Boss (Greed Mode Item Pool)

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(except in Rebirth)

Items in this pool can be found in the silver Treasure RoomTreasure Room or for sale in the ShopShop in Greed mode.

Name ID Icon Weight Description
<3 5.100.15 <3
1
Grants Isaac one Red Heart container and fully restores Isaac's health.
The Belt 5.100.28 The Belt
1
+0.3 speed.
Binky 5.100.438 Binky
1
Grants one Soul Heart.pngSoul Heart, +0.75 tears and decreases Isaac's size.
Blood Clot 5.100.254 Blood Clot
1
(except in Repentance)Tears fired from the left eye have +1 flat damage, +5 range, and +0.5 tear falling speed.
(in Repentance)Tears fired from the left eye have +1 flat damage and +2.75 range.
Blue Cap 5.100.342 Blue Cap
1
Gives one full Red Heart container, +0.7 tears, and -0.16 shot speed. (in Repentance) Heals 1 additional Red Heart.pngRed Heart.
Box 5.100.198 Box
1
Spawns various pickups: 1 Penny.pngcoin, 1 Key.pngKey, 1 Bomb.pngBomb, 1 Red Heart.pngHeart, 1 card/rune, 1 pill and 1 trinket.
Breakfast 5.100.25 Breakfast
1
Grants one full Red Heart container. (in Repentance) Heals 1 additional Red Heart.pngRed Heart.
Caffeine Pill 5.100.340 Caffeine Pill
1
Grants +0.3 speed, reduces Isaac's size, and gives a random pill.
Crack Jacks 5.100.354 Crack Jacks
1
Grants one full Red Heart container and drops a random trinket. (in Repentance) Heals 1 additional Red Heart.pngRed Heart.
Cube of Meat 5.100.73 Cube of Meat
1
Creates an orbital familiar. Collecting additional copies gives it the ability to shoot tears, then chase enemies to deal contact damage, then deal even more contact damage.
Dessert 5.100.24 Dessert
1
Grants one full Red Heart container. (in Repentance) Heals 1 additional Red Heart.pngRed Heart.
Dinner 5.100.23 Dinner
1
Grants one full Red Heart container. (in Repentance) Heals 1 additional Red Heart.pngRed Heart.
Experimental Treatment 5.100.240 Experimental Treatment
1
(in Rebirth and Afterbirth) Randomly increases and decreases some of Isaac's stats.
(in Afterbirth † and Repentance) Increases four random stats and decreases the other two.
Growth Hormones 5.100.70 Growth Hormones
1
(except in Repentance) +1 damage, +0.4 speed.
(in Repentance) +1 damage, +0.2 speed.
Jesus Juice 5.100.197 Jesus Juice
1
(except in Repentance) +0.5 damage, +0.25 range, +0.5 tear falling speed.
(in Repentance) +0.5 damage, +1.5 range.
Latch Key 5.100.343 Latch Key
1
Grants 1 Soul Heart.pngSoul Heart and +1 luck. Spawns 2 Key.pngKeys.
A Lump of Coal 5.100.132 A Lump of Coal
1
The more distance tears travel, the more damage they will do.
Lunch 5.100.22 Lunch
1
Grants one full Red Heart container. (in Repentance) Heals 1 additional Red Heart.pngRed Heart.
Magic 8 Ball 5.100.194 Magic 8 Ball
1
+0.16 shot speed, spawns a random tarot card. (in Repentance) Increases the chance of finding a PlanetariumPlanetarium.
Magic Scab 5.100.253 Magic Scab
1
Grants one full Red Heart container, +1 luck. (in Repentance) Heals 1 additional Red Heart.pngRed Heart.
Match Book 5.100.344 Match Book
1
Grants Isaac one Black Heart.pngBlack Heart, spawns two or three Bomb.pngBombs. (in Repentance) Also spawns Match StickMatch Stick if it hasn't been encountered yet.
MEAT! 5.100.193 MEAT!
1
Grants one full Red Heart container, +0.3 damage. (in Repentance) Heals 1 additional Red Heart.pngRed Heart
Mini Mush 5.100.71 Mini Mush
1
Decreases Isaac's size, making him less likely to be hit. (except in Repentance)+0.3 speed, +1.5 tear falling speed, -4.25 range (effective range is increased). (in Repentance) +0.3 speed, +2.5 range.
Mom's Coin Purse 5.100.195 Mom's Coin Purse
1
Spawns 4 random pills near Isaac.
Mom's Heels 5.100.30 Mom's Heels
1
(except in Repentance) +5.25 range, +0.5 tear falling speed.
(in Repentance) +2.5 range, enemies that touch Isaac take 12 damage.
Mom's Lipstick 5.100.31 Mom's Lipstick
1
(except in Repentance)+5.25 range, +0.5 tear falling speed.
(in Repentance) +3.75 range. Spawns a Red Heart.pngHeart on pickup.
Mom's Pearls 5.100.355 Mom's Pearls
1
(except in Repentance) +1.25 range, +0.5 tear falling speed, +1 luck.
(in Repentance) +2.5 range, +1 luck. Grants one Soul Heart.pngSoul Heart.
Mom's Underwear 5.100.29 Mom's Underwear
1
(except in Repentance) +5.25 range, +0.5 tear falling speed.
(in Repentance) +2.5 range. Spawns 3-6 Blue Flies on pickup.
Mr. Dolly 5.100.370 Mr. Dolly
1
(except in Repentance) +0.7 tears, +5.25 range, +0.5 tear falling speed, Spawns a combination of 3 Red Heart.pngRed Hearts, Soul Heart.pngSoul Hearts or Black Heart.pngBlack Hearts on the floor when picked up.
(in Repentance) +0.7 tears, +2.5 range, spawns 3 random types of Red Heart.pngHearts on the floor when picked up.
Odd Mushroom 5.100.120 Odd Mushroom
1
+1.7 tears, +0.3 speed, slightly reduces damage.
Raw Liver 5.100.16 Raw Liver
1
Grants 2 Red Heart containers and completely restores health.
Roid Rage 5.100.14 Roid Rage
1
(except in Repentance) +0.6 speed, +5.25 range, +0.5 tear falling speed.
(in Repentance) +0.3 speed, +2.5 range
Rotten Meat 5.100.26 Rotten Meat
1
Grants one full Red Heart container. (in Repentance) Heals 1 additional Red Heart.pngRed Heart.
Safety Pin 5.100.339 Safety Pin
1
(except in Repentance) Grants one Black Heart.pngBlack Heart, +5.25 range, +0.5 tear falling speed, +0.16 shot speed.
(in Repentance) Grants one Black Heart.pngBlack Heart, +2.5 range, +0.16 shot speed.
Screw 5.100.255 Screw
1
+0.5 tears, +0.2 shot speed.
A Snack 5.100.346 A Snack
1
Grants one full Red Heart container. (in Repentance) Heals 1 additional Red Heart.pngRed Heart.
Speed Ball 5.100.143 Speed Ball
1
+0.3 speed, +0.2 shot speed.
Squeezy 5.100.196 Squeezy
1
+0.4 tears, spawns 2 Soul Heart.pngSoul Hearts.
Stem Cells 5.100.176 Stem Cells
1
Grants one full Red Heart container and +0.16 shot speed. (in Repentance) Heals 1 additional Red Heart.pngRed Heart
Synthoil 5.100.345 Synthoil
1
(except in Repentance) +1 damage, +5.25 range, +0.5 tear falling speed.
(in Repentance) +1 damage, +2.5 range.
Thunder Thighs 5.100.314 Thunder Thighs
1
Destroys rocks upon contact with Isaac. Adds one Red Heart container and lowers Speed.
Tooth Picks 5.100.183 Tooth Picks
1
+0.7 tears, +0.16 shot speed.
Torn Photo 5.100.341 Torn Photo
1
+0.7 tears, +0.16 shot speed.
Wire Coat Hanger 5.100.32 Wire Coat Hanger
1
+0.7 tears.
Wooden Spoon 5.100.27 Wooden Spoon
1
+0.3 speed.
The Halo 5.100.101 The Halo
(except in Repentance)1
(in Repentance)0.5
(except in Repentance) Grants one full Red Heart container, +0.3 damage, +0.2 tears, +0.25 range, +0.3 speed, and +0.5 tear falling speed.
(in Repentance) Grants one full Red Heart container, +0.3 damage, +0.2 tears, +1.5 range, and +0.3 speed. Heals 1 additional Red Heart.pngRed Heart.
PJs 5.100.428 PJs
(except in Repentance)1
(in Repentance)0.5
Grants 4 Soul Heart.pngSoul Hearts and fully restores Isaac's health.
(except in Repentance) 1up! 5.100.11 1up!
1
Gives Isaac an extra life. Upon death, he will respawn in the previous room with full health, after which 1up! will disappear.
(except in Repentance) Mom's Key 5.100.199 Mom's Key
1
Adds 2 keys. Chest.pngChests will drop additional pickups.
(in Afterbirth † and Repentance) Dad's Lost Coin 5.100.455 Dad's Lost Coin
1
(except in Repentance)+1.5 range, +1 tear falling speed. Drops a Lucky Penny.
(in Repentance)+2.5 range. Drops a Lucky Penny.
(in Afterbirth † and Repentance) Midnight Snack 5.100.456 Midnight Snack
1
Grants one full Red Heart container. (in Repentance) Heals 1 additional Red Heart.pngRed Heart.
(in Afterbirth † and Repentance) Marbles 5.100.538 Marbles
1
Spawns 3 random trinkets. Taking damage has a 5% chance to swallow Isaac's currently held trinket, gaining its effect permanently.
(in Afterbirth † and Repentance) Marrow 5.100.541 Marrow
1
Grants one Bone Heart.pngBone Heart and spawns three Red Heart.pngRed Hearts.
(in Afterbirth † and Repentance) Divorce Papers 5.100.547 Divorce Papers
1
Grants one Bone Heart.pngBone Heart, +0.7 tears, spawns a Mysterious PaperMysterious Paper.
(in Afterbirth †) Belly Button 5.100.458 Belly Button
1
Drops a random trinket. Grants a second trinket slot.
(in Afterbirth †) Polydactyly 5.100.454 Polydactyly
1
Allows Isaac to carry two cards, pills, or any combination of both. Spawns one random card, rune, or pill.
(in Repentance) Ball of Bandages 5.100.207 Ball of Bandages
1
Creates an orbital familiar. Collecting additional copies gives it the ability to shoot Charm tears, then chase enemies to deal contact damage, then deal even more contact damage.
(in Repentance) A Bar of Soap 5.100.564 A Bar of Soap
1
+0.5 Tears, +0.2 Shot Speed.
(in Repentance) Booster Pack 5.100.624 Booster Pack
1
Drops 5 random cards.
(in Repentance) Consolation Prize 5.100.644 Consolation Prize
1
Increases Isaac's lowest stat and drops either 3 Penny.pngCoins, 1 Bomb.pngBomb, or 1 Key.pngKey depending on what Isaac has the least of.
(in Repentance) Eye Drops 5.100.600 Eye Drops
1
Increases the fire rate in Isaac's left eye, causing his eyes to fire at different rates.
(in Repentance) Glass Eye 5.100.730 Glass Eye
1
+0.75 damage, +1 luck.
(in Repentance) Odd Mushroom 5.100.121 Odd Mushroom
1
(except in Repentance) Grants one empty Heart container, +0.3 damage, +0.25 range, +0.5 tear falling speed, and -0.1 speed.
(in Repentance) Grants one full Heart container, +1 damage, +1.5 range, and -0.2 speed
(in Repentance) Stapler 5.100.708 Stapler
1
+1 Damage. Prevents Isaac from firing tears from his left eye, like Character Cain icon.pngCain.
(in Repentance) Stye 5.100.731 Stye
1
Tears fired from Isaac's right eye have +28% Damage, +6.5 Range, and -0.3 Shot Speed.
(in Repentance) Supper 5.100.707 Supper
1
Grants one full Red Heart container. Heals 1 additional Red Heart.pngRed Heart.
(in Repentance) Tropicamide 5.100.659 Tropicamide
1
+2.5 Range, Increases tear size.
(in Repentance) Magic Mushroom 5.100.12 Magic Mushroom
0.2
(except in Repentance) Makes Isaac bigger. Adds one Red Heart Container, +0.3 Damage, x1.5 damage multiplier, +5.25 Range, +0.3 Speed, and restores all Health.
(in Repentance) Makes Isaac bigger. Adds one Red Heart Container, +0.3 Damage, x1.5 damage multiplier, +2.5 Range, +0.3 Speed, and restores all Health.