Louse
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Louse is a trinket added in The Binding of Isaac: Afterbirth.
Effects
- Occasionally spawns a Blue Spider.
- Effect only occurs when in an uncleared room.
- After the first spider spawns, there is a 50% chance of one spawning after 30 seconds and a guaranteed spawn a minute later.
Synergies
Golden Trinket / 
Mom's Box / 
Louse : Each copy of the effect will spawn an additional spider every time one is spawned.
In-game Footage
Trivia
- The phrase "Itchy, tasty..." is a reference to the Keeper's Diary from Resident Evil. The Diary describes the slow transformation of a researcher into a zombie as his entries become less and less coherent due to neural decay caused by t-Virus infection. His final entry consists of two words: "Itchy. Tasty.".
 The Binding of Isaac: Rebirth
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