Missing Page 2
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Missing Page 2 is a passive item.
Effects
- Grants one
Black Heart. 
Activates 
The Necronomicon effect upon taking damage if Isaac's total health ( 
Red Hearts, 
Soul Hearts, and Black Hearts) is at one heart afterward.
Deals 80 damage to everything in the room upon taking damage if Isaac's total health (Red Hearts, Soul Hearts, and Black Hearts) is at one heart afterward.- Adds +40 damage to The Necronomicon and similar effects, such as Black Hearts.
Synergies
Black Feather: Counts as an 'evil' item, granting a damage up.-
Blood Rights / 
Dry Baby / 
The Negative / 
XIII - Death: The damage boost is applied to these items. -
A Missing Page/
Missing Page 2: The damage increase from the trinket/copies of Missing Page 2 stacks, adding +40 damage per stack to The Necronomicon and similar effects.
Notes
- Works the same for
Keeper and 
Tainted Keeper and his Coin Hearts.
In-game Footage
Gallery
Missing Page 2's splash image which appears when it's activated.
Trivia
- The Necronomicon, A Missing Page, and Missing Page 2 are all references to the Necronomicon and its missing pages appearing in Evil Dead. Which, in turn, is a reference to The Necronomicon, a fictional grimoire appearing in the works of horror writer H.P. Lovecraft.
 The Binding of Isaac: Rebirth
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