Item Tags nolostbr

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(in Repentance and Repentance+)

Items with this tag are not available to Character The Lost icon.pngThe Lost after obtaining BirthrightBirthright. Most of these are health-related or related to "on hit" effects, since The Lost has no health. Some of these are also related to abilities The Lost already has, such as spectral tears or flight.

Activated Collectibles

Name ID Icon Quote Description Quality
Blood Rights 5.100.186
Blood Rights
Unlimited
 Mass enemy damage at a cost Takes a full heart of health and deals 40 damage to all enemies in the room. (in Repentance and Repentance+) Repeated uses in the same room only take half a heart.
0
Book of Revelations 5.100.78
Book of Revelations
6 rooms
 Reusable soul protection Increases the chance of a Devil RoomDevil Room / Angel RoomAngel Room appearing while held. Upon use, gives one Soul Heart.pngSoul Heart, and replaces the boss of the current floor with a Harbinger if possible.
3
Breath of Life 5.100.326
Breath of Life
3 seconds
 Invincibility at a cost Grants a brief moment of invincibility when the charge bar hits zero. Isaac begins taking damage if the item is held any longer. (in Repentance and Repentance+) Isaac creates beams of light when touching enemies while invulnerable, and creates a powerful 4-way beam if blocking damage exactly as the invincibility starts.
1
Clicker 5.100.482
Clicker
6 rooms
 Change Transforms Isaac into another random character and removes the last item collected.
0
Converter 5.100.296
Converter
3 rooms
 Convert your soul (except in Repentance and Repentance+) Converts two Soul Heart.pngSoul Hearts or Black Heart.pngBlack Hearts into one filled Red Heart.pngRed Heart Container.
(in Repentance and Repentance+) Converts one Soul Heart.pngSoul Heart or Black Heart.pngBlack Heart into one filled Red Heart.pngRed Heart Container.
(except in Repentance+) 2
(in Repentance+) 1
Guppy's Paw 5.100.133
Guppy's Paw
Unlimited
 Soul converter Converts one Red Heart Container into three Soul Heart.pngSoul Hearts.
3
IV Bag 5.100.135
IV Bag
Unlimited
 Portable blood bank Damages Isaac and spawns a random amount of coins, similar to a Blood Donation Machine.pngBlood Donation Machine.
(except in Repentance+) 1
(in Repentance+) 2
Kamikaze! 5.100.40
Kamikaze!
Unlimited
 Become the bomb! Creates an explosion around Isaac, damaging him and nearby enemies as well as destroying obstacles.
0
Potato Peeler 5.100.487
Potato Peeler
Unlimited
 A pound of flesh Removes a Heart Container, increases damage and range, and grants a Cube of MeatCube of Meat.
2
Prayer Card 5.100.146
Prayer Card
6 rooms
 Reusable eternity Gives Isaac an Eternal Heart.pngEternal Heart.
3
Razor Blade 5.100.126
Razor Blade
Unlimited
 Feel my pain Damages Isaac for one heart and grants +1.2 damage for the current room. (in Repentance and Repentance+) Subsequent uses in the same room only take half a heart.
0
Sumptorium 5.100.713
Sumptorium
10 seconds
 Blood to blood Removes half a heart and creates a Clot familiar that mimics Isaac's movements and tear effects. As Character Tainted Eve icon.pngTainted Eve, passively converts health into Clots while firing. Activating returns all Clots to health.
3
The Jar 5.100.290
The Jar
Unlimited
 Save your life When at full health, up to 4 extra Red Heart.pngRed Hearts can be stored in The Jar. Activating drops the stored hearts on the ground.
0
Yuck Heart 5.100.639
Yuck Heart
4 rooms
 Gross! Grants Isaac a Rotten Heart.pngRotten Heart.
1
Yum Heart 5.100.45
Yum Heart
4 rooms
 Reusable regeneration Restores one full Red Heart.pngRed Heart.
1
(in Repentance+) How to Jump 5.100.282
How to Jump
Unlimited
 It's time you learned how Isaac jumps in the direction he is currently moving, allowing travel over obstacles and enemies.
1
(in Repentance+) The Bible 5.100.33
The Bible
4 rooms
 Temporary flight Grants flight for the current room. Instantly kills Boss Mom ingame.pngMom, Boss Mom's Heart ingame.pngMom's Heart, and Boss It Lives! ingame.pngIt Lives! when activated, but kills Isaac when used on Boss Satan ingame.pngSatan.
1
(except in Repentance+) Satanic Bible 5.100.292
Satanic Bible
6 rooms
 Reusable evil... but at what cost? Grants one Black Heart.pngBlack Heart. (in Repentance and Repentance+) Replaces the boss room item on the current floor with a Devil Deal.
4

Passive Collectibles

Name ID Icon Quote Description Quality
<3 5.100.15 <3 HP up Grants Isaac one Red Heart container and fully restores Isaac's health.
2
A Snack 5.100.346 A Snack HP up Grants one full Red Heart container. (in Repentance and Repentance+) Heals 1 additional Red Heart.pngRed Heart.
1
Adrenaline 5.100.493 Adrenaline Panic = power Increases damage based on how many empty Red Heart containers Isaac has.
(except in Repentance+) 2
(in Repentance+) 1
Anemic 5.100.214 Anemic Toxic blood After Isaac is damaged, a trail of red creep will be left behind him until he leaves the current room. (except in Repentance and Repentance+) +5 range. (in Repentance and Repentance+) +1.5 range.
1
Ankh 5.100.161 Ankh Eternal life? Upon death, Isaac will respawn as Character ??? icon.png??? in the previous room, with 3 Soul Heart.pngSoul Hearts.
(except in Repentance+) 1
(in Repentance+) 0
Astral Projection 5.100.677 Astral Projection The true out-of-body experience! Causes Isaac to turn into a ghost if he gets hit while in an uncleared room, giving him flight and spectral tears and blocking the next hit he takes.
(except in Repentance+) 2
(in Repentance+) 1
Best Bud 5.100.274 Best Bud Sworn protector When hit, spawns a quickly orbiting attack fly similar to Forever aloneForever alone for the current room that deals high damage.
0
Binge Eater 5.100.664 Binge Eater All you can eat +1 Red Heart Container and fully heals Isaac. Item pedestals also offer a random food item. Picking up a food item temporarily grants +3.6 damage and permanently boosts 2 stats.
4
Bird Cage 5.100.610 Bird Cage Fat buddy The first time Isaac takes damage in a room, a familiar leaps on an enemy, dealing damage and releasing a rock wave. For the rest of the room, it chases enemies similar to Dead BirdDead Bird.
(except in Repentance+) 1
(in Repentance+) 0
Black Lotus 5.100.226 Black Lotus HP up x3! Grants one Red Heart Container, one Soul Heart.pngSoul Heart, and one Black Heart.pngBlack Heart.
2
Blood Bag 5.100.119 Blood Bag HP up Grants one filled Red Heart container, restores (except in Repentance and Repentance+) 4 / (in Repentance and Repentance+) 5 Red Heart.pngRed Hearts, and increases speed by 0.3.
2
Blood Bombs 5.100.614 Blood Bombs Bloody blast + HP up Grants a Red Heart container and restores 5 hearts. Bombs leave behind damaging red creep. Isaac can place Bomb.pngBombs at the cost of half a heart if he doesn't have any.
2
Blood Oath 5.100.569 Blood Oath Bleed me dry Stabs Isaac at the beginning of each floor, draining his Red Heart.pngRed Hearts. Increases damage and speed for the floor based on the amount drained.
1
Bloody Gust 5.100.695 Bloody Gust May your rage bring haste The first 6 times Isaac takes damage on a given floor, he gains Speed and Fire Rate for the rest of the floor, up to a maximum of +1.02 and +3.00, respectively.
2
Bloody Lust 5.100.157 Bloody Lust RAGE! Increases Isaac's damage whenever he takes damage, up to six times. The bonus resets when entering a new floor.
2
Bozo 5.100.513 Bozo Party time! +0.1 flat damage, grants a Soul Heart.pngSoul Heart. Enemies can randomly become briefly charmed or feared. Taking damage has a chance to spawn a Rainbow Poop.pngRainbow Poop.
2
Breakfast 5.100.25 Breakfast HP up Grants one full Red Heart container. (in Repentance and Repentance+) Heals 1 additional Red Heart.pngRed Heart.
1
Bucket of Lard 5.100.129 Bucket of Lard HP up (except in Repentance and Repentance+) Grants two empty Red Heart containers, heals Isaac for a Half Red Heart.pngHalf Red Heart, -0.2 speed.
(in Repentance and Repentance+) Grants two Red Heart containers, -0.2 speed.
1
Cambion Conception 5.100.412 Cambion Conception Feed them hate After taking damage a certain amount of times, a permanent demonic familiar spawns.
(except in Repentance+) 2
(in Repentance+) 1
Cancer 5.100.301 Cancer HP up + you feel protected Adds 3 Soul Heart.pngSoul Hearts. Grants The WaferThe Wafer effect for the current room after taking damage.
3
Candy Heart 5.100.671 Candy Heart Power of love Gives Isaac a permanent stat boost whenever he heals with Red Heart.pngRed Heart pickups.
1
Celtic Cross 5.100.162 Celtic Cross Blessing of protection Grants a chance to trigger the Book of ShadowsBook of Shadows effect upon taking damage, creating a shield that nullifies all types of damage for 7 seconds.
1
Charm of the Vampire 5.100.62 Charm of the Vampire DMG up + kills heal Heals Isaac for a Half Red Heart.pngHalf Red Heart for every 13 enemies killed. (in Repentance and Repentance+) +0.3 damage.
(except in Repentance+) 1
(in Repentance+) 2
Crack Jacks 5.100.354 Crack Jacks HP up. Don't swallow the prize! Grants one full Red Heart container and drops a random trinket. (in Repentance and Repentance+) Heals 1 additional Red Heart.pngRed Heart.
2
Cracked Orb 5.100.675 Cracked Orb Shards of knowledge Unlocks doors and reveals a random room on the map when Isaac takes damage.
1
Curse of the Tower 5.100.371 Curse of the Tower Embrace chaos Upon taking damage, spawns six Troll Bomb.pngTroll Bombs around the room, similar to the effect of XVI - The TowerXVI - The Tower.
0
Dark Prince's Crown 5.100.442 Dark Prince's Crown Loss is power (except in Repentance and Repentance+) When at exactly one Red Heart.pngRed Heart, +0.75 tears, +1.5 range, and +0.2 shot speed.
(in Repentance and Repentance+) When at exactly one Red Heart.pngRed Heart, +2 fire rate, +1.5 range, and +0.2 shot speed.
1
Dead Bird 5.100.117 Dead Bird Protective buddy After Isaac takes damage, spawns a flying familiar that chases enemies for the current room, dealing ~4 damage per second. (in Repentance+) As long as Isaac's HP is at one half heart ( no matter the type of heart), Dead Bird will remain active between rooms.
0
Dead Dove 5.100.185 Dead Dove Flight + spectral tears Grants spectral tears and flight.
3
Dessert 5.100.24 Dessert HP up Grants one full Red Heart container. (in Repentance and Repentance+) Heals 1 additional Red Heart.pngRed Heart.
1
Dinner 5.100.23 Dinner HP up Grants one full Red Heart container. (in Repentance and Repentance+) Heals 1 additional Red Heart.pngRed Heart.
1
E. Coli 5.100.236 E. Coli Turdy touch Enemies that touch Isaac are transformed into Poop.pngPoop.
(except in Repentance+) 1
(in Repentance+) 0
Empty Heart 5.100.676 Empty Heart It multiplies If Isaac has one red heart or fewer at the beginning of a floor, he gains an empty red heart container.
1
Fanny Pack 5.100.204 Fanny Pack Filled with goodies Has a chance to drop a random pickup when Isaac takes damage.
1
Fate 5.100.179 Fate Flight eternal Grants flight and one Eternal Heart.pngEternal Heart.
3
Giant Cell 5.100.658 Giant Cell Micro friends Causes Isaac to spawn Minisaac familiars when he takes damage, which chase and shoot at nearby enemies.
1
Gimpy 5.100.225 Gimpy Sweet suffering Gives chance of spawning a Soul Heart.pngSoul Heart when taking damage. Enemies have a chance to drop a Half Red Heart.pngHalf Red Heart after being killed.
2
Greed's Gullet 5.100.501 Greed's Gullet Money = health! Grants a Red Heart container for every 25 Penny.pngCoins Isaac has.
1
Habit 5.100.156 Habit Item martyr When Isaac is hit, his active item gains 1 room's worth of charge.
2
Hallowed Ground 5.100.543 Hallowed Ground Portable sanctuary Spawns a white poop familiar, which turns into a White Poop.pngWhite Poop when Isaac is hurt. White poop has an aura that increases tear fire rate and can block enemy shots. (in Repentance and Repentance+) The aura also increases damage by 20% and gives homing.
1
Holy Grail 5.100.184 Holy Grail Flight + HP up Grants flight and one Red Heart container. (in Repentance and Repentance+) Heals 1 additional Red Heart.pngRed Heart.
3
Hypercoagulation 5.100.724 Hypercoagulation Thick blooded After Isaac takes damage from an enemy or donates health, launches Red Heart.pngRed Hearts from Isaac that despawn after 1.5 seconds.
2
Immaculate Conception 5.100.413 Immaculate Conception Feed them love Upon picking up a certain amount of health, spawn a permanent angelic familiar.
1
Infestation 5.100.148 Infestation Fly revenge (except in Repentance and Repentance+) 1-3 Blue Flies randomly spawn every time Isaac gets hit.
(in Repentance and Repentance+) 2-6 Blue Flies randomly spawn every time Isaac gets hit.
0
Isaac's Heart 5.100.276 Isaac's Heart Protect it Isaac himself is now immune to all damage, and a heart familiar follows him. If the heart is hurt, Isaac is hurt. (in Repentance and Repentance+) The heart charges up as Isaac shoots, firing 8 blood shots, knocking back enemies, and leaving a puddle of creep when released.
0
It Hurts 5.100.560 It Hurts No it doesn't... Releases a ring of tears and increases fire rate for the current room when Isaac takes damage. (in Repentance+) Isaac's tears also leave pools of red creep for the rest of the room.
1
Judas' Shadow 5.100.311 Judas' Shadow Sweet revenge Upon death, respawns Isaac as Character Black Judas icon.pngBlack Judas with two Black Heart.pngBlack Hearts in the previous room.
3
Lazarus' Rags 5.100.332 Lazarus' Rags Eternal life? (except in Repentance and Repentance+) Upon dying, resurrect as Character Lazarus Risen icon.pngLazarus Risen in the current room with one Red Heart container and AnemicAnemic.
(in Repentance and Repentance+) Upon dying, resurrect as Character Lazarus Risen icon.pngLazarus Risen in the current room with one less Red Heart container, AnemicAnemic, and +0.5 Damage. Transform into Character Lazarus icon.pngLazarus when reaching the next floor.
1
Leprosy 5.100.525 Leprosy You're tearing me apart! Taking damage grants a body part orbital that blocks shots and deals contact damage, up to a maximum of three. The body parts are destroyed after blocking enough damage.
(except in Repentance+) 1
(in Repentance+) 0
Little C.H.A.D. 5.100.96 Little C.H.A.D. Gives kisses Spawns a familiar who drops a Half Red Heart.pngHalf Red Heart every 3 rooms.
2
Lord of the Pit 5.100.82 Lord of the Pit Demon wings Grants flight and +0.3 speed.
3
Lunch 5.100.22 Lunch HP up Grants one full Red Heart container. (in Repentance and Repentance+) Heals 1 additional Red Heart.pngRed Heart.
1
Maggy's Bow 5.100.312 Maggy's Bow HP up + you feel healthy Gives one Red Heart Container and doubles the healing provided by Red Heart.pngRed Hearts. (in Repentance and Repentance+) Also heals 1 Red Heart when obtained.
2
Magic Scab 5.100.253 Magic Scab HP + luck up Grants one full Red Heart container, +1 luck. (in Repentance and Repentance+) Heals 1 additional Red Heart.pngRed Heart.
2
Marrow 5.100.541 Marrow HP up? Grants one Bone Heart.pngBone Heart and spawns three Red Heart.pngRed Hearts.
1
MEAT! 5.100.193 MEAT! DMG + HP up Grants one full Red Heart container, +0.3 damage. (in Repentance and Repentance+) Heals 1 additional Red Heart.pngRed Heart
2
Midas' Touch 5.100.202 Midas' Touch Golden touch Enemies that touch Isaac are temporarily petrified and turn to gold. Any enemy killed while in this state will drop Penny.pngPennies.
(except in Repentance+) 2
(in Repentance+) 1
Midnight Snack 5.100.456 Midnight Snack HP up Grants one full Red Heart container. (in Repentance and Repentance+) Heals 1 additional Red Heart.pngRed Heart.
1
Milk! 5.100.436 Milk! Don't cry over it... (except in Repentance+) Spawns a glass familiar that follows Isaac. After Isaac takes damage, the milk spills, and he gains -2 tear delay ((in Repentance and Repentance+) +1.0 fire rate) until leaving the room
(in Repentance+) Spawns a glass familiar that follows Isaac. The milk will block projectiles, and upon blocking 10, the milk spills, giving Isaac +1.0 fire rate for the rest of the floor.
1
Missing Page 2 5.100.262 Missing Page 2 Evil up. Your enemies will pay! Grants one Black Heart.pngBlack Heart. Upon taking damage that reduces Isaac's health to one heart or less, deals damage to all enemies in the room. (in Repentance and Repentance+) Increases the damage of Black Heart.pngBlack Hearts and The NecronomiconThe Necronomicon-like effects by 40.
0
Mystery Egg 5.100.539 Mystery Egg Sacrificial insemination Spawns an egg familiar, which hatches a random friendly monster when Isaac is hurt once per room. The power of the monster improves for each consecutive room cleared without taking damage.
(except in Repentance+) 1
(in Repentance+) 0
Old Bandage 5.100.219 Old Bandage HP up Grants an empty Red Heart container. Adds a chance of dropping a Red Heart.pngRed Heart after taking damage.
2
Orphan Socks 5.100.571 Orphan Socks Speed up + your feet feel stronger Prevents creep and floor spikes from damaging Isaac. Also gives Isaac +0.3 speed and 2 Soul Heart.pngSoul Hearts.
2
Piggy Bank 5.100.227 Piggy Bank My life savings Gives 3 Penny.pngPennies on pick-up. Every time Isaac is damaged, he will drop one or two additional pennies.
1
PJs 5.100.428 PJs You feel cozy Grants 4 Soul Heart.pngSoul Hearts and fully restores Isaac's health.
2
Placenta 5.100.218 Placenta Regeneration + HP up Grants one full Red Heart container, and a chance to regenerate a Half Red Heart.pngHalf Red Heart of health every minute of gameplay.
2
Raw Liver 5.100.16 Raw Liver HP up Grants 2 Red Heart containers and completely restores health.
2
Rotten Meat 5.100.26 Rotten Meat HP up Grants one full Red Heart container. (in Repentance and Repentance+) Heals 1 additional Red Heart.pngRed Heart.
1
Sanguine Bond 5.100.692 Sanguine Bond He awaits your offering Spawns a special set of spikes in the Devil RoomDevil Room. Taking damage from the spikes has a chance to grant a reward.
1
Scapular 5.100.142 Scapular Pray for a miracle Once per room, when Isaac is reduced to his last half heart, he is granted one Soul Heart.pngSoul Heart.
2
Shard of Glass 5.100.448 Shard of Glass Blood and guts! (except in Repentance and Repentance+) Upon taking damage, Isaac has a chance to drop a full red heart, gain 5 range, and leave a trail of damaging red creep for the current room.
(in Repentance and Repentance+) Taking damage causes Isaac to bleed, spraying a volley of blood in the direction he fires. Bleeding will eventually damage him, but it can be stopped by picking up a Red Heart.pngRed Heart.
1
Sharp Plug 5.100.205 Sharp Plug Infinite charge... at a cost Damages Isaac in exchange for fully recharging Isaac's current activated item.
2
Spiderbaby 5.100.211 Spiderbaby Spider revenge (except in Repentance and Repentance+) Spawns 1-2 Blue Spiders when Isaac takes damage.
(in Repentance and Repentance+) Spawns 3-5 Blue Spiders when Isaac takes damage.
0
Spirit of the Night 5.100.159 Spirit of the Night Scary Grants spectral tears and flight.
3
Stem Cells 5.100.176 Stem Cells HP + shot speed up Grants one full Red Heart container and +0.16 shot speed. (in Repentance and Repentance+) Heals 1 additional Red Heart.pngRed Heart
1
Super Bandage 5.100.92 Super Bandage +2 hearts Grants one full Red Heart container and 2 Soul Heart.pngSoul Hearts.
2
Supper 5.100.707 Supper HP up Grants one full Red Heart container. Heals 1 additional Red Heart.pngRed Heart.
1
The Black Bean 5.100.180 The Black Bean Toot on touch (except in Repentance and Repentance+) When taking damage, Isaac farts, poisoning enemies in range.
(in Repentance and Repentance+) When taking damage, Isaac farts five times, poisoning and knocking back nearby enemies and leaving lingering poison clouds.
0
The Body 5.100.334 The Body I feel all Adds 3 Red Heart Containers.
3
The Ladder 5.100.60 The Ladder Building bridges Allows Isaac to walk across gaps one square across by automatically placing a ladder between the two walkable sections.
1
The Relic 5.100.98 The Relic Soul generator Spawns a cross familiar that drops a Soul Heart.pngSoul Heart after clearing enough rooms.
3
The Wafer 5.100.108 The Wafer Damage resistance Most sources of damage that would cause more than one-half heart of damage are reduced to one-half heart instead.
4
Thunder Thighs 5.100.314 Thunder Thighs HP up + speed down + you feel stompy Destroys rocks upon contact with Isaac. Adds one Red Heart container and lowers Speed.
1
Transcendence 5.100.20 Transcendence We all float down here... Grants flight.
(except in Repentance+) 3
(in Repentance+) 2
Varicose Veins 5.100.452 Varicose Veins I'm leaking... Taking damage releases a ring of 10 high damage tears.
(except in Repentance+) 1
(in Repentance+) 0
Vengeful Spirit 5.100.702 Vengeful Spirit Hot blooded After taking damage, spawns an orbital wisp that lasts for the entire floor, up to a maximum of six. They fire tears but do not block shots.
1
(in Repentance+) Stigmata 5.100.138 Stigmata DMG + HP up +0.3 damage, grants one full Red Heart container. (in Repentance and Repentance+) Heals 1 additional Red Heart.pngRed Heart.
2
(except in Repentance+) Brittle Bones 5.100.549 Brittle Bones Everything hurts Replaces all Red Heart.pngRed Heart Containers with 6 empty Bone Heart.pngBone Hearts. (except in Repentance and Repentance+) Upon losing a Bone Heart, Isaac fires bones in 8 directions and permanently gains a tears up. (in Repentance and Repentance+) Upon losing a Bone Heart, Isaac fires bones in 8 directions and permanently gains a fire rate up.
3
(except in Repentance+) Ouija Board 5.100.115 Ouija Board Spectral tears + tears up Grants spectral tears that travel through obstacles (but not enemies). (in Repentance and Repentance+) +0.5 tears.
2
(except in Repentance+) Rosary 5.100.72 Rosary Tears + faith up Grants 3 Soul Heart.pngSoul Hearts. Causes The BibleThe Bible to appear in any item pool. (in Repentance and Repentance+) +0.5 tears.
2
(except in Repentance+) The Virus 5.100.13 The Virus Poison touch + speed up Isaac poisons enemies on contact. (except in Repentance and Repentance+) -0.1 speed. (in Repentance and Repentance+) +0.2 speed. (in Afterbirth and Afterbirth †) Poisoned enemies have a chance to drop a black heart when killed.
2


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