Sheol

Sheol is one of two floors following the Womb/Utero/Scarred Womb, the other being the Cathedral. After defeating Mom's Heart, depending on Isaac's deal chance, a Devil Room may spawn which will only contain a trapdoor leading down to Sheol. Other methods to enter the deal room such as Joker or Red Chests will also work. Unlocking and defeating It Lives will always spawn a trapdoor leading to Sheol, as well as a Beam of Light leading to the Cathedral. Additionally, Sheol can be accessed using We Need To Go Deeper! or Rune of Ehwaz from The Womb II.

Sheol has only one floor, featuring undead and dark/demonic enemies, and the boss is always Satan.

Monsters

Entity	ID	Description
Bony	227.0	Wanders around the room and throws a bone at Isaac when he is in sight.
Boom Fly	25.0	Flies across the room in straight diagonal lines, dealing contact damage. Explodes upon death.
Death's Head	212.0	Invulnerable enemy that moves diagonally around the room, dealing contact damage. Dies when the room is cleared.
Dip	217.0	Slowly dashes in random directions, dealing contact damage.
Squirt	220.0	Dashes towards Isaac and deals contact damage. Spawns 2 Dips upon death.
Dinga	223.0	Slowly moves around the room, occasionally hopping to spawn Dips or fire 8 Brown shots in all directions. Splits 2 Squirts upon death.
Evil Twin	53.1	Mirrors Isaac's movements and fires three spread blood shots at the same time as Isaac. Can fly over obstacles.
Bloodshot Eye	60.1	Slowly turns towards Isaac and fires a Brimstone beam at Isaac if he stands still or is too slow.
Sucker	61.0	Flies slowly towards Isaac, exploding into 4 shots in the cardinal directions upon death.
Nulls	252.0	Walks towards Isaac, dealing contact damage. Upon getting near Isaac, it will open its eyes, though its speed doesn't change. Fades into and out of visibility.
Gurgle	87.0	Walks towards Isaac, dealing contact damage and periodically firing Ipecac shots at him; they are immune to this explosion, but other enemies are not. Can turn into a Splasher upon death.
Globin	24.0	Chases Isaac, dealing a full heart of contact damage. Upon taking enough damage, it collapses into a pile of goo, which can be killed. Will regenerate after a short period of time if not killed quickly.
Gazing Globin	24.1	Quickly chases Isaac, dealing a full heart of contact damage. Upon taking enough damage, it collapses into a pile of goo, which will slide away from Isaac and can be killed. Will regenerate after a short period of time if not killed quickly.
Gurgling	237.0	Charges towards Isaac when he lines up with them, leaving a trail of Red Creep and shooting 6 blood shots.
Begotten	251.0	Starts attached to the wall or an obstacle. After a while, it detaches, firing 6 blood shots in all directions, turning the room dark, becoming invisible and chasing Isaac. Briefly becomes visible upon getting hit.
Host	27.0	Stationary enemy that is normally invulnerable. Raises its head up when Isaac gets close, revealing a fleshy stem that can be damaged. Upon raising its head, it will fire 3 blood shots in a spread and lower its head again.
Mobile Host	204.0	Acts like the Host, but follows Isaac and deals contact damage.
Selfless Knight	41.1	Moves erratically around the room and charges towards Isaac very quickly when in line of sight. Can only be damaged from behind.
Bone Knight	283.0	Moves erratically around the room, charges toward Isaac when in line of sight, and leaves behind a short-lasting trail of damaging Red Creep. Can only be damaged from behind.
Leech	55.0	Quickly charges towards Isaac when he gets in its line of sight.
Kamikaze Leech	55.1	Quickly charges towards Isaac when he gets in its line of sight. Explodes upon death.
Mr. Maw	35.0	Walks towards Isaac and attacks by launching its head towards him. Turns into a Maw or Gusher upon death depending on the killed body segment. Occasionally separates at will.
Nerve Ending	231.0	Static enemy which acts as a meat shield.
Charger	23.0	Slowly moves around the room, charging at Isaac when he gets in its line of sight.
One Tooth	234.0	Follows Isaac and periodically dashes towards him when it gets close. Deals contact damage.
Oob	224.0	When Isaac lines up with it horizontally, it charges across the room once. When Isaac is not horizontal to it, it spawns Brains.
Black Maw	225.0	When Isaac lines up with it horizontally, it charges in his direction and then doubles back, charging back to its original position. When Isaac is not horizontal to it, it spawns Leeches. Explodes when it dies.
Spider	85.0	Erratically moves around the room. If Isaac gets close to it, it chases him, trying to deal contact damage.
Big Spider	94.0	Erratically moves around the room. If Isaac gets close to it, it chases him, trying to deal contact damage. Spawns two Spiders upon death.
Ticking Spider	250.0	Crawls around the room erratically, following Isaac and dealing contact damage. Can jump small distances. Explodes upon death.
Swarmer	91.0	Slowly floats around the room, spawning several Attack Flies. Spawns Pooters upon taking damage. Spawns a Boom Fly upon death.
Camillo Jr.	230.0	Moves around the room diagonally, occasionally firing Technology lasers towards Isaac. Fires more often upon getting damaged.
Double Vis	39.1	Randomly wanders around the room. Pauses to charge and fire a Brimstone laser which fires from both sides when Isaac gets in its line of sight.
Wizoob	219.0	Disappears, then appears near Isaac and spits a cluster of spectral tears at him.
Lil' Haunt	260.0	Floats toward Isaac and occasionally fires a blood shot at him, predicting his movements.
Wall Hugger	218.0	Moves around the room like Guts, damaging Isaac by contact. Cannot be destroyed.
Brimstone Head	203.0	Stationary and invulnerable monster that fires Brimstone beams in a specific direction.
Constant Stone Shooter	202.0	Stationary and invulnerable monster that continuously fires shots in a single direction.
Gaping Maw	235.0	Stationary and invulnerable monster that sucks Isaac towards it, along with Isaac's tears and enemy projectiles.
Stone Eye	201.0	Stationary and invulnerable monster that constantly rotates and fires a flickering Technology laser. Stops firing when the room is cleared.
Imp	259.0	Slowly drifts towards Isaac, frequently firing 5 blood shots in quick succession towards him. Tries to avoid Isaac's shots and occasionally teleports and reappears elsewhere.
Dank Squirt	220.1	Dashes towards Isaac and deals contact damage, creating slowing black creep. Spawns 2 Clots upon death.
Black Bony	277.0	Wanders around the room and throws three bones in a row at Isaac when he is in sight. Explodes upon death.
Dank Death's Head	212.1	Moves diagonally around the room, dealing contact damage. Needs to be killed to complete the room.
Flesh Death's Head	286.0	Moves diagonally around the room, dealing contact damage. Releases 6 blood shots in all directions upon death. Can be killed, but also dies when the room is cleared.
Dank Globin	24.2	Chases Isaac, dealing a full heart of contact damage. Upon taking enough damage, it collapses into a pile of goo, spawns a Spider, and leaves a puddle of slowing Black Creep. Will regenerate after a short time if not killed quickly. Leaves another puddle of Black Creep upon death.
Black Globin	278.0	Chases Isaac, dealing a full heart of contact damage and launching Spiders towards Isaac whenever it takes damage. Spawns a Spider, a Black Globin's Head, and a Black Globin's Body upon death.
Black Globin's Head	279.0	Slides towards Isaac, leaving a trail of damaging Red Creep.
Black Globin's Body	280.0	Walks aimlessly around the room, occasionally spawning spiders.
Mom's Dead Hand	287.0	Falls from the ceiling. Upon landing, it spawns several rock waves that travel outwards. Spawns several spiders upon death. Entering a room containing Mom's Dead Hand will warn Isaac with Mom's laugh.
Fat Bat	258.0	Slowly flies towards Isaac. Tries to align itself diagonally to Isaac and shoots at him when in that alignment.
Scarred Double Vis	39.3	Randomly wanders around the room. Pauses to charge and fire a Brimstone laser which fires from all four cardinal sides when Isaac gets in its line of sight.
Red Ghost	285.0	Disappears, then reappears near Isaac and fires a brimstone laser.
Suction Pitfall	291.1	Invulnerable and stationary enemy which sucks Isaac towards itself. Isaac falls into it when walked over, taking damage and popping back out after a short delay.
Soul Sucker	61.2	Flies slowly towards Isaac. Spawns a vortex that fires four Brimstone beams in the cardinal directions upon death.
Mr. Red Maw	35.2	Walks towards Isaac and attacks by launching its head towards him. Turns into a Red Maw or Gusher upon death depending on the killed body segment. Occasionally separates at will.
Crispy	226.2	Slowly walks towards Isaac, but increases in speed as they take damage. Constantly passively takes damage.
Stoney	302.0	Chases Isaac and blocks tears, but does not deal contact damage. Temporarily pauses in exhaustion after a certain amount of time. Invulnerable; dies when the room is cleared.
Cross Stone Shooter	202.10	Stationary and invulnerable monster that continuously fires shots in four directions, alternating between cardinal and ordinal.
Portal	306.0	Spawns various enemies from the current floor until it either vanishes or is killed.
Wrinkly Baby	38.3	Dashes towards Isaac at high speed and fires three blood shots in his direction once stopped.
Whipper	834.0	Runs around the room, sprinting at Isaac when he gets in its line of sight and lashing at him when it gets close.
Snapper	834.1	Runs around the room, sprinting at Isaac when he gets in its line of sight and throwing out its whip when he gets in range.
Flagellant	834.2	Runs around the room. When Isaac gets in its line of sight, continuously chases him and lashes its whip, occasionally deflecting Isaac’s shots.
Shady	888.0	Walks slowly toward Isaac, occasionally firing a shot that creates shots perpendicular to itself while traveling and splits into a ring of shots upon hitting a wall or obstacle. Also occasionally jumps, creating lines of explosions in the cardinal directions. One of the few enemies that utilize Damage Scaling.
Triple Grimace	42.2	Stationary and invulnerable monster that occasionally fires a triple shot at Isaac. Stops firing when room is cleared.

Degraded Bosses:

Name	ID	Notes
The Adversary	268.0
Blastocyst	74.0
Blighted Ovum	79.2
The Cage	265.0
Dark One	267.0
Death	66.0
The Fallen	81.0
Famine	63.0
Fistula	71.0
The Gate	263.0
Gemini	79.0
Gluttony	49.0
Greed	50.0
The Haunt	260.0
Headless Horseman	82.0
The Hollow	19.1
The Husk	67.1
Larry Jr.	19.0
Little Horn	404.0
Loki	69.0
Lokii	69.1
Lust	47.0
Mega Fatty	264.0
Mega Maw	262.0
Monstro II	43.0
Peep	68.0
Pestilence	64.0
The Pile	269.1
Polycephalus	269.0
Rag Man	405.0
Rag Mega	409.0
Sloth	46.0
The Stain	401.0
Steven	79.1
Super Gluttony	49.1
Super Greed	50.1
Super Sloth	46.1
Super Wrath	48.1
Teratoma	71.1	All forms
War	65.0
Wrath	48.0
The Wretched	100.1

Boss


Satan

Gallery

Sheol concept art.

Trivia

In Hebrew, Sheol is translated as "place of the dead"; it is described as the common afterlife of humans in Jewish religious lore (including the Old Testament), making it the Abrahamic version of the underworld.
Sheol is the ninth level of the game (without there being a Curse of the Labyrinth). The 14th-century novel Inferno, the first part of Dante Aligheri's famous Divine Comedy and one of the first books to describe Hell in detail, notes that the ninth and lowest layer of Hell, where those who commit the sin of betrayal are sent, is frozen. On Isaac's last will, it says he died in "a cold place" if he dies in Sheol.
- The ninth layer of Hell is said to be where Satan, who turned against God and was cast down for it, is imprisoned, indicating the reason for Satan's presence in the area.
- It's also said that the ninth layer of Hell is the prison for Judas Iscariot, the betrayer of Jesus, which may be the reason that Judas is unlocked there.
Like in all chapters, small non-interactive objects can be found on the ground. One of these decorations is a drawing of a triangle that may be a reference to the Triforce, an iconic relic from The Legend of Zelda series.
There is an unused version of Sheol, which uses textures for Dark Room, but with a black background. It can be accessed by typing stage 10b in the Debug Console.