Berkano
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Berkano is an unlockable rune.
Effects
Spawns 3 Blue Flies and 3 Blue Spiders.
Gives Isaac 3 standard 
Abyss locusts for the room.
Synergies
Tarot Cloth: Spawns 6 Blue Flies and 6 Blue Spiders.
Fish Tail: Doubles the flies and spiders spawned.
BFFS! / 
Hive Mind: Increases the locusts' size and damage by 25%.
- These two items don't stack.
Extension Cord: Electricity will flow between Isaac and the locusts.
Ipecac: Locusts gain a flat +2 damage.
Interactions
Tarot Cloth: No effect.
In-game Footage
- TBA
 The Binding of Isaac: Rebirth
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