Angel Room (Greed Mode Item Pool)

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(except in Rebirth)

Items in this pool can be found in the Angel RoomAngel Room in Greed mode.

Activated Collectibles

Name ID Icon Weight Description
Book of Revelations 5.100.78
Book of Revelations
6 rooms
1
Increases the chance of a Devil RoomDevil Room / Angel RoomAngel Room appearing while held. Upon use, gives one Soul Heart.pngSoul Heart, and replaces the boss of the current floor with a Harbinger if possible.
(except in Rebirth and Afterbirth) Eden's Soul 5.100.490
Eden's Soul
12 rooms
1
Spawns two random items from the current room's Item Pool and then disappears. Starts with no charges.
(in Repentance and Repentance+) Breath of Life 5.100.326
Breath of Life
3 seconds
1
Grants a brief moment of invincibility when the charge bar hits zero. Isaac begins taking damage if the item is held any longer. (in Repentance and Repentance+) Isaac creates beams of light when touching enemies while invulnerable, and creates a powerful 4-way beam if blocking damage exactly as the invincibility starts.
(in Repentance and Repentance+) Genesis 5.100.622
Genesis
One time use
1
Removes all of Isaac's items and pickups and takes him to a unique Clean BedroomClean Bedroom with some pickups and Chest.pngChests and a passage to the next floor. For every item Isaac lost, he gets to take an item from a set of three.
(in Repentance and Repentance+) Jar of Wisps 5.100.685
Jar of Wisps
6 rooms
1
Spawns random wisps that shoot various tears, block shots, and deal contact damage. The number of wisps spawned increases every time the jar is used.
(in Repentance and Repentance+) Urn of Souls 5.100.640
Urn of Souls
Unlimited
1
Isaac pulls out or puts away an urn that fires a stream of damaging blue flames. It gains Soul Charges each time an enemy dies, which are used to fuel the urn.
(in Repentance and Repentance+) Vade Retro 5.100.653
Vade Retro
Unlimited
1
While held, enemies leave behind ghosts on death. Stronger enemies leave bigger ghosts. Using the item causes the ghosts to explode and damage nearby enemies, and instantly kills all ghost enemies with less than 50% HP.
(in Repentance+) The Bible 5.100.33
The Bible
4 rooms
1
Grants flight for the current room. Instantly kills Boss Mom ingame.pngMom, Boss Mom's Heart ingame.pngMom's Heart, and Boss It Lives ingame.pngIt Lives when activated, but kills Isaac when used on Boss Satan ingame.pngSatan.
(in Repentance+) Dead Sea Scrolls 5.100.124
Dead Sea Scrolls
2 rooms
1
Triggers the effect of a random activated item from a list of possible options (not every activated item is included).
(in Repentance+) Prayer Card 5.100.146
Prayer Card
6 rooms
1
Gives Isaac an Eternal Heart.pngEternal Heart.
(in Repentance+) Delirious 5.100.510
Delirious
Variable
0.4
Spawns Boss Delirium ingame.pngDelirium as a random friendly boss that fights for Isaac. (except in Repentance+) The boss lasts the for the current room. (in Repentance+) The boss persists between rooms. The charge time is based on the power of the boss summoned.

Passive Collectibles

Name ID Icon Weight Description
Blood of the Martyr 5.100.7 Blood of the Martyr
1
+1 damage. Isaac shoots blood tears.
The Body 5.100.334 The Body
1
Adds 3 Red Heart Containers.
Celtic Cross 5.100.162 Celtic Cross
1
Grants a chance to trigger the Collectible Book of Shadows icon.pngBook of Shadows effect upon taking damage, creating a shield that nullifies all types of damage for 7 seconds.
Censer 5.100.387 Censer
1
Spawns a familiar which creates a circular aura that slows down enemies and enemy shots inside.
Circle of Protection 5.100.423 Circle of Protection
1
Surrounds Isaac with a large white halo that occasionally deals Isaac's tear damage to enemies inside it, and can convert enemy shots into friendly homing tears.
Crown Of Light 5.100.415 Crown Of Light
1
+2 Soul Heart.pngSoul Hearts. While Isaac has no empty red hearts, grants 2x damage, -0.3 shot speed, (except in Repentance and Repentance+) and increased range. Regardless of health, the crown deactivates for the current room when Isaac takes damage.
Dead Dove 5.100.185 Dead Dove
1
Grants spectral tears and flight.
Godhead 5.100.331 Godhead
1
(except in Repentance and Repentance+) Grants homing tears with a damaging halo. +0.5 Damage, -0.3 Tears -0.3 Shot Speed, +0.8 Tear Falling Speed, and +1.2 Range.
(in Repentance and Repentance+) Grants homing tears with a damaging halo. +0.5 Damage, -0.3 Tears, and -0.3 Shot Speed.
Guardian Angel 5.100.112 Guardian Angel
1
Spawns an orbital familiar that blocks enemy shots, deals 7 damage per tick on contact, and increases the speed of all orbital familiars.
Holy Grail 5.100.184 Holy Grail
1
Grants flight and one Red Heart container. (in Repentance and Repentance+) Heals 1 additional Red Heart.pngRed Heart.
Holy Mantle 5.100.313 Holy Mantle
1
Grants a shield that negates the first instance of damage taken from a hostile source once per room.
Holy Water 5.100.178 Holy Water
1
(except in Repentance and Repentance+) Spawns a bottle familiar that breaks when Isaac takes damage, leaving a puddle of blue creep.
(in Repentance and Repentance+) A bottle familiar that flies forward when Isaac shoots. It breaks upon hitting an enemy, leaving a puddle of blue creep that petrifies enemies.
Immaculate Conception 5.100.413 Immaculate Conception
1
Upon picking up a certain amount of health, spawn a permanent angelic familiar.
Jesus Juice 5.100.197 Jesus Juice
1
(except in Repentance and Repentance+) +0.5 damage, +0.25 range, +0.5 tear falling speed.
(in Repentance and Repentance+) +0.5 damage, +1.5 range.
The Mind 5.100.333 The Mind
1
Reveals the entire map, including all special rooms and Secret RoomSecret Rooms.
Purity 5.100.407 Purity
1
Boosts one of Isaac's stats depending on the color of the aura around him. The aura disappears upon taking damage and reappears with a random color upon entering a new room. Red boosts damage, blue boosts tears, yellow boosts speed, and orange boosts range.
Rosary 5.100.72 Rosary
1
Grants 3 Soul Heart.pngSoul Hearts. Causes Collectible The Bible icon.pngThe Bible to appear in any item pool. (in Repentance and Repentance+) +0.5 tears.
Sacred Heart 5.100.182 Sacred Heart
1
(except in Repentance and Repentance+) Adds a Red Heart Container. Grants homing tears, a x2.3 Damage multiplier, +1 flat Damage, -0.4 Tears, -0.25 Shot Speed, and +4.125 Range.
(in Repentance and Repentance+) Adds a Red Heart Container. Grants homing tears, a x2.3 Damage multiplier, +1 flat Damage, -0.4 Tears, and -0.25 Shot Speed.
Seraphim 5.100.390 Seraphim
1
Spawns an angel familiar who follows Isaac and fires homing tears which deal 10 damage and have 75% shot speed.
The Soul 5.100.335 The Soul
1
Grants two Soul Heart.pngSoul Hearts. Isaac gains a pulsing aura that repels enemies and projectiles.
Spear Of Destiny 5.100.400 Spear Of Destiny
1
In addition to tears, Isaac holds a spear in front of him which deals contact damage equal to 2× his tear damage, and occasionally inflicts fear.
Stigmata 5.100.138 Stigmata
1
+0.3 damage, grants one full Red Heart container. (in Repentance and Repentance+) Heals 1 additional Red Heart.pngRed Heart.
Sworn Protector 5.100.363 Sworn Protector
1
Spawns an orbital familiar which does 105 damage per second and attracts and blocks enemy shots. Upon blocking 10 shots in a room, it drops an Eternal Heart.pngEternal Heart.
Trinity Shield 5.100.243 Trinity Shield
1
Isaac gains a shield that protects him from enemy shots. It aims in the direction Isaac fires from.
(except in Repentance and Repentance+) Cube of Meat 5.100.73 Cube of Meat
1
Creates an orbital familiar. Collecting additional copies gives it the ability to shoot tears, then chase enemies to deal contact damage, then deal even more contact damage.
(except in Repentance and Repentance+) Mitre 5.100.173 Mitre
1
Grants a chance of converting any Red Heart.pngRed Heart pickups that spawn into Soul Heart.pngSoul Hearts instead.
(except in Rebirth and Afterbirth) 7 Seals 5.100.526 7 Seals
1
Spawns a random Harbinger familiar that changes every 10 seconds. Harbingers have different behaviors and spawn themed Locusts.
(except in Rebirth and Afterbirth) Angelic Prism 5.100.528 Angelic Prism
1
Spawns an orbital familiar with a large orbital radius. Tears that pass through the prism split into four multi-colored tears.
(except in Rebirth and Afterbirth) Eucharist 5.100.499 Eucharist
1
An Angel RoomAngel Room will always spawn after every boss fight, excluding the first floor and floors after Chapter 4.
(except in Rebirth and Afterbirth) Trisagion 5.100.533 Trisagion
1
Tears are replaced with piercing white blasts of light that deal less damage but can damage the same enemy multiple times.
(in Afterbirth †) Glyph of Balance 5.100.464 Glyph of Balance
1
Grants 2 Soul Heart.pngSoul Hearts and modifies drops from Champion monsters based on certain conditions. (in Repentance and Repentance+) Also modifies room clear drops.
(in Repentance and Repentance+) Act of Contrition 5.100.601 Act of Contrition
1
+0.7 tears, grants an Eternal Heart.pngEternal Heart. Allows Angel RoomAngel Rooms to appear even if a Devil Deal has been taken before. Reduces the Devil/Angel room chance penalty for taking Red heart damage.
(in Repentance and Repentance+) Divine Intervention 5.100.568 Divine Intervention
1
Double tapping a fire key creates a shield that pushes away enemies and reflects enemy projectiles and lasers.
(in Repentance and Repentance+) Hallowed Ground 5.100.543 Hallowed Ground
1
Spawns a white poop familiar, which turns into a White Poop.pngWhite Poop when Isaac is hurt. White poop has an aura that increases tear fire rate and can block enemy shots. (in Repentance and Repentance+) The aura also increases damage by 20% and gives homing.
(in Repentance and Repentance+) Immaculate Heart 5.100.573 Immaculate Heart
1
Adds one Red Heart Container and fully restores health. x1.2 damage multiplier. Isaac will occasionally fire extra tears that orbit around him.
(in Repentance and Repentance+) Monstrance 5.100.574 Monstrance
1
Isaac gains an aura that deals damage to enemies inside it.
(in Repentance and Repentance+) Paschal Candle 5.100.567 Paschal Candle
1
Gives Isaac a familiar that grants +0.4 Fire Rate for each consecutive room he's cleared without taking damage. The bonus stacks up to five times.
(in Repentance and Repentance+) Purgatory 5.100.634 Purgatory
1
While in a room with enemies, spawns red cracks in the ground. Walking over these cracks summons ghosts that launch themselves at enemies and explode.
(in Repentance and Repentance+) Revelation 5.100.643 Revelation
1
Grants flight and two Soul Heart.pngSoul Hearts. In addition to tears, Isaac can charge up and fire a powerful holy laser.
(in Repentance and Repentance+) Salvation 5.100.696 Salvation
1
Gives Isaac a halo that summons beams of light on enemies inside it. The halo grows larger the more times Isaac has taken damage this floor.
(in Repentance and Repentance+) Soul Locket 5.100.686 Soul Locket
1
Gives Isaac a permanent stat boost whenever he picks up a Soul Heart.pngSoul Heart.
(in Repentance and Repentance+) Spirit Sword 5.100.579 Spirit Sword
1
Instead of tears, Isaac swings a sword. Charging does a spin attack and fires a projectile, and a projectile is sometimes fired with normal swings if Isaac has no empty Red Heart.pngRed Heart Containers.
(in Repentance and Repentance+) The Stairway 5.100.586 The Stairway
1
Generates a ladder at the start of every floor that leads to a unique Angel RoomAngel Room shop.
(in Repentance and Repentance+) Star of Bethlehem 5.100.651 Star of Bethlehem
1
Spawns a star familiar that slowly travels towards the Boss RoomBoss Room, giving an aura that increases damage and tears and grants homing tears.
(in Repentance and Repentance+) Book of Virtues 5.100.584
Book of Virtues
4 rooms
0.5
Passively causes active items to spawn themed orbital wisp familiars on use, which fire tears and block shots. Can be activated to spawn a basic wisp if Isaac has no other active item.
(in Repentance and Repentance+) Sacred Orb 5.100.691 Sacred Orb
0.5
Prevents items of quality 0-1 from appearing, and items of quality 2 from appearing 33% of the time. Quest items are unaffected.
(in Repentance+) The Halo 5.100.101 The Halo
1
(except in Repentance and Repentance+) Grants one full Red Heart container, +0.3 damage, +0.2 tears, +0.25 range, +0.3 speed, and +0.5 tear falling speed.
(in Repentance and Repentance+) Grants one full Red Heart container, +0.3 damage, +0.2 tears, +1.5 range, and +0.3 speed. Heals 1 additional Red Heart.pngRed Heart.
(in Repentance+) Holy Light 5.100.374 Holy Light
1
Adds a chance to fire holy tears, which will create a damaging light beam in the area if they hit an enemy.
(in Repentance+) Lazarus' Rags 5.100.332 Lazarus' Rags
1
(except in Repentance and Repentance+) Upon dying, resurrect as Character Lazarus Risen icon.pngLazarus Risen in the current room with one Red Heart container and Collectible Anemic icon.pngAnemic.
(in Repentance and Repentance+) Upon dying, resurrect as Character Lazarus Risen icon.pngLazarus Risen in the current room with one less Red Heart container, Collectible Anemic icon.pngAnemic, and +0.5 Damage. Transform into Character Lazarus icon.pngLazarus when reaching the next floor.
(in Repentance+) Lil Delirium 5.100.519 Lil Delirium
1
Grants a familiar that transforms into another random familiar every 10 seconds.
(in Repentance+) The Relic 5.100.98 The Relic
1
Spawns a cross familiar that drops a Soul Heart.pngSoul Heart after clearing enough rooms.
(in Repentance+) Scapular 5.100.142 Scapular
1
Once per room, when Isaac is reduced to his last half heart, he is granted one Soul Heart.pngSoul Heart.
(in Repentance+) The Wafer 5.100.108 The Wafer
1
Most sources of damage that would cause more than one-half heart of damage are reduced to one-half heart instead.