Virgo
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Virgo is a passive item.
Effects
- Grants a chance to trigger the
Book of Shadows effect upon taking damage, creating a shield that nullifies all types of damage for 10 seconds.
- The activation chance depends on the luck stat and goes up to 100% with 10 Luck.
- Converts all negative pills into positive ones, but does not identify them.
Notes
- The shield negates health loss from
Blood Donation Machines and 
Devil Beggars. - Does not prevent Red Heart container loss from
Devil Room deals. - Bad pills already obtained/dropped will be converted to their "good" counterpart.
- As bad pills will turn into good pills, it is possible for two different colored pills to have the same effect.
Synergies
Celtic Cross / 
The Polaroid: Virgo can trigger at the same time as Celtic Cross or The Polaroid, cumulating to up to 22 seconds of shield.
Interactions
-
False PHD: Pills can be both good and bad again. Taking bad pills still applies the benefits from False PHD.
In-game Footage
 Zodiac Signs
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 The Binding of Isaac: Rebirth
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