Red Chest (Item Pool)

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Items in this pool can be found in Red Chest.pngRed Chests.

Activated Collectibles

Name ID Icon Weight Description
Guppy's Head 5.100.145
Guppy's Head
1 room
1
Spawns 2-4 friendly Blue Flies that damage enemies.
Guppy's Paw 5.100.133
Guppy's Paw
Unlimited
1
Converts one Red Heart Container into three Soul Heart.pngSoul Hearts.
Pandora's Box 5.100.297
Pandora's Box
One time use
1
Spawns specific pickups or items depending on the floor it is used on. Disappears after use.
(except in Rebirth and Afterbirth) Plan C 5.100.475
Plan C
One time use
(except in Repentance and Repentance+)0.2
(in Repentance and Repentance+)0.1
Kills all enemies in the room, then kills Isaac three seconds later.
(in Repentance and Repentance+) Magic Skin 5.100.642
Magic Skin
6 rooms
1
Consumes one heart container or two Soul Heart.pngSoul Hearts to spawn an item and grant Isaac a broken heart container that can never be filled. If Magic Skin is not held after being used, it is very likely to replace any future items.
(in Repentance and Repentance+) Red Key 5.100.580
Red Key
4 rooms
0.1
Creates a Red RoomRed Room adjacent to a viable wall, indicated by the outline of a door. These rooms have a 10% chance to be a special room.

Passive Collectibles

Name ID Icon Weight Description
Dead Cat 5.100.81 Dead Cat
1
Sets Isaac's Red Heart Containers to 1, but grants 9 extra lives. After dying, Isaac respawns with 1 Red Heart Container.
Guppy's Collar 5.100.212 Guppy's Collar
1
Grants a permanent 50% chance to respawn with 1/2 of a Red Heart.pngRed Heart after death.
Guppy's Tail 5.100.134 Guppy's Tail
1
Room Clear Awards have a 1/3 chance of being replaced with a Chest.pngChest and a 2/9 chance being replaced with nothing.
(in Rebirth) Goat Head 5.100.215 Goat Head
1
A Devil RoomDevil Room / Angel RoomAngel Room will always spawn after every boss fight, excluding the first floor and floors after Chapter 4.
(except in Rebirth) Bob's Curse 5.100.140 Bob's Curse
1
+5 Bomb.pngBombs. Grants Isaac's bombs a poison effect. (in Repentance and Repentance+) They also leave a lingering poison cloud, and Isaac becomes immune to poison.
(except in Rebirth) Curse of the Tower 5.100.371 Curse of the Tower
1
Upon taking damage, spawns six Troll Bomb.pngTroll Bombs around the room, similar to the effect of XVI - The TowerXVI - The Tower.
(except in Rebirth) Cursed Eye 5.100.316 Cursed Eye
1
Grants charged tears that can be fired in a tight burst. Getting hit while charging will teleport Isaac to another room.
(in Repentance and Repentance+) Guppy's Eye 5.100.665 Guppy's Eye
1
Shows the contents of Chest.pngChests, Fire Place.pngFire Places, Grab Bag.pngGrab Bags, and Shopkeeper.pngShopkeepers before they're opened/destroyed.
(in Repentance and Repentance+) Blood Puppy 5.100.565 Blood Puppy
0.5
Spawns a familiar that chases enemies. After killing enough enemies, it becomes more powerful but will also try to hurt Isaac. Dealing enough damage to it returns it to normal.
(in Repentance and Repentance+) False PHD 5.100.654 False PHD
0.2
Converts good pills into bad pills and identifies all pills. Bad pills now have secondary positive effects. Grants one Black Heart.pngBlack Heart.