Secret Room (Item Pool)

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Items in this pool can be found in the Secret RoomSecret Room.

Activated Collectibles

Name ID Icon Weight Description
Blank Card 5.100.286
Blank Card
Variable
1
(except in Repentance) Copies the effect of the card or rune currently held by Isaac.
(in Repentance) Copies the effect of the card currently held by Isaac. The charge time is based on the power of the card.
Book of Secrets 5.100.287
Book of Secrets
6 rooms
1
Gives the effect of Collectible Treasure Map icon.pngTreasure Map, Collectible The Compass icon.pngThe Compass, or Collectible Blue Map icon.pngBlue Map for the duration of the current floor. (in Repentance) If all effects are active, Collectible X-Ray Vision icon.pngX-Ray Vision is provided for the floor instead. Highlights any Tinted Rocks and rocks with Crawl SpaceCrawl Space in the room.
Forget Me Now 5.100.127
Forget Me Now
One time use
1
Restarts the current floor with a new layout. Isaac loses Forget Me Now, but keeps other items and consumables picked up on the original floor.
The Necronomicon 5.100.35
The Necronomicon
4 rooms
1
Deals 40 damage to every enemy in the room.
We Need To Go Deeper! 5.100.84
We Need To Go Deeper!
6 rooms
1
Creates a trapdoor to go to the next floor. (in Repentance) Once per floor, using it on tiles with special graphics will instead create a Crawl SpaceCrawl Space.
(in Afterbirth †) Compost 5.100.480
Compost
2 rooms
1
Doubles Isaac's Blue Flies and Blue Spiders, or spawns one if Isaac has none. Converts pickups in the current room into Blue Flies or Blue Spiders.
(in Repentance) Clear Rune 5.100.263
Clear Rune
Variable
1
Has the same effect as the rune or soul stone currently held by Isaac. The charge time is based on the power of the rune.
(in Repentance) Death Certificate 5.100.628
Death Certificate
One time use
1
Takes Isaac to an abandoned and expanded version of HomeHome, which has one copy of every item in the game. After taking an item, Isaac returns to the room he used Death Certificate in.
(in Repentance) D infinity 5.100.489
D infinity
Variable
1
(except in Repentance) Grants a random die item that changes each use.
(in Repentance) Acts as any die item, and can by cycled by pressing the drop key.
(in Repentance) Esau Jr. 5.100.703
Esau Jr.
1 room
1
Swaps between the current character and Esau Jr., who has +2 flat damage and flight. Characters have independent items and health. Dying as either character ends the run.
(in Repentance) Eternal D6 5.100.609
Eternal D6
2 rooms
1
Rerolls all items in the room. Each item has a 25% chance to disappear instead.
(in Repentance) Flip 5.100.711
Flip
6 rooms
1
Item pedestals have a second uninteractable "ghostly" item behind them. Activating will flip the real and ghostly items around. If playing as Character Tainted Lazarus icon.pngTainted Lazarus, also flips between them and Character Dead Tainted Lazarus icon.pngDead Tainted Lazarus.
(in Repentance) Keeper's Box 5.100.719
Keeper's Box
4 rooms
1
Spawns a random shop item or pickup which can be bought for its normal price.
(in Repentance) Mega Mush 5.100.625
Mega Mush
12 rooms
1
Gigantifies Isaac for 30 seconds, increasing damage and range while lowering tears, granting invulnerability, and allowing Isaac to crush enemies and obstacles he walks on. The effect persists between rooms.
(in Repentance) Placebo 5.100.348
Placebo
Variable
1
Has the same effect as the Pill currently held by Isaac. (in Repentance) The charge time is based on the power of the pill.
(in Repentance) Red Key 5.100.580
Red Key
4 rooms
1
Creates a Red RoomRed Room adjacent to a viable wall, indicated by the outline of a door. These rooms have a 10% chance to be a special room.
(in Repentance) R Key 5.100.636
R Key
One time use
1
Brings Isaac back to the first floor of a new run, retaining all of his items.
(in Repentance) Spindown Dice 5.100.723
Spindown Dice
6 rooms
1
Reduces the internal ID number of all items in the room by one, turning them into the item with that number.
(in Repentance) Wavy Cap 5.100.582
Wavy Cap
0.5 seconds
1
Increases fire rate, decreases speed, and distorts the screen. All effects become more pronounced with repeated use, and wear off by clearing rooms.

Passive Collectibles

Name ID Icon Weight Description
1up! 5.100.11 1up!
1
Gives Isaac an extra life. Upon death, he will respawn in the previous room with full health, after which 1up! will disappear.
Black Lotus 5.100.226 Black Lotus
1
Grants one Red Heart Container, one Soul Heart.pngSoul Heart, and one Black Heart.pngBlack Heart.
Cursed Eye 5.100.316 Cursed Eye
1
Grants charged tears that can be fired in a tight burst. Getting hit while charging will teleport Isaac to another room.
Infamy 5.100.242 Infamy
1
Gives Isaac a 50% chance to block projectiles coming from any direction.
Lost Contact 5.100.213 Lost Contact
1
Isaac's tears can hit and destroy enemy projectiles. -0.15 shot speed.
Missing No. 5.100.258 Missing No.
1
Randomizes all passive items and stats upon pickup and at the start of each succeeding floor.
Missing Page 2 5.100.262 Missing Page 2
1
Grants one Black Heart.pngBlack Heart. Upon taking damage that reduces Isaac's health to one heart or less, deals damage to all enemies in the room. (in Repentance) Increases the damage of Black Heart.pngBlack Hearts and Collectible The Necronomicon icon.pngThe Necronomicon-like effects by 40.
Mystery Sack 5.100.271 Mystery Sack
1
Spawns a familiar that drops a Heart, coin, Bomb.pngBomb, or Key.pngKey every 5-6 rooms.
Odd Mushroom 5.100.121 Odd Mushroom
1
(except in Repentance) Grants one empty Heart container, +0.3 damage, +0.25 range, +0.5 tear falling speed, and -0.1 speed.
(in Repentance) Grants one full Heart container, +1 damage, +1.5 range, and -0.2 speed
Odd Mushroom 5.100.120 Odd Mushroom
1
+1.7 tears, +0.3 speed, slightly reduces damage.
Pyro 5.100.190 Pyro
1
Grants 99 Bomb.pngBombs.
Raw Liver 5.100.16 Raw Liver
1
Grants 2 Red Heart containers and completely restores health.
Samson's Chains 5.100.321 Samson's Chains
1
Attaches a ball and chain to Isaac that pulls behind him that damages enemies, blocks shots, and destroys most Obstacles.
Skeleton Key 5.100.17 Skeleton Key
1
Gives Isaac 99 Key.pngKeys.
Transcendence 5.100.20 Transcendence
1
Grants flight.
(except in Repentance) A Quarter 5.100.74 A Quarter
1
Gives Isaac 25 Penny.pngcoins.
(except in Repentance) Bomb Bag 5.100.131 Bomb Bag
1
Spawns a familiar that drops a Bomb.pngBomb every 3 rooms.
(except in Repentance) Mr. Mega 5.100.106 Mr. Mega
1
+5 Bomb.pngBombs. Increases the size, blast radius, and damage of Isaac's bombs.
(except in Repentance) Sack of Pennies 5.100.94 Sack of Pennies
1
Spawns a familiar that drops a Penny.pngcoin every 2 rooms.
(except in Rebirth) GB Bug 5.100.405 GB Bug
1
(except in Repentance) Spawns a familiar that bounces diagonally around the room, applying a random status effect to enemies it hits and has a chance to re-roll pickups it passes over.
(in Repentance) Spawns a familiar that follows Isaac. Double tapping the fire button launches it forward, causing it to reroll the first monster or pickup it hits.
(except in Rebirth) Key Bum 5.100.388 Key Bum
1
Spawns a familiar that follows Isaac and collects Key.pngKeys for himself, giving random Chest.pngChests in return.
(except in Rebirth) Rune Bag 5.100.389 Rune Bag
1
Spawns a familiar that drops a random rune after clearing enough rooms.
(in Afterbirth † and Repentance) Dad's Ring 5.100.546 Dad's Ring
1
Creates a ring of light around Isaac that petrifies enemies in contact.
(in Afterbirth † and Repentance) Eye of Greed 5.100.450 Eye of Greed
1
Every 20 tears, Isaac loses 1 Penny.pngPenny and shoots an additional gold tear that petrifies enemies and turns them into gold. Any enemy killed while in this state will drop coins.
(in Afterbirth † and Repentance) Greed's Gullet 5.100.501 Greed's Gullet
1
Grants a Red Heart container for every 25 Penny.pngCoins Isaac has.
(in Repentance) Astral Projection 5.100.677 Astral Projection
1
Causes Isaac to turn into a ghost if he gets hit while in an uncleared room, giving him flight and spectral tears and blocking the next hit he takes.
(in Repentance) Binge Eater 5.100.664 Binge Eater
1
+1 Red Heart Container and fully heals Isaac. Item pedestals also offer a random food item. Picking up a food item temporarily grants +3.6 damage and permanently boosts 2 stats.
(in Repentance) Chaos 5.100.402 Chaos
1
Drops 1-6 random pickups on the floor. Causes items to be chosen from random item pools.
(in Repentance) Cracked Orb 5.100.675 Cracked Orb
1
Unlocks doors and reveals a random room on the map when Isaac takes damage.
(in Repentance) Echo Chamber 5.100.700 Echo Chamber
1
When Isaac uses a Card, Pill, or Rune, he also uses a copy of the previous three Cards/Pills/Runes he used after picking up Echo Chamber.
(in Repentance) Epic Fetus 5.100.168 Epic Fetus
1
Instead of tears, firing creates a crosshair which can be moved freely. A missile is dropped in the location after 1.5 seconds, exploding for high damage.
(in Repentance) Evil Charm 5.100.632 Evil Charm
1
+2 luck. Provides immunity to burn, confusion, fear, and poison.
(in Repentance) Glitched Crown 5.100.689 Glitched Crown
1
Item pedestals cycle between 5 random items before being picked up.
(in Repentance) Inner Child 5.100.688 Inner Child
1
Upon death, Isaac respawns in the current room with half of a Red Heart.pngRed Heart, a massive size down, and +0.2 Speed.
(in Repentance) Isaac's Tomb 5.100.701 Isaac's Tomb
1
Spawns an Old Chest.pngOld Chest at the start of each floor.
(in Repentance) Keeper's Kin 5.100.717 Keeper's Kin
1
Rocks and other Obstacles spawn blue spiders over time while in a room with enemies, and spawn two blue spiders when destroyed.
(in Repentance) Keeper's Sack 5.100.716 Keeper's Sack
1
Gives range, speed, or damage when buying things from a shop. Spawns three coins and a Key.pngKey on pickup.
(in Repentance) Lost Soul 5.100.612 Lost Soul
1
Creates a ghostly familiar that closely follows behind Isaac. It dies in one hit, but respawns at the start of the next floor. Each time it survives until the next floor, it rewards Isaac with Soul Heart.pngSoul Hearts, Eternal Heart.pngEternal Hearts, or an Item.
(in Repentance) Orphan Socks 5.100.571 Orphan Socks
1
Prevents creep and floor spikes from damaging Isaac. Also gives Isaac +0.3 speed and 2 Soul Heart.pngSoul Hearts.
(in Repentance) Rock Bottom 5.100.562 Rock Bottom
1
Locks Isaac's attributes to their highest values reached.
(in Repentance) Sack Head 5.100.424 Sack Head
1
Spawns a Grab Bag.pngGrab Bag on pickup. Penny.pngCoins, Bomb.pngBombs, Key.pngKeys, cards, runes and batteries have a chance to become Grab Bag.pngGrab Bags.
(in Repentance) Sack of Sacks 5.100.500 Sack of Sacks
1
Spawns a familiar that drops a Grab Bag.pngGrab Bag every 5-6 rooms cleared.
(in Repentance) Sausage 5.100.669 Sausage
1
Adds a Red Heart Container, fully heals Isaac, and gives +0.2 Speed, +0.5 Damage, +0.5 Tears, +2.5 Range, +0.2 Shot Speed, and +1.0 Luck. Increases the chance of encountering a Devil RoomDevil Room, Angel RoomAngel Room, and/or PlanetariumPlanetarium each by 6.9%.
(in Repentance) Spirit Shackles 5.100.674 Spirit Shackles
1
On death, Isaac's ghost is chained to his dead body and he can continue to fight with 1/2 of a heart, returning to life after 10 seconds. After it activates, it must be recharged by picking up a Soul Heart.pngSoul Heart.
(in Repentance) Strawman 5.100.667 Strawman
1
Spawns a controllable Character Keeper icon.pngKeeper to fight enemies alongside Isaac, functioning similarly to Character Jacob and Esau icon.pngJacob and Esau. If Keeper dies, he spawns 5 blue spiders and Strawman is removed from Isaac's inventory.
(in Repentance) TMTRAINER 5.100.721 TMTRAINER
1
Causes all future items to be "glitched", granting them completely random effects.
(in Repentance) Sacred Orb 5.100.691 Sacred Orb
0.5
Prevents items of quality 0-1 from appearing, and items of quality 2 from appearing 33% of the time. Quest items are unaffected.
(in Repentance) Vanishing Twin 5.100.697 Vanishing Twin
0.5
Spawns a familiar that becomes a weaker clone of the floor's boss when entering the Boss RoomBoss Room. Defeating it drops an extra item.