Item Tags summonable
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Items with this tag can be spawned as wisps by Lemegeton and copied by Modeling Clay .
Passive Collectibles
Name | ID | Icon | Quote | Description | Quality |
---|---|---|---|---|---|
???'s Only Friend | 5.100.320 | Controlled friend | Spawns a controllable familiar that deals 37.5 damage per second on touch. It can be moved using the shooting directional keys | 1 | |
20/20 | 5.100.245 | Double shot | Isaac fires two tears at once, one from each eye. 0.8× damage multiplier. | 4 | |
3 Dollar Bill | 5.100.191 | Rainbow tears | Gives Isaac a random tear effect every room. Gives Isaac a random tear effect every few seconds. |
2 | |
9 Volt | 5.100.116 | Quicker charge | Reduces the charge of any activated item by 1. Any 1 charge items instead have timed recharges. | 2 | |
A Lump of Coal | 5.100.132 | My Xmas present | The more distance tears travel, the more damage they will do. | 3 | |
Abaddon | 5.100.230 | Evil + DMG up + fear shot | +1.5 damage, +0.2 speed. Removes all Red Heart containers, grants six Black Hearts, and adds a chance to shoot fear tears. +1.5 damage, +0.2 speed. Grants two Black Hearts, converts all Red Heart Containers into Black Hearts, and adds a chance to shoot fear tears. |
3 | |
Abel | 5.100.188 | Mirrored buddy | Spawns a familiar that mirrors Isaac's movements and shoots in the opposite direction. Spawns a familiar that mirrors Isaac's movements and shoots towards him. |
0 | |
Anemic | 5.100.214 | Toxic blood | After Isaac is damaged, a trail of red creep will be left behind him until he leaves the current room. +5 range. +1.5 range. | 1 | |
Anti-Gravity | 5.100.222 | Anti-gravity tears + tears up | Tears float in position until firing ceases, after which they will fly off in the direction they were shot in. -2 Tear Delay. +1 Fire Rate. | 2 | |
Aquarius | 5.100.308 | Trail of tears | A trail of blue creep is left behind Isaac, which damages enemies. The creep scales with damage and inherits most tear effects. | 2 | |
Aries | 5.100.300 | Ramming speed | +0.25 Speed. Running into enemies while at a high speed will deal damage. Prevents Isaac from taking contact damage while moving at high speed. | 2 | |
Ball of Bandages | 5.100.207 | Gotta lick 'em all! | Creates an orbital familiar. Collecting additional copies gives it the ability to shoot Charm tears, then chase enemies to deal contact damage, then deal even more contact damage. | 2 | |
Ball of Tar | 5.100.231 | Sticky feet... | Adds a chance to shoot slowing tears. Isaac leaves a trail of slowing creep behind as he moves, impeding enemies' speed. | 2 | |
BBF | 5.100.272 | Big Beautiful Fly | Spawns a familiar that flies around the room in a zig-zag pattern and explodes on contact with an enemy. Respawns after ten seconds. | 1 | |
Best Bud | 5.100.274 | Sworn protector | When hit, spawns a quickly orbiting attack fly similar to Forever alone for the current room that deals high damage. | 0 | |
BFFS! | 5.100.247 | Your friends rule! | Increases the size and effectiveness of most familiars. | 2 | |
Big Fan | 5.100.279 | Fat protector | Spawns a large orbital familiar that blocks enemy shots and deals 30 damage per second to enemies. | 2 | |
Black Candle | 5.100.260 | Curse immunity + evil up | Prevents curses. Grants one Black Heart. Increases the chance for a Devil Room or Angel Room to appear. | 3 | |
Blood Clot | 5.100.254 | DMG + range up | Tears fired from the left eye have +1 flat damage, +5 range, and +0.5 tear falling speed. Tears fired from the left eye have +1 flat damage and +2.75 range. |
2 | |
Blood of the Martyr | 5.100.7 | DMG up | +1 damage. Isaac shoots blood tears. | 3 | |
Bloody Lust | 5.100.157 | RAGE! | Increases Isaac's damage whenever he takes damage, up to six times. The bonus resets when entering a new floor. | 2 | |
Blue Cap | 5.100.342 | HP + tears up + shot speed down | Gives one full Red Heart container, +0.7 tears, and -0.16 shot speed. Heals 1 additional Red Heart. | 3 | |
Blue Map | 5.100.246 | Secrets | Reveals the locations of Secret Rooms and Super Secret Rooms on the map. | 2 | |
Bob's Brain | 5.100.273 | Explosive thoughts | Spawns a familiar that charges forward when shooting tears and explodes upon contact with an enemy, damaging and poisoning them. The familiar respawns after a few seconds. | 1 | |
Bob's Curse | 5.100.140 | +5 poison bombs | +5 Bombs. Grants Isaac's bombs a poison effect. They also leave a lingering poison cloud, and Isaac becomes immune to poison. | 1 | |
Bobby-Bomb | 5.100.125 | Homing bombs! | +5 Bombs. Bombs gain a homing effect, slowly moving towards the nearest enemy. | 2 | |
BOGO Bombs | 5.100.250 | 1+1 BOOM! | All normal Bombs become Double Bombs. | 1 | |
Bomb Bag | 5.100.131 | Gives bombs | Spawns a familiar that drops a Bomb every 3 rooms. | 2 | |
Brimstone | 5.100.118 | Blood laser barrage | Tears are replaced with a blood laser beam that pierces through all enemies and obstacles in its path and deals high damage. Can only be fired after a short charge-up period. | 4 | |
Broken Watch | 5.100.337 | I think it's broken | Slows all enemies in every fourth newly-discovered room, with a small chance to speed them up instead. | 1 | |
Brother Bobby | 5.100.8 | Friends 'till the end | Spawns a familiar that follows Isaac around shooting tears that deal 3.5 damage. He shoots more frequently than most familiars. | 1 | |
Bum Friend | 5.100.144 | He's greedy | Spawns a familiar that picks up coins for himself, giving random pickups in return. Can spawn Items from the Beggar Item Pool. | 1 | |
Butt Bombs | 5.100.209 | Toxic blast +5 bombs | +5 Bombs. Bombs now cloud up the screen, briefly damaging and confusing all enemies. | 2 | |
Caffeine Pill | 5.100.340 | Speed up + size down | Grants +0.3 speed, reduces Isaac's size, and gives a random pill. | 1 | |
Cain's Other Eye | 5.100.319 | Near-sighted friend | Spawns a familiar that slowly floats around the room on a zig-zag pattern and shoots normal tears in the same direction as Isaac. Spawns a familiar that follows Isaac and fires tears in random cardinal directions that copy Isaac's tears and tear effects and scale with damage. |
2 | |
Cancer | 5.100.301 | HP up + you feel protected | Adds 3 Soul Hearts. Grants The Wafer effect for the current room after taking damage. | 3 | |
Capricorn | 5.100.307 | All stats up | Adds 1 Red Heart Container, gives +0.5 Damage, +0.1 Speed, +1.5 Range, and -1.0 Tear Delay, and gives 1 Bomb, Penny, and Key. Adds 1 Red Heart Container, gives +0.5 Damage, +0.1 Speed, +0.75 Range, and +0.5 Fire Rate, and gives 1 Bomb, Penny, and Key. |
3 | |
Cat-o-nine-tails | 5.100.165 | Shot speed + damage up | +1 damage, +0.23 shot speed. | 3 | |
Celtic Cross | 5.100.162 | Blessing of protection | Grants a chance to trigger the Book of Shadows effect upon taking damage, creating a shield that nullifies all types of damage for 7 seconds. | 1 | |
Ceremonial Robes | 5.100.216 | DMG + evil up | Grants 3 Black Hearts and +1 damage. | 3 | |
Champion Belt | 5.100.208 | DMG + challenge up | +1 damage. Increases the chance of champion enemies appearing by 15%. | 3 | |
Charm of the Vampire | 5.100.62 | DMG up + kills heal | Heals Isaac for a Half Red Heart for every 13 enemies killed. +0.3 damage. | 1 | |
Chemical Peel | 5.100.154 | DMG up | Tears fired from the left eye have +2 flat damage. | 2 | |
Chocolate Milk | 5.100.69 | Charge shots | Grants charged tears that deal greater damage when fully charged. | 3 | |
Contract From Below | 5.100.241 | Wealth... but at what cost? | Doubles the number of most room clear awards, but reduces the overall chance of getting one by 1/3. | 3 | |
Cricket's Body | 5.100.224 | Bursting shots + tears up | When tears hit an object or deplete their range, they spawn 4 smaller tears, whose range and damage scale with Isaac's. Grants -1 tear delay and reduces range. Grants +0.5 fire rate and reduces range. | 3 | |
Cricket's Head | 5.100.4 | DMG up | Increases Damage by 0.5, and increases damage multiplier by ×1.5. | 4 | |
Cube of Meat | 5.100.73 | Gotta meat 'em all! | Creates an orbital familiar. Collecting additional copies gives it the ability to shoot tears, then chase enemies to deal contact damage, then deal even more contact damage. | 2 | |
Cupid's Arrow | 5.100.48 | Piercing shots | Grants Isaac triangular piercing tears that travel through enemies (but not obstacles) instead of breaking on impact with them. | 3 | |
Cursed Eye | 5.100.316 | Cursed charge shot | Grants charged tears that can be fired in a tight burst. Getting hit while charging will teleport Isaac to another room. | 0 | |
Daddy Longlegs | 5.100.170 | Daddy's love | Daddy Long Legs' shadow follows Isaac and occasionally stomps enemies for 40 damage total. | 3 | |
Dark Bum | 5.100.278 | He wants to take your life | Spawns a familiar that follows Isaac around and collects Red Hearts. For every 1½ Red Hearts collected, Dark Bum will give a reward. | 3 | |
Dark Matter | 5.100.259 | DMG up + fear shot | +1 damage, adds a chance to shoot fear tears. | 3 | |
Dead Bird | 5.100.117 | Protective buddy | After Isaac takes damage, spawns a flying familiar that chases enemies for the current room, dealing ~4 damage per second. | 0 | |
Dead Dove | 5.100.185 | Flight + spectral tears | Grants spectral tears and flight. | 3 | |
Dead Onion | 5.100.336 | Toxic aura tears | Grants piercing and spectral tears. Increases tear size (without increasing damage) while greatly reducing range and shot speed. | 3 | |
Death's Touch | 5.100.237 | Piercing shots + DMG up | +1.5 damage, -0.3 tears. Tears are replaced with large piercing scythes. | 3 | |
Demon Baby | 5.100.113 | Auto-turret friend | Spawns a familiar that follows Isaac and automatically fires at enemies in its reach. | 2 | |
Distant Admiration | 5.100.57 | Attack fly | Spawns an attack fly that circles further out than Halo of Flies, but closer than Forever alone, dealing 75 damage per second. | 2 | |
Dr. Fetus | 5.100.52 | ??? | Tears are replaced by Bombs that benefit from bomb-enhancing effects and slide for a fixed time after being fired. | 4 | |
Dry Baby | 5.100.265 | Immortal friend | Spawns a familiar that follows Isaac around and blocks enemy projectiles. Upon blocking a shot, it has a chance of triggering The Necronomicon effect. | 3 | |
E. Coli | 5.100.236 | Turdy touch | Enemies that touch Isaac are transformed into Poop. | 1 | |
Epic Fetus | 5.100.168 | On-demand air strike | Instead of tears, firing creates a crosshair which can be moved freely. A missile is dropped in the location after 1.5 seconds, exploding for high damage. | 4 | |
Eve's Mascara | 5.100.310 | DMG up, tears + shot speed down | Doubles damage, halves tears stat, and greatly reduces shot speed. Doubles damage, 0.66x tears multiplier, and greatly reduces shot speed. |
3 | |
Fanny Pack | 5.100.204 | Filled with goodies | Has a chance to drop a random pickup when Isaac takes damage. | 1 | |
Fate | 5.100.179 | Flight eternal | Grants flight and one Eternal Heart. | 3 | |
Fire Mind | 5.100.257 | Flaming tears | Grants flaming tears that deal burning damage over time. Tears have a chance to explode on impact with an enemy, which creates a fire at the location of the explosion. | 2 | |
Forever alone | 5.100.128 | Attack fly | Spawns an attack fly that orbits a long distance from Isaac, dealing 30 damage per second. | 1 | |
Gemini | 5.100.318 | Conjoined friend | Spawns a conjoined familiar which chases enemies close to Isaac, dealing ~6.43 damage per second. | 1 | |
Ghost Baby | 5.100.163 | Spectral buddy | Spawns a familiar that follows Isaac around and fires spectral tears. | 1 | |
Gimpy | 5.100.225 | Sweet suffering | Gives chance of spawning a Soul Heart when taking damage. Enemies have a chance to drop a Half Red Heart after being killed. | 2 | |
Gnawed Leaf | 5.100.210 | Unbreakable | After standing still and not shooting for a short time, Isaac turns invincible until he moves or shoots. | 1 | |
Goat Head | 5.100.215 | He accepts your offering | A Devil Room / Angel Room will always spawn after every boss fight, excluding the first floor and floors after Chapter 4. | 3 | |
Godhead | 5.100.331 | God tears | Grants homing tears with a damaging halo. +0.5 Damage, -0.3 Tears -0.3 Shot Speed, +0.8 Tear Falling Speed, and +1.2 Range. Grants homing tears with a damaging halo. +0.5 Damage, -0.3 Tears, and -0.3 Shot Speed. |
4 | |
Growth Hormones | 5.100.70 | Speed + DMG up | +1 damage, +0.4 speed. +1 damage, +0.2 speed. |
3 | |
Guardian Angel | 5.100.112 | Extra protection | Spawns an orbital familiar that blocks enemy shots, deals 7 damage per tick on contact, and increases the speed of all orbital familiars. | 2 | |
Guillotine | 5.100.206 | DMG + tears up. An out-of-body experience! | Isaac's head is removed from his body and floats around him as an orbital. Gives +1 damage and grants -1 tear delay. Gives +1 damage and grants +0.5 fire rate. | 2 | |
Guppy's Hairball | 5.100.187 | Swing it | Spawns a familiar that loosely follows behind Isaac, which blocks shots can be swung like a flail to damage enemies. Grows bigger by killing enemies. | 1 | |
Guppy's Tail | 5.100.134 | Cursed? | Room Clear Awards have a 1/3 chance of being replaced with a Chest and a 2/9 chance being replaced with nothing. | 2 | |
Habit | 5.100.156 | Item martyr | When Isaac is hit, his active item gains 1 room's worth of charge. | 2 | |
Halo of Flies | 5.100.10 | Projectile protection | Spawns two Pretty Flies that block enemy shots and deal contact damage to flies. | 2 | |
Harlequin Baby | 5.100.167 | Double shot buddy | Spawns a familiar that follows Isaac around and fires two tears at once in a V-pattern. | 1 | |
Headless Baby | 5.100.269 | Bloody friend | Spawns a familiar that follows Isaac, leaving blood creep on the ground. | 1 | |
Hive Mind | 5.100.248 | Giant spiders and flies | Increases the size of Blue Spiders and Blue Flies and doubles the amount of damage they deal. Also increases the effectiveness of fly and spider familiars. | 2 | |
Holy Grail | 5.100.184 | Flight + HP up | Grants flight and one Red Heart container. Heals 1 additional Red Heart. | 3 | |
Holy Mantle | 5.100.313 | Holy shield | Grants a shield that negates the first instance of damage taken from a hostile source once per room. | 4 | |
Holy Water | 5.100.178 | Splash! | Spawns a bottle familiar that breaks when Isaac takes damage, leaving a puddle of blue creep. A bottle familiar that flies forward when Isaac shoots. It breaks upon hitting an enemy, leaving a puddle of blue creep that petrifies enemies. |
3 | |
Hot Bombs | 5.100.256 | Burning blast +5 bombs | +5 Bombs. Isaac's bombs leave behind fire that damages enemies upon contact. | 1 | |
Humbleing Bundle | 5.100.203 | 1+1 free 4Evar | Transforms Bombs, Keys, Pennies, and Red Hearts into their respective Double versions. This will occur 50% of the time. | 3 | |
Infamy | 5.100.242 | Blocks damage... sometimes | Gives Isaac a 50% chance to block projectiles coming from any direction. | 2 | |
Infestation | 5.100.148 | Fly revenge | 1-3 Blue Flies randomly spawn every time Isaac gets hit. 2-6 Blue Flies randomly spawn every time Isaac gets hit. |
0 | |
Infestation 2 | 5.100.234 | Infestation shot | Spawns allied Blue Spiders from killed enemies. | 3 | |
Ipecac | 5.100.149 | Explosive shots | Replaces tears with explosive and poisoning projectiles fired in an arc from the mouth. | 4 | |
Iron Bar | 5.100.201 | DMG up + concussive tears | +0.3 damage. Adds a chance to shoot concussive tears, causing enemies to walk around randomly. | 2 | |
Isaac's Heart | 5.100.276 | Protect it | Isaac himself is now immune to all damage, and a heart familiar follows him. If the heart is hurt, Isaac is hurt. The heart charges up as Isaac shoots, firing 8 blood shots, knocking back enemies, and leaving a puddle of creep when released. | 0 | |
Jesus Juice | 5.100.197 | Damage + range up | +0.5 damage, +0.25 range, +0.5 tear falling speed. +0.5 damage, +1.5 range. |
2 | |
Juicy Sack | 5.100.266 | Sticky babies | Spawns a familiar that follows Isaac and drips a trail of slow creep, spawning 1-2 Blue Spiders after each room. | 2 | |
Latch Key | 5.100.343 | Luck up | Grants 1 Soul Heart and +1 luck. Spawns 2 Keys. | 1 | |
Leech | 5.100.270 | Blood sucker | Spawns a leech familiar that chases enemies, dealing ~3 damage per second. Heals a Half Red Heart whenever Leech kills an enemy. | 2 | |
Leo | 5.100.302 | Stompy | Isaac can destroy rocks by walking into them. | 1 | |
Libra | 5.100.304 | You feel balanced | Gives 6 Coins, 6 Bombs, and 6 Keys and balances out all attributes. | 1 | |
Lil Brimstone | 5.100.275 | Evil friend | Grants a familiar that charges a thin Brimstone laser while Isaac is shooting. | 2 | |
Lil Haunt | 5.100.277 | Fear him | Spawns a familiar that chases down enemies, dealing 4 damage per second and inflicting fear. | 1 | |
Little Baggy | 5.100.252 | Extra pill room | Isaac can hold 2 pills at once and all cards and runes are replaced by pills. | 0 | |
Little C.H.A.D. | 5.100.96 | Gives kisses | Spawns a familiar who drops a Half Red Heart every 3 rooms. | 2 | |
Little Chubby | 5.100.88 | Attack buddy | Spawns a Charger familiar that charges forward and deals contact damage to any enemies in its path. | 2 | |
Little Gish | 5.100.99 | Sticky friend | Spawns a familiar that follows Isaac around and fires slowing tears, impeding enemies' speed. | 2 | |
Little Steven | 5.100.100 | Psychic friend | Spawns a familiar who follows Isaac around and fires homing tears. | 2 | |
Loki's Horns | 5.100.87 | Cross tears | Gives a random chance for projectiles to fire in all 4 cardinal directions. | 1 | |
Lord of the Pit | 5.100.82 | Demon wings | Grants flight and +0.3 speed. | 3 | |
Lost Contact | 5.100.213 | Shielded tears | Isaac's tears can hit and destroy enemy projectiles. -0.15 shot speed. | 2 | |
Lucky Foot | 5.100.46 | Luck up | +1 luck. Improves Isaac's chances at various random events (independent from the luck stat). Converts all bad pills into good pills, without identifying them. | 2 | |
Maggy's Bow | 5.100.312 | HP up + you feel healthy | Gives one Red Heart Container and doubles the healing provided by Red Hearts. Also heals 1 Red Heart when obtained. | 2 | |
Magic 8 Ball | 5.100.194 | Shot speed up | +0.16 shot speed, spawns a random tarot card. Increases the chance of finding a Planetarium. | 1 | |
Magic Mushroom | 5.100.12 | All stats up! | Makes Isaac bigger. Adds one Red Heart Container, +0.3 Damage, x1.5 damage multiplier, +5.25 Range, +0.3 Speed, and restores all Health. Makes Isaac bigger. Adds one Red Heart Container, +0.3 Damage, x1.5 damage multiplier, +2.5 Range, +0.3 Speed, and restores all Health. |
4 | |
Magneto | 5.100.53 | Item snatcher | Pulls pickups towards Isaac. | 1 | |
MEAT! | 5.100.193 | DMG + HP up | Grants one full Red Heart container, +0.3 damage. Heals 1 additional Red Heart | 2 | |
Midas' Touch | 5.100.202 | Golden touch | Enemies that touch Isaac are temporarily petrified and turn to gold. Any enemy killed while in this state will drop Pennies. | 2 | |
Mini Mush | 5.100.71 | Speed + range up | Decreases Isaac's size, making him less likely to be hit. +0.3 speed, +1.5 tear falling speed, -4.25 range (effective range is increased). +0.3 speed, +2.5 range. | 2 | |
Missing No. | 5.100.258 | Syntax error | Randomizes all passive items and stats upon pickup and at the start of each succeeding floor. | 0 | |
Missing Page 2 | 5.100.262 | Evil up. Your enemies will pay! | Grants one Black Heart. Upon taking damage that reduces Isaac's health to one heart or less, deals damage to all enemies in the room. Increases the damage of Black Hearts and The Necronomicon-like effects by 40. | 0 | |
Mitre | 5.100.173 | Blessing of purity | Grants a chance of converting any Red Heart pickups that spawn into Soul Hearts instead. | 3 | |
Mom's Contacts | 5.100.110 | Freeze effect | Adds a chance to shoot petrifying tears, which stop enemies in place and prevent them from moving or attacking. +0.25 range. +1.5 range. | 3 | |
Mom's Eye | 5.100.55 | Eye in the back of your head | Gives Isaac a chance to fire tears from the back of his head. | 1 | |
Mom's Eyeshadow | 5.100.200 | Charm tears | Tears have a chance to charm enemies. | 1 | |
Mom's Heels | 5.100.30 | Range up | +5.25 range, +0.5 tear falling speed. +2.5 range, enemies that touch Isaac take 12 damage. |
1 | |
Mom's Key | 5.100.199 | Better chest loot +2 keys | Adds 2 keys. Chests will drop additional pickups. | 3 | |
Mom's Knife | 5.100.114 | Stab stab stab | Isaac's tears are replaced by a knife that pierces enemies, can travel through obstacles, and can hurt enemies while Isaac is holding it. Holding down the fire button before firing increases its range and power. | 4 | |
Mom's Lipstick | 5.100.31 | Range up | +5.25 range, +0.5 tear falling speed. +3.75 range. Spawns a Heart on pickup. |
1 | |
Mom's Perfume | 5.100.228 | Fear shot + tears up | Adds a chance to shoot fear tears. Decreases tear delay by 1. +0.5 fire rate. | 2 | |
Mom's Purse | 5.100.139 | More trinket room | Allows Isaac to hold one additional trinket. Drops a random trinket. | 2 | |
Mom's Underwear | 5.100.29 | Range up | +5.25 range, +0.5 tear falling speed. +2.5 range. Spawns 3-6 Blue Flies on pickup. |
1 | |
Mom's Wig | 5.100.217 | You feel itchy... | Adds a chance to spawn Blue Spiders when firing tears. Restores 1 Red Heart. | 2 | |
Money = Power | 5.100.109 | $$$ = DMG | Increases damage by 0.04 for every coin Isaac has, up to +3.96 damage at 99 coins. | 3 | |
Mongo Baby | 5.100.322 | Mongo friend | Spawns a familiar that copies the tears of Isaac's other familiars. | 2 | |
Monstro's Lung | 5.100.229 | Charged burst attack | Replaces normal tears with a charged shot that fires 14 tears in the same fashion as Monstro. | 2 | |
Mutant Spider | 5.100.153 | Quad shot | Isaac shoots four tears at once with lower fire rate. | 3 | |
My Reflection | 5.100.5 | Boomerang tears + DMG up + luck down | Gives Isaac's tears a boomerang effect. +1.5 range, +1 tear falling speed, x1.6 shot speed multiplier. 2x + 1.5 range, +1.5 damage, -1 luck, 1.6x shot speed multiplier. | 2 | |
Mysterious Liquid | 5.100.317 | Toxic splash damage | Tears leave a small, short lasting pool of creep on impact or when their range is depleted. | 3 | |
Mystery Sack | 5.100.271 | ? | Spawns a familiar that drops a Heart, coin, Bomb, or Key every 5-6 rooms. | 2 | |
Number One | 5.100.6 | Tears up + range down | Grants +1.5 tears, but severely reduces range. | 2 | |
Odd Mushroom | 5.100.121 | HP + DMG up, speed down | Grants one empty Heart container, +0.3 damage, +0.25 range, +0.5 tear falling speed, and -0.1 speed. Grants one full Heart container, +1 damage, +1.5 range, and -0.2 speed |
2 | |
Odd Mushroom | 5.100.120 | Tears + speed up, DMG down | +1.7 tears, +0.3 speed, slightly reduces damage. | 2 | |
Ouija Board | 5.100.115 | Spectral tears + tears up | Grants spectral tears that travel through obstacles (but not enemies). +0.5 tears. | 2 | |
Pentagram | 5.100.51 | DMG up | +1 damage, increases Devil Room / Angel Room chance by 10%. | 3 | |
PHD | 5.100.75 | Better pills | Converts all bad pills into good pills, spawns one pill pickup, and identifies all pills. Restores two Red Hearts and increases the payout of Blood Donation Machines. | 2 | |
Piggy Bank | 5.100.227 | My life savings | Gives 3 Pennies on pick-up. Every time Isaac is damaged, he will drop one or two additional pennies. | 1 | |
Pisces | 5.100.309 | Tears up + knock-back shots | -1 Tear Delay, adds knock-back shots and increases tear size. +0.5 Fire Rate, adds knock-back shots and increases tear size. |
2 | |
Polyphemus | 5.100.169 | Mega tears | Isaac fires huge tears that deal massive damage, but fire rate is greatly decreased. If a tear kills an enemy, it travels on with any leftover damage. | 4 | |
Proptosis | 5.100.261 | Short range mega tears | Tears start out massive with high damage, and then shrink down and become weaker over a short range. | 3 | |
Punching Bag | 5.100.281 | Scape goat | Spawns a Mulligan familiar that wanders randomly. Enemies will attack the Mulligan if it's closer. | 1 | |
Pyromaniac | 5.100.223 | It hurts so good +5 bombs | +5 bombs. Grants immunity to explosion damage and causes explosions to heal Isaac. Also grants immunity to fire. | 4 | |
Rainbow Baby | 5.100.174 | Random buddy | Spawns a familiar that follows Isaac around and fires tears with random effects. | 1 | |
Robo-Baby | 5.100.95 | Friends 'till the bbbbzzzt | Spawns a familiar that shoots Technology lasers. | 1 | |
Robo-Baby 2.0 | 5.100.267 | We worked out all the kinks | Spawns a familiar that fires lasers at any enemy in its line of sight and moves based on the direction Isaac is firing tears. | 1 | |
Roid Rage | 5.100.14 | Speed and range up | +0.6 speed, +5.25 range, +0.5 tear falling speed. +0.3 speed, +2.5 range |
2 | |
Rotten Baby | 5.100.268 | Infested friend | Spawns a familiar that spawns a Blue Fly when Isaac shoots. It can only have one Fly at a time. | 3 | |
Rubber Cement | 5.100.221 | Bouncing tears | Tears bounce off walls, enemies, and environmental objects. | 3 | |
Sack of Pennies | 5.100.94 | Gives money | Spawns a familiar that drops a coin every 2 rooms. | 1 | |
Sacred Heart | 5.100.182 | Homing shots + DMG up | Adds a Red Heart Container. Grants homing tears, a x2.3 Damage multiplier, +1 flat Damage, -0.4 Tears, -0.25 Shot Speed, and +4.125 Range. Adds a Red Heart Container. Grants homing tears, a x2.3 Damage multiplier, +1 flat Damage, -0.4 Tears, and -0.25 Shot Speed. |
4 | |
Sacrificial Dagger | 5.100.172 | My fate protects me | Spawns a dagger orbital familiar, blocking enemy shots and dealing a high amount of damage to enemies in contact. | 2 | |
Sad Bombs | 5.100.220 | Tear blasts +5 bombs | +5 Bombs. Upon exploding, bombs shoot 10 tears around them, affected by tear modifiers. | 2 | |
Safety Pin | 5.100.339 | Evil + range + shot speed up | Grants one Black Heart, +5.25 range, +0.5 tear falling speed, +0.16 shot speed. Grants one Black Heart, +2.5 range, +0.16 shot speed. |
1 | |
Sagittarius | 5.100.306 | Piercing shots + speed up | Increases speed by +0.2 and grants piercing tears. | 3 | |
Samson's Chains | 5.100.321 | The ol' ball and chain | Attaches a ball and chain to Isaac that pulls behind him that damages enemies, blocks shots, and destroys most Obstacles. | 1 | |
Scapular | 5.100.142 | Pray for a miracle | Once per room, when Isaac is reduced to his last half heart, he is granted one Soul Heart. | 2 | |
Scorpio | 5.100.305 | Poison tears | Grants poison tears, which deal damage over time when inflicted. | 3 | |
Screw | 5.100.255 | Tears + shot speed up | +0.5 tears, +0.2 shot speed. | 3 | |
Sharp Plug | 5.100.205 | Infinite charge... at a cost | Damages Isaac in exchange for fully recharging Isaac's current activated item. | 2 | |
Sissy Longlegs | 5.100.280 | She loves you | Spawns a familiar that wanders randomly, occasionally spawning Blue Spiders. Briefly charms enemies on contact. | 1 | |
Sister Maggy | 5.100.67 | Friends 'till the end | Spawns a familiar that follows Isaac around shooting tears that deal 3.5 damage. Spawns a familiar that follows Isaac around shooting tears that deal 6 damage. |
1 | |
Skatole | 5.100.9 | Fly love | Flies become harmless or less dangerous depending on the type. | 0 | |
Smart Fly | 5.100.264 | Revenge fly | Spawns an orbital familiar that blocks enemy shots. Upon taking damage, the familiar will pursue enemies for the rest of the room, dealing 22.5 damage per second. | 2 | |
SMB Super Fan | 5.100.189 | All stats up | +1 Red Heart container, +0.3 damage, +0.2 tears, +0.2 speed, +0.5 range, +1 tear falling speed. Fully restores all red hearts. +1 Red Heart container, +0.3 damage, +0.2 tears, +0.2 speed, +2.5 range. Fully restores all red hearts. |
3 | |
Soy Milk | 5.100.330 | DMG down + tears way up | Tears are smaller and do much less damage, but fire in very rapid succession. | 2 | |
Speed Ball | 5.100.143 | Speed + shot speed up | +0.3 speed, +0.2 shot speed. | 2 | |
Spelunker Hat | 5.100.91 | See-through doors | Reveals type of adjacent rooms, including location for Secret Rooms and Super Secret Rooms. Reveals rooms up to 2 rooms away and blocks projectiles falling from above. | 2 | |
Spider Bite | 5.100.89 | Slow effect | Adds a chance to shoot slowing tears, reducing speed of enemy movement and any projectile fired by them. | 2 | |
Spiderbaby | 5.100.211 | Spider revenge | Spawns 1-2 Blue Spiders when Isaac takes damage. Spawns 3-5 Blue Spiders when Isaac takes damage. |
0 | |
Spirit of the Night | 5.100.159 | Scary | Grants spectral tears and flight. | 3 | |
Spoon Bender | 5.100.3 | Homing shots | Grants Isaac homing tears. | 3 | |
Squeezy | 5.100.196 | Tears up | +0.4 tears, spawns 2 Soul Hearts. | 3 | |
Starter Deck | 5.100.251 | Extra card room | Isaac can hold 2 cards at once and all pills are replaced by cards. | 2 | |
Steam Sale | 5.100.64 | 50% off | Reduces all Shop prices by 50%, rounded down to 7 coins for an item, rounded up to 2-3 coins for a pickup. | 2 | |
Steven | 5.100.50 | DMG up | +1 damage. | 3 | |
Stigmata | 5.100.138 | DMG + HP up | +0.3 damage, grants one full Red Heart container. Heals 1 additional Red Heart. | 2 | |
Stop Watch | 5.100.232 | Let's slow this down a bit... | +0.3 speed. Automatically inflicts slow to all enemies in every room. +0.3 speed. Upon taking damage, inflicts slow to all enemies for the current room. +0.3 speed. Slows all enemies in every room to 80% speed. |
4 | |
Strange Attractor | 5.100.315 | Magnetic tears | Pickups, trinkets, and monsters are magnetically attracted to Isaac's tears. | 0 | |
Synthoil | 5.100.345 | DMG + range up | +1 damage, +5.25 range, +0.5 tear falling speed. +1 damage, +2.5 range. |
3 | |
Taurus | 5.100.299 | Speed down + rage is building | -0.3 Speed. Isaac builds speed while in a room with enemies. At max speed, he gains the My Little Unicorn effect for 5 seconds. | 1 | |
Tech.5 | 5.100.244 | It's still being tested... | Isaac occasionally fires an unlimited range piercing laser alongside his normal tears. The laser can glitch, mimicking the effects of certain items and trinkets. | 3 | |
Technology | 5.100.68 | Laser tears | Replaces tears with a piercing laser with unlimited range. | 3 | |
Technology 2 | 5.100.152 | Extra laser | Replaces the tears fired from Isaac's right eye with a rapid-firing low damage piercing laser. Damage down. | 2 | |
The Battery | 5.100.63 | Stores energy | Activated items can be overcharged, allowing them to store up to one extra use. | 2 | |
The Belt | 5.100.28 | Speed up | +0.3 speed. | 1 | |
The Black Bean | 5.100.180 | Toot on touch | When taking damage, Isaac farts, poisoning enemies in range. When taking damage, Isaac farts five times, poisoning and knocking back nearby enemies and leaving lingering poison clouds. |
0 | |
The Common Cold | 5.100.103 | Poison damage | Adds a chance to shoot poison tears, dealing damage over time when inflicted. | 1 | |
The Compass | 5.100.21 | The end is near | Reveals the locations and types of all special rooms on the map, except Secret Rooms and Super Secret Rooms. | 2 | |
The Halo | 5.100.101 | All stats up | Grants one full Red Heart container, +0.3 damage, +0.2 tears, +0.25 range, +0.3 speed, and +0.5 tear falling speed. Grants one full Red Heart container, +0.3 damage, +0.2 tears, +1.5 range, and +0.3 speed. Heals 1 additional Red Heart. |
2 | |
The Inner Eye | 5.100.2 | Triple shot | Isaac shoots three tears at once with lower fire rate. | 2 | |
The Ladder | 5.100.60 | Building bridges | Allows Isaac to walk across gaps one square across by automatically placing a ladder between the two walkable sections. | 1 | |
The Ludovico Technique | 5.100.329 | Controlled tears | Instead of firing tears, Isaac controls one floating tear that hover over obstacles. This tear deals constant damage when held in place over an enemy. | 2 | |
The Mark | 5.100.79 | DMG + speed up | Grants one Soul Heart, +1 damage, and +0.2 speed. Grants one Black Heart, +1 damage, and +0.2 speed. |
3 | |
The Mind | 5.100.333 | I know all | Reveals the entire map, including all special rooms and Secret Rooms. | 3 | |
The Mulligan | 5.100.151 | They grow inside | Tears have a 1/6 chance of spawning allied Blue Flies when they hit an enemy. | 3 | |
The Pact | 5.100.80 | DMG + tears up | Grants two Soul Hearts, +0.5 damage, and +0.7 tears. Grants two Black Hearts, +0.5 damage, and +0.7 tears. |
3 | |
The Parasite | 5.100.104 | Split shot | Isaac's tears split in two when they hit something. | 3 | |
The Peeper | 5.100.155 | Plop! | Spawns a familiar that slowly floats around the room in a zig-zag pattern, damaging enemies it passes through. Increases the damage of tears from Isaac's left eye by 35%. | 2 | |
The Relic | 5.100.98 | Soul generator | Spawns a cross familiar that drops a Soul Heart after clearing enough rooms. | 3 | |
The Sad Onion | 5.100.1 | Tears up | +0.7 tears. | 3 | |
The Small Rock | 5.100.90 | DMG up + speed down | +1 damage, +0.2 tears, -0.2 speed. | 3 | |
The Soul | 5.100.335 | I am all | Grants two Soul Hearts. Isaac gains a pulsing aura that repels enemies and projectiles. | 3 | |
The Virus | 5.100.13 | Poison touch + speed up | Isaac poisons enemies on contact. -0.1 speed. +0.2 speed. Poisoned enemies have a chance to drop a black heart when killed. | 2 | |
The Wafer | 5.100.108 | Damage resistance | Most sources of damage that would cause more than one-half heart of damage are reduced to one-half heart instead. | 4 | |
There's Options | 5.100.249 | More options | Two items appear after defeating a Boss. Only one can be taken; the other will disappear. | 3 | |
Thunder Thighs | 5.100.314 | HP up + speed down + you feel stompy | Destroys rocks upon contact with Isaac. Adds one Red Heart container and lowers Speed. | 1 | |
Tiny Planet | 5.100.233 | Orbiting tears + range up | Massively increases Range and grants spectral tears. Tears orbit around Isaac at a fixed distance until they hit the ground. | 0 | |
Tooth Picks | 5.100.183 | Tears + shot speed up | +0.7 tears, +0.16 shot speed. | 3 | |
Torn Photo | 5.100.341 | Tears + shot speed up | +0.7 tears, +0.16 shot speed. | 3 | |
Tough Love | 5.100.150 | Tooth shot | Adds a chance to shoot a tooth instead of a tear, which deals x3.2 Isaac's damage. | 3 | |
Transcendence | 5.100.20 | We all float down here... | Grants flight. | 3 | |
Treasure Map | 5.100.54 | Full visible map | Reveals the map of each floor. It does not identify special rooms and does not reveal the locations of Secret Rooms / Super Secret Rooms. | 2 | |
Trinity Shield | 5.100.243 | You feel guarded | Isaac gains a shield that protects him from enemy shots. It aims in the direction Isaac fires from. | 2 | |
Virgo | 5.100.303 | You feel refreshed and protected | Adds a chance to give a shield that nullifies all incoming damage for 10 seconds upon taking damage. Also converts bad pills into good pills. | 2 | |
Whore of Babylon | 5.100.122 | Curse up | Grants +1.5 Damage and +0.3 Speed whenever Isaac has a Half Red Heart or less. | 2 | |
Wire Coat Hanger | 5.100.32 | Tears up | +0.7 tears. | 3 | |
Wooden Spoon | 5.100.27 | Speed up | +0.3 speed. | 1 | |
X-Ray Vision | 5.100.76 | I've seen everything | Reveals and opens all Secret Room and Super Secret Room entrances. | 2 | |
8 Inch Nails | 5.100.359 | Stick it to 'em! | +1.5 damage. Replaces Isaac's tears with nails, which have increased knockback. | 3 | |
Athame | 5.100.408 | Call to the void | When Isaac takes damage, a damaging black ring briefly appears around him. This ring can cause enemies to drop Black Hearts. After Isaac kills an enemy, adds a luck-based chance to spawn a damaging black ring around them. |
3 | |
Betrayal | 5.100.391 | Turn your enemy | Charms all enemies in the room when Isaac takes damage. Enemies are able to damage each other. If an enemy is damaged by another enemy, they will attack that enemy instead of Isaac. |
1 | |
Binky | 5.100.438 | Tears up | Grants one Soul Heart, +0.75 tears and decreases Isaac's size. | 3 | |
Black Powder | 5.100.420 | Spin the black circle! | Isaac leaves a trail of black powder on the floor. Walking in a circle will spawn a pentagram symbol on the floor, which deals 10 damage per tick to any enemies inside it. | 1 | |
Bomber Boy | 5.100.353 | Cross blast + 5 bombs | +5 Bombs. Isaac's bombs will now explode in a large cross-shaped pattern (roughly 5 bombs explosions wide). This also affects player-spawned Troll Bombs. | 2 | |
Bumbo | 5.100.385 | Bumbo want coin! | Spawns a beggar familiar which picks up any nearby coins, leveling up after collecting several coins. At level 2, Bumbo gains a body. At level 3, it begins to fire tears. At level 4, Bumbo follows enemies and gains contact damage. | 1 | |
Bursting Sack | 5.100.377 | Spider love | Spider enemies no longer target or deal contact damage to Isaac. | 1 | |
Cambion Conception | 5.100.412 | Feed them hate | After taking damage a certain amount of times, a permanent demonic familiar spawns. | 2 | |
Car Battery | 5.100.356 | Active power up | Causes Isaac's activated item to activate twice on each use. | 3 | |
Censer | 5.100.387 | Peace be with you | Spawns a familiar which creates a circular aura that slows down enemies and enemy shots inside. | 3 | |
Chaos | 5.100.402 | !!! | Drops 1-6 random pickups on the floor. Causes items to be chosen from random item pools. | 3 | |
Charged Baby | 5.100.372 | Bbbzzzzzt! | Spawns a familiar that occasionally drops a Lil' Battery, gives an active item charge, or petrifies all enemies in the room. | 3 | |
Circle of Protection | 5.100.423 | Protect me from myself | Surrounds Isaac with a large white halo that occasionally deals Isaac's tear damage to enemies inside it, and can convert enemy shots into friendly homing tears. | 2 | |
Continuum | 5.100.369 | Transcendent tears | Grants spectral tears and increases range. Tears travel through walls and appear at the opposite side of the room. | 2 | |
Crown Of Light | 5.100.415 | The untainted gain power | +2 Soul Hearts. While Isaac has no empty red hearts, grants 2x damage, -0.3 shot speed, and increased range. Regardless of health, the crown deactivates for the current room when Isaac takes damage. | 4 | |
Curse of the Tower | 5.100.371 | Embrace chaos | Upon taking damage, spawns six Troll Bombs around the room, similar to the effect of XVI - The Tower. | 0 | |
Dead Eye | 5.100.373 | Accuracy brings power! | Isaac's damage increases each time an enemy is hit. Damage is reset upon missing a shot. | 3 | |
Deep Pockets | 5.100.416 | More money! | Allows Isaac to carry two cards or pills (or a combination of both) at the same time. Increases the coin cap to 999. If a room would otherwise yield no reward, 1-3 coins will spawn. |
2 | |
Eden's Blessing | 5.100.381 | Tears up + your future shines brighter | +0.7 tears up. Grants a random item at the start of the next run. | 3 | |
Empty Vessel | 5.100.409 | I reward an empty vessel | Grants two Black Hearts. While Isaac has no red hearts, grants flight and periodically grants an invincibility shield for a few seconds. | 2 | |
Epiphora | 5.100.368 | Intensifying tears | Shooting in one direction increases Isaac's rate of fire until the cap is reached. As soon as Isaac changes direction or stops shooting, rate of fire is reset to its normal amount. | 2 | |
Evil Eye | 5.100.410 | Eye shot! | Adds a chance to fire a slow-moving eye that fires tears in the same direction as Isaac. The eye is destroyed when it hits an enemy or obstacle. | 2 | |
Explosivo | 5.100.401 | Sticky bomb shot! | Isaac's tears have a chance to stick to enemies and explode. | 3 | |
Farting Baby | 5.100.404 | He farts! | Spawns a familiar that follows Isaac and blocks enemy shots. If a shot hits Farting Baby, it has a chance to fart, which charms, poisons, or knocks back nearby enemies. | 1 | |
Fate's Reward | 5.100.361 | Your fate beside you | A blue head familiar that will follow Isaac and fire tears copying his tear effects and damage. | 2 | |
Friend Zone | 5.100.364 | Friendly fly | Spawns a white attack fly that orbits somewhere between Distant Admiration and Forever alone, dealing 45 damage per second. | 1 | |
Fruit Cake | 5.100.418 | Rainbow effects! | Isaac's tears gain a random effect that changes every shot. | 2 | |
GB Bug | 5.100.405 | Double tap glitch | Spawns a familiar that bounces diagonally around the room, applying a random status effect to enemies it hits and has a chance to re-roll pickups it passes over. Spawns a familiar that follows Isaac. Double tapping the fire button launches it forward, causing it to reroll the first monster or pickup it hits. |
1 | |
Glitter Bombs | 5.100.432 | Prize bombs! | +5 Bombs. Bombs have a chance to drop random pickups or charm enemies when they explode. | 2 | |
God's Flesh | 5.100.398 | Shrink shot! | Tears have a chance to shrink enemies, making them run away from Isaac. Shrunk enemies can be crushed and killed by walking over them. | 1 | |
Head of the Keeper | 5.100.429 | Penny tears! | Isaac's tears become coins and now have a chance to drop Pennies on the floor upon successfully hitting an enemy. | 2 | |
Holy Light | 5.100.374 | Holy death shot | Adds a chance to fire holy tears, which will create a damaging light beam in the area if they hit an enemy. | 3 | |
Host Hat | 5.100.375 | Blast resistance | A host familiar that sits on Isaac's head and has a random chance to block enemy shots and retaliate with 3 tears. Grants immunity to explosions. | 3 | |
Immaculate Conception | 5.100.413 | Feed them love | Upon picking up a certain amount of health, spawn a permanent angelic familiar. | 1 | |
Incubus | 5.100.360 | Dark friend | Spawns a demonic familiar that shoots tears identical to Isaac's in terms of damage, tears, and tear effects. | 4 | |
Key Bum | 5.100.388 | He wants your keys! | Spawns a familiar that follows Isaac and collects Keys for himself, giving random Chests in return. | 0 | |
Kidney Stone | 5.100.440 | Matt's kidney stone | Isaac is occasionally forced to stop firing and charge an attack that launches a massive piercing, spectral kidney stone and a barrage of tears. -0.2 speed, decreases range. | 2 | |
Lil Chest | 5.100.362 | What's in the box? | Spawns a chest familiar that spawns a random pickup (25% chance) or trinket (10% chance) upon clearing a room. | 2 | |
Lil Gurdy | 5.100.384 | A gurd of your own! | A Gurdy Jr. familiar that charges up while Isaac is firing, bouncing around the room when released and dealing contact damage based on its speed. | 2 | |
Lil Loki | 5.100.435 | 4-way buddy! | Spawns a Loki familiar that follows Isaac and fires 4 tears in a cross pattern. | 1 | |
Lost Fly | 5.100.365 | Lost protector | Spawns a fly familiar that moves in a straight line and circles around the first wall or obstacle it hits. It deals 105 damage per second on contact. It deals 56 damage per second and forces nearby enemies to attack it. | 2 | |
Lusty Blood | 5.100.411 | Their blood brings rage! | Isaac's damage increases for the current room each time he kills an enemy. | 3 | |
Marked | 5.100.394 | Directed tears | Isaac will automatically fire tears directed at a red target on the ground. The target can be moved with tear controls. +0.7 tears, increases range. | 1 | |
Maw Of The Void | 5.100.399 | Consume thy enemy! | Charged by firing for 2.5 seconds and when released, creates a black ring around Isaac that rapidly deals damage. +1 damage, the ring can cause enemies to drop Black Hearts. | 3 | |
Milk! | 5.100.436 | Don't cry over it... | Spawns a glass familiar that spills on the floor upon taking damage. After the milk spills, Isaac's tear delay is decreased by 2 for the current room. After the milk spills, Isaac's fire rate is increased by 1 for the current room. | 1 | |
Mom's Pearls | 5.100.355 | Range + luck up | +1.25 range, +0.5 tear falling speed, +1 luck. +2.5 range, +1 luck. Grants one Soul Heart. |
2 | |
More Options | 5.100.414 | There's options | Two item pedestals are presented in every Treasure Room. Only one can be taken; the other will disappear. | 3 | |
Mr. Dolly | 5.100.370 | Range + tears up | +0.7 tears, +5.25 range, +0.5 tear falling speed, Spawns a combination of 3 Red Hearts, Soul Hearts or Black Hearts on the floor when picked up. +0.7 tears, +2.5 range, spawns 3 random types of Hearts on the floor when picked up. |
3 | |
Multidimensional Baby | 5.100.431 | ydduB Buddy | Spawns a familiar that will follow Isaac's movements on a 2.5-second delay. Tears that pass through the baby will be doubled and increase in speed. | 2 | |
My Shadow | 5.100.433 | Me! And my shaaaadow! | Inflicts fear on all enemies in the room upon taking damage and spawns black friendly Chargers that attack enemies. Spawns a shadow familiar that closely follows behind Isaac. It spawns a black friendly Charger whenever an enemy touches it. |
2 | |
Night Light | 5.100.425 | Scared of the dark? | A cone of light shines in the direction Isaac is moving that slows enemies and enemy shots. | 1 | |
Number Two | 5.100.378 | Uh oh... | Continuously firing tears for three seconds causes Isaac to drop a Butt Bomb, which damages and confuses all enemies in the room when it explodes. | 2 | |
Obsessed Fan | 5.100.426 | Follows my every move... | Spawns a familiar that follows Isaac's movements on a delay and deals 30 contact damage per second to enemies. | 0 | |
Papa Fly | 5.100.430 | Turret follower | Spawns a familiar that follows Isaac's movements on a 3 second delay, firing tears at nearby enemies. | 1 | |
Pay To Play | 5.100.380 | Money talks | +5 Coins. Most doors require one Penny to open instead of a Key. +5 Coins. All locked doors, Locked Chests, and Key Blocks must be opened with one Penny instead of Keys. |
2 | |
Pupula Duplex | 5.100.379 | Wide shot | Gives Isaac spectral tears and gives his tears a wide arc shape, increasing their size. | 2 | |
Purity | 5.100.407 | Aura stat boost | Boosts one of Isaac's stats depending on the color of the aura around him. The aura disappears upon taking damage and reappears with a random color upon entering a new room. Red boosts damage, blue boosts tears, yellow boosts speed, and orange boosts range. | 3 | |
Restock | 5.100.376 | Never ending stores! | Causes Shops to instantly restock their items when they are bought. Outside of Greed Mode, the restocked item's cost is increased after each purchase. | 2 | |
Rune Bag | 5.100.389 | Rune generator | Spawns a familiar that drops a random rune after clearing enough rooms. | 3 | |
Sack Head | 5.100.424 | More sacks! | Spawns a Grab Bag on pickup. Coins, Bombs, Keys, cards, runes and batteries have a chance to become Grab Bags. | 3 | |
Scatter Bombs | 5.100.366 | We put bombs in your bombs! | +5 Bombs. Isaac's bombs explode into 2-4 tiny bombs. | 1 | |
Seraphim | 5.100.390 | Sworn friend | Spawns an angel familiar who follows Isaac and fires homing tears which deal 10 damage and have 75% shot speed. | 3 | |
Serpent's Kiss | 5.100.393 | The kiss of death | Tears have a chance to apply a poison effect to enemies. Isaac poisons enemies on contact. Poisoned enemies have a chance to drop a Black Heart when killed. | 2 | |
Spear Of Destiny | 5.100.400 | Your destiny | In addition to tears, Isaac holds a spear in front of him which deals contact damage equal to 2× his tear damage, and occasionally inflicts fear. | 2 | |
Spider Mod | 5.100.403 | Mod buddy! | Displays Isaac's tear damage and enemy health bars. Spawns a familiar that wanders around and inflicts random status effects on enemies it touches. Can spawn a Lil' Battery/Blue spider upon clearing a room. | 1 | |
Sticky Bombs | 5.100.367 | Egg sack bombs! | +5 Bombs. Bombs stick to enemies and spawn 2-4 Blue Spiders if they kill an enemy. They also leave a long-lasting puddle of slowing white creep. | 2 | |
Succubus | 5.100.417 | Damage booster | Spawns a flying familiar that bounces around the room with a black aura, dealing rapid damage to any enemies inside it. While standing in the aura, Isaac gains a 1.5× tear damage multiplier. | 3 | |
Sworn Protector | 5.100.363 | Protective friend | Spawns an orbital familiar which does 105 damage per second and attracts and blocks enemy shots. Upon blocking 10 shots in a room, it drops an Eternal Heart. | 3 | |
Tech X | 5.100.395 | Laser ring tears | Tears are replaced with laser rings that pierce through enemies and deal damage to enemies within them. Can be charged to increase the effectiveness of the ring. | 4 | |
The Wiz | 5.100.358 | Double wiz shot! | Grants spectral tears. Tears simultaneously fire out of both eyes diagonally, similar to the effect of the R U a Wizard? pill. | 0 | |
Toxic Shock | 5.100.350 | Mass poison | Upon entering a room, poisons all enemies, dealing double Isaac's tear damage. Killing enemies leaves a small, short-lasting pool of green creep on the ground. | 3 | |
Tractor Beam | 5.100.397 | Controlled tears | Isaac's tears are bound to a beam emitting in the direction he's firing. +0.5 Tears, +5.25 Range, +0.16 Shot Speed. +1 Fire Rate, +2.5 Range, +0.16 Shot Speed. | 3 | |
Zodiac | 5.100.392 | The heavens will change you | Gives Isaac a random zodiac item effect that changes every floor. | 1 | |
7 Seals | 5.100.526 | Lil harbingers! | Spawns a random Harbinger familiar that changes every 10 seconds. Harbingers have different behaviors and spawn themed Locusts. | 2 | |
Acid Baby | 5.100.491 | Pills pills pills! | Spawns a familiar that drops a random pill every 3 rooms. Upon using a pill, all enemies in the room are poisoned. | 2 | |
Adrenaline | 5.100.493 | Panic = power | Increases damage based on how many empty Red Heart containers Isaac has. | 2 | |
Analog Stick | 5.100.465 | 360 tears! | +0.35 tears up. Allows Isaac to fire tears diagonally. | 2 | |
Angelic Prism | 5.100.528 | Eclipsed by the moon | Spawns an orbital familiar with a large orbital radius. Tears that pass through the prism split into four multi-colored tears. | 3 | |
Angry Fly | 5.100.511 | He's violent | Spawns a fly familiar that orbits around a random enemy and deals 30 damage per second to enemies it comes in contact with. | 1 | |
Apple! | 5.100.443 | Trick or treat? | +0.3 tears. Adds a chance to fire a razor blade that deals 4× Isaac's damage. | 3 | |
Backstabber | 5.100.506 | Watch your back! | Isaac's tears deal double damage and inflict bleeding on enemies if they're facing away from Isaac. | 3 | |
Belly Button | 5.100.458 | What's in there? | Drops a random trinket. Grants a second trinket slot. | 2 | |
Big Chubby | 5.100.473 | Chub chub | Spawns a familiar that follows Isaac and charges across the room when Isaac fires, blocking shots and dealing 40.5 damage per second on contact. | 1 | |
Blanket | 5.100.535 | You feel Safe | Grants one Soul Heart. Upon entering a boss room, grants a shield that blocks one hit, then disappears. | 2 | |
Bloodshot Eye | 5.100.509 | Bloody friend | Spawns an orbital familiar that deals 30 damage per second and fires a randomly angled tear every 2 seconds. | 1 | |
Bozo | 5.100.513 | Party time! | +0.1 flat damage, grants a Soul Heart. Enemies can randomly become briefly charmed or feared. Taking damage has a chance to spawn a Rainbow Poop. | 2 | |
Broken Modem | 5.100.514 | Lag! | Enemies, enemy shots, tears, and pickups will briefly freeze in place at random intervals. The reward from clearing a room will sometimes be duplicated. | 3 | |
Buddy in a Box | 5.100.518 | What could it be?! | Spawns a familiar with a random tear effect. The familiar is randomized at the start of each floor. | 2 | |
Camo Undies | 5.100.497 | Camo kid | Isaac becomes camouflaged at the beginning of each room. Until he shoots, all non-boss enemies will be confused. Isaac gains +0.5 Speed while camouflaged, and gains Tears and Damage upon breaking it. | 3 | |
Compound Fracture | 5.100.453 | Bone tears! | Increases Range. Tears turn into bones, which shatter into 1-3 bone shards upon hitting an enemy or obstacle. | 3 | |
Cone Head | 5.100.457 | Hard headed! | Grants a Soul Heart. Gives Isaac a chance to ignore any damage taken. | 2 | |
Contagion | 5.100.466 | Outbreak! | The first enemy killed in a room releases a gas cloud that poisons nearby enemies. Affected enemies will also release gas upon death, spreading the effect. | 2 | |
Dad's Lost Coin | 5.100.455 | I remember this... | +1.5 range, +1 tear falling speed. Drops a Lucky Penny. +2.5 range. Drops a Lucky Penny. |
1 | |
Dad's Ring | 5.100.546 | Father's blessing | Creates a ring of light around Isaac that petrifies enemies in contact. | 3 | |
Dark Prince's Crown | 5.100.442 | Loss is power | When at exactly one Red Heart, +0.75 tears, +1.5 range, and +0.2 shot speed. When at exactly one Red Heart, +2 fire rate, +1.5 range, and +0.2 shot speed. |
1 | |
Dead Tooth | 5.100.446 | Toxic breath | While firing, Isaac gains a green aura that poisons nearby enemies. | 1 | |
Death's List | 5.100.530 | Just hope you're not next... | Grants a pickup or stat upgrade if all enemies in a room are killed in the order they are marked. | 2 | |
Depression | 5.100.469 | :( | Spawns a familiar that leaves a trail of creep that damages enemies at 6 damage per second. Has a chance to spawn damaging beams of light onto enemies that touch the cloud. | 1 | |
Divorce Papers | 5.100.547 | Tears up + you feel empty | Grants one Bone Heart, +0.7 tears, spawns a Mysterious Paper. | 3 | |
Dog Tooth | 5.100.445 | Bark at the moon! | +0.3 damage, +0.1 speed. Plays a howl or bark sound when entering a room with undiscovered Secret Rooms or Crawl Spaces. | 2 | |
Duality | 5.100.498 | You feel very balanced | Whenever a Devil Room or Angel Room would spawn after defeating a boss, both rooms spawn. Only one can be entered. | 1 | |
Eucharist | 5.100.499 | Peace be with you | An Angel Room will always spawn after every boss fight, excluding the first floor and floors after Chapter 4. | 3 | |
Euthanasia | 5.100.496 | Needle shot | Adds a luck-based chance to fire needles that instantly kill basic enemies and deal triple damage to bosses. If a needle kills an enemy, it bursts into more tears/needles. | 3 | |
Eye of Belial | 5.100.462 | Possessed tears! | Grants piercing tears. After piercing one enemy, tears start homing and deal double damage. | 3 | |
Eye of Greed | 5.100.450 | Gold tears! | Every 20 tears, Isaac loses 1 Penny and shoots an additional gold tear that petrifies enemies and turns them into gold. Any enemy killed while in this state will drop coins. | 2 | |
Fast Bombs | 5.100.517 | Rapid bomb drops | +7 Bombs. Removes the delay between bomb placements, allowing them to be placed rapidly. Bombs will no longer knock each other away. | 1 | |
Finger! | 5.100.467 | Watch where you point that! | Spawns a finger familiar that faces in the same direction as Isaac, rapidly damaging enemies it points at for 10% of Isaac's damage. | 1 | |
Flat Stone | 5.100.540 | Skipping tears | Tears bounce off the floor, creating splashes. Splashes deal 25% of Isaac's tear damage to all enemies in a small area. | 2 | |
Ghost Pepper | 5.100.495 | Flame tears | Gives a chance to shoot fires alongside tears that block enemy shots and deal damage to enemies that touch them. Gives a chance to shoot blue fires alongside tears that become smaller as they travel. |
3 | |
Glaucoma | 5.100.460 | Blind tears! | Adds a chance to shoot tears that confuse enemies for an extremely long time. | 1 | |
Glyph of Balance | 5.100.464 | A gift from above | Grants 2 Soul Hearts and modifies drops from Champion monsters based on certain conditions. Also modifies room clear drops. | 2 | |
Greed's Gullet | 5.100.501 | Money = health! | Grants a Red Heart container for every 25 Coins Isaac has. | 1 | |
Haemolacria | 5.100.531 | I'm seeing red... | Turns Isaac's tears into large blood tears fired in an arc. Upon hitting the floor, an obstacle, or an enemy, they burst into many smaller tears in all directions. Increases tear delay. | 4 | |
Hallowed Ground | 5.100.543 | Portable sanctuary | Spawns a white poop familiar, which turns into a White Poop when Isaac is hurt. White poop has an aura that increases tear fire rate and can block enemy shots. The aura also increases damage by 20% and gives homing. | 1 | |
Hushy | 5.100.470 | Lil hush! | Spawns a Hush familiar that bounces diagonally around the room and deals contact damage. While firing tears, it stops moving. | 0 | |
Jacob's Ladder | 5.100.494 | Electric tears | Tears fire sparks of electricity in random directions upon hitting an obstacle or enemy. | 3 | |
Jaw Bone | 5.100.548 | Fetch! | Spawns a familiar that flies through the room while firing, dealing a flat 7 contact damage to enemies and retrieving pickups. | 1 | |
Jumper Cables | 5.100.520 | Bloody recharge | Grants an active item charge every 15 enemies killed. | 3 | |
King Baby | 5.100.472 | Hail to the king baby | Spawns a familiar that follows Isaac and makes other familiars follow it. While firing tears, other familiars stop moving. | 1 | |
Lachryphagy | 5.100.532 | Feed them! | Isaac's tears decelerate as they travel. Upon stopping or hitting an obstacle, they burst into 8 tears in all directions. Tears can be fired into other tears to feed them, increasing their damage. | 2 | |
Large Zit | 5.100.502 | Creep shots | Adds a chance to fire a creep shot that deals double damage and leaves a trail of slowing white creep. | 1 | |
Lead Pencil | 5.100.444 | He's a bleeder! | After every 15 tears fired, Isaac will fire a high-damage cluster of tears. | 3 | |
Leprosy | 5.100.525 | You're tearing me apart! | Upon taking damage, grants a body part as an orbital, which blocks enemy shots and deals 7 damage per tick to enemies it comes in contact with. The orbitals will be destroyed if they take enough damage from enemies or enemy shots. | 1 | |
Lil Delirium | 5.100.519 | Delirious friend | Grants a familiar that transforms into another random familiar every 10 seconds. | 2 | |
Lil Monstro | 5.100.471 | Ain't he cute? | Spawns a familiar that fires clusters of tears. Must be charged before shooting. | 2 | |
Lil Spewer | 5.100.537 | Puking buddy | Drops a random pill, and spawns a familiar that charges up and fires creep. Using pills changes the creep type. | 1 | |
Linger Bean | 5.100.447 | Crying makes me toot | Constantly shooting causes Isaac to release gas clouds that can be pushed by his tears and damage nearby enemies. | 0 | |
Little Horn | 5.100.503 | Big brother is watching | Adds a chance to fire a piercing tear that instantly kills any enemy that it touches. Adds a chance to fire a tear that summons Big Horn's hand to crush the first enemy it hits, instantly killing monsters or greatly damaging bosses. |
3 | |
Marbles | 5.100.538 | Choking hazard | Spawns 3 random trinkets. Taking damage has a 5% chance to swallow Isaac's currently held trinket, gaining its effect permanently. | 2 | |
Metal Plate | 5.100.449 | It itches... | Grants one Soul Heart. Enemy shots have a chance to be reflected at the shooter as confusing tears. | 1 | |
Mom's Razor | 5.100.508 | It's sharp! | Spawns an orbiting razor that deals contact damage and inflicts bleeding on enemies, causing them to slowly take damage over time. | 2 | |
Mystery Egg | 5.100.539 | Sacrificial insemination | Spawns an egg familiar, which hatches a random friendly monster when Isaac is hurt once per room. The power of the monster improves for each consecutive room cleared without taking damage. | 1 | |
Parasitoid | 5.100.461 | Egg tears! | Adds a chance to fire an egg sack which creates slowing creep and spawns a Blue Fly or Blue Spider upon hitting an enemy. | 3 | |
Pointy Rib | 5.100.544 | Stabbing time | Spawns a bone familiar that hovers back and forth in front of Isaac, dealing damage equal to Isaac's damage. | 2 | |
Polydactyly | 5.100.454 | Hold me! | Allows Isaac to carry two cards, pills, or any combination of both. Spawns one random card, rune, or pill. | 2 | |
Pop! | 5.100.529 | Eyeball tears! | Replaces Isaac's tears with eyeballs that can bounce off of each other. The eyeballs are not limited by range, and will instead dissipate when they stop moving or when hitting an enemy or obstacle. | 1 | |
Sack of Sacks | 5.100.500 | Gives sacks | Spawns a familiar that drops a Grab Bag every few rooms cleared. | 3 | |
Schoolbag | 5.100.534 | Extra active item room | Allows Isaac to hold two active items. | 3 | |
Shade | 5.100.468 | It follows | Spawns a shadow familiar that follows Isaac's movements on a 1 second delay and deals contact damage to enemies. After dealing enough damage, it is absorbed by Isaac and spawns friendly Chargers. | 0 | |
Shard of Glass | 5.100.448 | Blood and guts! | Upon taking damage, Isaac has a chance to drop a full red heart, gain 5 range, and leave a trail of damaging red creep for the current room. Taking damage causes Isaac to bleed, spraying a volley of blood in the direction he fires. Bleeding will eventually damage him, but it can be stopped by picking up a Red Heart. |
1 | |
Sinus Infection | 5.100.459 | Booger tears! | Adds a chance to fire a booger that sticks to enemies and deals damage over time. | 3 | |
Slipped Rib | 5.100.542 | Projectile shield | Spawns a bone familiar that circles around Isaac and reflects enemy shots. | 2 | |
Sulfuric Acid | 5.100.463 | Acid tears! | +0.3 damage. Adds a chance to fire acidic tears which can destroy obstacles and open doors. | 2 | |
Tarot Cloth | 5.100.451 | I see the future | Drops a random card or rune. Doubles the effects of most cards and runes. Doubles the effects of tarot cards. | 2 | |
Technology Zero | 5.100.524 | Static tears! | Connects Isaac's tears with electricity that can damage enemies. | 3 | |
Trisagion | 5.100.533 | Smite thy enemy | Tears are replaced with piercing white blasts of light that deal less damage but can damage the same enemy multiple times. | 3 | |
Varicose Veins | 5.100.452 | I'm leaking... | Taking damage releases a ring of 10 high damage tears. | 1 | |
YO LISTEN! | 5.100.492 | Yo listen! | +1 luck. Spawns a fairy familiar that points out Secret Rooms, Crawl Space entrances, and tinted rocks. | 2 | |
120 Volt | 5.100.559 | Zap! | Repeatedly zaps enemies that are close to Isaac. | 2 | |
2Spooky | 5.100.554 | 4me | Enemies near Isaac are afflicted with fear. | 1 | |
4.5 Volt | 5.100.647 | Beat the juice out of them! | Active items don't charge when clearing rooms. Instead, they're charged by dealing damage to enemies. | 2 | |
A Bar of Soap | 5.100.564 | Tears + shot speed up | +0.5 Tears, +0.2 Shot Speed. | 3 | |
A Pound of Flesh | 5.100.672 | Blood money | Devil deals now cost Coins, Shop items now cost health, and consumables in shops are free but surrounded by spikes. | 1 | |
Act of Contrition | 5.100.601 | Tears up, you feel forgiven | +0.7 tears, grants an Eternal Heart. Allows Angel Rooms to appear even if a Devil Deal has been taken before. Reduces the Devil/Angel room chance penalty for taking Red heart damage. | 3 | |
Akeldama | 5.100.641 | Spill your guts | While in an uncleared room, Isaac forms a trail of bloody tears that drags behind him, bursting and dealing damage upon contact with enemies. | 2 | |
Almond Milk | 5.100.561 | DMG down + tears up + you feel nutty | Quadruples fire rate, with ×0.3 damage multiplier. Each tear is given a random effect that alters its movement. | 1 | |
Astral Projection | 5.100.677 | The true out-of-body experience! | Causes Isaac to turn into a ghost if he gets hit while in an uncleared room, giving him flight and spectral tears and blocking the next hit he takes. | 2 | |
Azazel's Rage | 5.100.699 | Ancient power | Isaac builds rage every time a room is cleared. After four rooms, fires a large Brimstone laser when entering the next room. | 2 | |
Belly Jelly | 5.100.690 | Bounce away! | Causes enemies to bounce off of Isaac, dealing damage to them if they hit an enemy or obstacle. Also gives Isaac the chance to deflect enemy shots. | 3 | |
Bird Cage | 5.100.610 | Fat buddy | The first time Isaac takes damage in a room, a familiar leaps on an enemy, dealing damage and releasing a rock wave. For the rest of the room, it chases enemies similar to Dead Bird. | 1 | |
Birthright | 5.100.619 | ??? | Grants a character-specific effect that enhances their special abilities. | 3 | |
Blood Bombs | 5.100.614 | Bloody blast + HP up | Grants a Red Heart container and restores 5 hearts. Bombs leave behind damaging red creep. Isaac can place Bombs at the cost of half a heart if he doesn't have any. | 2 | |
Blood Oath | 5.100.569 | Bleed me dry | Stabs Isaac at the beginning of each floor, draining his Red Hearts. Increases damage and speed for the floor based on the amount drained. | 1 | |
Bloody Gust | 5.100.695 | May your rage bring haste | The first 6 times Isaac takes damage on a given floor, he gains Speed and Fire Rate for the rest of the floor, up to a maximum of +1.02 and +3.00, respectively. | 2 | |
Boiled Baby | 5.100.607 | Messy friend | Gives Isaac a familiar that fires chaotic bursts of tears in all directions. | 1 | |
Bone Spurs | 5.100.683 | Break your enemies | Enemies spawn floating bones on death, which block shots and damage/repel enemies that touch them. | 2 | |
Bot Fly | 5.100.629 | Defense drone | Spawns an orbiting fly familiar that fires shielded tears at incoming enemy projectiles. | 3 | |
Brimstone Bombs | 5.100.646 | Demon blast +5 bombs | +5 Bombs. Bombs fire four Brimstone lasers in the cardinal directions upon exploding. | 2 | |
C Section | 5.100.678 | Fetus shots | Replaces tears with fetuses that chase down enemies and deal contact damage. Each shot requires a brief charge up. | 4 | |
Candy Heart | 5.100.671 | Power of love | Gives Isaac a permanent stat boost whenever he heals with Red Heart pickups. | 1 | |
Card Reading | 5.100.660 | A link to your future | Spawns two portals at the beginning of each floor that each lead to either the Boss Room, Treasure Room, or Secret Room. | 3 | |
Cracked Orb | 5.100.675 | Shards of knowledge | Unlocks doors and reveals a random room on the map when Isaac takes damage. | 1 | |
Dirty Mind | 5.100.576 | Filthy friends | Destroying poop spawns Dip Familiars that follow Isaac and damage enemies. Destroying different types of poop spawns different Dips with special effects. | 1 | |
Dream Catcher | 5.100.566 | Sweet dreams | During the transition between floors, Isaac's nightmare shows the contents of the upcoming floor's Treasure Room, as well as the floor's boss. Grants a Half Soul Heart when entering a new floor. | 2 | |
Echo Chamber | 5.100.700 | I can see see the future future future | When Isaac uses a Card, Pill, or Rune, he also uses a copy of the previous three Cards/Pills/Runes he used after picking up Echo Chamber. | 3 | |
Empty Heart | 5.100.676 | It multiplies | If Isaac has one red heart or fewer at the beginning of a floor, he gains an empty red heart container. | 1 | |
Evil Charm | 5.100.632 | Luck up + you feel protected | +2 luck. Provides immunity to burn, confusion, fear, and poison. | 2 | |
Eye Drops | 5.100.600 | Tears up | Increases the fire rate in Isaac's left eye, causing his eyes to fire at different rates. | 3 | |
Eye of the Occult | 5.100.572 | DMG up + range up + controlled tears | +1 damage, +2 range, -0.16 shot speed. Isaac's tears can be controlled mid-flight with tear controls. | 3 | |
Eye Sore | 5.100.558 | More eyes | Causes Isaac to occasionally fire extra tears in random directions while shooting. | 1 | |
False PHD | 5.100.654 | Worse pills + evil up | Converts good pills into bad pills and identifies all pills. Bad pills now have secondary positive effects. Grants one Black Heart. | 2 | |
Freezer Baby | 5.100.608 | Iced iced baby | Spawns a shooting familiar that has a chance to petrify enemies, and freezes monsters upon killing them. | 2 | |
Fruity Plum | 5.100.649 | Bouncy friend | Gives Isaac a miniature Baby Plum familiar that propels itself diagonally around the room, firing tears behind itself as it travels. | 1 | |
Ghost Bombs | 5.100.727 | Spooky blast +5 bombs | +5 Bombs. Bombs become spectral and spawn ghosts that deal contact damage to enemies and explode after 10 seconds. | 2 | |
Giant Cell | 5.100.658 | Micro friends | Causes Isaac to spawn Minisaac familiars when he takes damage, which chase and shoot at nearby enemies. | 1 | |
Glitched Crown | 5.100.689 | ????? | Item pedestals cycle between 5 random items before being picked up. | 4 | |
Heartbreak | 5.100.694 | Eternal sorrow | Grants 3 broken hearts and +0.25 damage for every broken heart Isaac has. Every otherwise fatal hit will add 2 more until Isaac has nothing but broken hearts. | 3 | |
Hemoptysis | 5.100.726 | Double tap sneeze | Double-tapping a fire button causes Isaac to sneeze blood, dealing damage to enemies in front of him. Affected enemies are cursed and take more damage from Brimstone-like attacks. | 1 | |
Hungry Soul | 5.100.684 | Out for blood | Enemies have a chance to spawn ghosts on death, which chase and deal contact damage to enemies and explode after a short time. | 2 | |
Hypercoagulation | 5.100.724 | Thick blooded | After Isaac takes damage from an enemy or donates health, launches Red Hearts from Isaac that despawn after 1.5 seconds. | 2 | |
IBS | 5.100.725 | Your stomach rumbles | Causes Isaac to throw poop, create buffing creep, or drop bombs while fighting enemies. | 0 | |
Immaculate Heart | 5.100.573 | Halo of tears | Adds one Red Heart Container and fully restores health. x1.2 damage multiplier. Isaac will occasionally fire extra tears that orbit around him. | 3 | |
Isaac's Tomb | 5.100.701 | Buried memories | Spawns an Old Chest at the start of each floor. | 3 | |
It Hurts | 5.100.560 | No it doesn't... | Releases a ring of tears and increases fire rate for the current room when Isaac takes damage. | 1 | |
Jupiter | 5.100.594 | You're a gas giant! | +2 red Heart containers, -0.3 speed. Isaac builds speed while standing still, and releases poison gas clouds when he moves afterwards. | 2 | |
Keeper's Kin | 5.100.717 | Under a rock | Rocks and other Obstacles spawn blue spiders over time while in a room with enemies, and spawn two blue spiders when destroyed. | 2 | |
Keeper's Sack | 5.100.716 | Spending power | Gives range, speed, or damage when buying things from a shop. Spawns three coins and a Key on pickup. | 3 | |
Knockout Drops | 5.100.637 | They pack a punch! | Adds a chance to shoot a fist tear that has extremely high knockback and confuses enemies. | 3 | |
Lil Abaddon | 5.100.679 | Abyssal friend | Spawns a familiar that charges a miniature Maw Of The Void attack while Isaac shoots. | 2 | |
Lil Dumpy | 5.100.615 | Puffy buddy | Spawns a Dumpy familiar that pushes away nearby enemies and projectiles just before Isaac is about to be hit, then falls asleep. He can be awoken by walking to him. | 3 | |
Lil Portal | 5.100.681 | It hungers | A familiar that flies forward, consuming pickups in its path. Each one will increase its size and damage and spawn a Blue Fly. Every four pickups, it opens a portal that leads to an unexplored room. | 1 | |
Lodestone | 5.100.617 | Magnetizing tears | Gives Isaac the chance to fire tears that magnetize enemies they hit, causing them to attract nearby pickups and enemies, as well as tears/shots from all sources. | 3 | |
Lost Soul | 5.100.612 | Protect him | Creates a ghostly familiar that closely follows behind Isaac. It dies in one hit, but respawns at the start of the next floor. Each time it survives until the next floor, it rewards Isaac with Soul Hearts, Eternal Hearts, or an Item. | 2 | |
Luna | 5.100.589 | The moon's blessing shines upon you | Adds an extra Secret Room and Super Secret Room to each floor. Secret Rooms contain a beam of light that increases Fire Rate for the current floor and gives a Half Soul Heart. | 2 | |
Mars | 5.100.593 | Double tap dash | Dash by double-tapping the movement key, becoming invulnerable and damaging enemies. There's a short cooldown before Isaac can dash again. | 2 | |
Member Card | 5.100.602 | Exclusive access! | Adds a trapdoor to every Shop that leads to a second shop with a unique stock and marked-up prices. | 2 | |
Mercurius | 5.100.590 | Speed up + you feel elusive | +0.4 speed. Doors stay open after entering a room, even in rooms with enemies. | 3 | |
Monstrance | 5.100.574 | Purifying light | Isaac gains an aura that deals damage to enemies inside it. | 2 | |
Montezuma's Revenge | 5.100.680 | Oh no... | While firing, Isaac charges up a short-ranged Brimstone-like diarrhea beam that shoots behind him. | 2 | |
Nancy Bombs | 5.100.563 | Random blast +5 bombs | +5 Bombs. Each bomb gains 1-4 random bomb synergies. | 2 | |
Neptunus | 5.100.597 | Open the floodgates | Isaac's mouth fills with tears over time while not firing, up to a cap. Holding the fire button will release all stored tears in rapid succession. | 3 | |
Ocular Rift | 5.100.606 | Stare into the abyss | Adds a chance to fire tears that create rifts where they land, which suck enemies, pickups, and shots towards them and damage enemies in the area. | 3 | |
Options? | 5.100.670 | There might be options | If a room gives a reward when cleared, there will be two different rewards to chose from. Taking one causes the other to disappear. | 2 | |
Orphan Socks | 5.100.571 | Speed up + your feet feel stronger | Prevents creep and floor spikes from damaging Isaac. Also gives Isaac +0.3 speed and 2 Soul Hearts. | 2 | |
Paschal Candle | 5.100.567 | Keep the flame burning | Gives Isaac a familiar that grants +0.4 Fire Rate for each consecutive room he's cleared without taking damage. The bonus stacks up to five times. | 3 | |
Playdough Cookie | 5.100.570 | Tasty rainbow | Grants multicolored tears. Each color comes with a different status or tear effect. | 2 | |
Pluto | 5.100.598 | Size down | +0.7 tears. Significantly shrinks Isaac, allowing him to squeeze between objects and makes some enemy shots pass over him. | 3 | |
Psy Fly | 5.100.581 | Flamboyant protector | Spawns a fly orbital familiar that chases and blocks enemy shots. | 4 | |
Quints | 5.100.661 | They lurk inside | The first five enemies killed in a room will spawn stationary shooting familiars where they died. | 2 | |
Redemption | 5.100.673 | Deliver me from evil | If Isaac enters a Devil Room but leaves without taking/opening anything in it, he gets +1 Damage and a Soul Heart at the start of the next floor. | 2 | |
Revelation | 5.100.643 | Awaken your faith | Grants flight and two Soul Hearts. In addition to tears, Isaac can charge up and fire a powerful holy laser. | 4 | |
Rock Bottom | 5.100.562 | It's only up from there | Locks Isaac's attributes to their highest values reached. | 3 | |
Rocket in a Jar | 5.100.583 | Rocket propulsion +5 bombs | +5 Bombs. If Isaac is currently firing, placing a bomb will instead shoot a fast-moving, explosive rocket in the direction he's facing. | 2 | |
Rotten Tomato | 5.100.618 | Delicious! | Adds a chance to fire tears that mark enemies with the Bait status effect. Enemies marked as bait are attacked by other enemies. | 2 | |
Sacred Orb | 5.100.691 | Destined for greatness | Prevents items of quality 0-1 from appearing, and items of quality 2 from appearing 33% of the time. Quest items are unaffected. | 4 | |
Salvation | 5.100.696 | Divine protection | Gives Isaac a halo that summons beams of light on enemies inside it. The halo grows larger the more times Isaac has taken damage this floor. | 3 | |
Sanguine Bond | 5.100.692 | He awaits your offering | Spawns a special set of spikes in the Devil Room. Taking damage from the spikes has a chance to grant a reward. | 1 | |
Saturnus | 5.100.595 | Ring of tears | Upon entering a room, a circle of tears orbits Isaac. Enemy tears have a chance to be caught in orbit, turning them friendly. | 2 | |
Sausage | 5.100.669 | All stats up | Adds a Red Heart Container, fully heals Isaac, and gives +0.2 Speed, +0.5 Damage, +0.5 Tears, +2.5 Range, +0.2 Shot Speed, and +1.0 Luck. Increases the chance of encountering a Devil Room, Angel Room, and/or Planetarium each by 6.9%. | 3 | |
Sol | 5.100.588 | Radiant victory | Reveals the location of the Boss Room. Upon defeating a boss, activates XIX - The Sun, fully recharges Isaac's active item, grants bonus damage and luck for the rest of the floor, and removes curses. | 2 | |
Soul Locket | 5.100.686 | Power of faith | Gives Isaac a permanent stat boost whenever he picks up a Soul Heart. | 1 | |
Spirit Sword | 5.100.579 | Divine blade | Instead of tears, Isaac swings a sword. Charging does a spin attack and fires a projectile, and a projectile is sometimes fired with normal swings if Isaac has no empty Red Heart Containers. | 3 | |
Stapler | 5.100.708 | DMG up | +1 Damage. Prevents Isaac from firing tears from his left eye, like Cain. | 3 | |
Star of Bethlehem | 5.100.651 | Follow the light | Spawns a star familiar that slowly travels towards the Boss Room, giving an aura that increases damage and tears and grants homing tears. | 3 | |
Terra | 5.100.592 | Born to rock | +1 Damage. Replaces tears with rocks that deal variable damage, have increased knockback, and can destroy obstacles. | 3 | |
The Intruder | 5.100.575 | Invasive friend | A familiar burrows in Isaac's head, firing 4 slowing tears. Upon taking damage, there's a chance it will burst out of Isaac's head, spawning blue spiders and chasing enemies for the current room. | 3 | |
The Swarm | 5.100.693 | Infest | Spawns eight orbital flies, which turn into Blue Flies after they block a shot. Each time a room is cleared, spawns another orbital fly. | 2 | |
Tinytoma | 5.100.645 | Itching for revenge | Gives Isaac a Teratoma orbital that blocks shots, deals contact damage, and splits into smaller versions of itself upon taking damage. The smaller versions break into blue spiders. | 1 | |
Tooth and Nail | 5.100.663 | You feel prickly | Isaac periodically turns into a spiked statue, briefly becoming invulnerable and dealing contact damage. | 2 | |
Tropicamide | 5.100.659 | Tear size + range up | +2.5 Range, Increases tear size. | 1 | |
Twisted Pair | 5.100.698 | Double trouble! | Spawns two familiars that float on either side of Isaac and fire tears that use his tears, range, shot speed, and tear effects, and scale with damage. | 4 | |
Uranus | 5.100.596 | Ice tears | Isaac shoots ice tears, which slow enemies and freeze monsters they kill. Frozen enemies slide away and explode into ice shards when touched. | 3 | |
Vasculitis | 5.100.657 | Clogged enemies | Enemies explode into tears upon death, which inherit the effects of Isaac's tears. | 1 | |
Vengeful Spirit | 5.100.702 | Hot blooded | After taking damage, spawns an orbital wisp that lasts for the entire floor, up to a maximum of six. They fire tears but do not block shots. | 1 | |
Venus | 5.100.591 | HP up + you feel pretty | Adds one red Heart container. Heals 1 additional Red Heart. Enemies near Isaac become charmed. | 2 | |
Voodoo Head | 5.100.599 | Extra curse rooms | Spawns an additional Curse Room on each floor. Curse Rooms have improved layouts. | 2 | |
Worm Friend | 5.100.682 | Clingy buddy | Gives Isaac a Nerve Ending familiar that burrows out of the ground to grab and deal damage to enemies over time. | 3 |
The Binding of Isaac: Rebirth |
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