul of Cain
• Soul of Judas
• Soul of ???
• Soul of Eve
• Soul of Samson
• Soul of Azazel
• Soul of Lazarus
• Soul of Eden
• Soul of the Lost
• Soul of Lilith
• Soul of the Keeper
• Soul of Apollyon
• Soul of the Forgotten
• Soul of Bethany
• Soul of Jacob and Esau

Soul of Bethany is an unlockable rune added in The Binding of Isaac: Repentance.

Effects

• Spawns 6 blue wisps.
  • Each wisp has its own 10% chance to instead be a random wisp.

Synergies

• BFFS!: Doubles the base damage, contact damage, and damage scaling per floor of the wisps.
• Forgotten Lullaby: Doubles the wisps' fire rate.
• Baby-Bender: Wisp shots become homing shots.

The Binding of Isaac: Rebirth
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