Boss (Greed Mode Item Pool)

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(except in Rebirth) Greed mode only Greed / (except in Rebirth and Afterbirth) Greedier mode only Greedier Item Pools
(except in Rebirth)

Items in this pool can be found in the silver Treasure RoomTreasure Room or for sale in the ShopShop in Greed mode.

Name ID Icon Weight Description
The Belt 5.100.28 The Belt
1
 +0.3 speed.
Binky 5.100.438 Binky
1
 Grants one Soul Heart.pngSoul Heart, +0.75 tears and decreases Isaac's size.
Blood Clot 5.100.254 Blood Clot
1
 (except in Repentance and Repentance+) Tears fired from the left eye have +1 flat damage, +5 range, and +0.5 tear falling speed.
(in Repentance and Repentance+) Tears fired from the left eye have +1 flat damage and +2.75 range.
Blue Cap 5.100.342 Blue Cap
1
 Gives one full Red Heart container, +0.7 tears, and -0.16 shot speed. (in Repentance and Repentance+) Heals 1 additional Red Heart.pngRed Heart.
Box 5.100.198 Box
1
 Spawns various pickups: 1 Penny.pngcoin, 1 Key.pngKey, 1 Bomb.pngBomb, 1 Red Heart.pngHeart, 1 card/rune, 1 pill and 1 trinket.
Breakfast 5.100.25 Breakfast
1
 Grants one full Red Heart container. (in Repentance and Repentance+) Heals 1 additional Red Heart.pngRed Heart.
Caffeine Pill 5.100.340 Caffeine Pill
1
 Grants +0.3 speed, reduces Isaac's size, and gives a random pill.
Crack Jacks 5.100.354 Crack Jacks
1
 Grants one full Red Heart container and drops a random trinket. (in Repentance and Repentance+) Heals 1 additional Red Heart.pngRed Heart.
Cube of Meat 5.100.73 Cube of Meat
1
 Creates an orbital familiar. Collecting additional copies gives it the ability to shoot tears, then chase enemies to deal contact damage, then deal even more contact damage.
Dessert 5.100.24 Dessert
1
 Grants one full Red Heart container. (in Repentance and Repentance+) Heals 1 additional Red Heart.pngRed Heart.
Dinner 5.100.23 Dinner
1
 Grants one full Red Heart container. (in Repentance and Repentance+) Heals 1 additional Red Heart.pngRed Heart.
Experimental Treatment 5.100.240 Experimental Treatment
1
 (in Rebirth and Afterbirth) Randomly increases and decreases some of Isaac's stats.
(except in Rebirth and Afterbirth) Increases four random stats and decreases the other two.
Growth Hormones 5.100.70 Growth Hormones
1
 (except in Repentance and Repentance+) +1 damage, +0.4 speed.
(in Repentance and Repentance+) +1 damage, +0.2 speed.
Jesus Juice 5.100.197 Jesus Juice
1
 (except in Repentance and Repentance+) +0.5 damage, +0.25 range, +0.5 tear falling speed.
(in Repentance and Repentance+) +0.5 damage, +1.5 range.
Latch Key 5.100.343 Latch Key
1
 Grants 1 Soul Heart.pngSoul Heart and +1 luck. Spawns 2 Key.pngKeys.
A Lump of Coal 5.100.132 A Lump of Coal
1
 The more distance tears travel, the more damage they will do.
Lunch 5.100.22 Lunch
1
 Grants one full Red Heart container. (in Repentance and Repentance+) Heals 1 additional Red Heart.pngRed Heart.
Magic 8 Ball 5.100.194 Magic 8 Ball
1
 +0.16 shot speed, spawns a random tarot card. (in Repentance and Repentance+) Increases the chance of finding a PlanetariumPlanetarium.
Magic Scab 5.100.253 Magic Scab
1
 Grants one full Red Heart container, +1 luck. (in Repentance and Repentance+) Heals 1 additional Red Heart.pngRed Heart.
Match Book 5.100.344 Match Book
1
 Grants Isaac one Black Heart.pngBlack Heart, spawns two or three Bomb.pngBombs. (in Repentance and Repentance+) Also spawns Match StickMatch Stick if it hasn't been encountered yet.
MEAT! 5.100.193 MEAT!
1
 Grants one full Red Heart container, +0.3 damage. (in Repentance and Repentance+) Heals 1 additional Red Heart.pngRed Heart
Mini Mush 5.100.71 Mini Mush
1
 Decreases Isaac's size, making him less likely to be hit. (except in Repentance and Repentance+) +0.3 speed, +1.5 tear falling speed, -4.25 range (effective range is increased). (in Repentance and Repentance+) +0.3 speed, +2.5 range.
Mom's Coin Purse 5.100.195 Mom's Coin Purse
1
 Spawns 4 random pills near Isaac.
Mom's Heels 5.100.30 Mom's Heels
1
 (except in Repentance and Repentance+) +5.25 range, +0.5 tear falling speed.
(in Repentance and Repentance+) +2.5 range, enemies that touch Isaac take 12 damage.
Mom's Lipstick 5.100.31 Mom's Lipstick
1
 (except in Repentance and Repentance+) +5.25 range, +0.5 tear falling speed.
(in Repentance and Repentance+) +3.75 range. Spawns a Red Heart.pngHeart on pickup.
Mom's Pearls 5.100.355 Mom's Pearls
1
 (except in Repentance and Repentance+) +1.25 range, +0.5 tear falling speed, +1 luck.
(in Repentance and Repentance+) +2.5 range, +1 luck. Grants one Soul Heart.pngSoul Heart.
Mom's Underwear 5.100.29 Mom's Underwear
1
 (except in Repentance and Repentance+) +5.25 range, +0.5 tear falling speed.
(in Repentance and Repentance+) +2.5 range. Spawns 3-6 Blue Flies on pickup.
Mr. Dolly 5.100.370 Mr. Dolly
1
 (except in Repentance and Repentance+) +0.7 tears, +5.25 range, +0.5 tear falling speed, Spawns a combination of 3 Red Heart.pngRed Hearts, Soul Heart.pngSoul Hearts or Black Heart.pngBlack Hearts on the floor when picked up.
(in Repentance and Repentance+) +0.7 tears, +2.5 range, spawns 3 random types of Red Heart.pngHearts on the floor when picked up.
Odd Mushroom 5.100.120 Odd Mushroom
1
 +1.7 tears, +0.3 speed, slightly reduces damage.
Roid Rage 5.100.14 Roid Rage
1
 (except in Repentance and Repentance+) +0.6 speed, +5.25 range, +0.5 tear falling speed.
(in Repentance and Repentance+) +0.3 speed, +2.5 range
Rotten Meat 5.100.26 Rotten Meat
1
 Grants one full Red Heart container. (in Repentance and Repentance+) Heals 1 additional Red Heart.pngRed Heart.
Safety Pin 5.100.339 Safety Pin
1
 (except in Repentance and Repentance+) Grants one Black Heart.pngBlack Heart, +5.25 range, +0.5 tear falling speed, +0.16 shot speed.
(in Repentance and Repentance+) Grants one Black Heart.pngBlack Heart, +2.5 range, +0.16 shot speed.
Screw 5.100.255 Screw
1
 +0.5 tears, +0.2 shot speed.
A Snack 5.100.346 A Snack
1
 Grants one full Red Heart container. (in Repentance and Repentance+) Heals 1 additional Red Heart.pngRed Heart.
Speed Ball 5.100.143 Speed Ball
1
 +0.3 speed, +0.2 shot speed.
Squeezy 5.100.196 Squeezy
1
 +0.4 tears, spawns 2 Soul Heart.pngSoul Hearts.
Stem Cells 5.100.176 Stem Cells
1
 Grants one full Red Heart container and +0.16 shot speed. (in Repentance and Repentance+) Heals 1 additional Red Heart.pngRed Heart
Synthoil 5.100.345 Synthoil
1
 (except in Repentance and Repentance+) +1 damage, +5.25 range, +0.5 tear falling speed.
(in Repentance and Repentance+) +1 damage, +2.5 range.
Tooth Picks 5.100.183 Tooth Picks
1
 +0.7 tears, +0.16 shot speed.
Torn Photo 5.100.341 Torn Photo
1
 +0.7 tears, +0.16 shot speed.
Wire Coat Hanger 5.100.32 Wire Coat Hanger
1
 +0.7 tears.
Wooden Spoon 5.100.27 Wooden Spoon
1
 +0.3 speed.
The Halo 5.100.101 The Halo
(except in Repentance and Repentance+) 1
(in Repentance and Repentance+) 0.5
 (except in Repentance and Repentance+) Grants one full Red Heart container, +0.3 damage, +0.2 tears, +0.25 range, +0.3 speed, and +0.5 tear falling speed.
(in Repentance and Repentance+) Grants one full Red Heart container, +0.3 damage, +0.2 tears, +1.5 range, and +0.3 speed. Heals 1 additional Red Heart.pngRed Heart.
PJs 5.100.428 PJs
(except in Repentance and Repentance+) 1
(in Repentance and Repentance+) 0.5
 Grants 4 Soul Heart.pngSoul Hearts and fully restores Isaac's health.
Raw Liver 5.100.16 Raw Liver
(except in Repentance+) 1
(in Repentance+) 0.2
 Grants 2 Red Heart containers and completely restores health.
(except in Repentance and Repentance+) 1up! 5.100.11 1up!
1
 Gives Isaac an extra life. Upon death, he will respawn in the previous room with full health, after which 1up! will disappear.
(except in Repentance and Repentance+) Mom's Key 5.100.199 Mom's Key
1
 Adds 2 keys. Chest.pngChests will drop additional pickups.
(except in Repentance+) <3 5.100.15 <3
1
 Grants Isaac one Red Heart container and fully restores Isaac's health.
(except in Repentance+) Thunder Thighs 5.100.314 Thunder Thighs
1
 Destroys rocks upon contact with Isaac. Adds one Red Heart container and lowers Speed.
(except in Rebirth and Afterbirth) Dad's Lost Coin 5.100.455 Dad's Lost Coin
1
 (except in Repentance and Repentance+) +1.5 range, +1 tear falling speed. Drops a Lucky Penny.
(in Repentance and Repentance+) +2.5 range. Drops a Lucky Penny.
(except in Rebirth and Afterbirth) Midnight Snack 5.100.456 Midnight Snack
1
 Grants one full Red Heart container. (in Repentance and Repentance+) Heals 1 additional Red Heart.pngRed Heart.
(except in Rebirth and Afterbirth) Marbles 5.100.538 Marbles
1
 Spawns 3 random trinkets. Taking damage has a 5% chance to swallow Isaac's currently held trinket, gaining its effect permanently.
(except in Rebirth and Afterbirth) Marrow 5.100.541 Marrow
1
 Grants one Bone Heart.pngBone Heart and spawns three Red Heart.pngRed Hearts.
(except in Rebirth and Afterbirth) Divorce Papers 5.100.547 Divorce Papers
1
 Grants one Bone Heart.pngBone Heart, +0.7 tears, spawns a Mysterious PaperMysterious Paper.
(in Afterbirth †) Belly Button 5.100.458 Belly Button
1
 Drops a random trinket. Grants a second trinket slot.
(in Afterbirth †) Polydactyly 5.100.454 Polydactyly
1
 Allows Isaac to carry two cards, pills, or any combination of both. Spawns one random card, rune, or pill.
(in Repentance and Repentance+) Ball of Bandages 5.100.207 Ball of Bandages
1
 Creates an orbital familiar. Collecting additional copies gives it the ability to shoot Charm tears, then chase enemies to deal contact damage, then deal even more contact damage.
(in Repentance and Repentance+) A Bar of Soap 5.100.564 A Bar of Soap
1
 +0.5 Tears, +0.2 Shot Speed.
(in Repentance and Repentance+) Booster Pack 5.100.624 Booster Pack
1
 Drops 5 random cards.
(in Repentance and Repentance+) Consolation Prize 5.100.644 Consolation Prize
1
 Increases Isaac's lowest stat and drops either 3 Penny.pngCoins, 1 Bomb.pngBomb, or 1 Key.pngKey depending on what Isaac has the least of.
(in Repentance and Repentance+) Eye Drops 5.100.600 Eye Drops
1
 Increases the fire rate in Isaac's left eye, causing his eyes to fire at different rates.
(in Repentance and Repentance+) Glass Eye 5.100.730 Glass Eye
1
 +0.75 damage, +1 luck.
(in Repentance and Repentance+) Odd Mushroom 5.100.121 Odd Mushroom
1
 (except in Repentance and Repentance+) Grants one empty Heart container, +0.3 damage, +0.25 range, +0.5 tear falling speed, and -0.1 speed.
(in Repentance and Repentance+) Grants one full Heart container, +1 damage, +1.5 range, and -0.2 speed.
(in Repentance and Repentance+) Stapler 5.100.708 Stapler
1
 +1 Damage. Prevents Isaac from firing tears from his left eye, like Character Cain icon.pngCain.
(in Repentance and Repentance+) Stye 5.100.731 Stye
1
 Tears fired from Isaac's right eye have +28% Damage, +6.5 Range, and -0.3 Shot Speed.
(in Repentance and Repentance+) Supper 5.100.707 Supper
1
 Grants one full Red Heart container. Heals 1 additional Red Heart.pngRed Heart.
(in Repentance and Repentance+) Tropicamide 5.100.659 Tropicamide
1
 +2.5 Range, Increases tear size.
(in Repentance and Repentance+) Magic Mushroom 5.100.12 Magic Mushroom
0.2
 (except in Repentance and Repentance+) Makes Isaac bigger. Adds one Red Heart Container, +0.3 Damage, x1.5 damage multiplier, +5.25 Range, +0.3 Speed, and restores all Health.
(in Repentance and Repentance+) Makes Isaac bigger. Adds one Red Heart Container, +0.3 Damage, x1.5 damage multiplier, +2.5 Range, +0.3 Speed, and restores all Health.
(in Repentance+) Cat-o-nine-tails 5.100.165 Cat-o-nine-tails
1
 +1 damage, +0.23 shot speed.
(in Repentance+) Old Bandage 5.100.219 Old Bandage
1
 Grants an empty Red Heart container. Adds a chance of dropping a Red Heart.pngRed Heart after taking damage.
(in Repentance+) Pentagram 5.100.51 Pentagram
1
 +1 damage, increases Devil RoomDevil Room / Angel RoomAngel Room chance by 10%.
(in Repentance+) Placenta 5.100.218 Placenta
1
 Grants one full Red Heart container, and a chance to regenerate a Half Red Heart.pngHalf Red Heart of health every minute of gameplay.
(in Repentance+) Super Bandage 5.100.92 Super Bandage
0.5
 Grants one full Red Heart container and 2 Soul Heart.pngSoul Hearts.


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