Seraphim (Transformation)

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(except in Rebirth)

After obtaining 3 holy items listed below ((in Repentance and Repentance+) 3 items with the angel item tag), Isaac will gain 3 Soul Heart.pngSoul Hearts and permanent flight.

Activated Collectibles

Name ID Icon Quote Description (in Repentance and Repentance+) Quality
The Bible 5.100.33
The Bible4 rooms
Temporary flight
Grants flight for the current room. Instantly kills Boss Mom ingame.pngMom, Boss Mom's Heart ingame.pngMom's Heart, and Boss It Lives! ingame.pngIt Lives! when activated, but kills Isaac when used on Boss Satan ingame.pngSatan.
1

Passive Collectibles

Name ID Icon Quote Description (in Repentance and Repentance+) Quality
Dead Dove 5.100.185 Dead Dove
Flight + spectral tears
Grants spectral tears and flight.
3
The Halo 5.100.101 The Halo
All stats up
(except in Repentance and Repentance+) Grants one full Red Heart container, +0.3 damage, +0.2 tears, +0.25 range, +0.3 speed, and +0.5 tear falling speed.
(in Repentance and Repentance+) Grants one full Red Heart container, +0.3 damage, +0.2 tears, +1.5 range, and +0.3 speed. Heals 1 additional Red Heart.pngRed Heart.
(except in Repentance+)
2
(in Repentance+)
3
Holy Grail 5.100.184 Holy Grail
Flight + HP up
Grants flight and one Red Heart container. (in Repentance and Repentance+) Heals 1 additional Red Heart.pngRed Heart.
3
Holy Mantle 5.100.313 Holy Mantle
Holy shield
Grants a shield that negates the first instance of damage taken from a hostile source once per room.
4
Mitre 5.100.173 Mitre
(except in Repentance and Repentance+)
You feel blessed
(in Repentance and Repentance+)
Blessing of purity
Grants a chance of converting any Red Heart.pngRed Heart pickups that spawn into Soul Heart.pngSoul Hearts instead.
3
Rosary 5.100.72 Rosary
(except in Repentance and Repentance+)
Faith up
(in Repentance and Repentance+)
Tears + faith up
Grants 3 Soul Heart.pngSoul Hearts. Causes The BibleThe Bible to appear in any item pool. (in Repentance and Repentance+) +0.5 tears.
2
(except in Repentance and Repentance+) Guardian Angel 5.100.112 Guardian Angel
Extra protection
Spawns an orbital familiar that blocks enemy shots, deals 7 damage per tick on contact, and increases the speed of all orbital familiars.
(except in Repentance+)
2
(in Repentance+)
1
(except in Repentance and Repentance+) Sworn Protector 5.100.363 Sworn Protector
Protective friend
Spawns an orbital familiar which does (except in Repentance and Repentance+) 105 / (in Repentance and Repentance+) 53 damage per second and attracts and blocks enemy shots. Upon blocking 10 shots in a room, it drops an Eternal Heart.pngEternal Heart.
(except in Repentance+)
3
(in Repentance+)
2
(in Repentance and Repentance+) Celtic Cross 5.100.162 Celtic Cross
(except in Repentance and Repentance+)
You feel blessed
(in Repentance and Repentance+)
Blessing of protection
Grants a chance to trigger the Book of ShadowsBook of Shadows effect upon taking damage, creating a shield that nullifies all types of damage for 7 seconds.
1
(in Repentance and Repentance+) Divine Intervention 5.100.568 Divine Intervention
Double tap shield
Double tapping a fire key creates a shield that pushes away enemies and reflects enemy projectiles and lasers.
(except in Repentance+)
2
(in Repentance+)
1
(in Repentance and Repentance+) Godhead 5.100.331 Godhead
God tears
(except in Repentance and Repentance+) Grants homing tears with a damaging halo. +0.5 Damage, -0.3 Tears -0.3 Shot Speed, +0.8 Tear Falling Speed, and +1.2 Range.
(in Repentance and Repentance+) Grants homing tears with a damaging halo. +0.5 Damage, -0.3 Tears, and -0.3 Shot Speed.
4
(in Repentance and Repentance+) Holy Light 5.100.374 Holy Light
(except in Repentance and Repentance+)
Holy shot!
(in Repentance and Repentance+)
Holy death shot
Adds a chance to fire holy tears, which will create a damaging light beam in the area if they hit an enemy.
3
(in Repentance and Repentance+) Immaculate Heart 5.100.573 Immaculate Heart
Halo of tears
Adds one Red Heart Container and fully restores health. x1.2 damage multiplier. Isaac will occasionally fire extra tears that orbit around him.
3
(in Repentance and Repentance+) Revelation 5.100.643 Revelation
Awaken your faith
Grants flight. In addition to tears, Isaac can charge up and fire a powerful holy laser. (except in Repentance+) Also grants two Soul Heart.pngSoul Hearts.
4
(in Repentance and Repentance+) Sacred Heart 5.100.182 Sacred Heart
Homing shots + DMG up
(except in Repentance and Repentance+) Adds a Red Heart Container. Grants homing tears, a x2.3 Damage multiplier, +1 flat Damage, -0.4 Tears, -0.25 Shot Speed, and +4.125 Range.
(in Repentance and Repentance+) Adds a Red Heart Container. Grants homing tears, a x2.3 Damage multiplier, +1 flat Damage, -0.4 Tears, and -0.25 Shot Speed.
4
(in Repentance and Repentance+) Salvation 5.100.696 Salvation
Divine protection
Gives Isaac a halo that summons beams of light on enemies inside it. The halo grows larger the more times Isaac has taken damage this floor.
3
(in Repentance and Repentance+) Sacred Orb 5.100.691 Sacred Orb
Destined for greatness
Prevents items of quality 0-1 from appearing, and items of quality 2 from appearing 33% of the time. Quest items are unaffected.
4
(in Repentance and Repentance+) Scapular 5.100.142 Scapular
(except in Repentance and Repentance+)
You have been blessed
(in Repentance and Repentance+)
Pray for a miracle
Once per room, when Isaac is reduced to his last half heart, he is granted one Soul Heart.pngSoul Heart.
2
(in Repentance+) Seraphim 5.100.390 Seraphim
Sworn friend
Spawns an angel familiar who follows Isaac and fires homing tears which deal 10 damage and have 75% shot speed.
3

Notes

  • (except in Repentance+) Despite having the same name, the familiar Seraphim does not contribute to the Seraphim transformation.
  • Picking up and dropping multiple, distinct copies of The Bible will count each copy towards the transformation. This makes Rosary and to a lesser degree, Rosary BeadRosary Bead especially helpful in gaining the transformation.