Upon taking damage, spawns a white attack fly for the duration of the current room. The fly orbits Isaac at medium range, similar to Forever alone, but with much higher speed.
The fly deals 5 damage per tick (75 contact damage per second).
The fly deals 10 damage per tick (150 contact damage per second).
This item belongs to the Beelzebub set. Collecting three items from this set will transform Isaac into a giant humanoid fly.
Interactions
Best Bud: Multiple copies of Best Buds do not stack, only 1 fly can be spawned
Forever alone, but with much higher speed.
The fly deals 5 damage per tick (75 contact damage per second).
The fly deals 10 damage per tick (150 contact damage per second).
Beelzebub set. Collecting three items from this set will transform Isaac into a giant humanoid fly.
Best Bud: Multiple copies of Best Buds do not stack, only 1 fly can be spawned
Best Bud is very similar in appearance to 
Friend Zone and 
Lost Fly, making them difficult to distinguish.
Sacrificial Dagger).
Beelzebub 
The Binding of Isaac: Rebirth
