All Bosses (Bosses)

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Bosses

Bosses

Boss Monstro portrait.png
Boss Gemini portrait.png
Boss Steven portrait.png
 Boss Dingle portrait.png
Monstro Gemini Steven Needs to be unlocked Dingle
Boss Gurglings portrait.png
Boss Larry Jr. portrait.png
Boss The Duke of Flies portrait.png
 Boss Widow portrait.png
Gurglings Larry Jr. The Duke of Flies Widow
Boss Blighted Ovum portrait.png
Boss The Haunt portrait.png
 Boss Pin portrait.png
Boss Famine portrait.png
Blighted Ovum The Haunt Pin Famine Needs to be unlocked
Boss Fistula portrait.png
Boss Chub portrait.png
Boss C.H.A.D. portrait.png
Boss Gurdy portrait.png
Fistula Chub C.H.A.D. Needs to be unlocked Gurdy
Boss Mega Fatty portrait.png
 Boss Mega Maw portrait.png
Boss Gurdy Jr. portrait.png
Boss Peep portrait.png
Mega Fatty Mega Maw Gurdy Jr. Peep
Boss The Husk portrait.png
Boss The Hollow portrait.png
Boss Carrion Queen portrait.png
Boss Dark One portrait.png
The Husk The Hollow Carrion Queen Dark One
Boss Polycephalus portrait.png
Boss The Wretched portrait.png
Boss Pestilence portrait.png
Boss Monstro II portrait.png
Polycephalus The Wretched Pestilence Needs to be unlocked Monstro II
Boss Gish portrait.png
Boss The Cage portrait.png
Boss The Gate portrait.png
Boss Loki portrait.png
Gish Needs to be unlocked The Cage The Gate Loki
Boss The Adversary portrait.png
Boss The Bloat portrait.png
Boss Mask of Infamy portrait.png
Boss War portrait.png
The Adversary The Bloat Mask Of Infamy War Needs to be unlocked
Boss Blastocyst portrait.png
Boss Mama Gurdy portrait.png
Boss Scolex portrait.png
Boss Mr. Fred portrait.png
Blastocyst Mama Gurdy Scolex Mr. Fred
Boss Lokii portrait.png
Boss Daddy Long Legs portrait.png
Boss Triachnid portrait.png
Boss Teratoma portrait.png
Lokii Daddy Long Legs Triachnid Needs to be unlocked Teratoma
Boss Death portrait.png
Boss Conquest portrait.png
Boss Headless Horseman portrait.png
Boss The Fallen portrait.png
Death Needs to be unlocked Conquest Needs to be unlocked Headless Horseman Needs to be unlocked The Fallen Devil Room Icon.png

Afterbirth (except in Rebirth)

Boss Dangle portrait.png
Boss Turdlings portrait.png
Boss Little Horn portrait.png
Boss Rag Man portrait.png
Dangle Needs to be unlocked Turdlings Needs to be unlocked Little Horn Needs to be unlocked Rag Man Needs to be unlocked
Boss The Stain portrait.png
Boss The Forsaken portrait.png
Boss The Frail portrait.png
Boss Brownie portrait.png
The Stain Needs to be unlocked The Forsaken Needs to be unlocked The Frail Needs to be unlocked Brownie Needs to be unlocked

Afterbirth+ (except in Rebirth and Afterbirth)

Boss Big Horn portrait.png
Boss Rag Mega portrait.png
Boss Sisters Vis portrait.png
Boss The Matriarch portrait.png
Big Horn Needs to be unlocked Rag Mega Needs to be unlocked Sisters Vis Needs to be unlocked The Matriarch Needs to be unlocked

Repentance (in Repentance and Repentance+)

Boss Baby Plum portrait.png
Boss Bumbino portrait.png
Boss Reap Creep portrait.png
Boss The Pile portrait.png
Baby Plum Needs to be unlocked Bumbino Needs to be unlocked Reap Creep Needs to be unlocked The Pile Needs to be unlocked
Boss The Rainmaker portrait.png
Boss Min-Min portrait.png
Boss Lil Blub (Downpour) portrait.png
Boss Wormwood (Downpour) portrait.png
The Rainmaker Needs to be unlocked Min-Min Needs to be unlocked Lil Blub Needs to be unlocked Wormwood Needs to be unlocked
Boss Clog portrait.png
Boss Colostomia portrait.png
Boss Turdlet portrait.png
Boss Tuff Twins portrait.png
Clog Needs to be unlocked Colostomia Needs to be unlocked Turdlet Needs to be unlocked Tuff Twins Needs to be unlocked
Boss Hornfel portrait.png
Boss Great Gideon portrait.png
Boss Singe portrait.png
Boss The Shell portrait.png
Hornfel Needs to be unlocked Great Gideon Needs to be unlocked Singe Needs to be unlocked The Shell Needs to be unlocked
Boss Clutch portrait.png
Boss The Siren portrait.png
Boss The Heretic portrait.png
Boss The Visage portrait.png
Clutch Needs to be unlocked The Siren Needs to be unlocked The Heretic Needs to be unlocked The Visage Needs to be unlocked
Boss The Horny Boys portrait.png
Boss Chimera portrait.png
Boss The Scourge portrait.png
Boss Rotgut portrait.png
The Horny Boys Needs to be unlocked Chimera Needs to be unlocked The Scourge Needs to be unlocked Rotgut Needs to be unlocked
Boss Ultra Famine ingame.png
Boss Ultra Pestilence ingame.png
Boss Ultra War ingame.png
Boss Ultra Death ingame.png
Ultra Famine Needs to be unlocked Ultra Pestilence Needs to be unlocked Ultra War Needs to be unlocked Ultra Death Needs to be unlocked
Boss Dogma portrait.png
Dogma Needs to be unlocked

Final Bosses

Boss Mom portrait.png
Boss Mom's Heart portrait.png
Boss It Lives! portrait.png
Boss Satan portrait.png
Mom Mom's Heart Needs to be unlocked It Lives! Needs to be unlocked Satan Needs to be unlocked
Boss Isaac portrait.png
Boss The Lamb portrait.png
???
Boss Mega Satan portrait.png
Isaac Needs to be unlocked The Lamb Needs to be unlocked ??? Needs to be unlocked Mega Satan Needs to be unlocked
Boss Hush portrait.png
Boss Delirium portrait.png
Boss Mother portrait.png
Hush (except in Rebirth) Needs to be unlocked Delirium (except in Rebirth and Afterbirth) Needs to be unlocked Mother (in Repentance and Repentance+) Needs to be unlocked
Boss The Beast ingame.png
Boss Ultra Greed portrait.png
Boss Ultra Greedier ingame.png
The Beast (in Repentance and Repentance+) Needs to be unlocked Ultra Greed (except in Rebirth) Ultra Greedier (except in Rebirth and Afterbirth) Needs to be unlocked
Boss Monstro portrait.png Bosses Boss Monstro portrait.png
Chapter 1
BasementCellarBurning Basement
 Monstro • Gemini • Steven • Dingle • Gurglings • Larry Jr. • The Duke of Flies • Widow • Blighted Ovum • The Haunt • Pin • Famine • The Fallen • Headless Horseman
(except in Rebirth) Dangle • Turdlings • Little Horn • Rag Man
(in Repentance and Repentance+)Baby Plum
(in Repentance and Repentance+) Chapter 1.5
DownpourDross
 The Rainmaker • Min-Min • Lil Blub • Wormwood • Clog • Colostomia • Turdlet
Chapter 2
CavesCatacombsFlooded Caves
 Fistula • Chub • C.H.A.D. • Gurdy • Mega Fatty • Mega Maw • Gurdy Jr. • Peep • The Husk • The Hollow • Carrion Queen • Dark One • Polycephalus • The Wretched • Pestilence • The Fallen • Headless Horseman
(except in Rebirth) The Stain • The Frail • The Forsaken
(except in Rebirth and Afterbirth) Big Horn • Rag Mega
(in Repentance and Repentance+)Bumbino
(in Repentance and Repentance+) Chapter 2.5
MinesAshpit
 Reap Creep • Tuff Twins • Hornfel • Great Gideon • The Pile • The Shell • Singe • Clutch
Chapter 3
DepthsNecropolisDank Depths
 Monstro II • Gish • The Cage • The Gate • Loki • The Adversary • The Bloat • Mask of Infamy • War • The Fallen • Headless Horseman • Mom
(except in Rebirth) Brownie
(except in Rebirth and Afterbirth) Sisters Vis
(in Repentance and Repentance+) Reap Creep • The Pile
(in Repentance and Repentance+) Chapter 3.5
MausoleumGehenna
 The Siren • The Heretic • The Visage • The Horny Boys • Mom • Mom's Heart
Chapter 4
WombUteroScarred Womb
 Blastocyst • Mama Gurdy • Scolex • Mr. Fred • Lokii • The Bloat • Daddy Long Legs • Triachnid • Teratoma • Death • Conquest • The Fallen • Headless Horseman • Mom's Heart • It Lives!
(except in Rebirth and Afterbirth)The Matriarch
(except in Rebirth) ???
???
 Hush
(in Repentance and Repentance+) Corpse
Corpse
 Chimera • The Scourge • Rotgut • Mother
Chapter 5
SheolCathedral
 Satan • Isaac
Chapter 6
Dark RoomChest
 The Lamb • ??? • Mega Satan
(except in Rebirth and Afterbirth) The Void
The Void
 Delirium
(in Repentance and Repentance+) Home
Home
 Dogma • Ultra Famine • Ultra Pestilence • Ultra War • Ultra Death • The Beast
(except in Rebirth) Greed Mode
Ultra Greed
 Ultra Greed
(except in Rebirth and Afterbirth)Ultra Greedier
SmallIsaac.pngThe Binding of Isaac: RebirthSmallIsaac.png
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